- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 13
€73
Average ticket price on Sep 13
€98
Fastest journey on Sep 13
16 h 25 m
Average journey duration on Sep 13
17 h 41 m
Buses on Sep 13
16
Distance
852 km
The best way to find a cheap bus ticket from Karlsruhe to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Rome will cost around €98 if you buy it on the day, but the cheapest tickets can be found for only €73.
On Sun, Sep 13, we found 16 buses from Karlsruhe to Rome, including 1 direct services.
On Sun, Sep 13 the direct buses cover the 852 km distance in an average of 17 h 41 m but if you time it right, some buses will get you there in just 16 h 25 m .
On Sun, Sep 13 the slowest buses will take 18 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Karlsruhe to Rome among Omio's users. If you are prioritising price, take the train, with an average ticket price of €28 For those with little time, consider booking a train, which has an average total journey time of 9h 49m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.1kg. Average ticket prices depend on the travel mode: a train costs an average of €28, while a bus costs an average of €96.
Distance: 529 miles (852 km)
Most popular Bus | Train | Driving |
|---|---|---|
€96 Average price | €28 Average price Cheapest | €277 Average price (fuel + tolls) |
17h 42m Average total duration 17h 12m Onboard + 30m Additional time* | 9h 49m Average total duration Fastest 9h 19m Onboard + 30m Additional time* | 12h 4m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Rome:
A train is €68 less than a bus for this route with tickets for a bus from Karlsruhe to Rome costing on average €96.
A train is €90 less than a flight for this route with tickets for a flight from Karlsruhe to Rome costing on average €118.
Other travel options to Rome take longer:
Train takes on average 9h 19m.
Bus takes on average 17h 12m.
Tickets start at around €96 compared to roughly €277 in fuel and tolls — a saving of about €180. The journey takes 17h 12m versus 12h 4m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:20AM | Arrival Time 09:10PM | Duration 17h50 | Departure days Everyday | Cheapest price €62 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 11:00PM | Duration 18h05 | Departure days Everyday | Cheapest price €58 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 11:40PM | Duration 18h25 | Departure days Sat, Sun | Cheapest price €78 |
Operator Marino Autolinee | Departure Time 09:30AM | Arrival Time 04:30AM | Duration 19h00 | Departure days Thu, Sat | Cheapest price €99 |
Operator FlixBus | Departure Time 10:26AM | Arrival Time 08:40AM | Duration 22h14 | Departure days Mon, Fri, Sat | Cheapest price €72 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 06:05AM | Duration 19h00 | Departure days Everyday | Cheapest price €64 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 09:20AM | Duration 22h05 | Departure days Tue, Wed | Cheapest price €58 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 07:05AM | Duration 18h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €73 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 09:30AM | Duration 19h30 | Departure days Mon, Tue, Wed | Cheapest price €58 |
Operator FlixBus | Departure Time 02:23PM | Arrival Time 01:20PM | Duration 22h57 | Departure days Tue, Wed, Thu, Sun | Cheapest price €69 |
Operator FlixBus | Departure Time 03:29PM | Arrival Time 04:30PM | Duration 25h01 | Departure days Mon, Tue, Wed, Thu | Cheapest price €70 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 09:30AM | Duration 17h10 | Departure days Thu, Fri | Cheapest price €63 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 11:50AM | Duration 18h45 | Departure days Everyday | Cheapest price €59 |
Operator FlixBus | Departure Time 07:29PM | Arrival Time 05:50PM | Duration 22h21 | Departure days Sun | Cheapest price €100 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 03:05PM | Duration 18h55 | Departure days Everyday | Cheapest price €40 |
Operator FlixBus | Departure Time 10:40PM | Arrival Time 05:50PM | Duration 19h10 | Departure days Mon, Sun | Cheapest price €63 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 05:50PM | Duration 18h50 | Departure days Everyday | Cheapest price €71 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 06:45PM | Duration 19h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €62 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 11:45PM | Duration 23h50 | Departure days Mon, Thu, Fri | Cheapest price €64 |
The table below shows live departures for Karlsruhe to Rome buses for today, Saturday, September 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:30 PM Karlsruhe Hbf | 18h35 | 7:05 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 5:05 PM Karlsruhe Hbf | 16h25 | 9:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 5:05 PM Karlsruhe Hbf | 19h10 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 8:10 PM Karlsruhe Hbf | 17h40 | 1:50 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:10 PM Karlsruhe Hbf | 18h55 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:00 PM Karlsruhe Hbf | 18h50 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 11:40 PM Karlsruhe Hbf | 19h05 | 6:45 PM Roma, Autostazione Tiburtina | 1 transfer | |
| Sunday, September 13 | |||||
FlixBus · FlixBus | 3:20 AM Karlsruhe Hbf | 17h50 | 9:10 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 4:55 AM Karlsruhe Hbf | 18h05 | 11:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 5:15 AM Karlsruhe Hbf | 18h25 | 11:40 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 11:05 AM Karlsruhe Hbf | 18h30 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 11:05 AM Karlsruhe Hbf | 19h00 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Rome run on average 12 times per day, taking around 17h 12m. Cheap bus tickets for this journey start at €39 but you can travel from only €25 by train.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 529 miles (852 km) distance in 15h 15m.
Distance 529 miles (852 km) |
Average bus duration 17h 12m |
Cheapest ticket price €39 |
Buses per day 12 |
Direct buses 1 |
Fastest bus 15h 15m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Sun |
Best time to book 21 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Karlsruhe to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Rome buses use the Karlsruhe Hbf to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Karlsruhe and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.
Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Here are some other resources that might have the information you need