- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Oct 10
$68
Average ticket price on Oct 10
$92
Fastest journey on Oct 10
14 h 40 m
Average journey duration on Oct 10
16 h 17 m
Buses on Oct 10
15
Distance
717 km
The best way to find a cheap bus ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Prague will cost around $92 if you buy it on the day, but the cheapest tickets can be found for only $68.
On Sat, Oct 10, we found 15 buses from Brussels to Prague, including 2 direct services.
On Sat, Oct 10 the direct buses cover the 717 km distance in an average of 16 h 17 m but if you time it right, some buses will get you there in just 14 h 40 m .
On Sat, Oct 10 the slowest buses will take 17 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus · FlixBusBuses from Brussels to Prague run on average 10 times per day, taking around 15h 48m. Cheap bus tickets for this journey start at $36 but you can travel from only $15 by train.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 445 miles (717 km) distance in 12h 50m.
Distance 445 miles (717 km) |
Average bus duration 15h 48m |
Cheapest ticket price $36 |
Buses per day 10 |
Direct buses 2 |
Fastest bus 12h 50m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 77 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 07:10PM | Duration 17h50 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 09:10PM | Duration 17h55 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 04:15AM | Arrival Time 10:55PM | Duration 18h40 | Departure days Sat, Sun | Cheapest price $105 |
Operator BlaBlaCar Bus | Departure Time 02:20PM | Arrival Time 09:45AM | Duration 19h25 | Departure days Mon, Fri | Cheapest price $94 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 10:10AM | Duration 18h30 | Departure days Everyday | Cheapest price $50 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 10:10AM | Duration 18h15 | Departure days Wed, Fri, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 08:55AM | Duration 16h40 | Departure days Everyday | Cheapest price $50 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 10:05AM | Duration 17h25 | Departure days Mon, Wed, Thu, Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 12:45PM | Duration 19h05 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $51 |
Operator RegioJet a.s. | Departure Time 06:30PM | Arrival Time 06:25AM | Duration 11h55 | Departure days Thu, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 04:10PM | Duration 17h40 | Departure days Everyday | Cheapest price $51 |
The table below shows live departures for Brussels to Prague buses for today, Friday, October 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
50332 · 30512 | 2:20 PM Brussels, Brussels South (Gare du Midi) | 19h25 | 9:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:40 PM Brussels, Avenue des Magnolias (King Baudouin) | 18h30 | 10:10 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:40 PM Brussels, Avenue des Magnolias (King Baudouin) | 20h20 | 12:00 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 3:55 PM Brussels, Gare Du Midi | 18h15 | 10:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:55 PM Brussels, Gare Du Midi | 19h35 | 11:30 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 4:15 PM Brussels, Brussels South (Gare du Midi) | 16h40 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 4:15 PM Brussels, Brussels South (Gare du Midi) | 14h40 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 4:15 PM Brussels, Brussels South (Gare du Midi) | 19h15 | 11:30 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 5:40 PM Brussels, Brussels South (Gare du Midi) | 19h05 | 12:45 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 10:30 PM Brussels, Brussels South (Gare du Midi) | 17h40 | 4:10 PM Praha, Černý Most | 1 transfer | |
FlixBus | 10:30 PM Brussels, Brussels South (Gare du Midi) | 15h00 | 1:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:30 PM Brussels, Brussels South (Gare du Midi) | 19h05 | 5:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
| Saturday, October 10 | |||||
FlixBus · FlixBus | 1:20 AM Brussels, Brussels South (Gare du Midi) | 17h50 | 7:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:20 AM Brussels, Brussels South (Gare du Midi) | 18h40 | 8:00 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 1:20 AM Brussels, Brussels South (Gare du Midi) | 17h50 | 7:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Brussels, Brussels South (Gare du Midi) | 17h55 | 9:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Brussels, Brussels South (Gare du Midi) | 17h55 | 9:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 4:15 AM Brussels, Brussels South (Gare du Midi) | 18h40 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 4:15 AM Brussels, Brussels South (Gare du Midi) | 18h55 | 11:10 PM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Brussels to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Brussels to Prague buses use the Brussels, Brussels South (Gare du Midi) to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Na Knížecí. Use this guide to compare Brussels and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
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