- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Oct 08
$79
Average ticket price on Oct 08
$100
Fastest journey on Oct 08
14 h 50 m
Average journey duration on Oct 08
16 h 22 m
Buses on Oct 08
8
Distance
860 km
The best way to find a cheap bus ticket from Lyon to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Prague will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $79.
On Thu, Oct 08, we found 8 buses from Lyon to Prague, including 6 direct services.
On Thu, Oct 08 the direct buses cover the 860 km distance in an average of 16 h 22 m but if you time it right, some buses will get you there in just 14 h 50 m .
On Thu, Oct 08 the slowest buses will take 17 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus
FlixBusBuses from Lyon to Prague run on average 13 times per day, taking around 16h 43m. Cheap bus tickets for this journey start at $49 (€41) but you can travel from only $25 (€21) by flight.
There are 7 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 534 miles (860 km) distance in 12h 30m.
Distance 534 miles (860 km) |
Average bus duration 16h 43m |
Cheapest ticket price $49 (€41) |
Buses per day 13 |
Direct buses 7 |
Fastest bus 12h 30m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Tue |
Best time to book 77 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:20AM | Arrival Time 10:55PM | Duration 20h35 | Departure days Wed, Thu | Cheapest price $117 |
Operator FlixBus | Departure Time 03:10AM | Arrival Time 09:10PM | Duration 18h00 | Departure days Sat, Sun | Cheapest price $89 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 10:15PM | Duration 18h45 | Departure days Tue, Fri, Sat | Cheapest price $71 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 10:55PM | Duration 17h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 06:55AM | Duration 23h25 | Departure days Wed | Cheapest price $107 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 07:30AM | Duration 22h30 | Departure days Wed | Cheapest price $92 |
Operator BlaBlaCar Bus | Departure Time 12:00PM | Arrival Time 09:45AM | Duration 21h45 | Departure days Mon, Fri | Cheapest price $85 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 07:30AM | Duration 19h25 | Departure days Mon, Fri, Sat, Sun | Cheapest price $63 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 11:30AM | Duration 22h45 | Departure days Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 07:00AM | Duration 17h55 | Departure days Wed, Sat, Sun | Cheapest price $84 |
Operator AMI-Tour | Departure Time 01:30PM | Arrival Time 02:00AM | Duration 12h30 | Departure days Mon | Cheapest price $155 |
Operator RegioJet a.s. | Departure Time 02:35PM | Arrival Time 06:30AM | Duration 15h55 | Departure days Sat | Cheapest price $95 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 05:35PM | Duration 23h55 | Departure days Wed | Cheapest price $100 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 08:55AM | Duration 14h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $66 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 02:35PM | Duration 17h05 | Departure days Everyday | Cheapest price $68 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 03:25PM | Duration 17h25 | Departure days Everyday | Cheapest price $66 |
Operator FlixBus | Departure Time 10:15PM | Arrival Time 09:10PM | Duration 22h55 | Departure days Wed | Cheapest price $81 |
The table below shows live departures for Lyon to Prague buses for today, Wednesday, October 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 22h50 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h15 | 2:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h05 | 2:35 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h25 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 18h10 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus · FlixBus | 10:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 22h55 | 9:10 PM Praha, Na Knížecí | 1 transfer | |
| Thursday, October 8 | |||||
FlixBus · FlixBus | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h35 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h10 | 9:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h50 | 8:55 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h15 | 9:20 AM Praha, ÚAN Florenc | 0 transfersDirect | |
Find all the dates and times for this journey
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Lyon to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Lyon to Prague buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Lyon and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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