4.9
4.6The cheapest and fastest buses from Harrisburg, PA to St. Louis, MO
Cheapest price
$226
Average price
$226
Fastest journey
17 h 5 m
Average duration
18 h 20 m
Buses per day
2
Distance
1157 km
The best way to find a cheap bus ticket from Harrisburg, PA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to St. Louis, MO will cost around $226 if you buy it on the day, but the cheapest tickets can be found for only $226.
Of the 2 buses that leave Harrisburg, PA for St. Louis, MO on Tue, Apr 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Apr 21 the direct buses cover the 1157 km distance in an average of 18 h 20 m but if you time it right, some buses will get you there in just 17 h 5 m .
On Tue, Apr 21 the slowest buses will take 19 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2:50 PM17h05Harrisburg, PA7:55 AMSt. Louis, MO$2261One-way0 transfers- 7:45 PM19h35Harrisburg, PA3:20 PMSt. Louis, MO$2261One-way0 transfers
- 2:50 PM17h05Harrisburg, PA7:55 AMSt. Louis, MO$2261One-way0 transfers
- 7:45 PM19h35Harrisburg, PA3:20 PMSt. Louis, MO$2261One-way0 transfers
Travel Information
Compare train, bus, and flight for Harrisburg, PA to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $147. For those with little time consider booking a bus which can get you there in 18h 10m. The ticket price range depends on the travel mode: a bus costs an average of $147, and a train costs an average of $411.
Distance: 718 miles (1157 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$147 Average price Cheapest | $411 Average price |
18h 40m Average total duration Fastest 18h 10m Onboard + 30m Additional time* | 24h 45m Average total duration 24h 15m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Harrisburg, PA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:30AM | Arrival Time 11:45PM | Duration 22h15 | Departure days Mon | Cheapest price $212 |
Operator Greyhound | Departure Time 02:50PM | Arrival Time 07:55AM | Duration 18h05 | Departure days Mon | Cheapest price $138 |
Operator Greyhound | Departure Time 07:50PM | Arrival Time 03:10PM | Duration 20h20 | Departure days Mon | Cheapest price $143 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 03:10PM | Duration 20h05 | Departure days Mon | Cheapest price $204 |
Operator Greyhound | Departure Time 09:10PM | Arrival Time 11:45PM | Duration 27h35 | Departure days Mon | Cheapest price $250 |
Live departures
Harrisburg, PA to St. Louis, MO bus times
The table below shows live departures for Harrisburg, PA to St. Louis, MO buses for today, Monday, April 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 7:50 PM Harrisburg, Market St (Bus Station), PA | 20h20 | 3:10 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| Tuesday, April 21 | |||||
| undefined · undefined | 8:05 PM Harrisburg, Market St (Bus Station), PA | 20h05 | 3:10 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| undefined · undefined | 9:10 PM Harrisburg, Market St (Bus Station), PA | 27h35 | 11:45 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| 2:50 PM Harrisburg, PA | 17h05 | 7:55 AM St. Louis, MO | 0 transfersDirect | |
| 7:45 PM Harrisburg, PA | 19h35 | 3:20 PM St. Louis, MO | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 21
Apr 22
Apr 23
Apr 24
Apr 25
Apr 26
Apr 27
Why should you book Harrisburg, PA to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Harrisburg, PA to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Harrisburg, PA to St. Louis, MO.
Journey information
Overview: Bus from Harrisburg, PA to St. Louis, MO
USAUSA
Buses from Harrisburg, PA to St. Louis, MO run on average 5 times per day, taking around 18h 10m. Cheap bus tickets for this journey start at $147 (€117) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 718 miles (1157 km) distance in 18h 5m.
Distance 718 miles (1157 km) |
Average bus duration 18h 10m |
Cheapest ticket price $147 (€117) |
Buses per day 5 |
Direct buses 1 |
Fastest bus 18h 5m |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jan - Mar |
Best time to book 2 days |
Bus providers: Greyhound from Harrisburg, PA to St. Louis, MOYou can travel by bus between Harrisburg, PA to St. Louis, MO with Greyhound for as low as $147 (€117). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Harrisburg, PA to St. Louis, MO
Find answers to the most common questions about traveling from Harrisburg, PA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Harrisburg, PA to St. Louis, MO
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Harrisburg, PA
Most popular bus connections to St. Louis, MO
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