- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
The best way to find a cheap bus ticket from Frankfurt am Main to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Prague will cost around $74 if you buy it on the day, but the cheapest tickets can be found for only $50.
On Fri, Oct 30, we found 37 buses from Frankfurt am Main to Prague, including 15 direct services.
On Fri, Oct 30 the direct buses cover the 409 km distance in an average of 6 h 58 m but if you time it right, some buses will get you there in just 6 h 18 m .
On Fri, Oct 30 the slowest buses will take 7 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Buses from Frankfurt am Main to Prague run on average 27 times per day, taking around 7h 55m. Cheap bus tickets for this journey start at $3 if you book in advance.
There are 13 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 254 miles (409 km) distance in 5h 40m.
Distance 254 miles (409 km) |
Average bus duration 7h 55m |
Cheapest ticket price $3 |
Buses per day 27 |
Direct buses 13 |
Fastest bus 5h 40m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 91 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Frankfurt am Main to Prague.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 10:10AM | Duration 9h50 | Departure days Fri, Sat | Cheapest price $71 |
Operator BlaBlaCar | Departure Time 12:20AM | Arrival Time 05:30AM | Duration 5h10 | Departure days Fri | Cheapest price $56 |
Operator FlixBus | Departure Time 01:05AM | Arrival Time 10:35AM | Duration 9h30 | Departure days Fri, Sat | Cheapest price $65 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 09:20AM | Duration 8h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 01:40AM | Arrival Time 11:30AM | Duration 9h50 | Departure days Mon, Fri, Sat, Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 10:05AM | Duration 8h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 02:45AM | Arrival Time 12:45PM | Duration 10h00 | Departure days Mon, Fri | Cheapest price $49 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 12:45PM | Duration 8h25 | Departure days Mon, Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 04:50AM | Arrival Time 12:45PM | Duration 7h55 | Departure days Sat, Sun | Cheapest price $71 |
Operator BlaBlaCar | Departure Time 05:50AM | Arrival Time 11:00AM | Duration 5h10 | Departure days Tue | Cheapest price $49 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 10:50AM | Duration 4h50 | Departure days Fri, Sat | Cheapest price $42 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 03:40PM | Duration 9h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 07:58AM | Arrival Time 05:40PM | Duration 9h42 | Departure days Mon, Sat | Cheapest price $108 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 01:20PM | Duration 5h20 | Departure days Fri | Cheapest price $54 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 05:55PM | Duration 8h55 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $42 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 02:50PM | Duration 5h40 | Departure days Sat | Cheapest price $45 |
Operator BlaBlaCar | Departure Time 09:40AM | Arrival Time 02:50PM | Duration 5h10 | Departure days Sun | Cheapest price $32 |
Operator FlixBus | Departure Time 09:58AM | Arrival Time 07:40PM | Duration 9h42 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $40 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 03:00PM | Duration 5h00 | Departure days Sun | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 04:00PM | Duration 5h30 | Departure days Sat | Cheapest price $56 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 07:10PM | Duration 8h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 03:50PM | Duration 4h50 | Departure days Sat | Cheapest price $56 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 07:10PM | Duration 7h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 11:40AM | Arrival Time 05:00PM | Duration 5h20 | Departure days Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 11:58AM | Arrival Time 09:40PM | Duration 9h42 | Departure days Mon | Cheapest price $75 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 09:10PM | Duration 8h10 | Departure days Everyday | Cheapest price $27 |
Operator FlixBus | Departure Time 01:58PM | Arrival Time 11:55PM | Duration 9h57 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 02:03PM | Arrival Time 10:55PM | Duration 8h52 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $39 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 11:10PM | Duration 8h55 | Departure days Sat, Sun | Cheapest price $68 |
Operator BlaBlaCar | Departure Time 02:20PM | Arrival Time 07:40PM | Duration 5h20 | Departure days Fri | Cheapest price $58 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 09:30PM | Duration 7h00 | Departure days Tue, Wed, Thu, Fri | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 03:10PM | Arrival Time 08:20PM | Duration 5h10 | Departure days Thu | Cheapest price $43 |
Operator FlixBus | Departure Time 03:50PM | Arrival Time 10:50PM | Duration 7h00 | Departure days Mon, Sat, Sun | Cheapest price $31 |
Operator FlixBus | Departure Time 03:58PM | Arrival Time 01:40AM | Duration 9h42 | Departure days Tue, Wed, Thu, Sun | Cheapest price $40 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 09:40PM | Duration 4h40 | Departure days Mon | Cheapest price $58 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 12:30AM | Duration 7h10 | Departure days Everyday | Cheapest price $28 |
Operator FlixBus | Departure Time 05:58PM | Arrival Time 03:30AM | Duration 9h32 | Departure days Thu, Fri, Sun | Cheapest price $65 |
Operator KLR | Departure Time 06:30PM | Arrival Time 07:50AM | Duration 13h20 | Departure days Mon, Tue | Cheapest price $24 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 07:30AM | Duration 9h30 | Departure days Thu, Fri, Sat, Sun | Cheapest price $62 |
Operator RegioJet a.s. | Departure Time 10:30PM | Arrival Time 04:48AM | Duration 6h18 | Departure days Everyday | Cheapest price $36 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 06:55AM | Duration 7h25 | Departure days Everyday | Cheapest price $31 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 06:55AM | Duration 6h56 | Departure days Everyday | Cheapest price $28 |
The table below shows live departures for Frankfurt am Main to Prague buses for today, Thursday, October 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h25 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 7h25 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 11:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h56 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h56 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
| Friday, October 30 | |||||
FlixBus · FlixBus | 12:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h50 | 10:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h30 | 10:35 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h00 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h15 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h45 | 11:00 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h50 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h30 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h15 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 2:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 10h00 | 12:45 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 4:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h10 | 1:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 6:05 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h25 | 1:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 6:05 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h55 | 4:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h55 | 5:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h35 | 5:35 PM Praha, M. Horákové (Hradčanská) | 0 transfersDirect | |
FlixTrain+ FlixBus | 9:58 AM Frankfurt South station | 9h12 | 7:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixTrain+ FlixBus | 9:58 AM Frankfurt South station | 10h02 | 8:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h55 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h30 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus · FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h10 | 7:50 PM Praha, Zličín | 1 transfer | |
FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h20 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h55 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus · FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h35 | 7:50 PM Praha, Zličín | 1 transfer | |
FlixBus | 1:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h10 | 9:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 1:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h30 | 9:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus | 1:58 PM Frankfurt South station | 9h57 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 1:58 PM Frankfurt South station | 9h37 | 11:35 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 2:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h00 | 9:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 5:20 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h10 | 12:30 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 5:20 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h25 | 12:45 AM Prague, Central Train Station | 0 transfersDirect | |
FlixTrain+ FlixBus | 5:58 PM Frankfurt South station | 9h32 | 3:30 AM Praha, ÚAN Florenc | 1 transfer | |
FlixTrain+ FlixBus | 5:58 PM Frankfurt South station | 8h52 | 2:50 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 10:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h30 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
(Amsterdam -> Prague) | 10:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h18 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.
There is only one provider for travel connections by bus from Frankfurt am Main to Prague. There are different departure possibilities in the morning, in the evening and at night. All connections include a changeover. The shortest route measures, including change time, a total travel time of 9 hours.
In regular service only FlixBus currently operates the route Frankfurt am Main - Prague.
The shortest route starts at 8.5 am and reaches Nuremberg after 3 hours 20 minutes. After a change-over time of 1.55 hours, the journey continues for 3.35 hours to the destination Praha Nakníecí. This route is the fastest with a total travel time of 9 hours.
Apart from the departure time in the morning at 8.5 further travel possibilities exist at 20.5 over Regensburg with a total travel time of 9.55 hours and at 0.35 with a change in Leipzig and a total travel time of 10.5 hours.
At which bus station does the long-distance bus depart from in Frankfurt am Main? The long-distance bus company FlixBus starts with all bus lines in Frankfurt am Main from the central bus station, ZOB for short, at Frankfurt main station.
At which bus station does the long-distance bus arrive in Prague? After the bus line, FlixBus in Prague will take you to different destinations. They are. Praha Hradčanská Praha Nakníecí, ÚAN Florence, Hlavní Nádraí. There are good transport connections from all places of arrival.
Find answers to the most common questions about traveling from Frankfurt am Main to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Prague buses use the Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Na Knížecí. Use this guide to compare Frankfurt am Main and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Frankfurt am Main, Hauptbahnhof is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Hauptbahnhof has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food outlets and cafes are inside the station.
Free Wi-Fi is available throughout the station. ATMs are aTMs are located near the main entrance.
Ticket office support is available at Frankfurt am Main, Hauptbahnhof.
Available at Frankfurt am Main, Hauptbahnhof: Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Hauptbahnhof: The station is fully accessible to wheelchair users.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
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