Rome to Prague bus with FlixBus

Tue, Oct 13
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The cheapest and fastest buses from Rome to Prague

Showing times, prices and bookable tickets for Oct 13

Cheapest price on Oct 13

$113

Average ticket price on Oct 13

$127

Fastest journey on Oct 13

20 h 20 m

Average journey duration on Oct 13

20 h 37 m

Buses on Oct 13

30

Distance

923 km

Cheap tickets

The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Rome to Prague will cost around $127 if you buy it on the day, but the cheapest tickets can be found for only $113.

Fast buses

On Tue, Oct 13, we found 30 buses from Rome to Prague, including 2 direct services.

On Tue, Oct 13 the direct buses cover the 923 km distance in an average of 20 h 37 m but if you time it right, some buses will get you there in just 20 h 20 m .

On Tue, Oct 13 the slowest buses will take 20 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBusFlixBus · FlixBus
    5:00 PM27h00
    Roma, Autostazione Tiburtina
    8:00 PMPrague, Central Train Station
    $1131One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    11:00 AM25h45
    Roma, Autostazione (Metro Anagnina)
    12:45 PMPraha, Na Knížecí
    $1141One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    9:00 PM20h30
    Roma, Autostazione Tiburtina
    5:30 PMPrague, Central Train Station
    $1141One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    9:00 PM20h45
    Roma, Autostazione Tiburtina
    5:45 PMPraha, ÚAN Florenc
    $1141One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    5:05 PM23h25
    Roma, Autostazione Tiburtina
    4:30 PMPraha, Roztyly
    $1151One-way
    2 transfers

Journey information

Overview: Bus from Rome to Prague

ItalyItaly
CzechiaCzechia
Icon of bus

Buses from Rome to Prague run on average 38 times per day, taking around 19h 49m. Cheap bus tickets for this journey start at $53 but you can travel from only $20 by flight.

There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 573 miles (923 km) distance in 16h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $20
Distance
573 miles (923 km)
Average bus duration
19h 49m
Cheapest ticket price
$53
Buses per day
38
Direct buses
2
Fastest bus
16h 50m
First bus
12:10 AM
Last bus
11:55 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jul - Sep
Low Season
Apr - Jun
Busiest Day
Wed
Least Busy Day
Thu
Best time to book
91 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $20

Rome to Prague Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
01:20AM
Arrival Time
03:15AM
Duration
25h55
Departure days
Tue, Wed, Thu, Fri, Sat, Sun
Cheapest price
$119
Operator
FlixBus
Departure Time
07:30AM
Arrival Time
05:45AM
Duration
22h15
Departure days
Thu, Fri, Sat, Sun
Cheapest price
$105
Operator
FlixBus
Departure Time
08:30AM
Arrival Time
11:30AM
Duration
27h00
Departure days
Mon
Cheapest price
$152
Operator
FlixBus
Departure Time
09:30AM
Arrival Time
08:55AM
Duration
23h25
Departure days
Everyday
Cheapest price
$103
Operator
FlixBus
Departure Time
10:40AM
Arrival Time
11:30AM
Duration
24h50
Departure days
Tue, Wed, Thu, Fri, Sat, Sun
Cheapest price
$117
Operator
FlixBus
Departure Time
11:00AM
Arrival Time
12:45PM
Duration
25h45
Departure days
Tue, Wed
Cheapest price
$101
Operator
FlixBus
Departure Time
12:00PM
Arrival Time
12:45PM
Duration
24h45
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$117
Operator
FlixBus
Departure Time
12:20PM
Arrival Time
12:45PM
Duration
24h25
Departure days
Everyday
Cheapest price
$101
Operator
FlixBus
Departure Time
12:45PM
Arrival Time
01:20PM
Duration
24h35
Departure days
Thu, Fri, Sat, Sun
Cheapest price
$122
Operator
RegioJet a.s.
Departure Time
01:00PM
Arrival Time
09:10AM
Duration
20h10
Departure days
Wed
Cheapest price
$67
Operator
FlixBus
Departure Time
01:05PM
Arrival Time
01:30PM
Duration
24h25
Departure days
Everyday
Cheapest price
$105
Operator
FlixBus
Departure Time
05:00PM
Arrival Time
07:50PM
Duration
26h50
Departure days
Everyday
Cheapest price
$106
Operator
FlixBus
Departure Time
05:05PM
Arrival Time
01:45PM
Duration
20h40
Departure days
Everyday
Cheapest price
$110
Operator
FlixBus
Departure Time
05:25PM
Arrival Time
01:30PM
Duration
20h05
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$100
Operator
FlixBus
Departure Time
06:15PM
Arrival Time
08:55PM
Duration
26h40
Departure days
Everyday
Cheapest price
$113
Operator
FlixBus
Departure Time
08:00PM
Arrival Time
08:20PM
Duration
24h20
Departure days
Mon, Tue
Cheapest price
$142
Operator
FlixBus
Departure Time
09:00PM
Arrival Time
05:30PM
Duration
20h30
Departure days
Everyday
Cheapest price
$103
Operator
FlixBus
Departure Time
09:20PM
Arrival Time
09:50PM
Duration
24h30
Departure days
Mon
Cheapest price
$124
Operator
FlixBus
Departure Time
10:45PM
Arrival Time
09:30PM
Duration
22h45
Departure days
Tue, Wed
Cheapest price
$119
Operator
FlixBus
Departure Time
10:55PM
Arrival Time
07:20PM
Duration
20h25
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$106
Operator
FlixBus
Departure Time
11:05PM
Arrival Time
10:35PM
Duration
23h30
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$107
Operator
FlixBus
Departure Time
11:35PM
Arrival Time
03:15AM
Duration
27h40
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$128

Live departures

Rome to Prague bus times

The table below shows live departures for Rome to Prague buses for today, Monday, October 12. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus · FlixBus12:00 PM Roma, Autostazione (Metro Anagnina)
24h45
12:45 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
25h00
1:20 PM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
25h10
1:30 PM Praha, Roztyly1 transfer
FlixBusFlixBus · FlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
24h25
12:45 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
21h05
9:25 AM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
28h30
5:35 PM Praha, M. Horákové (Hradčanská)2 transfers
FlixBusFlixBus · FlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
27h05
4:10 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
24h25
1:30 PM Praha, Roztyly2 transfers
FlixBusFlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
20h20
9:25 AM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
21h30
10:35 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus5:00 PM Roma, Autostazione Tiburtina
24h35
5:35 PM Praha, M. Horákové (Hradčanská)1 transfer
FlixBusFlixBus · FlixBus5:00 PM Roma, Autostazione Tiburtina
27h00
8:00 PM Prague, Central Train Station1 transfer
FlixBusFlixBus5:05 PM Roma, Autostazione Tiburtina
20h50
1:55 PM Praha, ÚAN Florenc0 transfersDirect
FlixBusFlixBus · FlixBus · FlixBus5:05 PM Roma, Autostazione Tiburtina
23h25
4:30 PM Praha, Roztyly2 transfers
FlixBusFlixBus5:05 PM Roma, Autostazione Tiburtina
20h40
1:45 PM Prague, Central Train Station0 transfersDirect
FlixBusFlixBus · FlixBus · FlixBus5:05 PM Roma, Autostazione Tiburtina
26h05
7:10 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:05 PM Roma, Autostazione Tiburtina
23h05
4:10 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus6:15 PM Roma, Autostazione (Metro Anagnina)
26h40
8:55 PM Praha, ÚAN Florenc2 transfers
FlixBusFlixBus · FlixBus · FlixBus6:15 PM Roma, Autostazione (Metro Anagnina)
27h15
9:30 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus8:00 PM Roma, Autostazione Tiburtina
24h20
8:20 PM Praha, Na Knížecí1 transfer
FlixBusFlixBus · FlixBus9:00 PM Roma, Autostazione Tiburtina
20h30
5:30 PM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus9:00 PM Roma, Autostazione Tiburtina
20h45
5:45 PM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus9:00 PM Roma, Autostazione Tiburtina
24h10
9:10 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus9:20 PM Roma, Autostazione Tiburtina
24h30
9:50 PM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus11:05 PM Roma, Autostazione Tiburtina
21h50
8:55 PM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus11:05 PM Roma, Autostazione Tiburtina
22h25
9:30 PM Praha, Černý Most1 transfer
FlixBusFlixBus · FlixBus · FlixBus11:05 PM Roma, Autostazione Tiburtina
23h30
10:35 PM Praha, Roztyly2 transfers
FlixBusFlixBus · FlixBus · FlixBus11:35 PM Roma, Autostazione (Metro Anagnina)
27h40
3:15 AM Prague, Central Train Station2 transfers
Tuesday, October 13
FlixBusFlixBus · FlixBus · FlixBus1:20 AM Roma, Autostazione Tiburtina
25h55
3:15 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
21h30
7:00 AM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
22h00
7:30 AM Praha, M. Horákové (Hradčanská)2 transfers
FlixBusFlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
21h40
7:10 AM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
23h25
8:55 AM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
28h30
2:00 PM Prague, Central Train Station2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Why should you book Rome to Prague buses with Omio?

FlixBus operates all buses services from Rome to Prague.
Omio is an official ticket reseller for all your travel options from Rome to Prague.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.

Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as $20. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 50m
Cheapest FlixBus Price
$53
FlixBus frequency
41 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Prague

Things to do in Prague

Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.

  • Must visit

National Museum

Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.

  • Must visit

Jewish Museum in Prague

Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.

  • Recommended

National Gallery Prague – Schwarzenberg Palace

Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.

Czech koruna (Kč)

Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.

Average meal costs

Budget
Kč150-Kč250 for fast food or street food.
Mid-range
Kč300-Kč600 per person for a meal.
Fine dining
Kč1,200+ per person for upscale restaurants.
Coffee
Kč55-Kč85 for cappuccino.

Tipping culture

Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.

FAQs: Bus from Rome to Prague

Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Rome to Prague can start from as little as $53 when you book in advance. The average bus ticket price for Rome to Prague is $111 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Prague is 16h 50m to travel the 573 miles (923 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Prague leaves at 11:55 PM.
Yes, there are 2 direct buses a day from Rome to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Rome to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible bus companies who offer a service between Rome and Prague and compare the amenities they offer before buying a bus ticket.
When departing from Rome , you have various bus station options to start your journey from including Roma, Autostazione Tiburtina, Roma, Autostazione (Metro Anagnina), Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" . When arriving in Prague , you can end your journey in bus stations like Prague, Central Train Station, Praha, ÚAN Florenc, Praha, Na Knížecí, Praha, Roztyly, Praha, Černý Most, Praha, M. Horákové (Hradčanská), Praha, Zličín, Praha, Letiště Václava Havla .Passengers board the bus most frequently from Roma, Autostazione Tiburtina, which is located around 2 miles (4 km) away from the city centre, and they get off the bus at Prague, Central Train Station, located 1 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Rome to Prague:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rome to Prague for bus company FlixBus.
Whether you can cancel your bus ticket from Rome to Prague depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Prague.
Yes, the following luggage options are included when booking a bus ticket from Rome to Prague:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Prague:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rome to Prague. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Rome to Prague with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Rome to Prague with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Rome to Prague with the following bus company: FlixBus.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Prague, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, Old Town Square, and major tourist sites. Common scams include overpriced taxi rides without meters, street vendors selling fake tickets or souvenirs, and distraction techniques used by thieves. It's advisable to use official taxis or ride-hailing apps, keep valuables secure, and be wary of strangers offering unsolicited help.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Rome to Prague

Most Rome to Prague buses use the Roma, Autostazione Tiburtina to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Rome and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Rome
Arrival bus stations in Prague

Which Rome station do buses to Prague leave from?

Buses from Rome to Prague leave from Roma, Autostazione Tiburtina. The station is 2 miles (4 km) from Rome city centre at Largo Guido Mazzoni, snc, 00162 Roma RM, Italy.
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, ItalyWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Roma, Autostazione Tiburtina from Rome city centre

Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:

Bus490, 495 · 16m · $2 · every ~22 min
SubwayMeb · 7m · $2 · every ~15 min

Roma, Autostazione Tiburtina bus station facilities and services

Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Cafes and vending machines available.

Wi-Fi and ATMs

Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.

Tickets and information

Ticket office support is available at Roma, Autostazione Tiburtina.

Parking, taxis and toilets

Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.

Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport

Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre

BusRome Fiumicino, Scario · 31m · $1
nMA · 38m · $2 · every ~4 min
SubwayMea · 24m · $2 · every ~29 min
Shuttle31m · $12
Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine"
City-centre transport

Getting to Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" from Rome city centre

TrainRe, 12629 · 15m · $2 · every ~8 min
BusN574, 522, 554, 546, N522 · 25m · $1
30m · $2
40m · $8 · every ~3 min
SIT Bus Shuttle · 45m · $5

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