- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Aug 29
$40
Average ticket price on Aug 29
$53
Fastest journey on Aug 29
7 h 50 m
Average journey duration on Aug 29
9 h 35 m
Buses on Aug 29
3
Distance
354 km
The best way to find a cheap bus ticket from Karlsruhe to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Brussels will cost around $53 if you buy it on the day, but the cheapest tickets can be found for only $40.
It's difficult to get from Karlsruhe to Brussels without transferring at least once.
51510 · 4743
FlixBus · FlixBus
FlixBus · FlixBus
51510 · 4743
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $49 For those with little time, consider booking a train, which has an average total journey time of 4h 5m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $49, while a train costs an average of $120.
Distance: 219 miles (354 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$49 Average price Cheapest | $120 Average price | $88 Average price (fuel + tolls) |
7h 13m Average total duration 6h 43m Onboard + 30m Additional time* | 4h 5m Average total duration Fastest 3h 35m Onboard + 30m Additional time* | 5h 30m Average total duration (door-to-door) |
0.4 - 0.9kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Brussels:
A bus is $71 less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $120.
Other travel options to Brussels take longer:
Bus takes on average 6h 43m.
Tickets start at around $49 compared to roughly $88 in fuel and tolls — a saving of about $39. The journey takes 6h 43m versus 5h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 12:25AM | Arrival Time 08:40AM | Duration 8h15 | Departure days Fri | Cheapest price $124 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 01:55PM | Duration 10h40 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $28 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 01:55PM | Duration 10h05 | Departure days Sat, Sun | Cheapest price $58 |
Operator BlaBlaCar | Departure Time 05:30AM | Arrival Time 10:20AM | Duration 4h50 | Departure days Fri | Cheapest price $37 |
Operator BlaBlaCar | Departure Time 08:25AM | Arrival Time 01:45PM | Duration 5h20 | Departure days Sun | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 02:30PM | Duration 5h20 | Departure days Fri | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 02:50PM | Duration 5h20 | Departure days Thu | Cheapest price $41 |
Operator BlaBlaCar | Departure Time 12:20PM | Arrival Time 05:40PM | Duration 5h20 | Departure days Tue | Cheapest price $35 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 03:25AM | Duration 10h50 | Departure days Fri, Sat | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 05:10PM | Arrival Time 10:00PM | Duration 4h50 | Departure days Tue | Cheapest price $42 |
Operator BlaBlaCar Bus | Departure Time 09:05PM | Arrival Time 04:55AM | Duration 7h50 | Departure days Thu, Fri, Sat, Sun | Cheapest price $40 |
The table below shows live departures for Karlsruhe to Brussels buses for today, Friday, August 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
51510 · 4743 | 9:05 PM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 7h50 | 4:55 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| Saturday, August 29 | |||||
FlixBus · FlixBus | 3:50 AM Karlsruhe Hbf | 10h05 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 4:35 PM Karlsruhe Hbf | 10h50 | 3:25 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Brussels run on average 3 times per day, taking around 6h 43m. Cheap bus tickets for this journey start at $28 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:35. The fastest bus covers the 219 miles (354 km) distance in 7h 35m.
Distance 219 miles (354 km) |
Average bus duration 6h 43m |
Cheapest ticket price $28 |
Buses per day 3 |
Direct buses 1 |
Fastest bus 7h 35m |
First bus 12:25 AM |
Last bus 11:35 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 14 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Karlsruhe to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Brussels buses use the Karlsruhe Hbf to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord). Use this guide to compare Karlsruhe and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.
Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
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