- Must visit
National Museum
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.







Cheapest price
$77
Average price
$115
Fastest journey
13h 25m
Average duration
17h 8m
Buses per day
7
Distance
647 km
Omio recommends booking the flight as it is the most popular option from Milan to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a flight which can get you there in 3h 1m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.6kg. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $27.
Distance: 401 miles (646 km)
| Bus | Most popular Flight | Train |
|---|---|---|
$82 Average price Cheapest | $199 Average price | $138 Average price |
13h 37m Average total duration 13h 7m Onboard + 30m Additional time* | 6h 1m Average total duration Fastest 3h 1m Onboard + 3h 0m Additional time* | 14h 57m Average total duration 14h 27m Onboard + 30m Additional time* |
0.6 - 1.6kg CO2 emissions Lowest | 1.9 - 3.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Prague:
A bus is $55 (€46) less than a train for this route with tickets for a train from Milan to Prague costing on average $138 (€113).
A bus is $117 (€96) less than a flight for this route with tickets for a flight from Milan to Prague costing on average $199 (€164).
Other travel options to Prague take longer:
Bus takes on average 13h 7m.
Train takes on average 14h 27m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 05:30PM | Duration 16h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $117 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 08:35PM | Duration 16h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $94 |
Operator FlixBus | Departure Time 07:00AM | Arrival Time 10:25PM | Duration 15h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 03:15AM | Duration 19h00 | Departure days Tue, Thu, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:55PM | Duration 14h10 | Departure days Sun | Cheapest price $146 |
Operator FlixBus | Departure Time 11:25AM | Arrival Time 05:45AM | Duration 18h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 11:45AM | Arrival Time 03:15AM | Duration 15h30 | Departure days Tue | Cheapest price $98 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 07:10AM | Duration 19h10 | Departure days Mon, Tue, Thu, Fri | Cheapest price $73 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 08:55AM | Duration 18h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 07:10AM | Duration 16h10 | Departure days Mon, Tue, Thu, Fri | Cheapest price $95 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 03:00PM | Duration 23h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $134 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 09:20AM | Duration 16h35 | Departure days Everyday | Cheapest price $107 |
Operator FlixBus | Departure Time 04:50PM | Arrival Time 11:45AM | Duration 18h55 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 10:45AM | Duration 17h25 | Departure days Tue, Wed, Thu, Fri, Sun | Cheapest price $90 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 11:45AM | Duration 17h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $90 |
Operator FlixBus | Departure Time 06:35PM | Arrival Time 10:45AM | Duration 16h10 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 01:30PM | Duration 18h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 11:30AM | Duration 14h30 | Departure days Everyday | Cheapest price $74 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 11:30AM | Duration 14h20 | Departure days Everyday | Cheapest price $74 |
Operator FlixBus | Departure Time 11:10PM | Arrival Time 05:35PM | Duration 18h25 | Departure days Everyday | Cheapest price $91 |
The table below shows live departures for Milan to Prague buses for today, Wednesday, July 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 14h30 | 11:30 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 14h20 | 11:20 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 9:00 PM Milano, Milan Linate Airport | 27h55 | 12:55 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 9:10 PM Milano, Autostazione Lampugnano | 14h20 | 11:30 AM Praha, Zličín | 1 transfer | |
FlixBus | 9:10 PM Milano, Autostazione Lampugnano | 13h25 | 10:35 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 11:10 PM Milano, Autostazione Lampugnano | 18h25 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 11:10 PM Milano, Autostazione Lampugnano | 17h00 | 4:10 PM Praha, Černý Most | 1 transfer | |
| Thursday, July 9 | |||||
FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 16h30 | 5:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 16h15 | 5:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 17h55 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 4:10 AM Milano, Autostazione Lampugnano | 16h25 | 8:35 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:10 AM Milano, Autostazione Lampugnano | 16h10 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 7:00 AM Milano, Autostazione Lampugnano | 15h15 | 10:15 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 7:00 AM Milano, Autostazione Lampugnano | 15h25 | 10:25 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:00 AM Milano, Autostazione Lampugnano | 17h30 | 12:30 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 19h00 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 18h20 | 5:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:00 PM Milano, Milan Linate Airport | 19h10 | 7:10 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:00 PM Milano, Milan Linate Airport | 19h00 | 7:00 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 13h15 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 17h30 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 18h55 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 3:00 PM Milano, Autostazione Lampugnano | 16h00 | 7:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 3:00 PM Milano, Autostazione Lampugnano | 16h10 | 7:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 23h25 | 3:00 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 17h50 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 19h00 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 4:45 PM Milano, Autostazione Lampugnano | 16h35 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:50 PM Milano, Autostazione Lampugnano | 18h55 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 4:50 PM Milano, Autostazione Lampugnano | 16h35 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 18h55 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 4:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h35 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:20 PM Milano, Autostazione Lampugnano | 17h25 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h00 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h55 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h10 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, Autostazione Lampugnano | 19h10 | 1:45 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, Autostazione Lampugnano | 18h45 | 1:20 PM Praha, Roztyly | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milan to Prague run on average 33 times per day, taking around 13h 7m. Cheap bus tickets for this journey start at $51 (€42) but you can travel from only $27 (€22) by flight.
There are 2 buses per day. The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 401 miles (646 km) distance in 13h 25m.
Distance 401 miles (646 km) |
Average bus duration 13h 7m |
Cheapest ticket price $51 (€42) |
Buses per day 33 |
Direct buses 2 |
Fastest bus 13h 25m |
First bus 1:00 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 7 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s main museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, science, and history collections.
One of Prague’s most significant museum institutions, preserving Jewish history through synagogues, exhibitions, and the Old Jewish Cemetery.
A leading city gallery in a Gothic landmark on Old Town Square, hosting major modern and contemporary art exhibitions.
Prague’s historic heart, surrounded by major monuments and lively at all times of day; essential for first-time visitors.
A picturesque Baroque district below Prague Castle with quiet lanes, embassies, gardens, and classic city charm.
A major boulevard-like square central to modern Czech history, shopping, and the city’s urban energy.
Marinated beef sirloin with a creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the most iconic Czech Sunday and festive dishes.
Roast pork served with bread dumplings and braised sauerkraut. This is a classic Czech pub and home-style meal strongly associated with Bohemian cooking.
Czech goulash is a rich beef stew seasoned with onion and paprika, usually served with bread dumplings. It is a staple of traditional Prague taverns and beer halls.
A Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients, tasting menus, and a sophisticated modern atmosphere.
An elegant grand café offering refined Czech and Central European dishes, excellent breakfasts, and classic pastries in a beautifully restored interior.
A well-regarded Old Town restaurant focused on updated Czech cuisine, including svíčková and goulash, in a polished but approachable setting.
Moderate for Europe: beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip is expected for fast food, but small change is appreciated in cafés.
Official public transport app
Prague Main Railway Station -> Old Town Square, Prague
Buses in Europe are a convenient way to travel between cities, with a variety of routes available to both domestic and international destinations. Buses from Milan to Prague leave at regular intervals throughout the day, from early morning until early evening. Hellö and Flixbus are the main bus companies that travel from Milan to Prague. Travel times on buses from Milan to Prague range from 13 hours to just under 20 hours, depending on the service chosen.
Return buses from Prague to Milan | Compare all modes of traveling from Milan to Prague | Or learn more about buses to Prague
Average prices for buses from Milan to Prague when you book in advance
Booking Period |
Average Price |
|---|---|
Same Day |
€55 |
1 Day in Advance |
€55 |
1 Week in Advance |
€53 |
2 Weeks in Advance |
€50 |
1 Month in Advance |
€50 |
3 Months in Advance |
€50 |
Milan to Prague Buses: General Information
While buses are slower than both flights and trains, they can be significantly cheaper even though they take at least 13 hours to arrive in Prague.
Based on Omio's travel data, as the table above clearly illustrates, ticket prices on Milan to Prague buses decrease the further they are booked in advance:
Find answers to the most common questions about traveling from Milan to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Milan to Prague buses use the Milano, Autostazione Lampugnano to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Milan and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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