- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
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The cheapest and fastest buses from Rome to Prague
Showing times and prices for Aug 29
Cheapest price
RM128
Average price
RM164
Fastest journey
19 h 55 m
Average duration
20 h 15 m
Buses per day
43
Distance
923 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around RM164 if you buy it on the day, but the cheapest tickets can be found for only RM128.
Fast buses
Of the 43 buses that leave Rome for Prague on Sat, Aug 29, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Aug 29 the direct buses cover the 923 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 19 h 55 m .
On Sat, Aug 29 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus5:05 PM20h50Roma, Autostazione Tiburtina1:55 PMPraha, ÚAN FlorencRM1281One-way0 transfers- FlixBus5:05 PM20h40Roma, Autostazione Tiburtina1:45 PMPrague, Central Train StationRM1281One-way0 transfers
- FlixBus · FlixBus · FlixBus12:20 PM25h00Roma, Autostazione Tiburtina1:20 PMPraha, RoztylyRM1291One-way2 transfers
- FlixBus · FlixBus9:00 PM20h45Roma, Autostazione Tiburtina5:45 PMPraha, ÚAN FlorencRM1401One-way1 transfer
- FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train StationRM1401One-way1 transfer
- FlixBus · FlixBus · FlixBus5:25 PM19h55Roma, Autostazione (Metro Anagnina)1:20 PMPrague, Central Train StationRM1571One-way2 transfers
- FlixBus · FlixBus · FlixBus5:25 PM20h05Roma, Autostazione (Metro Anagnina)1:30 PMPraha, ÚAN FlorencRM1571One-way2 transfers
- FlixBus · FlixBus1:05 PM20h20Roma, Autostazione (Metro Anagnina)9:25 AMPraha, ÚAN FlorencRM1751One-way1 transfer
- FlixBus · FlixBus10:55 PM20h25Roma, Autostazione Tiburtina7:20 PMPrague, Central Train StationRM1551One-way1 transfer
- FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train StationRM1401One-way1 transfer
Travel Information
Compare train, bus, and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the flight with prices starting from RM15. For those with little time consider booking a flight which can get you there in 2h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of RM15, and a train costs an average of RM236.
Distance: 573 miles (923 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
RM97 Average price | RM77 Average price Cheapest | RM239 Average price | RM291 Average price (fuel + tolls) |
20h 27m Average total duration 19h 57m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 2h 50m Onboard + 2h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* | 13h 23m Average total duration (door-to-door) |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Rome to Prague is a flight with an average price of RM77.
This is compared to other travel options from Rome to Prague:
A flight is RM20 less than a bus for this route with tickets for a bus from Rome to Prague costing on average RM97.
A flight is RM162 less than a train for this route with tickets for a train from Rome to Prague costing on average RM239.
The fastest way to travel from Rome to Prague is by flight with an average journey time of 2h 50m.
Other travel options to Prague take longer:
Train takes on average 17h 32m.
Bus takes on average 19h 57m.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Rome to Prague among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around RM97 compared to roughly RM291 in fuel and tolls — a saving of about RM194. The journey takes 19h 57m versus 13h 23m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Rome to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:45AM | Duration 22h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price RM94 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 07:10AM | Duration 21h40 | Departure days Everyday | Cheapest price RM86 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 11:30AM | Duration 24h50 | Departure days Everyday | Cheapest price RM95 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 10:35AM | Duration 22h55 | Departure days Fri | Cheapest price RM175 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 12:45PM | Duration 24h45 | Departure days Everyday | Cheapest price RM88 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 10:35AM | Duration 22h25 | Departure days Everyday | Cheapest price RM93 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 12:45PM | Duration 24h25 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price RM91 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:20PM | Duration 24h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price RM87 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 09:10AM | Duration 20h10 | Departure days Wed, Sun | Cheapest price RM64 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 01:30PM | Duration 24h25 | Departure days Everyday | Cheapest price RM87 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 05:35PM | Duration 24h35 | Departure days Everyday | Cheapest price RM88 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 01:45PM | Duration 20h40 | Departure days Everyday | Cheapest price RM91 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 01:30PM | Duration 20h05 | Departure days Everyday | Cheapest price RM88 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 08:20PM | Duration 23h20 | Departure days Everyday | Cheapest price RM87 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 08:15PM | Duration 22h55 | Departure days Mon, Tue | Cheapest price RM89 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:15PM | Duration 23h30 | Departure days Mon, Tue | Cheapest price RM100 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:20PM | Duration 20h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price RM91 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 10:35PM | Duration 23h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price RM150 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 03:15AM | Duration 27h40 | Departure days Everyday | Cheapest price RM107 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 03:15AM | Duration 27h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price RM88 |
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague buses for today, Friday, August 28. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 22h15 | 5:45 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h40 | 7:10 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 28h30 | 2:00 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 23h25 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h30 | 7:00 AM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 22h00 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 24h50 | 11:30 AM Praha, Zličín | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:40 AM Roma, Autostazione Tiburtina | 22h55 | 10:35 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:40 AM Roma, Autostazione Tiburtina | 24h05 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:00 PM Roma, Autostazione (Metro Anagnina) | 23h45 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 24h00 | 12:10 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 25h20 | 1:30 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 21h15 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 24h35 | 1:20 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 25h00 | 1:45 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 24h25 | 1:30 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 21h30 | 10:35 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 20h20 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 27h00 | 8:00 PM Prague, Central Train Station | 1 transfer | |
| FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h50 | 1:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 25h25 | 6:30 PM Praha, Zličín | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h25 | 4:30 PM Praha, Roztyly | 2 transfers | |
| FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h40 | 1:45 PM Prague, Central Train Station | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 24h30 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h05 | 4:10 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 20h05 | 1:30 PM Praha, ÚAN Florenc | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 22h45 | 4:10 PM Praha, Černý Most | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 25h45 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 19h55 | 1:20 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 24h10 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h45 | 5:45 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h30 | 5:30 PM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 22h10 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 26h55 | 11:55 PM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 24h00 | 10:55 PM Praha, Na Knížecí | 2 transfers | |
| FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 20h25 | 7:20 PM Prague, Central Train Station | 1 transfer | |
| FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 20h35 | 7:30 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 21h50 | 8:55 PM Praha, ÚAN Florenc | 1 transfer | |
| FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 22h25 | 9:30 PM Praha, Černý Most | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 23h30 | 10:35 PM Praha, Roztyly | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 27h20 | 2:25 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 27h40 | 3:15 AM Prague, Central Train Station | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 27h25 | 3:15 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Prague buses with Omio?
FlixBus operates all buses services from Rome to Prague.
Omio is an official ticket reseller for all your travel options from Rome to Prague.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.
Journey information
Overview: Bus from Rome to Prague
Italy
Czechia
Buses from Rome to Prague run on average 38 times per day, taking around 19h 57m. Cheap bus tickets for this journey start at RM56 but you can travel from only RM15 by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 573 miles (923 km) distance in 20h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from RM15
Distance 573 miles (923 km) |
Average bus duration 19h 57m |
Cheapest ticket price RM56 |
Buses per day 38 |
Direct buses 2 |
Fastest bus 20h 5m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 91 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from RM15
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as RM15. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
20h 5m
Cheapest Price
RM69
FlixBus frequency
39 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Prague
Things to do in Prague
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
- Must visit
Jewish Museum in Prague
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
- Recommended
National Gallery Prague – Schwarzenberg Palace
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
- Must visit
Old Town Square
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
- Must visit
Wenceslas Square
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
- Must visit
Malá Strana
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Svíčková na smetaně
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
- Gluten-free
Pečené vepřové koleno
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Vepřo knedlo zelo
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
U Kroka
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Mlýnec
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
La Degustation Bohême Bourgeoise
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Czech koruna (Kč)
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Average meal costs
- Budget
- Kč150-Kč250 for fast food or street food.
- Mid-range
- Kč300-Kč600 per person for a meal.
- Fine dining
- Kč1,200+ per person for upscale restaurants.
- Coffee
- Kč55-Kč85 for cappuccino.
Tipping culture
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
PID Lítačka
Get the appOfficial public transport app
Prices
- Single ticket
- 40 Kč
- Day pass
- 120 Kč
To the city center
Prague Central Train Station -> Wenceslas Square
- Distance
- 1 km
- Travel time
- 6 min
- Contactless card payment works in the PID Lítačka app and at many ticket machines; validate paper tickets before boarding.
- A 24-hour ticket covers metro, trams, buses, and ferries in Prague under PID.
FAQs: Bus from Rome to Prague
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Prague can start from as little as RM56 when you book in advance. The average bus ticket price for Rome to Prague is RM97 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Prague is 20h 5m to travel the 573 miles (923 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Prague leaves at 11:55 PM.
Yes, there are 2 direct buses a day from Rome to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Rome to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Rome and Prague and compare the amenities they offer before buying a bus ticket.
When departing from Rome , you have various bus station options to start your journey from including Roma, Autostazione Tiburtina, Roma, Autostazione (Metro Anagnina), Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" . When arriving in Prague , you can end your journey in bus stations like Prague, Central Train Station, Praha, ÚAN Florenc, Praha, Na Knížecí, Praha, Roztyly, Praha, Černý Most, Praha, M. Horákové (Hradčanská), Praha, Zličín, Praha, Letiště Václava Havla .Passengers board the bus most frequently from Roma, Autostazione Tiburtina, which is located around 2 miles (4 km) away from the city centre, and they get off the bus at Prague, Central Train Station, located 1 away from the city centre.
A trip to Prague from Rome is worth doing but not as a day trip with a journey time of 20h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Prague is February.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Rome to Prague:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rome to Prague for bus company FlixBus.
Some of the most interesting sights to explore in Prague are:
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
The best things to do in Prague include:
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
Whether you can cancel your bus ticket from Rome to Prague depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Prague.
Yes, the following luggage options are included when booking a bus ticket from Rome to Prague:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Prague:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rome to Prague. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Rome to Prague with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Rome to Prague with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Rome to Prague with the following bus company: FlixBus.
Since both Rome and Prague are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Rome to Prague among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rome to Prague
Most Rome to Prague buses use the Roma, Autostazione Tiburtina to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Rome and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rome
Arrival bus stations in Prague
Which Rome station do buses to Prague leave from?
Buses from Rome to Prague leave from Roma, Autostazione Tiburtina. The station is 2 miles (4 km) from Rome city centre at Largo Guido Mazzoni, snc, 00162 Roma RM, Italy.
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, Italy
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Bus490, 495 · 16m · RM2 · every ~22 min
SubwayMeb · 7m · RM2 · every ~15 min
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
BusRome Fiumicino, Scario · 31m · RM1
nMA · 38m · RM2 · every ~4 min
SubwayMea · 24m · RM2 · every ~29 min
Shuttle31m · RM10
Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine"
City-centre transport
Getting to Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" from Rome city centre
TrainRe, 12629 · 15m · RM2 · every ~8 min
BusN574, 522, 554, 546, N522 · 25m · RM1
30m · RM2
40m · RM7 · every ~3 min
SIT Bus Shuttle · 45m · RM4
Which Prague station do buses from Rome arrive at?
Buses from Rome to Prague most often arrive at Praha, Hlavní Nádraží. Some services arrive at Praha, ÚAN Florenc, so check your ticket before travel to confirm your Prague arrival station.
Praha, Hlavní NádražíWilsonova 300/8, 110 00 Praha 1, Czech Republic
City-centre transport
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
TrainRj, 600, 602, 604, 606, 608, 610, 612, 614, 616, 618, 670, 674, 676, 678, 680, 682, 684, 686, 688, 690, 692, 694, 696, 698, 2474, Re · 8m · RM1 · every ~3 min
Nj · 8m · RM14
Bus478 · 5m
Tram17, 93 · 10m · RM2 · every ~23 min
17, 93 · 12m · RM2 · every ~23 min
SubwayC · 5m · RM2 · every ~29 min
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN FlorencKrizikova 6, 186 00 Praha 8-Karlin, Czechia
City-centre transport
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Bus207, *888 · 9m · RM2 · every ~14 min
Tram3, 24, 31, 92, 94 · 13m · RM2 · every ~24 min
SubwayB · 2m · RM2 · every ~27 min
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na KnížecíNa Knizeci, Prague, Czech Republic
City-centre transport
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Bus907, 908 · 16m · RM2 · every ~1 min
N109, 084, N1759, N1309, 853, 109 · 20m · RM1 · every ~1 min
Tram12, 15, 20 · 11m · RM2 · every ~33 min
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
More options for your journey from Rome to Prague
Here are some other resources that might have the information you need
Most popular buses to and from Prague and Rome
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