- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Cheapest price on Sep 06
$107
Average ticket price on Sep 06
$122
Fastest journey on Sep 06
14 h 55 m
Average journey duration on Sep 06
17 h 14 m
Buses on Sep 06
5
Distance
919 km
The best way to find a cheap bus ticket from Harrisburg, PA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Chicago, IL will cost around $122 if you buy it on the day, but the cheapest tickets can be found for only $107.
On Sun, Sep 06, we found 5 buses from Harrisburg, PA to Chicago, IL, including 2 direct services.
On Sun, Sep 06 the direct buses cover the 919 km distance in an average of 17 h 14 m but if you time it right, some buses will get you there in just 14 h 55 m .
On Sun, Sep 06 the slowest buses will take 18 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus
FlixBus
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FlixBus
FlixBus
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· · Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Chicago, IL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $139 For those with little time, consider booking a flight, which has an average total journey time of 5h 55m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.3 - 0.8kg. Average ticket prices depend on the travel mode: a bus costs an average of $139, while a flight costs an average of $642.
Distance: 571 miles (919 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$139 Average price Cheapest | $306 Average price | $642 Average price | $241 Average price (fuel + tolls) |
16h 46m Average total duration 16h 16m Onboard + 30m Additional time* | 17h 52m Average total duration 17h 22m Onboard + 30m Additional time* | 5h 55m Average total duration Fastest 3h 55m Onboard + 2h 0m Additional time* | 9h 51m Average total duration (door-to-door) |
0.9 - 2.3kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Harrisburg, PA to Chicago, IL:
A bus is $167 (€135) less than a train for this route with tickets for a train from Harrisburg, PA to Chicago, IL costing on average $306 (€247).
A bus is $503 (€407) less than a flight for this route with tickets for a flight from Harrisburg, PA to Chicago, IL costing on average $642 (€519).
Other travel options to Chicago, IL take longer:
Bus takes on average 16h 16m.
Train takes on average 17h 22m.
Tickets start at around $139 (€112) compared to roughly $241 (€195) in fuel and tolls — a saving of about $102 (€83). The journey takes 16h 16m versus 9h 51m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:15AM | Arrival Time 06:55PM | Duration 17h40 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 02:30AM | Arrival Time 06:55PM | Duration 17h25 | Departure days Thu, Fri | Cheapest price $90 |
Operator Greyhound | Departure Time 02:35PM | Arrival Time 08:00AM | Duration 18h25 | Departure days Mon, Tue, Sat, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 02:40PM | Arrival Time 06:10AM | Duration 16h30 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 06:10AM | Duration 16h20 | Departure days Wed, Thu, Fri | Cheapest price $90 |
Operator Greyhound | Departure Time 02:50PM | Arrival Time 08:00AM | Duration 18h10 | Departure days Wed, Thu, Fri | Cheapest price $97 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 01:45PM | Duration 18h40 | Departure days Everyday | Cheapest price $87 |
The table below shows live departures for Harrisburg, PA to Chicago, IL buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 2:15 AM Harrisburg, Market St (Bus Station), PA | 17h40 | 6:55 PM Chicago, Greyhound Bus Station | 0 transfersDirect | |
· | 2:35 PM Harrisburg, Market St (Bus Station), PA | 18h25 | 8:00 AM Chicago, Union Station (Amtrak), IL | 1 transfer | |
FlixBus | 2:40 PM Harrisburg, Market St (Bus Station), PA | 16h30 | 6:10 AM Chicago, Greyhound Bus Station | 0 transfersDirect | |
· · | 8:05 PM Harrisburg, Market St (Bus Station), PA | 18h40 | 1:45 PM Chicago, Union Station (Amtrak), IL | 2 transfers | |
· | 8:05 PM Harrisburg, Market St (Bus Station), PA | 14h55 | 10:00 AM Chicago, Greyhound Bus Station | 1 transfer |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Harrisburg, PA to Chicago, IL run on average 5 times per day, taking around 16h 16m. Cheap bus tickets for this journey start at $74 (€60) if you book in advance.
There are 2 buses per day. The earliest bus runs at 02:30, the last at 23:35. The fastest bus covers the 571 miles (919 km) distance in 14h 5m.
Distance 571 miles (919 km) |
Average bus duration 16h 16m |
Cheapest ticket price $74 (€60) |
Buses per day 5 |
Direct buses 2 |
Fastest bus 14h 5m |
First bus 2:30 AM |
Last bus 11:35 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 14 days |
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
Find answers to the most common questions about traveling from Harrisburg, PA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most Harrisburg, PA to Chicago, IL buses use the Harrisburg, Market St (Bus Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Harrisburg, PA and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Harrisburg, Chestnut Street / South 4th Street is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Chestnut Street / South 4th Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Harrisburg, Chestnut Street / South 4th Street. ATMs are available at Harrisburg, Chestnut Street / South 4th Street.
Ticket office support is available at Harrisburg, Chestnut Street / South 4th Street.
Available at Harrisburg, Chestnut Street / South 4th Street: Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Chestnut Street / South 4th Street: Accessible by wheelchair via main entrance.
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack shop and vending machines available
Free Wi-Fi in waiting area. ATMs are located near entrance.
Ticket office support is available at Chicago, Greyhound Bus Station.
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple dining options are available inside the station.
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Ticket office support is available at Chicago, Union Station (Amtrak).
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
Chicago, 95th Red Line Station is 14 km from Chicago city centre. Public transport options include:
Chicago, 95th Red Line Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Chicago, 95th Red Line Station. ATMs are available at Chicago, 95th Red Line Station.
Ticket office support is available at Chicago, 95th Red Line Station.
Available at Chicago, 95th Red Line Station: Parking, Taxis, WC.
Accessibility facilities are available at Chicago, 95th Red Line Station: Wheelchair accessible entrances available.
Here are some other resources that might have the information you need