- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
Rp40
Average price
Rp69
Fastest journey
8 h 20 m
Average duration
8 h 41 m
Buses per day
43
Distance
517 km
The best way to find a cheap bus ticket from Warsaw to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Warsaw to Prague will cost around Rp69 if you buy it on the day, but the cheapest tickets can be found for only Rp40.
Of the 43 buses that leave Warsaw for Prague on Fri, Aug 14, 31 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Aug 14 the direct buses cover the 517 km distance in an average of 8 h 41 m but if you time it right, some buses will get you there in just 8 h 20 m .
On Fri, Aug 14 the slowest buses will take 9 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBusOmio recommends booking the train as it is the most popular option from Warsaw to Prague among Omio's users. If you are prioritising price take the train with prices starting from Rp18. For those with little time consider booking a flight which can get you there in 2h 52m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a train costs an average of Rp18, and a flight costs an average of Rp165.
Distance: 321 miles (517 km)
| Bus | Most popular Train | Flight |
|---|---|---|
Rp37 Average price | Rp34 Average price Cheapest | Rp358 Average price |
9h 52m Average total duration 9h 22m Onboard + 30m Additional time* | 9h 45m Average total duration 9h 15m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 2h 52m Onboard + 3h 0m Additional time* |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.1kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Warsaw to Prague:
A train is Rp3 less than a bus for this route with tickets for a bus from Warsaw to Prague costing on average Rp37.
A train is Rp324 less than a flight for this route with tickets for a flight from Warsaw to Prague costing on average Rp358.
Other travel options to Prague take longer:
Train takes on average 9h 15m.
Bus takes on average 9h 22m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 10:10AM | Duration 9h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp43 |
Operator FlixBus | Departure Time 12:35AM | Arrival Time 10:40AM | Duration 10h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp36 |
Operator FlixBus | Departure Time 02:50AM | Arrival Time 03:50PM | Duration 13h00 | Departure days Sat, Sun | Cheapest price Rp68 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 04:00PM | Duration 11h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp52 |
Operator FlixBus | Departure Time 04:50AM | Arrival Time 02:45PM | Duration 9h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp36 |
Operator FlixBus | Departure Time 05:10AM | Arrival Time 02:45PM | Duration 9h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp36 |
Operator BlaBlaCar | Departure Time 05:40AM | Arrival Time 12:50PM | Duration 7h10 | Departure days Sun | Cheapest price Rp52 |
Operator Ecolines | Departure Time 06:30AM | Arrival Time 05:45PM | Duration 11h15 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price Rp36 |
Operator FlixBus | Departure Time 07:00AM | Arrival Time 05:40PM | Duration 10h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp38 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 07:30PM | Duration 10h45 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp34 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 08:40PM | Duration 11h25 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp37 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 07:45PM | Duration 10h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp38 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 08:40PM | Duration 10h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp32 |
Operator FlixBus | Departure Time 11:45AM | Arrival Time 11:35PM | Duration 11h50 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp51 |
Operator FlixBus | Departure Time 12:18PM | Arrival Time 09:35PM | Duration 9h17 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp37 |
Operator BlaBlaCar | Departure Time 12:20PM | Arrival Time 07:20PM | Duration 7h00 | Departure days Fri | Cheapest price Rp39 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 09:10PM | Duration 8h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp37 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 11:20PM | Duration 10h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp52 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 02:25AM | Duration 12h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp51 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 11:35PM | Duration 8h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp37 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 12:50AM | Duration 7h50 | Departure days Fri | Cheapest price Rp25 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 01:00AM | Duration 7h30 | Departure days Mon | Cheapest price Rp40 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 05:20AM | Duration 11h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp50 |
Operator FlixBus | Departure Time 07:23PM | Arrival Time 07:00AM | Duration 11h37 | Departure days Sat, Sun | Cheapest price Rp65 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 07:00AM | Duration 10h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp41 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 06:25AM | Duration 9h25 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp41 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 06:25AM | Duration 9h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp35 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 08:00AM | Duration 10h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp33 |
Operator FlixBus | Departure Time 10:05PM | Arrival Time 08:00AM | Duration 9h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp38 |
Operator FlixBus | Departure Time 10:20PM | Arrival Time 11:00AM | Duration 12h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price Rp51 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 08:40PM | Duration 21h10 | Departure days Thu | Cheapest price Rp123 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 10:10AM | Duration 10h25 | Departure days Everyday | Cheapest price Rp43 |
Operator Ecolines | Departure Time 11:50PM | Arrival Time 09:20AM | Duration 9h30 | Departure days Everyday | Cheapest price Rp36 |
The table below shows live departures for Warsaw to Prague buses for tomorrow, Friday, August 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 12:15 AM Warszawa, Dworzec Zachodni | 9h55 | 10:10 AM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 12:15 AM Warszawa, Dworzec Zachodni | 10h25 | 10:40 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 12:35 AM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 9h35 | 10:10 AM Praha, Černý Most | 0 transfersDirect | |
FlixBus · FlixBus | 12:35 AM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 12h25 | 1:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 12:35 AM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 10h05 | 10:40 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 4:25 AM Warszawa, Dworzec Zachodni | 11h35 | 4:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 4:50 AM Warszawa, Aleje Jerozolimskie (Dworzec Centralny 06) | 9h55 | 2:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 4:50 AM Warszawa, Dworzec Zachodni | 11h40 | 4:30 PM Praha, Roztyly | 1 transfer | |
FlixBus | 5:10 AM Warszawa, Dworzec Zachodni | 9h35 | 2:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 7:00 AM Warszawa, Dworzec Zachodni | 10h40 | 5:40 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 8:45 AM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 10h45 | 7:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:15 AM Warszawa, Metro Marymont 11 | 11h00 | 8:15 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 9:15 AM Warszawa, Dworzec Zachodni | 10h15 | 7:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:15 AM Warszawa, Metro Marymont 11 | 10h30 | 7:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 9:15 AM Warszawa, Metro Marymont 11 | 11h25 | 8:40 PM Praha, Černý Most | 1 transfer | |
FlixBus | 9:40 AM Warszawa, Dworzec Zachodni | 10h35 | 8:15 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 9:40 AM Warszawa, Dworzec Zachodni | 10h05 | 7:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 9:40 AM Warszawa, Dworzec Zachodni | 11h00 | 8:40 PM Praha, Černý Most | 1 transfer | |
FlixBus | 10:10 AM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 10h05 | 8:15 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 10:10 AM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 9h35 | 7:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:10 AM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 10h30 | 8:40 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:45 AM Warszawa, Dworzec Autobusowy Metro Młociny | 11h50 | 11:35 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus | 12:18 PM Warszawa, Metro Marymont 11 | 8h52 | 9:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 12:18 PM Warszawa, Metro Marymont 11 | 9h17 | 9:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 12:50 PM Warszawa, Dworzec Zachodni | 8h45 | 9:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 12:50 PM Warszawa, Dworzec Zachodni | 8h20 | 9:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus · FlixBus | 1:00 PM Warszawa, Dworzec Zachodni | 10h20 | 11:20 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 2:20 PM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 12h05 | 2:25 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 3:05 PM Warszawa, Dworzec Zachodni | 8h30 | 11:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 6:00 PM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 10h50 | 4:50 AM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus | 6:00 PM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 11h20 | 5:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 8:25 PM Warszawa, Metro Stadion Narodowy 01 | 10h00 | 6:25 AM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 8:25 PM Warszawa, Metro Stadion Narodowy 01 | 10h35 | 7:00 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 PM Warszawa, Dworzec Zachodni | 10h00 | 7:00 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 PM Warszawa, Dworzec Zachodni | 9h25 | 6:25 AM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 9:25 PM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 9h00 | 6:25 AM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 9:25 PM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 9h35 | 7:00 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:40 PM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 10h20 | 8:00 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 10:05 PM Warszawa, Dworzec Zachodni | 9h55 | 8:00 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:20 PM Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy | 12h40 | 11:00 AM Praha, Roztyly | 1 transfer | |
FlixBus | 11:45 PM Warszawa, Dworzec Autobusowy Metro Młociny | 10h25 | 10:10 AM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 11:45 PM Warszawa, Dworzec Autobusowy Metro Młociny | 10h55 | 10:40 AM Praha, ÚAN Florenc | 0 transfersDirect | |
![]() | 11:50 PM Warszawa, Dworzec Zachodni | 9h30 | 9:20 AM Praha, ÚAN Florenc | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Warsaw to Prague run on average 40 times per day, taking around 9h 22m. Cheap bus tickets for this journey start at Rp20 but you can travel from only Rp18 by train.
There are 30 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 321 miles (517 km) distance in 8h 30m.
Distance 321 miles (517 km) |
Average bus duration 9h 22m |
Cheapest ticket price Rp20 |
Buses per day 40 |
Direct buses 30 |
Fastest bus 8h 30m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 84 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Buses in Europe are an affordable way to travel between cities. A number of bus companies service both domestic and international routes. Buses from Warsaw to Prague depart regularly throughout the day from early morning until late in the evening. There are equally frequent and regular weekend buses. PolskiBus, Infobus, Ecolines, and Flixbus all offer services and most journeys are direct, while others require one change. Journey times can take as little as 10 hours to arrive in Prague.
Return buses from Prague to Warsaw | Compare all modes of traveling from Warsaw to Prague | Or learn more about buses to Prague
Average prices for buses from Warsaw to Prague when you book in advance
Booking Period |
Average Price |
|---|---|
Same Day |
€44 |
1 Day in Advance |
€24 |
1 Week in Advance |
€21 |
2 Weeks in Advance |
€21 |
1 Month in Advance |
€20 |
3 Months in Advance |
€20 |
Warsaw to Prague Buses: General Information
Buses are a fast and convenient way to travel from Warsaw to Prague. Buses are usually cheaper than taking a flight or the train.
Based on Omio's travel data, as the table above clearly illustrates, ticket prices on Warsaw to Prague buses decrease the further they are booked in advance:
Find answers to the most common questions about traveling from Warsaw to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Warsaw to Prague buses use the Warszawa, Dworzec Zachodni to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Černý Most. Use this guide to compare Warsaw and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Warszawa, Dworzec Zachodni is 3 km from Warsaw city centre. Public transport options include:
Warszawa, Dworzec Zachodni has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Polska (in the station), Fast Food Express (in the station), Bistro Warszawa (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and ticket counters.
Ticket office support is available at Warszawa, Dworzec Zachodni.
Available at Warszawa, Dworzec Zachodni: Parking, Taxis, WC.
Accessibility facilities are available at Warszawa, Dworzec Zachodni: Elevators, ramps.
Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy is 7 km from Warsaw city centre. Public transport options include:
Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Terminal (in the station), Bistro Chopin (in the station), Pierogi Place (0.5 km).
Free Wi-Fi. ATMs are located inside the terminal, near the main entrance.
Ticket office support is available at Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy.
Available at Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy: Parking, Taxis, WC.
Accessibility facilities are available at Warsaw, Airport Lotnisko Chopina - Terminal Autokarowy: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Černý Most is 11 km from Prague city centre. Public transport options include:
Praha, Černý Most has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Černý Most (in the station), Czech Bistro (in the station), Fast Food Express (in the station).
Free Wi-Fi. ATMs are located near the entrance and in the main concourse.
Ticket office support is available at Praha, Černý Most.
Available at Praha, Černý Most: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Černý Most: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Here are some other resources that might have the information you need