The cheapest and fastest buses from Karlsruhe to Frankfurt am Main
Cheapest price
$11
Average price
$20
Fastest journey
1 h 10 m
Average duration
1 h 24 m
Buses per day
17
Distance
125 km
The best way to find a cheap bus ticket from Karlsruhe to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Frankfurt am Main will cost around $20 if you buy it on the day, but the cheapest tickets can be found for only $11.
Of the 17 buses that leave Karlsruhe for Frankfurt am Main on Wed, Feb 04, 17 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Feb 04 the direct buses cover the 125 km distance in an average of 1 h 24 m but if you time it right, some buses will get you there in just 1 h 10 m .
On Wed, Feb 04 the slowest buses will take 1 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
FlixBus
FlixBus





Travel Information
Compare bus and train for Karlsruhe to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Karlsruhe to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €6. For those with little time consider booking a train which can get you there in 1h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of €6, and a train costs an average of €7.
Distance: 77 miles (125 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€8 Average price Cheapest | €17 Average price |
2h 28m Average total duration 1h 58m Onboard + 30m Additional time* | 1h 51m Average total duration Fastest 1h 21m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Karlsruhe to Frankfurt am Main Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:15AM | Arrival Time 05:50AM | Duration 2h35 | Departure days Tue, Wed | Cheapest price $16 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 06:00AM | Duration 2h10 | Departure days Tue | Cheapest price $13 |
Operator FlixBus | Departure Time 05:55AM | Arrival Time 08:10AM | Duration 2h15 | Departure days Tue | Cheapest price $12 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 08:55AM | Duration 2h15 | Departure days Tue, Wed | Cheapest price $12 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 09:30AM | Duration 2h40 | Departure days Tue, Wed | Cheapest price $14 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 10:45AM | Duration 2h30 | Departure days Tue, Wed | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 11:30AM | Duration 1h30 | Departure days Wed | Cheapest price $16 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 01:30PM | Duration 2h15 | Departure days Tue, Wed | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 11:20AM | Arrival Time 12:40PM | Duration 1h20 | Departure days Tue | Cheapest price $12 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 02:15PM | Duration 2h35 | Departure days Tue | Cheapest price $14 |
Operator FlixBus | Departure Time 02:05PM | Arrival Time 04:40PM | Duration 2h35 | Departure days Tue, Wed | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 02:10PM | Arrival Time 03:30PM | Duration 1h20 | Departure days Wed | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 04:30PM | Duration 1h30 | Departure days Wed | Cheapest price $14 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 06:15PM | Duration 2h55 | Departure days Tue, Wed | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 04:10PM | Arrival Time 05:20PM | Duration 1h10 | Departure days Tue | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 04:30PM | Arrival Time 06:00PM | Duration 1h30 | Departure days Wed | Cheapest price $16 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 07:05PM | Duration 2h30 | Departure days Tue | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 04:50PM | Arrival Time 06:30PM | Duration 1h40 | Departure days Tue | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 07:40PM | Arrival Time 08:50PM | Duration 1h10 | Departure days Wed | Cheapest price $11 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 10:30PM | Duration 2h10 | Departure days Tue, Wed | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 08:40PM | Arrival Time 09:50PM | Duration 1h10 | Departure days Tue | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 08:50PM | Arrival Time 10:00PM | Duration 1h10 | Departure days Tue | Cheapest price $13 |
Live departures
Karlsruhe to Frankfurt am Main bus times
The table below shows live departures for Karlsruhe to Frankfurt am Main buses for today, Tuesday, February 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 3:35 PM Karlsruhe Hbf | 2h30 | 6:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 7:20 PM Karlsruhe Hbf | 2h10 | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
| Wednesday, February 4 | |||||
FlixBus | 2:15 AM Karlsruhe Hbf | 2h15 | 4:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 2:15 AM Karlsruhe Hbf | 2h35 | 4:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 5:40 AM Karlsruhe Hbf | 2h15 | 7:55 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 5:50 AM Karlsruhe Hbf | 2h20 | 8:10 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 5:50 AM Karlsruhe Hbf | 2h40 | 8:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 7:15 AM Karlsruhe Hbf | 2h05 | 9:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 7:15 AM Karlsruhe Hbf | 2h30 | 9:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 10:15 AM Karlsruhe Hbf | 2h15 | 12:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 1:05 PM Karlsruhe Hbf | 2h35 | 3:40 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 2:20 PM Karlsruhe Hbf | 2h55 | 5:15 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 2:20 PM Karlsruhe Hbf | 2h35 | 4:55 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Frankfurt am Main by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Feb 12
Feb 13
Feb 14
Feb 15
Feb 16
Feb 17
Feb 18
Feb 19
Feb 20
Feb 21
Feb 22
Feb 23
Feb 24
Why should you book Karlsruhe to Frankfurt am Main buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus, Infobus, Globtour Medjugorjie or Centrotrans Eurolines to find the best option for your trip from Karlsruhe to Frankfurt am Main.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlsruhe to Frankfurt am Main.
Why book with Omio over Wanderu or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus, Infobus, Globtour Medjugorjie or Centrotrans Eurolines to find the best option for your trip from Karlsruhe to Frankfurt am Main.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlsruhe to Frankfurt am Main.
Journey information
Overview: Bus from Karlsruhe to Frankfurt am Main
Buses from Karlsruhe to Frankfurt am Main run on average 26 times per day, taking around 1h 58m. Cheap bus tickets for this journey start at $8 (€6) if you book in advance.
There are 26 buses per day. The earliest bus runs at 00:40, the last at 23:55. The fastest bus covers the 77 miles (125 km) distance in 2h 10m.
Distance 77 miles (125 km) |
Average bus duration 1h 58m |
Cheapest ticket price $8 (€6) |
Buses per day 26 |
Direct buses 26 |
Fastest bus 2h 10m |
First bus 00:40 |
Last bus 23:55 |
Bus providers: FlixBus, BlaBlaCar, BlaBlaCar Bus, Globtour Medjugorjie, Infobus, Centrotrans Eurolines from Karlsruhe to Frankfurt am MainYou can travel by bus between Karlsruhe to Frankfurt am Main with FlixBus, BlaBlaCar, BlaBlaCar Bus, Globtour Medjugorjie, Infobus, Centrotrans Eurolines for as low as $8 (€6). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
Globtour Medjugorjie
BlaBlaCar
Centrotrans Eurolines
FAQs: Bus from Karlsruhe to Frankfurt am Main
Find answers to the most common questions about traveling from Karlsruhe to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Römer, a historic city hall with medieval architecture located in the heart of Frankfurt's old town
- Städel Museum, an art museum featuring a vast collection of European artworks from the Middle Ages to the present
- Palmengarten, a large botanical garden showcasing diverse plant species in themed greenhouses and outdoor areas
- Goethe House, the birthplace of the famous writer Johann Wolfgang von Goethe, now a museum dedicated to his life and works
- Frankfurt Cathedral, a Gothic-style church with a rich history and stunning architecture.
- Main Tower, a skyscraper with an observation deck providing panoramic views of the city
- Explore the vibrant Kleinmarkthalle, an indoor market offering a variety of local and international foods
- Visit the Senckenberg Natural History Museum, home to an extensive collection of dinosaur fossils and natural exhibits
- Take a leisurely walk along the River Main and enjoy the scenic views
- Experience the lively atmosphere of the Zeil, Frankfurt's premier shopping street.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Globtour Medjugorjie
- A passenger can receive a partial refund if a written request is submitted at least 24 hours before the journey (25% fee) or between 24 and 12 hours before (50% fee)
- tickets cannot be canceled or refunded within 12 hours of departure.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Globtour Medjugorjie
- An additional fee may be charged by the driver for storing luggage in the compartment, with prices varying by route.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Karlsruhe to Frankfurt am Main
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
- 06:00-22:00
- Free Wi-Fi
- Bakery & Café (in the station)
- Fast Food Express (in the station)
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 61, 78 Train: S3, S4, S5, S6 Tram: 15, 16
Most popular bus connections from Karlsruhe
More options for your journey from Karlsruhe to Frankfurt am Main
Here are some other resources that might have the information you need

