Lyon to Prague bus with FlixBus

Sun, Feb 22
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FlixBus
BlaBlaCar Bus
Costa Verde
Alsa
Rede Expressos
1,000+ travel companies
FlixBus
BlaBlaCar Bus
Costa Verde
Alsa
Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Lyon to Prague

Showing times and prices for Feb 24

Cheapest price

$73

Average price

$99

Fastest journey

16 h 30 m

Average duration

17 h 4 m

Buses per day

13

Distance

860 km

Cheap tickets

The best way to find a cheap bus ticket from Lyon to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Lyon to Prague will cost around $99 if you buy it on the day, but the cheapest tickets can be found for only $73.

Fast buses

Of the 13 buses that leave Lyon for Prague on Tue, Feb 24, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Feb 24 the direct buses cover the 860 km distance in an average of 17 h 4 m but if you time it right, some buses will get you there in just 16 h 30 m .

On Tue, Feb 24 the slowest buses will take 17 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

BlaBlaCar Bus30506
03:05AM16h55
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
08:00PMPraha, ÚAN Florenc
$731One-way
0 transfers
FlixBusFlixBus
09:30PM17h05
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
02:35PMPrague, Central Train Station
$881One-way
0 transfers
FlixBusFlixBus
09:30PM17h15
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
02:45PMPraha, ÚAN Florenc
$881One-way
0 transfers
FlixBusFlixBus
05:20AM16h30
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
09:50PMPraha, ÚAN Florenc
$971One-way
0 transfers
FlixBusFlixBus · FlixBus
09:30PM22h50
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
08:20PMPraha, Na Knížecí
$971One-way
1 transfer

Travel Information

Compare bus, train, and flight for Lyon to Prague

Omio recommends booking the flight as it is the most popular option from Lyon to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €47. For those with little time consider booking a flight which can get you there in 2h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of €47, and a train costs an average of €226.

Distance: 534 miles (860 km)

Compare bus with

Bus
Most popular
Flight
Train

€70

Average price

Cheapest

€155

Average price

€254

Average price

16h 49m

Average total duration

16h 19m

Onboard

+

30m

Additional time*

5h 38m

Average total duration

Fastest

2h 38m

Onboard

+

3h 0m

Additional time*

12h 54m

Average total duration

12h 24m

Onboard

+

30m

Additional time*

0.9 - 2.1kg

CO2 emissions

Lowest

2.6 - 5.2kg

CO2 emissions

-

CO2 emissions

FlixBus

Most popular bus company

Volotea

Most popular airline

TGV

Most popular train company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Lyon to Prague Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
02:25AM
Arrival Time
02:50AM
Duration
24h25
Departure days
Wed, Thu
Cheapest price
$70
Operator
BlaBlaCar Bus
Departure Time
03:05AM
Arrival Time
08:00PM
Duration
16h55
Departure days
Tue, Fri, Sat
Cheapest price
$67
Operator
FlixBus
Departure Time
03:30AM
Arrival Time
10:15PM
Duration
18h45
Departure days
Tue, Fri, Sat
Cheapest price
$77
Operator
FlixBus
Departure Time
05:20AM
Arrival Time
09:50PM
Duration
16h30
Departure days
Tue, Fri, Sat, Sun
Cheapest price
$72
Operator
FlixBus
Departure Time
08:35AM
Arrival Time
11:30AM
Duration
26h55
Departure days
Wed
Cheapest price
$74
Operator
FlixBus
Departure Time
09:00AM
Arrival Time
06:00AM
Duration
21h00
Departure days
Fri, Sat, Sun
Cheapest price
$78
Operator
BlaBlaCar Bus
Departure Time
12:00PM
Arrival Time
09:45AM
Duration
21h45
Departure days
Fri
Cheapest price
$95
Operator
FlixBus
Departure Time
12:15PM
Arrival Time
08:30AM
Duration
20h15
Departure days
Fri, Sat, Sun
Cheapest price
$76
Operator
FlixBus
Departure Time
12:45PM
Arrival Time
10:35AM
Duration
21h50
Departure days
Tue, Wed
Cheapest price
$73
Operator
FlixBus
Departure Time
01:05PM
Arrival Time
09:20AM
Duration
20h15
Departure days
Tue, Wed
Cheapest price
$73
Operator
Regiojet
Departure Time
02:35PM
Arrival Time
06:25AM
Duration
15h50
Departure days
Sat
Cheapest price
$87
Operator
FlixBus
Departure Time
06:15PM
Arrival Time
09:20AM
Duration
15h05
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$72
Operator
FlixBus
Departure Time
09:25PM
Arrival Time
10:55PM
Duration
25h30
Departure days
Wed
Cheapest price
$82
Operator
FlixBus
Departure Time
09:30PM
Arrival Time
02:35PM
Duration
17h05
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
$72
Operator
FlixBus
Departure Time
10:00PM
Arrival Time
04:10PM
Duration
18h10
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$72

Live departures

Lyon to Prague bus times

The table below shows live departures for Lyon to Prague buses for today, Monday, February 23. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:50 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus5:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
15h05
8:20 AM Praha, ÚAN Florenc0 transfersDirect
meinfernbus_flixbusFlixBus5:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
14h40
7:55 AM Praha, Na Knížecí0 transfersDirect
meinfernbus_flixbusFlixBus8:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
17h05
1:35 PM Prague, Central Train Station0 transfersDirect
meinfernbus_flixbusFlixBus8:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
17h15
1:45 PM Praha, ÚAN Florenc0 transfersDirect
meinfernbus_flixbusFlixBus9:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
18h10
3:10 PM Praha, Černý Most0 transfersDirect
meinfernbus_flixbusFlixBus9:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
17h25
2:25 PM Praha, ÚAN Florenc0 transfersDirect
Tuesday, February 24
blablacarbus305062:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
16h55
7:00 PM Praha, ÚAN Florenc0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus2:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
18h45
9:15 PM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
16h30
8:50 PM Praha, ÚAN Florenc0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
17h35
9:55 PM Praha, Na Knížecí1 transfer
meinfernbus_flixbusFlixBus · FlixBus4:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
19h05
11:25 PM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus11:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
21h50
9:35 AM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus11:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
22h45
10:30 AM Praha, Zličín2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
23h40
11:45 AM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
23h35
11:40 AM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
20h15
8:20 AM Praha, ÚAN Florenc1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Lyon to Prague by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Lyon to Prague buses with Omio?

FlixBus as well as BlaBlaCar Bus offer buses services from Lyon to Prague.
Omio is an official ticket reseller for all your travel options from Lyon to Prague.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Lyon to Prague.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Lyon to Prague.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Lyon to Prague.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Lyon to Prague.

Journey information

Overview: Bus from Lyon to Prague

FranceFrance
CzechiaCzechia
Icon of bus

Buses from Lyon to Prague run on average 12 times per day, taking around 16h 19m. Cheap bus tickets for this journey start at $60 (€47) but you can travel from only $55 (€44) by flight.

There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 534 miles (860 km) distance in 12h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $55 (€44)
Distance
534 miles (860 km)
Average bus duration
16h 19m
Cheapest ticket price
$60 (€47)
Buses per day
12
Direct buses
6
Fastest bus
12h 30m
First bus
00:10
Last bus
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $55 (€44)

Bus providers: FlixBus, BlaBlaCar Bus from Lyon to PragueYou can travel by bus between Lyon to Prague with FlixBus, BlaBlaCar Bus for as low as $55 (€44). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 40m
Cheapest Price
$60 (€47)
FlixBus frequency
13 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

BlaBlaCar Bus

About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
16h 55m
Cheapest Price
$60 (€48)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.

FAQs: Bus from Lyon to Prague

Find answers to the most common questions about traveling from Lyon to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Lyon to Prague can start from as little as $60 (€47) when you book in advance. The average bus ticket price for Lyon to Prague is $88 (€70) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Lyon to Prague is 12h 30m to travel the 534 miles (860 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Lyon to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Lyon to Prague leaves at 11:50 PM.
Yes, there are 6 direct buses a day from Lyon to Prague with FlixBus, BlaBlaCar Bus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Lyon to Prague, you can count on FlixBus, BlaBlaCar Bus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Lyon and Prague and compare the amenities they offer before buying a bus ticket.
When departing from Lyon , you have various bus station options to start your journey from including Lyon, Perrache Bus Station, Lyon, St Exupéry Aéroport, Givors, Plaza Jean Berry, Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan), Lyon, Gare Perrache . When arriving in Prague , you can end your journey in bus stations like Praha, ÚAN Florenc, Prague, Central Train Station, Praha, Na Knížecí, Praha, Černý Most, Praha, Zličín, Praha, Letiště Václava Havla, Praha, Roztyly, Praha, M. Horákové (Hradčanská) .Passengers board the bus most frequently from Lyon, Perrache Bus Station, which is located around 1 away from the city centre, and they get off the bus at Praha, ÚAN Florenc, located 1 away from the city centre.
A trip to Prague from Lyon is worth doing but not as a day trip with a journey time of 12h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Lyon to Prague is April.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Prague including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Lyon to Prague:
  • BlaBlaCar Bus
    • Assistance
    • Priority boarding
    • Accessible seating options.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Lyon to Prague for bus company FlixBus, BlaBlaCar Bus.
Some of the most interesting sights to explore in Prague are:
  • Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
  • Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
  • Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
  • St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
  • The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
  • Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
  • Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
  • Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
  • Visit the National Museum to delve into Czech history and culture
  • Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Lyon to Prague depends on the bus companies:
  • BlaBlaCar Bus
    • You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Lyon to Prague.
Yes, the following luggage options are included when booking a bus ticket from Lyon to Prague:
  • BlaBlaCar Bus
    • One carry-on bag up to 7kg and one checked bag up to 20kg.
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Lyon to Prague:
  • BlaBlaCar Bus
    • Additional luggage can be purchased for a fee.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Lyon to Prague. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Lyon to Prague with the following bus company: FlixBus, BlaBlaCar Bus
Yes, there are USB plugs on board the bus from Lyon to Prague with the following bus company: FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the bus from Lyon to Prague with the following bus company: FlixBus, BlaBlaCar Bus.

popular bus stations

Popular bus stations from Lyon to Prague

Lyon
Prague
The major bus station for departures in Lyon is Lyon, Gare Routière de Perrache. Find all the information you need to know about services, amenities and connections at Lyon, Gare Routière de Perrache for your trip from Lyon to Prague.
Lyon, Gare Routière de PerracheWifiParkingDiningATMTaxisAccessibilityWCTicket Office
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
information
ticketOfficeHours
Ticket Office Hours
  • 06:00-23:00
ticketOfficeHours
Distance to city center
1 km
carConnection
Car connection
Cours de Verdun
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • Café de la Gare (in the station)
  • Le Bistrot de Lyon (0.5 km)
  • Brasserie Georges (0.6 km).
Taxis
Taxis
  • Available outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available in the station.
Public transit options for Lyon, Gare Routière de Perrache
  • Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Lyon, St Exupéry Aéroport
information
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)
information

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