- Must visit
National Museum
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
We are not able to find a bus between these two places.
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Omio recommends booking the flight as it is the most popular option from Florence to Prague among Omio's users. If you are prioritising price take the train with prices starting from $38. For those with little time consider booking a flight which can get you there in 2h 35m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.9kg. The ticket price range depends on the travel mode: a train costs an average of $38, and a flight costs an average of $23.
Distance: 461 miles (743 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$92 Average price | $199 Average price | $38 Average price Cheapest | $268 Average price (fuel + tolls) |
21h 10m Average total duration 20h 40m Onboard + 30m Additional time* | 5h 35m Average total duration Fastest 2h 35m Onboard + 3h 0m Additional time* | 13h 21m Average total duration 12h 51m Onboard + 30m Additional time* | 11h 6m Average total duration (door-to-door) |
0.7 - 1.9kg CO2 emissions Lowest | 2.2 - 4.5kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Prague:
A train is $54 (€44) less than a bus for this route with tickets for a bus from Florence to Prague costing on average $92 (€75).
A train is $161 (€132) less than a flight for this route with tickets for a flight from Florence to Prague costing on average $199 (€163).
Other travel options to Prague take longer:
Train takes on average 12h 51m.
Bus takes on average 20h 40m.
Tickets start at around $92 (€75) compared to roughly $268 (€220) in fuel and tolls — a saving of about $176 (€145). The journey takes 20h 40m versus 11h 6m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 08:55PM | Duration 20h40 | Departure days Thu | Cheapest price $112 |
Operator FlixBus | Departure Time 12:30AM | Arrival Time 05:30PM | Duration 17h00 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 12:55AM | Arrival Time 07:10PM | Duration 18h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 08:05PM | Duration 19h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 01:30AM | Arrival Time 08:05PM | Duration 18h35 | Departure days Tue, Wed | Cheapest price $100 |
Operator FlixBus | Departure Time 02:15AM | Arrival Time 10:15PM | Duration 20h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $108 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 02:25AM | Duration 21h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $122 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 02:50AM | Duration 21h30 | Departure days Wed, Fri, Sat, Sun | Cheapest price $143 |
Operator FlixBus | Departure Time 09:50AM | Arrival Time 03:15AM | Duration 17h25 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 05:45AM | Duration 18h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 07:55AM | Duration 20h05 | Departure days Thu | Cheapest price $100 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 05:45AM | Duration 17h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 07:30AM | Duration 18h40 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $100 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 10:35AM | Duration 20h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 11:45AM | Duration 20h55 | Departure days Thu | Cheapest price $89 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 07:25AM | Duration 15h05 | Departure days Thu | Cheapest price $79 |
Operator RegioJet a.s. | Departure Time 04:45PM | Arrival Time 09:10AM | Duration 16h25 | Departure days Wed, Sun | Cheapest price $85 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 01:20PM | Duration 19h50 | Departure days Thu, Fri | Cheapest price $86 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 01:30PM | Duration 19h15 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 06:20PM | Arrival Time 12:45PM | Duration 18h25 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 06:25PM | Arrival Time 11:45AM | Duration 17h20 | Departure days Thu | Cheapest price $103 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 06:05PM | Duration 21h45 | Departure days Thu | Cheapest price $133 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 01:55PM | Duration 17h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $93 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 06:05PM | Duration 20h25 | Departure days Thu | Cheapest price $123 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 05:35PM | Duration 19h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $99 |
Operator FlixBus | Departure Time 10:20PM | Arrival Time 08:05PM | Duration 21h45 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $105 |
Operator FlixBus | Departure Time 10:40PM | Arrival Time 08:30PM | Duration 21h50 | Departure days Thu | Cheapest price $109 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 08:15PM | Duration 20h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $104 |
The table below shows live departures for Florence to Prague buses for tomorrow, Friday, July 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 AM Florence | 18h30 | 3:45 AM Prague | 0 transfersDirect | |
![]() | 10:50 AM Florence | 20h05 | 6:55 AM Prague | 0 transfersDirect | |
![]() | 4:20 PM Florence | 15h05 | 7:25 AM Prague | 0 transfersDirect | |
![]() | 5:30 PM Florence | 14h55 | 8:25 AM Prague | 0 transfersDirect | |
![]() | 6:25 PM Florence | 17h20 | 11:45 AM Prague | 0 transfersDirect | |
![]() | 7:30 PM Florence | 17h10 | 12:40 PM Prague | 0 transfersDirect | |
![]() | 8:20 PM Florence | 21h45 | 6:05 PM Prague | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence to Prague run on average 34 times per day, taking around 20h 40m. Cheap bus tickets for this journey start at $65 (€54) but you can travel from only $23 (€19) by flight.
There are 3 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 461 miles (743 km) distance in 14h 55m.
Distance 461 miles (743 km) |
Average bus duration 20h 40m |
Cheapest ticket price $65 (€54) |
Buses per day 34 |
Direct buses 3 |
Fastest bus 14h 55m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 77 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
One of Prague’s most significant museum institutions, preserving Jewish history through synagogues, exhibitions, and the Old Jewish Cemetery.
A leading city gallery in a Gothic landmark on Old Town Square, hosting major modern and contemporary art exhibitions.
Prague’s historic heart, surrounded by major monuments and lively at all times of day; essential for first-time visitors.
A picturesque Baroque district below Prague Castle with quiet lanes, embassies, gardens, and classic city charm.
A major boulevard-like square central to modern Czech history, shopping, and the city’s urban energy.
Marinated beef sirloin with a creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the most iconic Czech Sunday and festive dishes.
Roast pork served with bread dumplings and braised sauerkraut. This is a classic Czech pub and home-style meal strongly associated with Bohemian cooking.
Czech goulash is a rich beef stew seasoned with onion and paprika, usually served with bread dumplings. It is a staple of traditional Prague taverns and beer halls.
A Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients, tasting menus, and a sophisticated modern atmosphere.
An elegant grand café offering refined Czech and Central European dishes, excellent breakfasts, and classic pastries in a beautifully restored interior.
A well-regarded Old Town restaurant focused on updated Czech cuisine, including svíčková and goulash, in a polished but approachable setting.
Moderate for Europe: beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip is expected for fast food, but small change is appreciated in cafés.
Official public transport app
Praha Hlavní Nádraží, Prague -> Staroměstské Náměstí, Prague
Find answers to the most common questions about traveling from Florence to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Florence to Prague buses use the Scandicci, Villa Costanza (Firenze) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Florence and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Scandicci, Villa Costanza (Firenze) is 1 km from Florence city centre. Public transport options include:
Scandicci, Villa Costanza (Firenze) has practical services for this route, including Wifi, Parking, ATM, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located near the entrance.
Ticket office support is available at Scandicci, Villa Costanza (Firenze).
Available at Scandicci, Villa Costanza (Firenze): Parking, WC.
Accessibility facilities are available at Scandicci, Villa Costanza (Firenze): Elevators, ramps.
Firenze, Piazzale Montelungo is 1 km from Florence city centre. Public transport options include:
Firenze, Piazzale Montelungo has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located near the entrance.
Ticket office support is available at Firenze, Piazzale Montelungo.
Available at Firenze, Piazzale Montelungo: Parking, Taxis, WC.
Accessibility facilities are available at Firenze, Piazzale Montelungo: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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