- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$88
Average price
$146
Fastest journey
19 h 55 m
Average duration
20 h 11 m
Buses per day
41
Distance
923 km
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around $146 if you buy it on the day, but the cheapest tickets can be found for only $88.
Of the 41 buses that leave Rome for Prague on Wed, Jul 15, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 15 the direct buses cover the 923 km distance in an average of 20 h 11 m but if you time it right, some buses will get you there in just 19 h 55 m .
On Wed, Jul 15 the slowest buses will take 20 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Rome -> Prague)
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
(Rome -> Prague)
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 2h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $68, and a train costs an average of $287.
Distance: 573 miles (923 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$111 Average price Cheapest | $148 Average price | $291 Average price | $351 Average price (fuel + tolls) |
20h 23m Average total duration 19h 53m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 2h 50m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* | 13h 23m Average total duration (door-to-door) |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Rome to Prague:
A bus is $37 (€31) less than a flight for this route with tickets for a flight from Rome to Prague costing on average $148 (€122).
A bus is $180 (€148) less than a train for this route with tickets for a train from Rome to Prague costing on average $291 (€239).
Other travel options to Prague take longer:
Train takes on average 17h 32m.
Bus takes on average 19h 53m.
Tickets start at around $111 (€91) compared to roughly $351 (€288) in fuel and tolls — a saving of about $240 (€197). The journey takes 19h 53m versus 13h 23m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:45AM | Duration 22h15 | Departure days Everyday | Cheapest price $128 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 07:30AM | Duration 22h00 | Departure days Everyday | Cheapest price $129 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 11:30AM | Duration 24h50 | Departure days Everyday | Cheapest price $136 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 10:35AM | Duration 22h55 | Departure days Fri | Cheapest price $168 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 12:45PM | Duration 24h45 | Departure days Everyday | Cheapest price $133 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 10:35AM | Duration 22h25 | Departure days Everyday | Cheapest price $139 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 12:45PM | Duration 24h25 | Departure days Everyday | Cheapest price $136 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:20PM | Duration 24h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $147 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 09:10AM | Duration 20h10 | Departure days Wed, Sun | Cheapest price $88 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 05:35PM | Duration 28h30 | Departure days Everyday | Cheapest price $131 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 05:35PM | Duration 24h35 | Departure days Everyday | Cheapest price $133 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 01:55PM | Duration 20h50 | Departure days Everyday | Cheapest price $114 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 07:10PM | Duration 25h45 | Departure days Everyday | Cheapest price $127 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 05:30PM | Duration 20h30 | Departure days Everyday | Cheapest price $128 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 08:05PM | Duration 22h45 | Departure days Mon, Tue | Cheapest price $135 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 10:15PM | Duration 23h30 | Departure days Mon, Tue | Cheapest price $155 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:20PM | Duration 20h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $156 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 02:25AM | Duration 27h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $164 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 03:15AM | Duration 27h40 | Departure days Everyday | Cheapest price $141 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 03:15AM | Duration 27h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $156 |
The table below shows live departures for Rome to Prague buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 22h15 | 5:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 22h00 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h30 | 7:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 23h25 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h40 | 7:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 28h30 | 2:00 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 24h50 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:00 PM Roma, Autostazione (Metro Anagnina) | 24h45 | 12:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 22h25 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 24h25 | 12:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 21h05 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h10 | 1:30 PM Praha, Roztyly | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 28h30 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 24h25 | 1:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 21h30 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 20h20 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 24h35 | 5:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 27h00 | 8:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h50 | 1:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h40 | 1:45 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h05 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h25 | 4:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 25h45 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 22h45 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 20h05 | 1:30 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 19h55 | 1:20 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h30 | 5:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 26h55 | 11:55 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 22h10 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h45 | 5:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 24h30 | 9:30 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 9:20 PM Roma, Autostazione Tiburtina | 22h45 | 8:05 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 9:20 PM Roma, Autostazione Tiburtina | 22h55 | 8:15 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 23h30 | 10:15 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 27h40 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 27h25 | 3:15 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Rome to Prague run on average 38 times per day, taking around 19h 53m. Cheap bus tickets for this journey start at $68 (€56) but you can travel from only $19 (€15) by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 573 miles (923 km) distance in 20h 10m.
Distance 573 miles (923 km) |
Average bus duration 19h 53m |
Cheapest ticket price $68 (€56) |
Buses per day 38 |
Direct buses 2 |
Fastest bus 20h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 28 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need