- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price
$51
Average price
$65
Fastest journey
7 h 35 m
Average duration
9 h 8 m
Buses per day
2
Distance
354 km
The best way to find a cheap bus ticket from Karlsruhe to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Brussels will cost around $65 if you buy it on the day, but the cheapest tickets can be found for only $51.
It's difficult to get from Karlsruhe to Brussels without transferring at least once.
FlixBus · FlixBus
30493 · 51095
30493 · 51095
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a train which can get you there in 3h 36m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $26, and a train costs an average of $53.
Distance: 219 miles (354 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$51 Average price Cheapest | $139 Average price | $86 Average price (fuel + tolls) |
7h 55m Average total duration 7h 25m Onboard + 30m Additional time* | 4h 6m Average total duration Fastest 3h 36m Onboard + 30m Additional time* | 5h 30m Average total duration (door-to-door) |
0.4 - 0.9kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Brussels:
A bus is $87 (€72) less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $139 (€114).
Other travel options to Brussels take longer:
Bus takes on average 7h 25m.
Tickets start at around $51 (€42) compared to roughly $86 (€71) in fuel and tolls — a saving of about $34 (€28). The journey takes 7h 25m versus 5h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 12:25AM | Arrival Time 08:00AM | Duration 7h35 | Departure days Tue, Wed, Thu, Fri | Cheapest price $73 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 01:55PM | Duration 10h40 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $42 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 01:55PM | Duration 10h05 | Departure days Sat, Sun | Cheapest price $65 |
Operator BlaBlaCar | Departure Time 04:10PM | Arrival Time 09:10PM | Duration 5h00 | Departure days Fri | Cheapest price $53 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 03:25AM | Duration 10h50 | Departure days Fri, Sat | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 10:30PM | Duration 5h00 | Departure days Fri | Cheapest price $48 |
Operator BlaBlaCar | Departure Time 06:40PM | Arrival Time 12:00AM | Duration 5h20 | Departure days Wed | Cheapest price $51 |
Operator BlaBlaCar Bus | Departure Time 09:05PM | Arrival Time 04:55AM | Duration 7h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $45 |
The table below shows live departures for Karlsruhe to Brussels buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
51510 · 4743 | 9:05 PM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 7h50 | 4:55 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
51510 · 4743 | 9:05 PM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 7h50 | 4:55 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| Wednesday, July 15 | |||||
30493 · 51095 | 12:25 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 7h35 | 8:00 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Karlsruhe Hbf | 10h40 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Karlsruhe to Brussels run on average 4 times per day, taking around 7h 25m. Cheap bus tickets for this journey start at $26 (€21) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:35. The fastest bus covers the 219 miles (354 km) distance in 7h 30m.
Distance 219 miles (354 km) |
Average bus duration 7h 25m |
Cheapest ticket price $26 (€21) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 7h 30m |
First bus 12:25 AM |
Last bus 11:35 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 49 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Karlsruhe to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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