- Must visit
National Museum
Prague’s main museum on Wenceslas Square, with major natural history, archaeology, and history collections in a landmark neo-Renaissance building.
Cheapest price
$75
Average price
$115
Fastest journey
13 h 15 m
Average duration
13 h 28 m
Buses per day
40
Distance
646 km
The best way to find a cheap bus ticket from Milan to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Prague will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $75.
Of the 40 buses that leave Milan for Prague on Mon, May 25, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 25 the direct buses cover the 646 km distance in an average of 13 h 28 m but if you time it right, some buses will get you there in just 13 h 15 m .
On Mon, May 25 the slowest buses will take 13 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBusOmio recommends booking the flight as it is the most popular option from Milan to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a flight which can get you there in 3h 1m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.6kg. The ticket price range depends on the travel mode: a bus costs an average of $52, and a flight costs an average of $27.
Distance: 401 miles (646 km)
| Bus | Most popular Flight | Train |
|---|---|---|
$84 Average price Cheapest | $203 Average price | $140 Average price |
13h 37m Average total duration 13h 7m Onboard + 30m Additional time* | 6h 1m Average total duration Fastest 3h 1m Onboard + 3h 0m Additional time* | 14h 57m Average total duration 14h 27m Onboard + 30m Additional time* |
0.6 - 1.6kg CO2 emissions Lowest | 1.9 - 3.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Prague:
A bus is $56 (€46) less than a train for this route with tickets for a train from Milan to Prague costing on average $140 (€113).
A bus is $119 (€96) less than a flight for this route with tickets for a flight from Milan to Prague costing on average $203 (€164).
Other travel options to Prague take longer:
Bus takes on average 13h 7m.
Train takes on average 14h 27m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 02:35PM | Duration 13h20 | Departure days Mon, Thu, Fri, Sat | Cheapest price $82 |
Operator FlixBus | Departure Time 02:40AM | Arrival Time 09:30PM | Duration 18h50 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $92 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 08:20PM | Duration 16h10 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $80 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 02:50AM | Duration 19h20 | Departure days Wed | Cheapest price $113 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 09:30PM | Duration 13h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $59 |
Operator FlixBus | Departure Time 08:10AM | Arrival Time 03:15AM | Duration 19h05 | Departure days Tue | Cheapest price $115 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 03:15AM | Duration 19h00 | Departure days Wed, Thu | Cheapest price $93 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:45PM | Duration 14h00 | Departure days Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 12:05AM | Duration 14h20 | Departure days Wed, Sat | Cheapest price $82 |
Operator FlixBus | Departure Time 11:25AM | Arrival Time 05:45AM | Duration 18h20 | Departure days Mon, Thu, Fri, Sun | Cheapest price $80 |
Operator FlixBus | Departure Time 11:45AM | Arrival Time 03:15AM | Duration 15h30 | Departure days Tue | Cheapest price $80 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 07:00AM | Duration 19h00 | Departure days Mon, Thu, Fri, Sun | Cheapest price $93 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 03:15AM | Duration 13h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $85 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 08:55AM | Duration 17h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $78 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 09:25AM | Duration 17h50 | Departure days Everyday | Cheapest price $105 |
Operator RegioJet a.s. | Departure Time 03:40PM | Arrival Time 06:28AM | Duration 14h48 | Departure days Sun | Cheapest price $99 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 09:20AM | Duration 16h35 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 04:50PM | Arrival Time 09:25AM | Duration 16h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 10:45AM | Duration 17h25 | Departure days Tue | Cheapest price $98 |
Operator FlixBus | Departure Time 05:35PM | Arrival Time 09:25AM | Duration 15h50 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 06:35PM | Arrival Time 10:35AM | Duration 16h00 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 12:25PM | Duration 17h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $108 |
Operator FlixBus | Departure Time 07:25PM | Arrival Time 10:45AM | Duration 15h20 | Departure days Wed | Cheapest price $93 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 11:20AM | Duration 14h20 | Departure days Everyday | Cheapest price $69 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 11:30AM | Duration 14h20 | Departure days Everyday | Cheapest price $61 |
Operator FlixBus | Departure Time 11:10PM | Arrival Time 04:10PM | Duration 17h00 | Departure days Everyday | Cheapest price $78 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 05:45PM | Duration 18h00 | Departure days Wed | Cheapest price $91 |
The table below shows live departures for Milan to Prague buses for today, Sunday, May 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 17h30 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 13h15 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 19h00 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 23h25 | 3:00 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 17h50 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
(Milan -> Prague) | 3:40 PM Milano, Autostazione Lampugnano | 14h48 | 6:28 AM Praha, ÚAN Florenc | 0 transfersDirect | |
(Milan -> Prague) | 3:40 PM Milano, Autostazione Lampugnano | 14h45 | 6:25 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus | 4:45 PM Milano, Autostazione Lampugnano | 16h35 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h35 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 18h55 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 5:35 PM Milano, Autostazione Lampugnano | 15h50 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:35 PM Milano, Autostazione Lampugnano | 18h10 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h55 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h10 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, Autostazione Lampugnano | 18h45 | 1:20 PM Praha, Roztyly | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h00 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, Autostazione Lampugnano | 19h10 | 1:45 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h15 | 12:25 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h00 | 12:10 PM Prague, Central Train Station | 2 transfers | |
FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 14h20 | 11:20 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 14h30 | 11:30 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 9:00 PM Milano, Milan Linate Airport | 24h30 | 9:30 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Milano, Milan Linate Airport | 23h55 | 8:55 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus | 9:10 PM Milano, Autostazione Lampugnano | 14h20 | 11:30 AM Praha, Zličín | 1 transfer | |
FlixBus | 9:10 PM Milano, Autostazione Lampugnano | 13h25 | 10:35 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 11:10 PM Milano, Autostazione Lampugnano | 18h25 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| Monday, May 25 | |||||
FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 13h20 | 2:35 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 13h30 | 2:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 17h55 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 2:40 AM Milano, Autostazione Lampugnano | 18h50 | 9:30 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus | 4:10 AM Milano, Autostazione Lampugnano | 16h10 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 4:10 AM Milano, Autostazione Lampugnano | 16h25 | 8:35 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 7:40 AM Milano, Autostazione Lampugnano | 14h35 | 10:15 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 7:40 AM Milano, Autostazione Lampugnano | 13h50 | 9:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 7:40 AM Milano, Autostazione Lampugnano | 16h25 | 12:05 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 18h20 | 5:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:00 PM Milano, Milan Linate Airport | 19h10 | 7:10 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:00 PM Milano, Milan Linate Airport | 19h00 | 7:00 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milan to Prague run on average 33 times per day, taking around 13h 7m. Cheap bus tickets for this journey start at $52 (€42) but you can travel from only $27 (€22) by flight.
There are 2 buses per day. The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 401 miles (646 km) distance in 13h 25m.
Distance 401 miles (646 km) |
Average bus duration 13h 7m |
Cheapest ticket price $52 (€42) |
Buses per day 33 |
Direct buses 2 |
Fastest bus 13h 25m |
First bus 1:00 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 7 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s main museum on Wenceslas Square, with major natural history, archaeology, and history collections in a landmark neo-Renaissance building.
A major museum complex preserving Jewish heritage through historic synagogues, cemetery sites, and exhibitions in Josefov.
A refined museum of glass, ceramics, fashion, graphic design, and applied arts, popular with visitors interested in Czech design heritage.
Prague’s historic central square, surrounded by major monuments and lively throughout the day and evening.
A baroque quarter of embassies, cobbled lanes, and scenic corners below Prague Castle, ideal for wandering.
A broad boulevard-like square central to modern Czech history, shopping, and city life.
A classic Czech dish of marinated beef sirloin with a creamy root-vegetable sauce, bread dumplings, cranberry sauce, and whipped cream. It is one of Prague’s most iconic comfort foods.
Traditional roast pork served with bread dumplings and braised sauerkraut. This hearty combination is a staple of Czech home cooking and pub menus in Prague.
Czech-style goulash, usually beef, seasoned with paprika and onions and served with bread dumplings. It is thicker and less soupy than the Hungarian version and very common in Prague.
A long-established favorite for generous portions of traditional Czech cuisine, friendly service, and a relaxed neighborhood atmosphere.
Established Old Town restaurant focusing on refined Czech cuisine, including classic sauces, dumplings, and seasonal dishes in a polished setting.
A well-known Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively casual setting.
Moderate by European standards: beer, transit, and casual dining are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Small rounding in taxis is polite. Not expected for counter service, but appreciated.
Official public transport app
Praha Hlavní Nádraží, Prague -> Old Town Square, Prague
Buses in Europe are a convenient way to travel between cities, with a variety of routes available to both domestic and international destinations. Buses from Milan to Prague leave at regular intervals throughout the day, from early morning until early evening. Hellö and Flixbus are the main bus companies that travel from Milan to Prague. Travel times on buses from Milan to Prague range from 13 hours to just under 20 hours, depending on the service chosen.
Return buses from Prague to Milan | Compare all modes of traveling from Milan to Prague | Or learn more about buses to Prague
Average prices for buses from Milan to Prague when you book in advance
Booking Period |
Average Price |
|---|---|
Same Day |
€55 |
1 Day in Advance |
€55 |
1 Week in Advance |
€53 |
2 Weeks in Advance |
€50 |
1 Month in Advance |
€50 |
3 Months in Advance |
€50 |
Milan to Prague Buses: General Information
While buses are slower than both flights and trains, they can be significantly cheaper even though they take at least 13 hours to arrive in Prague.
Based on Omio's travel data, as the table above clearly illustrates, ticket prices on Milan to Prague buses decrease the further they are booked in advance:
Find answers to the most common questions about traveling from Milan to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need