Harrisburg, PA to San Francisco, CA bus with Greyhound

Sat, Jun 06
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The cheapest and fastest buses from Harrisburg, PA to San Francisco, CA

Showing times and prices for Jun 06

Cheapest price

$234

Average price

$236

Fastest journey

2 d 19 h 20 m

Average duration

2 d 21 h 10 m

Buses per day

3

Distance

3900 km

Cheap tickets

The best way to find a cheap bus ticket from Harrisburg, PA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Harrisburg, PA to San Francisco, CA will cost around $236 if you buy it on the day, but the cheapest tickets can be found for only $234.

Fast buses

It's difficult to get from Harrisburg, PA to San Francisco, CA without transferring at least 3 times.

  • Greyhound · · ·
    8:05 PM72h45
    Harrisburg, Market St (Bus Station), PA
    5:50 PMSan Francisco, Townsend Street / 5th Street, CA
    $2341One-way
    5 transfers
  • Greyhound · · ·
    8:05 PM67h20
    Harrisburg, Market St (Bus Station), PA
    12:25 PMSan Francisco, Transit Center Bay 29
    $2371One-way
    4 transfers
  • Greyhound · · ·
    2:50 PM67h25
    Harrisburg, Market St (Bus Station), PA
    7:15 AMSan Francisco, Transit Center Bay 29
    $2381One-way
    3 transfers

Travel Information

Compare bus, train, and flight for Harrisburg, PA to San Francisco, CA

Omio recommends booking the train as it is the most popular option from Harrisburg, PA to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $244. For those with little time consider booking a flight which can get you there in 9h 45m. The ticket price range depends on the travel mode: a bus costs an average of $244, and a train costs an average of $2874.

Distance: 2423 miles (3900 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$287

Average price

Cheapest

$2916

Average price

$502

Average price

$567

Average price

(fuel + tolls)

67h 50m

Average total duration

67h 20m

Onboard

+

30m

Additional time*

68h 35m

Average total duration

68h 5m

Onboard

+

30m

Additional time*

12h 45m

Average total duration

Fastest

9h 45m

Onboard

+

3h 0m

Additional time*

40h 47m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Harrisburg, PA to San Francisco, CA is a bus with an average price of $287 (€232).

This is compared to other travel options from Harrisburg, PA to San Francisco, CA:

A bus is $215 (€174) less than a flight for this route with tickets for a flight from Harrisburg, PA to San Francisco, CA costing on average $502 (€406).

A bus is $2629 (€2126) less than a train for this route with tickets for a train from Harrisburg, PA to San Francisco, CA costing on average $2916 (€2357).

The fastest way to travel from Harrisburg, PA to San Francisco, CA is by flight with an average journey time of 9h 45m.

Other travel options to San Francisco, CA take longer:

Bus takes on average 67h 20m.

Train takes on average 68h 5m.

It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and San Francisco, CA including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to San Francisco, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Harrisburg, PA to San Francisco, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:05AM
Arrival Time
07:25PM
Duration
67h20
Departure days
Wed, Fri
Cheapest price
$245
Operator
Greyhound
Departure Time
01:05AM
Arrival Time
08:25PM
Duration
67h20
Departure days
Sat
Cheapest price
$244
Operator
Greyhound USA
Departure Time
02:50PM
Arrival Time
07:15AM
Duration
64h25
Departure days
Wed, Sat
Cheapest price
$238
Operator
Greyhound USA
Departure Time
07:45PM
Arrival Time
12:25PM
Duration
64h40
Departure days
Wed
Cheapest price
$784
Operator
Greyhound
Departure Time
08:05PM
Arrival Time
05:50PM
Duration
72h45
Departure days
Sat
Cheapest price
$234

Compare prices and tickets Harrisburg, PA to San Francisco, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Jun 06
Sun
Jun 07
Mon
Jun 08
Tue
Jun 09
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12

Why should you book Harrisburg, PA to San Francisco, CA buses with Omio?

Greyhound operates all buses services from Harrisburg, PA to San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Harrisburg, PA to San Francisco, CA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Harrisburg, PA to San Francisco, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Harrisburg, PA to San Francisco, CA.

Journey information

Overview: Bus from Harrisburg, PA to San Francisco, CA

USAUSA
USAUSA
Icon of bus

Buses from Harrisburg, PA to San Francisco, CA run on average 4 times per day, taking around 67h 20m. Cheap bus tickets for this journey start at $244 (€197) if you book in advance.

The earliest bus runs at 07:00, the last at 23:25. The fastest bus covers the 2423 miles (3900 km) distance in 67h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
2423 miles (3900 km)
Average bus duration
67h 20m
Cheapest ticket price
$244 (€197)
Buses per day
4
Fastest bus
67h 20m
First bus
7:00 AM
Last bus
11:25 PM
Cheapest Month
Dec
Cheapest Day
Fri
High Season
Jan - Mar
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Harrisburg, PA to San Francisco, CAYou can travel by bus between Harrisburg, PA to San Francisco, CA with Greyhound for as low as $244 (€197). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
67h 20m
Cheapest Price
$244 (€197)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to San Francisco

Things to do in San Francisco

Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.

  • Must visit

San Francisco Museum of Modern Art

Major modern and contemporary art museum with an outstanding collection, rotating exhibitions, and a central SoMa location.

  • Must visit

Exploratorium

Hands-on science and perception museum on the Embarcadero, especially popular for interactive exhibits and bay views.

  • Recommended

de Young Museum

Fine arts museum in Golden Gate Park known for American art, textiles, global collections, and its observation tower.

United States Dollar

One of the priciest U.S. cities. Hotels, dining, parking, and taxes are high, though casual food options exist.

Average meal costs

Budget
USD 12-20 for fast food, food trucks, or a simple cafe meal.
Mid-range
USD 25-45 per person at a casual sit-down restaurant.
Fine dining
USD 90+ per person before drinks, tax, and tip.
Coffee
USD 4-7 for drip coffee or a basic latte.

Tipping culture

Restaurants: 18-20% standard, 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotels: USD 2-5 for housekeeping, USD 1-2 per bag for porters.

FAQs: Bus from Harrisburg, PA to San Francisco, CA

Find answers to the most common questions about traveling from Harrisburg, PA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Harrisburg, PA to San Francisco, CA can start from as little as $244 (€197) when you book in advance. The average bus ticket price for Harrisburg, PA to San Francisco, CA is $287 (€232) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to San Francisco, CA is 67h 20m to travel the 2423 miles (3900 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to San Francisco, CA leaves at 7:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to San Francisco, CA leaves at 11:25 PM.
There are 4 buses a day from Harrisburg, PA to San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Harrisburg, PA to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus companies who offer a service between Harrisburg, PA and San Francisco, CA and compare the amenities they offer before buying a bus ticket.
A trip to San Francisco, CA from Harrisburg, PA is worth doing but not as a day trip with a journey time of 67h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Harrisburg, PA to San Francisco, CA is December.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and San Francisco, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to San Francisco, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Harrisburg, PA to San Francisco, CA for bus company Greyhound.
Some of the most interesting sights to explore in San Francisco, CA are:
  • Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
  • Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
  • Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
  • Golden Gate Park, a large urban park with gardens, museums, and recreational activities
  • Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
  • Ride a cable car through the steep streets of San Francisco for a classic city experience
  • Explore the vibrant murals and street art in the Mission District
  • Visit the Exploratorium, an interactive science museum perfect for all ages
  • Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
  • Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
Whether you can cancel your bus ticket from Harrisburg, PA to San Francisco, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Harrisburg, PA to San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to San Francisco, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to San Francisco, CA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to San Francisco, CA.
You can reserve your seat on the bus from Harrisburg, PA to San Francisco, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Harrisburg, PA to San Francisco, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Harrisburg, PA to San Francisco, CA with the following bus company: Greyhound.
Since neither Harrisburg, PA nor San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to San Francisco, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Harrisburg, PA to San Francisco, CA

Harrisburg
San Francisco
The major bus station for departures in Harrisburg is Harrisburg, Market St (Bus Station). Find all the information you need to know about services, amenities and connections at Harrisburg, Market St (Bus Station) for your trip from Harrisburg to San Francisco.
Harrisburg, Market St (Bus Station)
information
Harrisburg, Chestnut Street / South 4th Street
information

More options for your journey from Harrisburg, PA to San Francisco, CA

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Most popular buses to and from San Francisco, CA and Harrisburg, PA

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