The cheapest and fastest buses from Karlsruhe to Florence
Cheapest price
$52
Average price
$75
Fastest journey
13 h 45 m
Average duration
15 h 34 m
Buses per day
3
Distance
622 km
The best way to find a cheap bus ticket from Karlsruhe to Florence is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Florence will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $52.
Of the 3 buses that leave Karlsruhe for Florence on Sun, Mar 22, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct buses cover the 622 km distance in an average of 15 h 34 m but if you time it right, some buses will get you there in just 13 h 45 m .
On Sun, Mar 22 the slowest buses will take 18 h 42 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus and train for Karlsruhe to Florence
Omio recommends booking the train as it is the most popular option from Karlsruhe to Florence among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a train which can get you there in 7h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $43, and a train costs an average of $196.
Distance: 386 miles (622 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$79 Average price Cheapest | $317 Average price |
13h 41m Average total duration 13h 11m Onboard + 30m Additional time* | 8h 24m Average total duration Fastest 7h 54m Onboard + 30m Additional time* |
0.6 - 1.6kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Karlsruhe to Florence Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 05:10PM | Duration 17h05 | Departure days Fri, Sat | Cheapest price $97 |
Operator FlixBus | Departure Time 03:20AM | Arrival Time 09:00PM | Duration 17h40 | Departure days Thu, Fri, Sat | Cheapest price $83 |
Operator FlixBus | Departure Time 03:55AM | Arrival Time 07:35PM | Duration 15h40 | Departure days Fri | Cheapest price $108 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 07:35PM | Duration 14h40 | Departure days Sat | Cheapest price $86 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 11:00PM | Duration 17h45 | Departure days Fri, Sat | Cheapest price $88 |
Operator Marino Autolinee | Departure Time 09:30AM | Arrival Time 01:15AM | Duration 15h45 | Departure days Thu, Sat | Cheapest price $100 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 11:00PM | Duration 13h30 | Departure days Fri, Sat | Cheapest price $112 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 02:40AM | Duration 16h55 | Departure days Thu | Cheapest price $79 |
Operator FlixBus | Departure Time 10:15AM | Arrival Time 03:45AM | Duration 17h30 | Departure days Thu | Cheapest price $87 |
Operator BlaBlaCar Bus | Departure Time 11:15AM | Arrival Time 10:45AM | Duration 23h30 | Departure days Fri | Cheapest price $100 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 05:40AM | Duration 18h25 | Departure days Thu | Cheapest price $131 |
Operator FlixBus | Departure Time 11:50AM | Arrival Time 02:40AM | Duration 14h50 | Departure days Fri, Sat | Cheapest price $113 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 03:45AM | Duration 15h15 | Departure days Fri, Sat | Cheapest price $86 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 06:00AM | Duration 13h30 | Departure days Thu, Fri, Sat | Cheapest price $86 |
Operator FlixBus | Departure Time 07:29PM | Arrival Time 11:15AM | Duration 15h46 | Departure days Fri | Cheapest price $165 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 10:25AM | Duration 14h15 | Departure days Thu, Fri, Sat | Cheapest price $81 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 05:10PM | Duration 17h50 | Departure days Thu, Fri, Sat | Cheapest price $83 |
Live departures
Karlsruhe to Florence bus times
The table below shows live departures for Karlsruhe to Florence buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:55 AM Karlsruhe Hbf | 14h40 | 6:35 PM Scandicci, Villa Costanza (Florence) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:15 AM Karlsruhe Hbf | 17h45 | 10:00 PM Firenze, Piazzale Montelungo | 2 transfers | |
FlixBus · FlixBus | 8:30 AM Karlsruhe Hbf | 13h30 | 10:00 PM Scandicci, Villa Costanza (Florence) | 1 transfer | |
FlixBus · FlixBus | 8:30 AM Karlsruhe Hbf | 15h30 | 12:00 AM Firenze, Piazzale Montelungo | 1 transfer | |
254 · 055 | 8:30 AM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 15h45 | 12:15 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
FlixBus · FlixBus | 10:50 AM Karlsruhe Hbf | 14h50 | 1:40 AM Firenze, Piazzale Montelungo | 1 transfer | |
FlixBus · FlixBus | 10:50 AM Karlsruhe Hbf | 14h25 | 1:15 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
FlixBus · FlixBus | 11:30 AM Karlsruhe Hbf | 15h15 | 2:45 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
FlixBus · FlixBus | 3:30 PM Karlsruhe Hbf | 13h30 | 5:00 AM Scandicci, Villa Costanza (Florence) | 1 transfer | |
FlixBus | 7:10 PM Karlsruhe Hbf | 14h15 | 9:25 AM Scandicci, Villa Costanza (Florence) | 0 transfersDirect | |
FlixBus · FlixBus | 10:20 PM Karlsruhe Hbf | 17h50 | 4:10 PM Scandicci, Villa Costanza (Florence) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Florence by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
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Mar 28
Why should you book Karlsruhe to Florence buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlsruhe to Florence.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlsruhe to Florence.
Journey information
Overview: Bus from Karlsruhe to Florence
Buses from Karlsruhe to Florence run on average 12 times per day, taking around 13h 11m. Cheap bus tickets for this journey start at $43 (€35) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 386 miles (622 km) distance in 13h 45m.
Distance 386 miles (622 km) |
Average bus duration 13h 11m |
Cheapest ticket price $43 (€35) |
Buses per day 12 |
Direct buses 1 |
Fastest bus 13h 45m |
First bus 00:05 |
Last bus 23:55 |
Cheapest month Feb |
Cheapest day Tue |
High season Apr - Jun |
Low season Jan - Mar |
Best day to book ahead 28 days |
Bus providers: FlixBus from Karlsruhe to FlorenceYou can travel by bus between Karlsruhe to Florence with FlixBus for as low as $43 (€35). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Karlsruhe to Florence
Find answers to the most common questions about traveling from Karlsruhe to Florence by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Florence Cathedral, an iconic Gothic structure known for its stunning dome designed by Brunelleschi
- Uffizi Gallery, a renowned art museum housing masterpieces by artists like Botticelli and Michelangelo
- Ponte Vecchio, a historic bridge famous for its shops and picturesque views over the Arno River
- Palazzo Vecchio, a medieval fortress-palace that serves as Florence's town hall and a museum
- Boboli Gardens, a vast and elegant park behind Pitti Palace featuring sculptures and fountains.
- Climb to Piazzale Michelangelo, a popular spot offering panoramic views of Florence's skyline
- Visit the Accademia Gallery to see Michelangelo's David
- Take a cooking class to learn how to make traditional Tuscan dishes
- Enjoy a wine tasting tour in the Chianti region
- Explore the vibrant San Lorenzo Market for local goods and delicacies.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Karlsruhe to Florence
- 06:00-22:00
- Free Wi-Fi
- Elevators, ramps
- Available in the station.
- Bus: 37, 72 Tram: T1
- 06:00-21:00
- Free Wi-Fi
- Available near the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 12, 13, 17 Train: Firenze Santa Maria Novella
Most popular bus connections from Karlsruhe
More options for your journey from Karlsruhe to Florence
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