- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$96
Average price
$131
Fastest journey
13 h 15 m
Average duration
13 h 34 m
Buses per day
34
Distance
646 km
The best way to find a cheap bus ticket from Milan to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Prague will cost around $131 if you buy it on the day, but the cheapest tickets can be found for only $96.
Of the 34 buses that leave Milan for Prague on Mon, Aug 24, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Aug 24 the direct buses cover the 646 km distance in an average of 13 h 34 m but if you time it right, some buses will get you there in just 13 h 15 m .
On Mon, Aug 24 the slowest buses will take 14 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus · FlixBus
FlixBus
FlixBus
FlixBus · FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
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FlixBus · FlixBus
FlixBusOmio recommends booking the flight as it is the most popular option from Milan to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $54. For those with little time consider booking a flight which can get you there in 2h 55m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.6kg. The ticket price range depends on the travel mode: a bus costs an average of $54, and a train costs an average of $104.
Distance: 401 miles (646 km)
| Bus | Most popular Flight | Train |
|---|---|---|
$89 Average price Cheapest | $126 Average price | $312 Average price |
13h 38m Average total duration 13h 8m Onboard + 30m Additional time* | 5h 55m Average total duration Fastest 2h 55m Onboard + 3h 0m Additional time* | 14h 57m Average total duration 14h 27m Onboard + 30m Additional time* |
0.6 - 1.6kg CO2 emissions Lowest | 1.9 - 3.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Prague:
A bus is $57 (€46) less than a train for this route with tickets for a train from Milan to Prague costing on average $141 (€113).
A bus is $120 (€96) less than a flight for this route with tickets for a flight from Milan to Prague costing on average $204 (€164).
Other travel options to Prague take longer:
Bus takes on average 13h 7m.
Train takes on average 14h 27m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 02:45PM | Duration 13h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $108 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 08:35PM | Duration 16h25 | Departure days Everyday | Cheapest price $104 |
Operator FlixBus | Departure Time 07:00AM | Arrival Time 10:25PM | Duration 15h25 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 02:50AM | Duration 19h20 | Departure days Wed | Cheapest price $117 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 03:15AM | Duration 19h00 | Departure days Tue, Wed, Thu, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:55PM | Duration 14h10 | Departure days Sun | Cheapest price $141 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 05:45AM | Duration 19h15 | Departure days Wed | Cheapest price $113 |
Operator FlixBus | Departure Time 11:25AM | Arrival Time 05:45AM | Duration 18h20 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $104 |
Operator FlixBus | Departure Time 11:45AM | Arrival Time 03:15AM | Duration 15h30 | Departure days Tue, Wed | Cheapest price $115 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 07:10AM | Duration 19h10 | Departure days Everyday | Cheapest price $83 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 03:15AM | Duration 13h15 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $114 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 08:55AM | Duration 17h55 | Departure days Everyday | Cheapest price $103 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 03:00PM | Duration 23h25 | Departure days Everyday | Cheapest price $85 |
Operator RegioJet a.s. | Departure Time 03:40PM | Arrival Time 06:28AM | Duration 14h48 | Departure days Sun | Cheapest price $143 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 09:20AM | Duration 16h35 | Departure days Everyday | Cheapest price $105 |
Operator FlixBus | Departure Time 04:50PM | Arrival Time 09:25AM | Duration 16h35 | Departure days Everyday | Cheapest price $101 |
Operator FlixBus | Departure Time 05:20PM | Arrival Time 10:45AM | Duration 17h25 | Departure days Tue, Wed, Thu, Fri, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 12:45PM | Duration 18h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $121 |
Operator FlixBus | Departure Time 06:35PM | Arrival Time 11:30AM | Duration 16h55 | Departure days Everyday | Cheapest price $98 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 01:20PM | Duration 18h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $124 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 11:30AM | Duration 14h30 | Departure days Everyday | Cheapest price $81 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 11:30AM | Duration 14h20 | Departure days Everyday | Cheapest price $73 |
Operator FlixBus | Departure Time 11:10PM | Arrival Time 04:10PM | Duration 17h00 | Departure days Everyday | Cheapest price $100 |
The table below shows live departures for Milan to Prague buses for today, Sunday, August 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:00 AM Milano, Autostazione Lampugnano | 15h15 | 10:15 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 7:00 AM Milano, Autostazione Lampugnano | 15h25 | 10:25 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:00 AM Milano, Autostazione Lampugnano | 17h30 | 12:30 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 19h00 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 8:45 AM Milano, Autostazione Lampugnano | 14h10 | 10:55 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 8:45 AM Milano, Autostazione Lampugnano | 14h00 | 10:45 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:00 PM Milano, Milan Linate Airport | 19h10 | 7:10 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:00 PM Milano, Milan Linate Airport | 19h00 | 7:00 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 17h30 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 13h15 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:00 PM Milano, Autostazione Lampugnano | 17h55 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 3:00 PM Milano, Autostazione Lampugnano | 16h00 | 7:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 3:00 PM Milano, Autostazione Lampugnano | 16h10 | 7:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 19h00 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 23h25 | 3:00 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 3:35 PM Milano, Milan Linate Airport | 17h50 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
(Milan -> Prague) | 3:40 PM Milano, Autostazione Lampugnano | 14h48 | 6:28 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 4:45 PM Milano, Autostazione Lampugnano | 16h35 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 18h55 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 4:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h35 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:50 PM Milano, Autostazione Lampugnano | 16h35 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:20 PM Milano, Autostazione Lampugnano | 17h25 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:00 PM Milano, Autostazione Lampugnano | 17h45 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 6:35 PM Milano, Autostazione Lampugnano | 18h45 | 1:20 PM Praha, Roztyly | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, Autostazione Lampugnano | 19h10 | 1:45 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h55 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h00 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h10 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h15 | 12:25 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h00 | 12:10 PM Prague, Central Train Station | 2 transfers | |
FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 14h20 | 11:20 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 14h30 | 11:30 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 9:10 PM Milano, Autostazione Lampugnano | 14h20 | 11:30 AM Praha, Zličín | 1 transfer | |
FlixBus | 9:10 PM Milano, Autostazione Lampugnano | 13h25 | 10:35 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus | 11:10 PM Milano, Autostazione Lampugnano | 17h00 | 4:10 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:10 PM Milano, Autostazione Lampugnano | 18h25 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
| Monday, August 24 | |||||
FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 13h30 | 2:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 17h55 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 1:15 AM Milano, Autostazione Lampugnano | 13h20 | 2:35 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:10 AM Milano, Autostazione Lampugnano | 16h25 | 8:35 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:10 AM Milano, Autostazione Lampugnano | 16h10 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milan to Prague run on average 33 times per day, taking around 13h 7m. Cheap bus tickets for this journey start at $52 (€42) but you can travel from only $27 (€22) by flight.
There are 2 buses per day. The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 401 miles (646 km) distance in 13h 25m.
Distance 401 miles (646 km) |
Average bus duration 13h 7m |
Cheapest ticket price $52 (€42) |
Buses per day 33 |
Direct buses 2 |
Fastest bus 13h 25m |
First bus 1:00 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Best time to book 7 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Buses in Europe are a convenient way to travel between cities, with a variety of routes available to both domestic and international destinations. Buses from Milan to Prague leave at regular intervals throughout the day, from early morning until early evening. Hellö and Flixbus are the main bus companies that travel from Milan to Prague. Travel times on buses from Milan to Prague range from 13 hours to just under 20 hours, depending on the service chosen.
Return buses from Prague to Milan | Compare all modes of traveling from Milan to Prague | Or learn more about buses to Prague
Average prices for buses from Milan to Prague when you book in advance
Booking Period |
Average Price |
|---|---|
Same Day |
€55 |
1 Day in Advance |
€55 |
1 Week in Advance |
€53 |
2 Weeks in Advance |
€50 |
1 Month in Advance |
€50 |
3 Months in Advance |
€50 |
Milan to Prague Buses: General Information
While buses are slower than both flights and trains, they can be significantly cheaper even though they take at least 13 hours to arrive in Prague.
Based on Omio's travel data, as the table above clearly illustrates, ticket prices on Milan to Prague buses decrease the further they are booked in advance:
Find answers to the most common questions about traveling from Milan to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Milan to Prague buses use the Milano, Autostazione Lampugnano to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Milan and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need