The cheapest and fastest buses from Lyon to Prague
Cheapest price
$82
Average price
$86
Fastest journey
14 h 40 m
Average duration
15 h 49 m
Buses per day
14
Distance
860 km
The best way to find a cheap bus ticket from Lyon to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Prague will cost around $86 if you buy it on the day, but the cheapest tickets can be found for only $82.
Of the 14 buses that leave Lyon for Prague on Sat, Jan 10, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jan 10 the direct buses cover the 860 km distance in an average of 15 h 49 m but if you time it right, some buses will get you there in just 14 h 40 m .
On Sat, Jan 10 the slowest buses will take 16 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
FlixBus · FlixBus
(Lyon -> Prague)
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus
(Lyon -> Prague)
FlixBus
FlixBusTravel Information
Compare bus, train, and flight for Lyon to Prague
Omio recommends booking the flight as it is the most popular option from Lyon to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €48. For those with little time consider booking a flight which can get you there in 2h 40m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of €48, and a train costs an average of €226.
Distance: 534 miles (860 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€73 Average price Cheapest | €176 Average price | €232 Average price |
17h 14m Average total duration 16h 44m Onboard + 30m Additional time* | 5h 40m Average total duration Fastest 2h 40m Onboard + 3h 0m Additional time* | 12h 54m Average total duration 12h 24m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Lyon to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:20AM | Arrival Time 10:50PM | Duration 20h30 | Departure days Thu | Cheapest price $67 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 10:15PM | Duration 19h00 | Departure days Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 10:15PM | Duration 18h45 | Departure days Fri, Sat | Cheapest price $84 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 10:55PM | Duration 17h35 | Departure days Mon, Fri, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 06:00AM | Duration 20h30 | Departure days Mon, Fri, Sat, Sun | Cheapest price $65 |
Operator Infobus | Departure Time 01:30PM | Arrival Time 02:00AM | Duration 12h30 | Departure days Mon | Cheapest price $171 |
Operator Regiojet | Departure Time 02:35PM | Arrival Time 06:30AM | Duration 15h55 | Departure days Sat | Cheapest price $82 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 10:50AM | Duration 17h45 | Departure days Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 09:20AM | Duration 15h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 02:05PM | Duration 17h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 04:10PM | Duration 18h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $65 |
Live departures
Lyon to Prague bus times
The table below shows live departures for Lyon to Prague buses for today, Friday, January 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:30 AM Lyon, Perrache Bus Station | 20h45 | 5:15 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 8:30 AM Lyon, Perrache Bus Station | 20h30 | 5:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:05 PM Lyon, Perrache Bus Station | 17h45 | 9:50 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 5:15 PM Lyon, Perrache Bus Station | 14h40 | 7:55 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 5:15 PM Lyon, Perrache Bus Station | 15h05 | 8:20 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 8:00 PM Lyon, Perrache Bus Station | 16h55 | 12:55 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 8:00 PM Lyon, Perrache Bus Station | 17h05 | 1:05 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 PM Lyon, Perrache Bus Station | 17h25 | 2:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 PM Lyon, Perrache Bus Station | 18h10 | 3:10 PM Praha, Černý Most | 0 transfersDirect | |
| Saturday, January 10 | |||||
FlixBus · FlixBus | 2:30 AM Lyon, Perrache Bus Station | 18h45 | 9:15 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:20 AM Lyon, Perrache Bus Station | 19h05 | 11:25 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:20 AM Lyon, Perrache Bus Station | 17h35 | 9:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 4:20 AM Lyon, Perrache Bus Station | 16h30 | 8:50 PM Praha, ÚAN Florenc | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Lyon to Prague
Buses from Lyon to Prague run on average 11 times per day, taking around 16h 44m. Cheap bus tickets for this journey start at $60 (€48) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 534 miles (860 km) distance in 14h 40m.
Distance 534 miles (860 km) |
Average bus duration 16h 44m |
Cheapest ticket price $60 (€48) |
Buses per day 11 |
Direct buses 5 |
Fastest bus 14h 40m |
First bus 00:10 |
Last bus 23:50 |
Bus providers: FlixBus, BlaBlaCar Bus from Lyon to PragueYou can travel by bus between Lyon to Prague with FlixBus, BlaBlaCar Bus for as low as $60 (€48). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
FAQs: Bus from Lyon to Prague
Find answers to the most common questions about traveling from Lyon to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Lyon, Perrache Bus Station, which is located around 1.4 miles (2.3 km) away from the city centre, and they get off the bus at Prague, Central Train Station, located 1.8 miles (2.9 km) away from the city centre.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
To find the cheapest bus tickets for your trip from Lyon to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Lyon to Prague
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Lyon
More options for your journey from Lyon to Prague
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