The cheapest and fastest buses from Karlsruhe to Rome
Cheapest price
$89
Average price
$109
Fastest journey
17 h
Average duration
17 h 47 m
Buses per day
15
Distance
852 km
The best way to find a cheap bus ticket from Karlsruhe to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Rome will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $89.
Of the 15 buses that leave Karlsruhe for Rome on Sat, Mar 14, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 14 the direct buses cover the 852 km distance in an average of 17 h 47 m but if you time it right, some buses will get you there in just 17 h .
On Sat, Mar 14 the slowest buses will take 18 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixTrain+
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare bus and train for Karlsruhe to Rome
Omio recommends booking the bus as it is the most popular option from Karlsruhe to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $48. For those with little time consider booking a train which can get you there in 12h 28m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $48, and a train costs an average of $249.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$84 Average price Cheapest | $367 Average price |
22h 49m Average total duration 22h 19m Onboard + 30m Additional time* | 12h 58m Average total duration Fastest 12h 28m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Karlsruhe to Rome Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:20AM | Arrival Time 09:10PM | Duration 17h50 | Departure days Mon, Tue, Wed, Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 03:55AM | Arrival Time 11:00PM | Duration 19h05 | Departure days Mon, Tue | Cheapest price $71 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 11:00PM | Duration 18h05 | Departure days Sat | Cheapest price $107 |
Operator Marino Autolinee | Departure Time 09:30AM | Arrival Time 04:30AM | Duration 19h00 | Departure days Sat | Cheapest price $162 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 06:10AM | Duration 20h40 | Departure days Mon, Wed, Sat | Cheapest price $70 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 06:10AM | Duration 18h20 | Departure days Mon, Tue, Sat | Cheapest price $72 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 07:05AM | Duration 18h35 | Departure days Mon, Sat | Cheapest price $93 |
Operator FlixBus | Departure Time 02:23PM | Arrival Time 01:20PM | Duration 22h57 | Departure days Tue | Cheapest price $77 |
Operator FlixBus | Departure Time 03:29PM | Arrival Time 03:20PM | Duration 23h51 | Departure days Sat | Cheapest price $89 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 09:30AM | Duration 17h00 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $70 |
Operator FlixBus | Departure Time 07:29PM | Arrival Time 03:20PM | Duration 19h51 | Departure days Fri | Cheapest price $138 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 01:50PM | Duration 17h40 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $70 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 06:00PM | Duration 21h45 | Departure days Mon, Sat | Cheapest price $71 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 06:00PM | Duration 21h40 | Departure days Fri | Cheapest price $117 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 06:05PM | Duration 19h05 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $84 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 11:45PM | Duration 23h50 | Departure days Fri, Sat | Cheapest price $116 |
Live departures
Karlsruhe to Rome bus times
The table below shows live departures for Karlsruhe to Rome buses for today, Friday, March 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixTrain+ FlixBus · FlixBus | 6:29 PM Karlsruhe Hbf | 19h51 | 2:20 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixTrain+ FlixBus · FlixBus | 6:29 PM Karlsruhe Hbf | 22h31 | 5:00 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 7:10 PM Karlsruhe Hbf | 18h55 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 7:10 PM Karlsruhe Hbf | 17h40 | 12:50 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 7:20 PM Karlsruhe Hbf | 21h40 | 5:00 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 10:00 PM Karlsruhe Hbf | 19h05 | 5:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 10:55 PM Karlsruhe Hbf | 23h50 | 10:45 PM Roma, Autostazione Tiburtina | 1 transfer | |
| Saturday, March 14 | |||||
FlixBus · FlixBus | 2:20 AM Karlsruhe Hbf | 17h50 | 8:10 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 3:55 AM Karlsruhe Hbf | 18h05 | 10:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 8:30 AM Karlsruhe Hbf | 20h05 | 4:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 8:30 AM Karlsruhe Hbf | 20h35 | 5:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
254 · 055 | 8:30 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 19h00 | 3:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 10:50 AM Karlsruhe Hbf | 18h20 | 5:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 11:30 AM Karlsruhe Hbf | 18h35 | 6:05 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixTrain+ FlixBus · FlixBus | 2:29 PM Karlsruhe Hbf | 23h51 | 2:20 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus | 3:30 PM Karlsruhe Hbf | 17h00 | 8:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 3:30 PM Karlsruhe Hbf | 19h45 | 11:15 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Rome by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 14
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Mar 22
Mar 23
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Mar 27
Mar 28
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Apr 03
Why should you book Karlsruhe to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Karlsruhe to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlsruhe to Rome.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Karlsruhe to Rome.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlsruhe to Rome.
Journey information
Overview: Bus from Karlsruhe to Rome
Buses from Karlsruhe to Rome run on average 13 times per day, taking around 22h 19m. Cheap bus tickets for this journey start at $48 (€39) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 529 miles (852 km) distance in 17h 10m.
Distance 529 miles (852 km) |
Average bus duration 22h 19m |
Cheapest ticket price $48 (€39) |
Buses per day 13 |
Direct buses 1 |
Fastest bus 17h 10m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: FlixBus, BlaBlaCar Bus from Karlsruhe to RomeYou can travel by bus between Karlsruhe to Rome with FlixBus, BlaBlaCar Bus for as low as $48 (€39). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
FAQs: Bus from Karlsruhe to Rome
Find answers to the most common questions about traveling from Karlsruhe to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Karlsruhe to Rome
Most popular bus connections from Karlsruhe
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