- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$39
Average price
$46
Fastest journey
6 h 18 m
Average duration
6 h 55 m
Buses per day
35
Distance
409 km
The best way to find a cheap bus ticket from Frankfurt am Main to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Prague will cost around $46 if you buy it on the day, but the cheapest tickets can be found for only $39.
Of the 35 buses that leave Frankfurt am Main for Prague on Wed, Jun 17, 16 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 17 the direct buses cover the 409 km distance in an average of 6 h 55 m but if you time it right, some buses will get you there in just 6 h 18 m .
On Wed, Jun 17 the slowest buses will take 7 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
(Amsterdam -> Prague)
FlixBus
FlixBus
FlixBus
FlixBusOmio recommends booking the train as it is the most popular option from Frankfurt am Main to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $15. For those with little time consider booking a flight which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $15, and a flight costs an average of $178.
Distance: 254 miles (409 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$44 Average price Cheapest | $117 Average price | $282 Average price | $113 Average price (fuel + tolls) |
7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 6h 32m Average total duration 6h 2m Onboard + 30m Additional time* | 6h 19m Average total duration Fastest 3h 19m Onboard + 3h 0m Additional time* | 5h 38m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Prague:
A bus is $73 (€60) less than a train for this route with tickets for a train from Frankfurt am Main to Prague costing on average $117 (€95).
A bus is $238 (€193) less than a flight for this route with tickets for a flight from Frankfurt am Main to Prague costing on average $282 (€228).
Other travel options to Prague take longer:
Train takes on average 6h 2m.
Bus takes on average 7h 6m.
Tickets start at around $44 (€36) compared to roughly $113 (€92) in fuel and tolls — a saving of about $69 (€56). The journey takes 7h 6m versus 5h 38m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 11:20AM | Duration 10h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $44 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 11:30AM | Duration 9h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 10:05AM | Duration 8h15 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 02:45AM | Arrival Time 12:45PM | Duration 10h00 | Departure days Mon, Thu, Fri | Cheapest price $39 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 01:30PM | Duration 9h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 04:50AM | Arrival Time 12:45PM | Duration 7h55 | Departure days Sat, Sun | Cheapest price $44 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 01:30PM | Duration 7h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 07:58AM | Arrival Time 05:40PM | Duration 9h42 | Departure days Mon, Fri, Sat, Sun | Cheapest price $52 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 05:35PM | Duration 8h35 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 09:58AM | Arrival Time 08:00PM | Duration 10h02 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $44 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 07:10PM | Duration 8h30 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 07:35PM | Duration 8h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 11:58AM | Arrival Time 09:40PM | Duration 9h42 | Departure days Mon, Wed, Sat, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 09:10PM | Duration 8h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 01:58PM | Arrival Time 11:55PM | Duration 9h57 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $44 |
Operator FlixBus | Departure Time 02:03PM | Arrival Time 11:10PM | Duration 9h07 | Departure days Mon, Wed | Cheapest price $45 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 10:55PM | Duration 8h40 | Departure days Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 03:20PM | Arrival Time 10:20PM | Duration 7h00 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 03:58PM | Arrival Time 01:40AM | Duration 9h42 | Departure days Thu, Fri, Sun | Cheapest price $46 |
Operator Infobus | Departure Time 04:00PM | Arrival Time 11:30PM | Duration 7h30 | Departure days Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 12:05AM | Duration 7h00 | Departure days Everyday | Cheapest price $35 |
Operator KLR | Departure Time 05:30PM | Arrival Time 07:50AM | Duration 14h20 | Departure days Tue, Wed, Fri | Cheapest price $42 |
Operator FlixBus | Departure Time 05:58PM | Arrival Time 03:30AM | Duration 9h32 | Departure days Thu | Cheapest price $47 |
Operator BlaBlaCar | Departure Time 06:10PM | Arrival Time 11:40PM | Duration 5h30 | Departure days Thu | Cheapest price $57 |
Operator KLR | Departure Time 06:30PM | Arrival Time 07:50AM | Duration 13h20 | Departure days Mon, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 07:30AM | Duration 9h30 | Departure days Everyday | Cheapest price $39 |
Operator RegioJet a.s. | Departure Time 10:30PM | Arrival Time 04:48AM | Duration 6h18 | Departure days Everyday | Cheapest price $37 |
Operator BlaBlaCar | Departure Time 11:00PM | Arrival Time 04:40AM | Duration 5h40 | Departure days Wed | Cheapest price $43 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 08:55AM | Duration 9h25 | Departure days Everyday | Cheapest price $35 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 06:55AM | Duration 6h56 | Departure days Everyday | Cheapest price $38 |
The table below shows live departures for Frankfurt am Main to Prague buses for today, Tuesday, June 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
439п | 5:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 14h20 | 7:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h30 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
(Amsterdam -> Prague) | 10:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h18 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h25 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 7h25 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 11:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h56 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h56 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
| Wednesday, June 17 | |||||
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h15 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h50 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h05 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h05 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h50 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h15 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h30 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h30 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h10 | 1:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 6:05 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h25 | 1:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 6:05 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h55 | 4:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h55 | 5:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h35 | 5:35 PM Praha, M. Horákové (Hradčanská) | 0 transfersDirect | |
FlixTrain+ FlixBus | 9:58 AM Frankfurt South station | 10h02 | 8:00 PM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 9:58 AM Frankfurt South station | 9h12 | 7:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h55 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h30 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h55 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h20 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus | 11:58 AM Frankfurt South station | 9h42 | 9:40 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 1:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h10 | 9:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 1:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h30 | 9:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus | 1:58 PM Frankfurt South station | 9h57 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 2:03 PM Frankfurt South station | 8h52 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixTrain+ FlixBus | 2:03 PM Frankfurt South station | 9h07 | 11:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 3:20 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h00 | 10:20 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 5:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h00 | 12:05 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 5:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h20 | 12:25 AM Prague, Central Train Station | 0 transfersDirect | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main to Prague run on average 30 times per day, taking around 7h 6m. Cheap bus tickets for this journey start at $15 (€13) if you book in advance.
There are 14 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 254 miles (409 km) distance in 6h 15m.
Distance 254 miles (409 km) |
Average bus duration 7h 6m |
Cheapest ticket price $15 (€13) |
Buses per day 30 |
Direct buses 14 |
Fastest bus 6h 15m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 84 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
A significant museum complex preserving Jewish history and heritage through synagogues, ceremonial objects, and exhibitions in Josefov.
A highly regarded design museum with glass, ceramics, fashion, graphics, and decorative arts in a historic building near the Old Town.
Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
Established traditional restaurant known for duck, old-Bohemian recipes, and elegant historic interiors. A strong choice for a refined Czech meal.
Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
A famous modern Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively central setting.
Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Praha Hlavní Nádraží, Prague -> Václavské Náměstí, Prague
There is only one provider for travel connections by bus from Frankfurt am Main to Prague. There are different departure possibilities in the morning, in the evening and at night. All connections include a changeover. The shortest route measures, including change time, a total travel time of 9 hours.
In regular service only FlixBus currently operates the route Frankfurt am Main - Prague.
The shortest route starts at 8.5 am and reaches Nuremberg after 3 hours 20 minutes. After a change-over time of 1.55 hours, the journey continues for 3.35 hours to the destination Praha Nakníecí. This route is the fastest with a total travel time of 9 hours.
Apart from the departure time in the morning at 8.5 further travel possibilities exist at 20.5 over Regensburg with a total travel time of 9.55 hours and at 0.35 with a change in Leipzig and a total travel time of 10.5 hours.
At which bus station does the long-distance bus depart from in Frankfurt am Main? The long-distance bus company FlixBus starts with all bus lines in Frankfurt am Main from the central bus station, ZOB for short, at Frankfurt main station.
At which bus station does the long-distance bus arrive in Prague? After the bus line, FlixBus in Prague will take you to different destinations. They are. Praha Hradčanská Praha Nakníecí, ÚAN Florence, Hlavní Nádraí. There are good transport connections from all places of arrival.
Find answers to the most common questions about traveling from Frankfurt am Main to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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