Karlsruhe to Brussels bus with FlixBus

Sat, Aug 29
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BlaBlaCar Bus
BlaBlaCar
Alsa
Rede Expressos
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BlaBlaCar Bus
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Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from Karlsruhe to Brussels

Showing times, prices and bookable tickets for Aug 29

Cheapest price on Aug 29

$40

Average ticket price on Aug 29

$53

Fastest journey on Aug 29

7 h 50 m

Average journey duration on Aug 29

9 h 35 m

Buses on Aug 29

3

Distance

354 km

Cheap tickets

The best way to find a cheap bus ticket from Karlsruhe to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Karlsruhe to Brussels will cost around $53 if you buy it on the day, but the cheapest tickets can be found for only $40.

Fast buses

It's difficult to get from Karlsruhe to Brussels without transferring at least once.

  • BlaBlaCar Bus51510 · 4743
    9:05 PM7h50
    Karlsruhe, Hinterm Hauptbahnhof (Südeingang)
    4:55 AMBrussels, Brussels South (Gare du Midi)
    $401One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    4:35 PM10h50
    Karlsruhe Hbf
    3:25 AMBrussels, Brussels South (Gare du Midi)
    $551One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    3:50 AM10h05
    Karlsruhe Hbf
    1:55 PMBrussels, Brussels South (Gare du Midi)
    $641One-way
    1 transfer

Travel Information

Compare train and bus for Karlsruhe to Brussels

Omio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $49 For those with little time, consider booking a train, which has an average total journey time of 4h 5m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $49, while a train costs an average of $120.

Distance: 219 miles (354 km)

Compare bus with

Bus
Most popular
Train
Driving

$49

Average price

Cheapest

$120

Average price

$88

Average price

(fuel + tolls)

7h 13m

Average total duration

6h 43m

Onboard

+

30m

Additional time*

4h 5m

Average total duration

Fastest

3h 35m

Onboard

+

30m

Additional time*

5h 30m

Average total duration

(door-to-door)

0.4 - 0.9kg

CO2 emissions

0.1 - 0.3kg

CO2 emissions

Lowest

-

CO2 emissions

FlixBus

Most popular bus company

Deutsche Bahn

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Karlsruhe to Brussels is a bus with an average price of $49.

This is compared to other travel options from Karlsruhe to Brussels:

A bus is $71 less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $120.

The fastest way to travel from Karlsruhe to Brussels is by train with an average journey time of 3h 35m.

Other travel options to Brussels take longer:

Bus takes on average 6h 43m.

It's helpful to compare your options as there are 2 ways to travel between Karlsruhe and Brussels including taking a train and bus.
We recommend using the train as it is the most popular way to get from Karlsruhe to Brussels among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $49 compared to roughly $88 in fuel and tolls — a saving of about $39. The journey takes 6h 43m versus 5h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus, BlaBlaCar.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Karlsruhe to Brussels Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
BlaBlaCar Bus
Departure Time
12:25AM
Arrival Time
08:40AM
Duration
8h15
Departure days
Fri
Cheapest price
$124
Operator
FlixBus
Departure Time
03:15AM
Arrival Time
01:55PM
Duration
10h40
Departure days
Mon, Tue, Wed, Thu, Fri
Cheapest price
$28
Operator
FlixBus
Departure Time
03:50AM
Arrival Time
01:55PM
Duration
10h05
Departure days
Sat, Sun
Cheapest price
$58
Operator
BlaBlaCar
Departure Time
05:30AM
Arrival Time
10:20AM
Duration
4h50
Departure days
Fri
Cheapest price
$37
Operator
BlaBlaCar
Departure Time
08:25AM
Arrival Time
01:45PM
Duration
5h20
Departure days
Sun
Cheapest price
$36
Operator
BlaBlaCar
Departure Time
09:10AM
Arrival Time
02:30PM
Duration
5h20
Departure days
Fri
Cheapest price
$52
Operator
BlaBlaCar
Departure Time
09:30AM
Arrival Time
02:50PM
Duration
5h20
Departure days
Thu
Cheapest price
$41
Operator
BlaBlaCar
Departure Time
12:20PM
Arrival Time
05:40PM
Duration
5h20
Departure days
Tue
Cheapest price
$35
Operator
FlixBus
Departure Time
04:35PM
Arrival Time
03:25AM
Duration
10h50
Departure days
Fri, Sat
Cheapest price
$55
Operator
BlaBlaCar
Departure Time
05:10PM
Arrival Time
10:00PM
Duration
4h50
Departure days
Tue
Cheapest price
$42
Operator
BlaBlaCar Bus
Departure Time
09:05PM
Arrival Time
04:55AM
Duration
7h50
Departure days
Thu, Fri, Sat, Sun
Cheapest price
$40

Live departures

Karlsruhe to Brussels bus times

The table below shows live departures for Karlsruhe to Brussels buses for today, Friday, August 28. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
BlaBlaCar Bus51510 · 47439:05 PM Karlsruhe, Hinterm Hauptbahnhof (Südeingang)
7h50
4:55 AM Brussels, Brussels South (Gare du Midi)1 transfer
Saturday, August 29
FlixBusFlixBus · FlixBus3:50 AM Karlsruhe Hbf
10h05
1:55 PM Brussels, Brussels South (Gare du Midi)1 transfer
FlixBusFlixBus · FlixBus4:35 PM Karlsruhe Hbf
10h50
3:25 AM Brussels, Brussels South (Gare du Midi)1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Karlsruhe to Brussels by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Karlsruhe to Brussels buses with Omio?

FlixBus as well as BlaBlaCar Bus offer buses services from Karlsruhe to Brussels.
Omio is an official ticket reseller for all your travel options from Karlsruhe to Brussels.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Karlsruhe to Brussels.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Brussels.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Karlsruhe to Brussels.
  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Brussels.

Journey information

Overview: Bus from Karlsruhe to Brussels

GermanyGermany
BelgiumBelgium
Icon of bus

Buses from Karlsruhe to Brussels run on average 3 times per day, taking around 6h 43m. Cheap bus tickets for this journey start at $28 if you book in advance.

There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:35. The fastest bus covers the 219 miles (354 km) distance in 7h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
219 miles (354 km)
Average bus duration
6h 43m
Cheapest ticket price
$28
Buses per day
3
Direct buses
1
Fastest bus
7h 35m
First bus
12:25 AM
Last bus
11:35 PM
Cheapest Month
Sep
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Jan - Mar
Busiest Day
Mon
Least Busy Day
Sun
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, BlaBlaCar Bus, BlaBlaCar from Karlsruhe to BrusselsYou can travel by bus between Karlsruhe to Brussels with FlixBus, BlaBlaCar Bus, BlaBlaCar for as low as $28. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
7h 35m
Cheapest FlixBus Price
$28
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

BlaBlaCar Bus

About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average BlaBlaCar Bus Duration
7h 35m
Cheapest BlaBlaCar Bus Price
$34
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.

BlaBlaCar

About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
1 a day

Complete guide to Brussels

Things to do in Brussels

Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.

  • Must visit

Royal Museums of Fine Arts of Belgium

Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.

  • Must visit

Magritte Museum

Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.

  • Must visit

Comics Art Museum

Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.

Euro (€)

Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.

Average meal costs

Budget
€8-15 for fast food or casual takeaway.
Mid-range
€20-35 per person for a standard restaurant meal.
Fine dining
€70+ per person for upscale restaurants.
Coffee
€3-5 for cappuccino or latte.

Tipping culture

Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.

FAQs: Bus from Karlsruhe to Brussels

Find answers to the most common questions about traveling from Karlsruhe to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Karlsruhe to Brussels can start from as little as $28 when you book in advance. The average bus ticket price for Karlsruhe to Brussels is $49 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Karlsruhe to Brussels is 7h 35m to travel the 219 miles (354 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Karlsruhe to Brussels leaves at 12:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Karlsruhe to Brussels leaves at 11:35 PM.
Yes, there are 1 direct buses a day from Karlsruhe to Brussels with FlixBus, BlaBlaCar. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Karlsruhe to Brussels, you can count on FlixBus, BlaBlaCar Bus, BlaBlaCar for the best way to get you to Brussels. You can also check all possible bus companies who offer a service between Karlsruhe and Brussels and compare the amenities they offer before buying a bus ticket.
A trip to Brussels from Karlsruhe is worth doing but not as a day trip with a journey time of 7h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Karlsruhe to Brussels is September.
It's helpful to compare your options as there are 2 ways to travel between Karlsruhe and Brussels including taking a train and bus.
Yes, there are bathrooms on board the bus from Karlsruhe to Brussels for bus company FlixBus, BlaBlaCar Bus.
Yes, the following accessibility options are available when taking the bus from Karlsruhe to Brussels:
  • BlaBlaCar Bus
    • Assistance
    • Priority boarding
    • Accessible seating options.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Brussels are:
  • Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
  • Atomium, an iconic structure and museum offering panoramic views of the city
  • Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
  • Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
  • Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
The best things to do in Brussels include:
  • Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
  • Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
  • Sample Belgian chocolates at one of the city's renowned chocolatiers
  • Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
  • Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
Whether you can cancel your bus ticket from Karlsruhe to Brussels depends on the bus companies:
  • BlaBlaCar Bus
    • You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Karlsruhe to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Karlsruhe to Brussels:
  • BlaBlaCar Bus
    • One carry-on bag up to 7kg and one checked bag up to 20kg.
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Karlsruhe to Brussels:
  • BlaBlaCar Bus
    • Additional luggage can be purchased for a fee.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Karlsruhe to Brussels. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Karlsruhe to Brussels with the following bus company: FlixBus, BlaBlaCar Bus
Yes, there are USB plugs on board the bus from Karlsruhe to Brussels with the following bus company: FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the bus from Karlsruhe to Brussels with the following bus company: FlixBus, BlaBlaCar Bus.
Since both Karlsruhe and Brussels are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the train as it is the most popular way to get from Karlsruhe to Brussels among Omio's users.
Belgium uses the euro (EUR) as its currency. Travelers generally find card payments widely accepted in cities, restaurants, and shops, though carrying some cash is advisable for small purchases or in rural areas.
In Brussels, travelers should be cautious of pickpocketing, especially in crowded areas like Grand Place, public transport, and popular tourist sites. Common scams include distraction techniques and fake petitions. It's advisable to stay vigilant, avoid displaying expensive items, and use official taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Karlsruhe to Brussels

Most Karlsruhe to Brussels buses use the Karlsruhe Hbf to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord). Use this guide to compare Karlsruhe and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Karlsruhe
Arrival bus stations in Brussels
Karlsruhe Hbf
City-centre transport

Getting to Karlsruhe Hbf from Karlsruhe city centre

Train74346, 80700, 80702, 80704, 80706, 80708, 84704, 84710, 84714, 84722, 84726, 84740, 84746, 84752, 84758, 84764, 84770, 84776, 84782, 84788, 84792, 84794, 84796, 84800, 84808, 84810, 84814, 84816, 84859, 84864, 84866, 84868, 84870, 84872, 84876, 84877, 84878, 84880, 84882, 84884, 84886, 84888, 84890, 84892, 84894, 84896, 84898, 84900, 84902, 84904, 84906, 84908, 84910, 84912, 84913, 84914, 84916, 84918, 84920, 84922, 84924, 84926, 84928, 84930, 84931, 84934, 84935, 84936, 84938, 84940, 84941, 84944, 84946, 84948, 84952, 84956, 84958, 84962, 84964, 84968, 84972, 84976, 84980, 84984, 84986, 84988, 84994, 84998, 85000, 85004, 85006, 85008, 85012, 85014, 85018, 85020, 85022, 85024, 85026, 85030, 85032, 85034, 85040, 85042, 85046, 85052, 85054, 85056, 85058, 85060, 85064, 85068, 85070, 85074, 85078, 85082, 85084, 85086, 85088, 85090, 85178, 85278, 85311, 85390, 85392, 85396, 85400, 85402, 85404, 85406, 85408, 85410, 85412, 85414, 85416, 85418, 85420, 85422, 85424, 85426, 85428, 85430, 85432, 85434, 85436, 85438, 85440, 85442, 85444, 85446, 85448, 85450, 85452, 85454, 85456, 85458, 85460, 85462, 85466, 85468, 85470, 85474, 85476, 85478, 85480, 85482, 85484, 85488, 85500, 85502, 85504, 85506, 85508, 85510, 85512, 85514, 85516, 85518, 85520, 85522, 85524, 85526, 85528, 85530, 85532, 85534, 85536, 85538, 85540, 85546, 85548, 85551, 85557, 85559, 85561, 85563, 85565, 85567, 85569, 85571, 85573, 85575, 85577, 85579, 85581, 85583, 85585, 85589, 85591, 85597, 85599, 85605, 85607, 85611, 85615, 85619, 85623, 85629, 85631, 85633, 85635, 85639, 85641, 85645, 85647, 85651, 85653, 85655, 85659, 85661, 85665, 85669, 85673, 85675, 85679, 85681, 85685, 85687, 85689, 85821, 85916, 85918, 85922, 85932, 85936, 85938, 85940, 85942, 85946, 85948, 85950, 85952, 85954, 85956, 85958, 85960, 85962, 85964, 85966, 85968, 85970, 85972, 85974, 85976 · 6m · every ~10 min
Tram2, Nl2 · 6m · every ~11 min
Karlsruhe, Hinterm Hauptbahnhof (Südeingang)Karlsruhe Hauptbahnhof, 76137 Karlsruhe, GermanyWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Karlsruhe, Hinterm Hauptbahnhof (Südeingang) from Karlsruhe city centre

Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:

Tram2, Nl2 · 1m · every ~11 min

Karlsruhe, Hinterm Hauptbahnhof (Südeingang) bus station facilities and services

Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).

Tickets and information

Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).

Parking, taxis and toilets

Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.

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