- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
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The cheapest and fastest buses from Lyon to Prague
Showing times and prices for Aug 24
Cheapest price
$98
Average price
$116
Fastest journey
12 h 30 m
Average duration
15 h 14 m
Buses per day
16
Distance
860 km
Cheap tickets
The best way to find a cheap bus ticket from Lyon to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Prague will cost around $116 if you buy it on the day, but the cheapest tickets can be found for only $98.
Fast buses
Of the 16 buses that leave Lyon for Prague on Mon, Aug 24, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Aug 24 the direct buses cover the 860 km distance in an average of 15 h 14 m but if you time it right, some buses will get you there in just 12 h 30 m .
On Mon, Aug 24 the slowest buses will take 17 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus6:05 PM15h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:20 AMPraha, ÚAN Florenc$981One-way0 transfers- FlixBus6:05 PM14h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:55 AMPraha, Na Knížecí$981One-way0 transfers
- FlixBus5:20 AM16h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:50 PMPraha, ÚAN Florenc$1021One-way0 transfers
- FlixBus · FlixBus · FlixBus12:05 PM20h25Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:30 AMPraha, Zličín$1031One-way2 transfers
- FlixBus · FlixBus6:05 PM17h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:20 AMPrague, Central Train Station$1041One-way1 transfer
69106461:30 PM12h30Lyon2:00 AMPrague$1621One-way0 transfers- FlixBus6:05 PM14h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:55 AMPraha, Na Knížecí$981One-way0 transfers
- FlixBus6:05 PM15h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:20 AMPraha, ÚAN Florenc$981One-way0 transfers
- FlixBus5:20 AM16h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:50 PMPraha, ÚAN Florenc$1021One-way0 transfers
- FlixBus9:30 PM17h05Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)2:35 PMPrague, Central Train Station$1111One-way0 transfers
Travel Information
Compare bus, flight, and train for Lyon to Prague
Omio recommends booking the bus as it is the most popular option from Lyon to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $61. For those with little time consider booking a flight which can get you there in 2h 39m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $61, and a train costs an average of $284.
Distance: 534 miles (860 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$94 Average price Cheapest | $233 Average price | $315 Average price | $272 Average price (fuel + tolls) |
16h 50m Average total duration 16h 20m Onboard + 30m Additional time* | 5h 39m Average total duration Fastest 2h 39m Onboard + 3h 0m Additional time* | 12h 54m Average total duration 12h 24m Onboard + 30m Additional time* | 11h 19m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | 2.6 - 5.2kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Lyon to Prague is a bus with an average price of $94 (€76).
This is compared to other travel options from Lyon to Prague:
A bus is $139 (€112) less than a flight for this route with tickets for a flight from Lyon to Prague costing on average $233 (€187).
A bus is $221 (€178) less than a train for this route with tickets for a train from Lyon to Prague costing on average $315 (€253).
The fastest way to travel from Lyon to Prague is by flight with an average journey time of 2h 39m.
Other travel options to Prague take longer:
Train takes on average 12h 24m.
Bus takes on average 16h 20m.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Prague including taking a bus, flight, and train.
We recommend using the bus as it is the most popular way to get from Lyon to Prague among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $94 (€76) compared to roughly $269 (€216) in fuel and tolls — a saving of about $175 (€141). The journey takes 16h 20m versus 11h 19m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Lyon to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 09:10PM | Duration 20h50 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $100 |
Operator FlixBus | Departure Time 03:10AM | Arrival Time 11:55PM | Duration 20h45 | Departure days Sat, Sun | Cheapest price $118 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 10:15PM | Duration 18h45 | Departure days Tue, Fri, Sat | Cheapest price $94 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 10:55PM | Duration 17h35 | Departure days Everyday | Cheapest price $93 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 07:30AM | Duration 19h25 | Departure days Everyday | Cheapest price $95 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 07:10AM | Duration 18h05 | Departure days Sat, Sun | Cheapest price $126 |
Operator AMI-Tour | Departure Time 01:30PM | Arrival Time 02:00AM | Duration 12h30 | Departure days Mon | Cheapest price $162 |
Operator RegioJet a.s. | Departure Time 02:35PM | Arrival Time 06:30AM | Duration 15h55 | Departure days Sat | Cheapest price $87 |
Operator BlaBlaCar Bus | Departure Time 02:55PM | Arrival Time 09:45AM | Duration 18h50 | Departure days Mon, Fri | Cheapest price $124 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 11:20AM | Duration 17h15 | Departure days Everyday | Cheapest price $87 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 02:45PM | Duration 17h15 | Departure days Everyday | Cheapest price $90 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 04:10PM | Duration 18h10 | Departure days Everyday | Cheapest price $87 |
Live departures
Lyon to Prague bus times
The table below shows live departures for Lyon to Prague buses for today, Sunday, August 23. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h15 | 11:20 AM Prague, Central Train Station | 1 transfer | |
| FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h50 | 8:55 AM Praha, Na Knížecí | 0 transfersDirect | |
| FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h15 | 9:20 AM Praha, ÚAN Florenc | 0 transfersDirect | |
| FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h05 | 2:35 PM Prague, Central Train Station | 0 transfersDirect | |
| FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h15 | 2:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
| FlixBus | 10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 18h10 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
| FlixBus | 10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h25 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
| Monday, August 24 | |||||
| FlixBus · FlixBus · FlixBus | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h50 | 9:10 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 17h35 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
| FlixBus | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 16h30 | 9:50 PM Praha, ÚAN Florenc | 0 transfersDirect | |
| FlixBus · FlixBus | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h25 | 12:45 AM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus | 12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h25 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h25 | 8:30 AM Praha, Zličín | 2 transfers | |
| FlixBus · FlixBus | 12:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h45 | 7:50 AM Praha, ÚAN Florenc | 1 transfer | |
| 6910646 | 1:30 PM Lyon | 12h30 | 2:00 AM Prague | 0 transfersDirect | |
 7664 · 30512 | 2:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 18h50 | 9:45 AM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Prague by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Lyon to Prague buses with Omio?
FlixBus as well as BlaBlaCar Bus offer buses services from Lyon to Prague.
Omio is an official ticket reseller for all your travel options from Lyon to Prague.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Lyon to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Lyon to Prague.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Lyon to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Lyon to Prague.
Journey information
Overview: Bus from Lyon to Prague
France
Czechia
Buses from Lyon to Prague run on average 13 times per day, taking around 16h 21m. Cheap bus tickets for this journey start at $60 (€48) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 534 miles (860 km) distance in 15h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 534 miles (860 km) |
Average bus duration 16h 21m |
Cheapest ticket price $60 (€48) |
Buses per day 13 |
Direct buses 6 |
Fastest bus 15h 15m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 49 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, BlaBlaCar Bus from Lyon to PragueYou can travel by bus between Lyon to Prague with FlixBus, BlaBlaCar Bus for as low as $57 (€46). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
15h 15m
Cheapest Price
$60 (€48)
FlixBus frequency
13 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
16h 55m
Cheapest Price
$66 (€53)
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
Complete guide to Prague
Things to do in Prague
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
- Must visit
Jewish Museum in Prague
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
- Recommended
National Gallery Prague – Schwarzenberg Palace
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
- Must visit
Old Town Square
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
- Must visit
Wenceslas Square
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
- Must visit
Malá Strana
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Svíčková na smetaně
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
- Gluten-free
Pečené vepřové koleno
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Vepřo knedlo zelo
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
U Kroka
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Mlýnec
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
La Degustation Bohême Bourgeoise
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Czech koruna (Kč)
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Average meal costs
- Budget
- Kč150-Kč250 for fast food or street food.
- Mid-range
- Kč300-Kč600 per person for a meal.
- Fine dining
- Kč1,200+ per person for upscale restaurants.
- Coffee
- Kč55-Kč85 for cappuccino.
Tipping culture
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
PID Lítačka
Get the appOfficial public transport app
Prices
- Single ticket
- 40 Kč
- Day pass
- 120 Kč
To the city center
Prague Central Train Station -> Wenceslas Square
- Distance
- 1 km
- Travel time
- 6 min
- Contactless card payment works in the PID Lítačka app and at many ticket machines; validate paper tickets before boarding.
- A 24-hour ticket covers metro, trams, buses, and ferries in Prague under PID.
FAQs: Bus from Lyon to Prague
Find answers to the most common questions about traveling from Lyon to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Lyon to Prague can start from as little as $61 (€49) when you book in advance. The average bus ticket price for Lyon to Prague is $94 (€76) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Lyon to Prague is 15h 5m to travel the 534 miles (860 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Lyon to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Lyon to Prague leaves at 11:50 PM.
Yes, there are 6 direct buses a day from Lyon to Prague with FlixBus, BlaBlaCar Bus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Lyon to Prague, you can count on FlixBus, BlaBlaCar Bus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Lyon and Prague and compare the amenities they offer before buying a bus ticket.
When departing from Lyon , you have various bus station options to start your journey from including Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), Lyon, Perrache Bus Station, Lyon, St Exupéry Aéroport, Lyon, Gare Perrache, Lyon, Givors, Plaza Jean Berry . When arriving in Prague , you can end your journey in bus stations like Praha, ÚAN Florenc, Prague, Central Train Station, Praha, Na Knížecí, Praha, Černý Most, Praha, Zličín, Praha, M. Horákové (Hradčanská), Praha, Letiště Václava Havla, Praha, Roztyly .Passengers board the bus most frequently from Lyon, Perrache Bus Station, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Praha, ÚAN Florenc, located 1 away from the city centre.
A trip to Prague from Lyon is worth doing but not as a day trip with a journey time of 15h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Lyon to Prague is May.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Prague including taking a bus, flight, and train.
Yes, the following accessibility options are available when taking the bus from Lyon to Prague:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Lyon to Prague for bus company FlixBus, BlaBlaCar Bus.
Some of the most interesting sights to explore in Prague are:
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Lyon to Prague depends on the bus companies:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Lyon to Prague.
Yes, the following luggage options are included when booking a bus ticket from Lyon to Prague:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Lyon to Prague:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Lyon to Prague. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Lyon to Prague with the following bus company: FlixBus, BlaBlaCar Bus
Yes, there are USB plugs on board the bus from Lyon to Prague with the following bus company: FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the bus from Lyon to Prague with the following bus company: FlixBus, BlaBlaCar Bus.
Since both Lyon and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Lyon to Prague among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Lyon to Prague
Most Lyon to Prague buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Lyon and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Lyon
Arrival bus stations in Prague
Which Lyon station do buses to Prague leave from?
Buses from Lyon to Prague leave from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). The station is 1 miles (3 km) from Lyon city centre at 52 Av. Tony Garnier, 69007 Lyon, France.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)52 Av. Tony Garnier, 69007 Lyon, France
City-centre transport
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
BusN734 · 15m · $1
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Tickets and information
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Parking, taxis and toilets
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache13 Cours de Verdun, 69002 Lyon, France
City-centre transport
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
TrainTer · 5m · $1 · every ~5 min
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry AéroportLyon St Exupéry Aéroport, 69125 Colombier-Saugnieu, France
City-centre transport
Getting to Lyon, St Exupéry Aéroport from Lyon city centre
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
TrainRx · 29m · $20 · every ~8 min
BusS766, 776, 787, N760, N1759, 1776, 1624, N746, 1779, S1736, 1606, 1787, 1676 · 38m · $2 · every ~1 min
Lyon, St Exupéry Aéroport bus station facilities and services
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Tickets and information
Ticket office support is available at Lyon, St Exupéry Aéroport.
Parking, taxis and toilets
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Which Prague station do buses from Lyon arrive at?
Buses from Lyon to Prague most often arrive at Praha, ÚAN Florenc. Some services arrive at Praha, Hlavní Nádraží, so check your ticket before travel to confirm your Prague arrival station.
Praha, ÚAN FlorencKrizikova 6, 186 00 Praha 8-Karlin, Czechia
City-centre transport
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Bus207, *888 · 9m · $2 · every ~14 min
Tram3, 24, 31, 92, 94 · 13m · $2 · every ~24 min
SubwayB · 2m · $2 · every ~27 min
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní NádražíWilsonova 300/8, 110 00 Praha 1, Czech Republic
City-centre transport
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · $1 · every ~3 min
Nj · 8m · $17
Bus478 · 5m
Tram17, 93 · 10m · $2 · every ~23 min
17, 93 · 12m · $2 · every ~23 min
SubwayC · 5m · $2 · every ~29 min
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na KnížecíNa Knizeci, Prague, Czech Republic
City-centre transport
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Bus907, 908 · 16m · $2 · every ~1 min
N109, 084, N1759, N1309, 853, 109 · 20m · $1 · every ~1 min
Tram12, 15, 20 · 11m · $2 · every ~33 min
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Most popular bus connections from Lyon
More options for your journey from Lyon to Prague
Here are some other resources that might have the information you need
Most popular buses to and from Prague and Lyon
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