- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
€59
Average price
€62
Fastest journey
14 h 40 m
Average duration
16 h 22 m
Buses per day
10
Distance
717 km
The best way to find a cheap bus ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Prague will cost around €62 if you buy it on the day, but the cheapest tickets can be found for only €59.
Of the 10 buses that leave Brussels for Prague on Wed, Aug 26, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 26 the direct buses cover the 717 km distance in an average of 16 h 22 m but if you time it right, some buses will get you there in just 14 h 40 m .
On Wed, Aug 26 the slowest buses will take 17 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €45. For those with little time consider booking a flight which can get you there in 2h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €45, and a flight costs an average of €21.
Distance: 445 miles (717 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€70 Average price Cheapest | €151 Average price | €113 Average price | €151 Average price (fuel + tolls) |
15h 42m Average total duration 15h 12m Onboard + 30m Additional time* | 5h 6m Average total duration Fastest 2h 6m Onboard + 3h 0m Additional time* | 13h 23m Average total duration 12h 53m Onboard + 30m Additional time* | 8h 38m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Prague:
A bus is €43 less than a train for this route with tickets for a train from Brussels to Prague costing on average €113.
A bus is €81 less than a flight for this route with tickets for a flight from Brussels to Prague costing on average €151.
Other travel options to Prague take longer:
Train takes on average 12h 53m.
Bus takes on average 15h 12m.
Tickets start at around €70 compared to roughly €151 in fuel and tolls — a saving of about €81. The journey takes 15h 12m versus 8h 38m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 07:10PM | Duration 17h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price €61 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 09:10PM | Duration 17h55 | Departure days Everyday | Cheapest price €61 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 10:10AM | Duration 18h30 | Departure days Everyday | Cheapest price €61 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 10:10AM | Duration 18h15 | Departure days Wed, Fri, Sun | Cheapest price €62 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 06:55AM | Duration 14h40 | Departure days Everyday | Cheapest price €55 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 10:05AM | Duration 17h25 | Departure days Mon, Thu, Sat, Sun | Cheapest price €75 |
Operator BlaBlaCar Bus | Departure Time 05:35PM | Arrival Time 09:45AM | Duration 16h10 | Departure days Mon, Fri | Cheapest price €54 |
Operator RegioJet a.s. | Departure Time 06:30PM | Arrival Time 06:25AM | Duration 11h55 | Departure days Thu, Sun | Cheapest price €60 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 01:30PM | Duration 15h00 | Departure days Everyday | Cheapest price €59 |
The table below shows live departures for Brussels to Prague buses for today, Tuesday, August 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 3:40 PM Brussels, Avenue des Magnolias (King Baudouin) | 18h30 | 10:10 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus | 4:15 PM Brussels, Brussels South (Gare du Midi) | 16h40 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 4:15 PM Brussels, Brussels South (Gare du Midi) | 14h40 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:30 PM Brussels, Brussels South (Gare du Midi) | 17h40 | 4:10 PM Praha, Černý Most | 1 transfer | |
FlixBus | 10:30 PM Brussels, Brussels South (Gare du Midi) | 15h00 | 1:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 1:20 AM Brussels, Brussels South (Gare du Midi) | 17h50 | 7:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:20 AM Brussels, Brussels South (Gare du Midi) | 17h50 | 7:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Brussels, Brussels South (Gare du Midi) | 17h55 | 9:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Brussels, Brussels South (Gare du Midi) | 17h55 | 9:10 PM Praha, Na Knížecí | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brussels to Prague run on average 12 times per day, taking around 15h 12m. Cheap bus tickets for this journey start at €45 but you can travel from only €21 by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 445 miles (717 km) distance in 11h 50m.
Distance 445 miles (717 km) |
Average bus duration 15h 12m |
Cheapest ticket price €45 |
Buses per day 12 |
Direct buses 2 |
Fastest bus 11h 50m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 49 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Brussels to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Brussels to Prague buses use the Brussels, Brussels South (Gare du Midi) to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Na Knížecí. Use this guide to compare Brussels and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
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