The cheapest and fastest buses from Frankfurt am Main to Prague
Cheapest price
$37
Average price
$54
Fastest journey
6 h 15 m
Average duration
6 h 36 m
Buses per day
28
Distance
409 km
The best way to find a cheap bus ticket from Frankfurt am Main to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Prague will cost around $54 if you buy it on the day, but the cheapest tickets can be found for only $37.
Of the 28 buses that leave Frankfurt am Main for Prague on Thu, Mar 19, 13 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Mar 19 the direct buses cover the 409 km distance in an average of 6 h 36 m but if you time it right, some buses will get you there in just 6 h 15 m .
On Thu, Mar 19 the slowest buses will take 6 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
(Amsterdam -> Prague)
FlixBus
(Amsterdam -> Prague)
(Amsterdam -> Prague)
(Amsterdam -> Prague)
(Amsterdam -> Prague)
FlixBusTravel Information
Compare train, bus, and flight for Frankfurt am Main to Prague
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $14. For those with little time consider booking a flight which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $14, and a flight costs an average of $161.
Distance: 254 miles (409 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$43 Average price Cheapest | $108 Average price | $257 Average price |
7h 45m Average total duration 7h 15m Onboard + 30m Additional time* | 6h 2m Average total duration 5h 32m Onboard + 30m Additional time* | 6h 19m Average total duration Fastest 3h 19m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Frankfurt am Main to Prague Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 10:10AM | Duration 9h50 | Departure days Sat | Cheapest price $65 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 10:05AM | Duration 9h00 | Departure days Fri, Sat | Cheapest price $52 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 09:20AM | Duration 8h05 | Departure days Everyday | Cheapest price $39 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 11:30AM | Duration 9h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $57 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 09:20AM | Duration 7h30 | Departure days Everyday | Cheapest price $36 |
Operator FlixBus | Departure Time 02:45AM | Arrival Time 12:45PM | Duration 10h00 | Departure days Mon, Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 01:30PM | Duration 9h10 | Departure days Mon, Tue, Sat, Sun | Cheapest price $39 |
Operator BlaBlaCar | Departure Time 05:20AM | Arrival Time 10:40AM | Duration 5h20 | Departure days Fri | Cheapest price $50 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 01:30PM | Duration 7h25 | Departure days Mon, Tue, Sat, Sun | Cheapest price $32 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 03:40PM | Duration 9h30 | Departure days Wed, Thu, Fri, Sat | Cheapest price $43 |
Operator FlixBus | Departure Time 07:58AM | Arrival Time 05:40PM | Duration 9h42 | Departure days Sat | Cheapest price $44 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 05:35PM | Duration 8h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 09:58AM | Arrival Time 07:40PM | Duration 9h42 | Departure days Everyday | Cheapest price $44 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 07:10PM | Duration 8h30 | Departure days Everyday | Cheapest price $31 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 07:10PM | Duration 7h55 | Departure days Everyday | Cheapest price $31 |
Operator FlixBus | Departure Time 11:58AM | Arrival Time 09:40PM | Duration 9h42 | Departure days Mon, Fri, Sat | Cheapest price $44 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 09:10PM | Duration 8h10 | Departure days Everyday | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 01:20PM | Arrival Time 06:40PM | Duration 5h20 | Departure days Fri | Cheapest price $53 |
Operator FlixBus | Departure Time 01:58PM | Arrival Time 11:55PM | Duration 9h57 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $52 |
Operator FlixBus | Departure Time 02:03PM | Arrival Time 11:10PM | Duration 9h07 | Departure days Sat, Sun | Cheapest price $44 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 09:50PM | Duration 7h00 | Departure days Fri | Cheapest price $44 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 10:20PM | Duration 7h00 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $32 |
Operator FlixBus | Departure Time 03:58PM | Arrival Time 01:40AM | Duration 9h42 | Departure days Tue, Thu, Fri, Sun | Cheapest price $47 |
Operator Infobus | Departure Time 04:00PM | Arrival Time 11:30PM | Duration 7h30 | Departure days Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 12:25AM | Duration 7h20 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $32 |
Operator KLR | Departure Time 05:05PM | Arrival Time 07:50AM | Duration 14h45 | Departure days Wed, Fri | Cheapest price $31 |
Operator KLR | Departure Time 05:30PM | Arrival Time 07:50AM | Duration 14h20 | Departure days Wed, Fri | Cheapest price $31 |
Operator FlixBus | Departure Time 05:58PM | Arrival Time 03:30AM | Duration 9h32 | Departure days Fri, Sun | Cheapest price $47 |
Operator Regiojet | Departure Time 10:00PM | Arrival Time 04:48AM | Duration 6h48 | Departure days Everyday | Cheapest price $32 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 07:30AM | Duration 9h30 | Departure days Fri, Sat, Sun | Cheapest price $43 |
Operator Regiojet | Departure Time 10:30PM | Arrival Time 04:45AM | Duration 6h15 | Departure days Everyday | Cheapest price $32 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 06:55AM | Duration 7h25 | Departure days Everyday | Cheapest price $33 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 06:55AM | Duration 6h56 | Departure days Everyday | Cheapest price $32 |
Live departures
Frankfurt am Main to Prague bus times
The table below shows live departures for Frankfurt am Main to Prague buses for today, Wednesday, March 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 12:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h10 | 8:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 12:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h30 | 8:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 2:20 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h00 | 9:20 PM Praha, ÚAN Florenc | 0 transfersDirect | |
439п | 4:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 14h45 | 6:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
439п | 4:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 14h20 | 6:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
(Amsterdam -> Prague) | 9:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h48 | 3:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
(Amsterdam -> Prague) | 9:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h45 | 3:45 AM Prague, Central Train Station | 0 transfersDirect | |
(Amsterdam -> Prague) | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h15 | 3:45 AM Prague, Central Train Station | 0 transfersDirect | |
(Amsterdam -> Prague) | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h18 | 3:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 10:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 7h25 | 5:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h35 | 9:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 10:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h56 | 5:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
| Thursday, March 19 | |||||
FlixBus · FlixBus | 12:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h05 | 8:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 12:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h15 | 10:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h50 | 9:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 12:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h50 | 10:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h30 | 8:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 12:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h15 | 9:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 5:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h30 | 2:40 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h50 | 3:00 PM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 8:58 AM Frankfurt South station | 9h42 | 6:40 PM Praha, ÚAN Florenc | 1 transfer | |
FlixTrain+ FlixBus | 8:58 AM Frankfurt South station | 10h02 | 7:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 9:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h30 | 6:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 9:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h55 | 6:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 10:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h55 | 6:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 10:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h20 | 6:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Apr 07
Why should you book Frankfurt am Main to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of KLR, Infobus or BlaBlaCar Bus to find the best option for your trip from Frankfurt am Main to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main to Prague.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of KLR, Infobus or BlaBlaCar Bus to find the best option for your trip from Frankfurt am Main to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main to Prague.
Journey information
Overview: Bus from Frankfurt am Main to Prague
Buses from Frankfurt am Main to Prague run on average 29 times per day, taking around 7h 15m. Cheap bus tickets for this journey start at $14 (€12) if you book in advance.
There are 14 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 254 miles (409 km) distance in 6h 18m.
Distance 254 miles (409 km) |
Average bus duration 7h 15m |
Cheapest ticket price $14 (€12) |
Buses per day 29 |
Direct buses 14 |
Fastest bus 6h 18m |
First bus 00:05 |
Last bus 23:50 |
Bus providers: FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar from Frankfurt am Main to PragueYou can travel by bus between Frankfurt am Main to Prague with FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar for as low as $14 (€12). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
KLR
BlaBlaCar
Bus from Frankfurt am Main to Prague
There is only one provider for travel connections by bus from Frankfurt am Main to Prague. There are different departure possibilities in the morning, in the evening and at night. All connections include a changeover. The shortest route measures, including change time, a total travel time of 9 hours.
Which long-distance bus companies travel from Frankfurt am Main to Prague?
In regular service only FlixBus currently operates the route Frankfurt am Main - Prague.
How long does the bus journey from Frankfurt am Main to Prag take?
The shortest route starts at 8.5 am and reaches Nuremberg after 3 hours 20 minutes. After a change-over time of 1.55 hours, the journey continues for 3.35 hours to the destination Praha Nakníecí. This route is the fastest with a total travel time of 9 hours.
How often can you take the bus from Frankfurt am Main to Prague?
Apart from the departure time in the morning at 8.5 further travel possibilities exist at 20.5 over Regensburg with a total travel time of 9.55 hours and at 0.35 with a change in Leipzig and a total travel time of 10.5 hours.
Bus stations on the route Frankfurt am Main - Prague
At which bus station does the long-distance bus depart from in Frankfurt am Main? The long-distance bus company FlixBus starts with all bus lines in Frankfurt am Main from the central bus station, ZOB for short, at Frankfurt main station.
At which bus station does the long-distance bus arrive in Prague? After the bus line, FlixBus in Prague will take you to different destinations. They are. Praha Hradčanská Praha Nakníecí, ÚAN Florence, Hlavní Nádraí. There are good transport connections from all places of arrival.
FAQs: Bus from Frankfurt am Main to Prague
Find answers to the most common questions about traveling from Frankfurt am Main to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- KLR
- No refunds are allowed
- changes can be made with a fee if done at least 96 hours before departure.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- KLR
- Each passenger is allowed one checked bag with a maximum weight of 20 kg and one personal bag free of charge.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- KLR
- Additional luggage is subject to extra fees based on weight and size.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Frankfurt am Main to Prague
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Prague
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