- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Oct 13
$113
Average ticket price on Oct 13
$127
Fastest journey on Oct 13
20 h 20 m
Average journey duration on Oct 13
20 h 37 m
Buses on Oct 13
30
Distance
923 km
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around $127 if you buy it on the day, but the cheapest tickets can be found for only $113.
On Tue, Oct 13, we found 30 buses from Rome to Prague, including 2 direct services.
On Tue, Oct 13 the direct buses cover the 923 km distance in an average of 20 h 37 m but if you time it right, some buses will get you there in just 20 h 20 m .
On Tue, Oct 13 the slowest buses will take 20 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBusBuses from Rome to Prague run on average 38 times per day, taking around 19h 49m. Cheap bus tickets for this journey start at $53 but you can travel from only $20 by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 573 miles (923 km) distance in 16h 50m.
Distance 573 miles (923 km) |
Average bus duration 19h 49m |
Cheapest ticket price $53 |
Buses per day 38 |
Direct buses 2 |
Fastest bus 16h 50m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 91 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 03:15AM | Duration 25h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:45AM | Duration 22h15 | Departure days Thu, Fri, Sat, Sun | Cheapest price $105 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 11:30AM | Duration 27h00 | Departure days Mon | Cheapest price $152 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 08:55AM | Duration 23h25 | Departure days Everyday | Cheapest price $103 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 11:30AM | Duration 24h50 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $117 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 12:45PM | Duration 25h45 | Departure days Tue, Wed | Cheapest price $101 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 12:45PM | Duration 24h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $117 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 12:45PM | Duration 24h25 | Departure days Everyday | Cheapest price $101 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:20PM | Duration 24h35 | Departure days Thu, Fri, Sat, Sun | Cheapest price $122 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 09:10AM | Duration 20h10 | Departure days Wed | Cheapest price $67 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 01:30PM | Duration 24h25 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 07:50PM | Duration 26h50 | Departure days Everyday | Cheapest price $106 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 01:45PM | Duration 20h40 | Departure days Everyday | Cheapest price $110 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 01:30PM | Duration 20h05 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 08:55PM | Duration 26h40 | Departure days Everyday | Cheapest price $113 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 08:20PM | Duration 24h20 | Departure days Mon, Tue | Cheapest price $142 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 05:30PM | Duration 20h30 | Departure days Everyday | Cheapest price $103 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 09:50PM | Duration 24h30 | Departure days Mon | Cheapest price $124 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 09:30PM | Duration 22h45 | Departure days Tue, Wed | Cheapest price $119 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:20PM | Duration 20h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 10:35PM | Duration 23h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 03:15AM | Duration 27h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $128 |
The table below shows live departures for Rome to Prague buses for today, Monday, October 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 12:00 PM Roma, Autostazione (Metro Anagnina) | 24h45 | 12:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h00 | 1:20 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h10 | 1:30 PM Praha, Roztyly | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 24h25 | 12:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 21h05 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 28h30 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 27h05 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 24h25 | 1:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 20h20 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 21h30 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 24h35 | 5:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 27h00 | 8:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h50 | 1:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h25 | 4:30 PM Praha, Roztyly | 2 transfers | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h40 | 1:45 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 26h05 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h05 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:15 PM Roma, Autostazione (Metro Anagnina) | 26h40 | 8:55 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:15 PM Roma, Autostazione (Metro Anagnina) | 27h15 | 9:30 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 24h20 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h30 | 5:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h45 | 5:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 24h10 | 9:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 9:20 PM Roma, Autostazione Tiburtina | 24h30 | 9:50 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 21h50 | 8:55 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 22h25 | 9:30 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 23h30 | 10:35 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 27h40 | 3:15 AM Prague, Central Train Station | 2 transfers | |
| Tuesday, October 13 | |||||
FlixBus · FlixBus · FlixBus | 1:20 AM Roma, Autostazione Tiburtina | 25h55 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h30 | 7:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 22h00 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 21h40 | 7:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 23h25 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 28h30 | 2:00 PM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Rome to Prague buses use the Roma, Autostazione Tiburtina to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Rome and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need