The cheapest and fastest buses from Rome to Prague
Cheapest price
$154
Average price
$199
Fastest journey
20 h 20 m
Average duration
20 h 29 m
Buses per day
41
Distance
923 km
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around $199 if you buy it on the day, but the cheapest tickets can be found for only $154.
Of the 41 buses that leave Rome for Prague on Sun, Nov 30, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Nov 30 the direct buses cover the 923 km distance in an average of 20 h 29 m but if you time it right, some buses will get you there in just 20 h 20 m .
On Sun, Nov 30 the slowest buses will take 20 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBusTravel Information
Compare train, bus, and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €64. For those with little time consider booking a flight which can get you there in 2h 48m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of €64, and a train costs an average of €131.
Distance: 573 miles (923 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€114 Average price Cheapest | €138 Average price | €174 Average price |
20h 8m Average total duration 19h 38m Onboard + 30m Additional time* | 5h 48m Average total duration Fastest 2h 48m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:40AM | Arrival Time 05:45AM | Duration 28h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $161 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:45AM | Duration 22h15 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $128 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 08:15AM | Duration 24h20 | Departure days Sun | Cheapest price $212 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 12:25PM | Duration 26h55 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $116 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 08:45AM | Duration 22h30 | Departure days Sat | Cheapest price $146 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 11:30AM | Duration 24h50 | Departure days Everyday | Cheapest price $120 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 10:35AM | Duration 23h25 | Departure days Thu | Cheapest price $137 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 12:25PM | Duration 24h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 12:10PM | Duration 24h00 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $138 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 01:30PM | Duration 25h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $130 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:30PM | Duration 24h45 | Departure days Thu, Sun | Cheapest price $125 |
Operator Regiojet | Departure Time 01:00PM | Arrival Time 09:10AM | Duration 20h10 | Departure days Wed | Cheapest price $98 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 01:40PM | Duration 24h35 | Departure days Everyday | Cheapest price $111 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 08:00PM | Duration 27h00 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 04:30PM | Duration 23h25 | Departure days Everyday | Cheapest price $132 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 05:35PM | Duration 24h10 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 09:30PM | Duration 24h30 | Departure days Everyday | Cheapest price $98 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 09:50PM | Duration 24h30 | Departure days Mon, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:15PM | Duration 23h30 | Departure days Mon, Sun | Cheapest price $135 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 10:55PM | Duration 24h00 | Departure days Wed, Thu, Fri, Sat | Cheapest price $150 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 10:35PM | Duration 23h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $140 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 03:15AM | Duration 27h40 | Departure days Wed, Fri, Sat, Sun | Cheapest price $130 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 03:15AM | Duration 27h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price $113 |
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague buses for tomorrow, Sunday, November 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 12:40 AM Roma, Autostazione Tiburtina | 25h35 | 2:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 6:30 AM Roma, Autostazione Tiburtina | 22h15 | 4:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:55 AM Roma, Autostazione Tiburtina | 24h20 | 7:15 AM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 20h30 | 5:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 20h45 | 5:15 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 22h10 | 6:40 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 26h00 | 10:30 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:40 AM Roma, Autostazione Tiburtina | 24h50 | 10:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 AM Roma, Autostazione (Metro Anagnina) | 24h35 | 11:25 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 AM Roma, Autostazione Tiburtina | 22h45 | 9:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:10 AM Roma, Autostazione Tiburtina | 24h00 | 11:10 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 11:20 AM Roma, Autostazione Tiburtina | 25h10 | 12:30 PM Praha, Roztyly | 1 transfer | |
FlixBus · FlixBus | 11:20 AM Roma, Autostazione Tiburtina | 21h05 | 8:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:20 AM Roma, Autostazione Tiburtina | 24h05 | 11:25 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:45 AM Roma, Autostazione (Metro Anagnina) | 21h50 | 9:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 24h25 | 12:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 23h05 | 11:10 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 20h20 | 8:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:00 PM Roma, Autostazione Tiburtina | 27h00 | 7:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:00 PM Roma, Autostazione Tiburtina | 26h45 | 6:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 20h45 | 12:50 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 23h05 | 3:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 24h30 | 4:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 25h25 | 5:30 PM Praha, Zličín | 2 transfers | |
FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 20h35 | 12:40 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 23h25 | 3:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 PM Roma, Autostazione (Metro Anagnina) | 20h40 | 1:05 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 PM Roma, Autostazione (Metro Anagnina) | 22h45 | 3:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 PM Roma, Autostazione (Metro Anagnina) | 24h10 | 4:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:25 PM Roma, Autostazione (Metro Anagnina) | 20h30 | 12:55 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 20h30 | 4:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 23h20 | 7:20 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 20h45 | 4:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 25h15 | 9:15 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 26h55 | 10:55 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 8:20 PM Roma, Autostazione Tiburtina | 24h30 | 8:50 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 23h30 | 9:15 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 10:05 PM Roma, Autostazione Tiburtina | 22h50 | 8:55 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:05 PM Roma, Autostazione Tiburtina | 23h30 | 9:35 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus | 10:05 PM Roma, Autostazione Tiburtina | 22h15 | 8:20 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:35 PM Roma, Autostazione (Metro Anagnina) | 27h40 | 2:15 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Rome to Prague
Buses from Rome to Prague run on average 37 times per day, taking around 19h 38m. Cheap bus tickets for this journey start at $79 (€64) but you can travel from only $38 (€31) by flight.
There are 1 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 573 miles (923 km) distance in 20h 10m.
Distance 573 miles (923 km) |
Average bus duration 19h 38m |
Cheapest ticket price $79 (€64) |
Buses per day 37 |
Direct buses 1 |
Fastest bus 20h 10m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as $38 (€31). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Rome to Prague
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Rome to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Prague
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Cafeteria Černý Most (in the station)
- Czech Bistro (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 177, 195, 201 Metro: B
- Bus: 131, 174, 180 Metro: A Train: S4, S5
More options for your journey from Rome to Prague
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