The cheapest and fastest buses from Harrisburg, PA to San Diego, CA
Cheapest price
$783
Average price
$783
Fastest journey
2 d 14 h 35 m
Average duration
2 d 14 h 35 m
Buses per day
1
Distance
3664 km
The best way to find a cheap bus ticket from Harrisburg, PA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to San Diego, CA will cost around $783 if you buy it on the day, but the cheapest tickets can be found for only $783.
It's difficult to get from Harrisburg, PA to San Diego, CA without transferring at least 2 times.


Travel Information
Compare train, bus, and flight for Harrisburg, PA to San Diego, CA
Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $179. For those with little time consider booking a flight which can get you there in 10h 48m. The ticket price range depends on the travel mode: a bus costs an average of $179, and a flight costs an average of $233.
Distance: 2276 miles (3664 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$350 Average price Cheapest | $496 Average price | $598 Average price |
65h 46m Average total duration 65h 16m Onboard + 30m Additional time* | 61h 47m Average total duration 61h 17m Onboard + 30m Additional time* | 13h 48m Average total duration Fastest 10h 48m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Harrisburg, PA to San Diego, CA bus times
The table below shows live departures for Harrisburg, PA to San Diego, CA buses for tomorrow, Monday, March 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:50 PM Harrisburg, PA | 62h35 | 5:25 AM San Diego, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 17
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Mar 23
Why should you book Harrisburg, PA to San Diego, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Harrisburg, PA to San Diego, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Harrisburg, PA to San Diego, CA.
Journey information
Overview: Bus from Harrisburg, PA to San Diego, CA
Buses from Harrisburg, PA to San Diego, CA run on average 11 times per day, taking around 65h 16m. Cheap bus tickets for this journey start at $179 (€146) if you book in advance.
The earliest bus runs at 09:00, the last at 19:35. The fastest bus covers the 2276 miles (3664 km) distance in 66h 15m.
Distance 2276 miles (3664 km) |
Average bus duration 65h 16m |
Cheapest ticket price $179 (€146) |
Buses per day 11 |
Fastest bus 66h 15m |
First bus 09:00 |
Last bus 19:35 |
Cheapest month May |
Cheapest day Wed |
High season Jan - Mar |
Low season Oct - Dec |
Bus providers: Greyhound from Harrisburg, PA to San Diego, CAYou can travel by bus between Harrisburg, PA to San Diego, CA with Greyhound for as low as $179 (€146). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Harrisburg, PA to San Diego, CA
Find answers to the most common questions about traveling from Harrisburg, PA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Harrisburg, PA to San Diego, CA
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to San Diego, CA
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