- Must visit
National Museum
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
Cheapest price
$104
Average price
$134
Fastest journey
14 h 50 m
Average duration
16 h 15 m
Buses per day
15
Distance
860 km
The best way to find a cheap bus ticket from Lyon to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Prague will cost around $134 if you buy it on the day, but the cheapest tickets can be found for only $104.
Of the 15 buses that leave Lyon for Prague on Fri, Jul 10, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 10 the direct buses cover the 860 km distance in an average of 16 h 15 m but if you time it right, some buses will get you there in just 14 h 50 m .
On Fri, Jul 10 the slowest buses will take 17 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus · FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Lyon to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $60. For those with little time consider booking a flight which can get you there in 2h 39m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $60, and a train costs an average of $279.
Distance: 534 miles (860 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$92 Average price Cheapest | $228 Average price | $308 Average price | $264 Average price (fuel + tolls) |
16h 50m Average total duration 16h 20m Onboard + 30m Additional time* | 5h 39m Average total duration Fastest 2h 39m Onboard + 3h 0m Additional time* | 12h 54m Average total duration 12h 24m Onboard + 30m Additional time* | 11h 19m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Prague:
A bus is $136 (€112) less than a flight for this route with tickets for a flight from Lyon to Prague costing on average $228 (€187).
A bus is $216 (€178) less than a train for this route with tickets for a train from Lyon to Prague costing on average $308 (€253).
Other travel options to Prague take longer:
Train takes on average 12h 24m.
Bus takes on average 16h 20m.
Tickets start at around $92 (€76) compared to roughly $264 (€216) in fuel and tolls — a saving of about $172 (€141). The journey takes 16h 20m versus 11h 19m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 09:10PM | Duration 20h50 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $96 |
Operator FlixBus | Departure Time 03:10AM | Arrival Time 09:10PM | Duration 18h00 | Departure days Sat, Sun | Cheapest price $113 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 10:15PM | Duration 18h45 | Departure days Tue, Fri, Sat | Cheapest price $96 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 09:50PM | Duration 16h30 | Departure days Everyday | Cheapest price $96 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 07:50AM | Duration 19h45 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 07:00AM | Duration 17h55 | Departure days Sat, Sun | Cheapest price $155 |
Operator AMI-Tour | Departure Time 01:30PM | Arrival Time 02:00AM | Duration 12h30 | Departure days Mon | Cheapest price $158 |
Operator BlaBlaCar Bus | Departure Time 02:55PM | Arrival Time 09:45AM | Duration 18h50 | Departure days Mon, Fri | Cheapest price $104 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 11:20AM | Duration 17h15 | Departure days Everyday | Cheapest price $96 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 02:45PM | Duration 17h15 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 04:10PM | Duration 18h10 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 07:20PM | Duration 20h20 | Departure days Fri | Cheapest price $175 |
The table below shows live departures for Lyon to Prague buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h15 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h15 | 9:20 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h50 | 8:55 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h15 | 2:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h05 | 2:35 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 18h10 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h25 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
| Friday, July 10 | |||||
FlixBus · FlixBus · FlixBus | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h50 | 9:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 3:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 18h45 | 10:15 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h30 | 9:50 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h35 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h25 | 12:45 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h45 | 7:50 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h25 | 8:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h25 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lyon to Prague run on average 12 times per day, taking around 16h 20m. Cheap bus tickets for this journey start at $60 (€49) but you can travel from only $55 (€46) by flight.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 534 miles (860 km) distance in 15h 5m.
Distance 534 miles (860 km) |
Average bus duration 16h 20m |
Cheapest ticket price $60 (€49) |
Buses per day 12 |
Direct buses 6 |
Fastest bus 15h 5m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 49 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
One of Prague’s most significant museum institutions, preserving Jewish history through synagogues, exhibitions, and the Old Jewish Cemetery.
A leading city gallery in a Gothic landmark on Old Town Square, hosting major modern and contemporary art exhibitions.
Prague’s historic heart, surrounded by major monuments and lively at all times of day; essential for first-time visitors.
A picturesque Baroque district below Prague Castle with quiet lanes, embassies, gardens, and classic city charm.
A major boulevard-like square central to modern Czech history, shopping, and the city’s urban energy.
Marinated beef sirloin with a creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the most iconic Czech Sunday and festive dishes.
Roast pork served with bread dumplings and braised sauerkraut. This is a classic Czech pub and home-style meal strongly associated with Bohemian cooking.
Czech goulash is a rich beef stew seasoned with onion and paprika, usually served with bread dumplings. It is a staple of traditional Prague taverns and beer halls.
A Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients, tasting menus, and a sophisticated modern atmosphere.
An elegant grand café offering refined Czech and Central European dishes, excellent breakfasts, and classic pastries in a beautifully restored interior.
A well-regarded Old Town restaurant focused on updated Czech cuisine, including svíčková and goulash, in a polished but approachable setting.
Moderate for Europe: beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip is expected for fast food, but small change is appreciated in cafés.
Official public transport app
Prague Main Railway Station -> Old Town Square, Prague
Find answers to the most common questions about traveling from Lyon to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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