- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Harrisburg, PA to San Francisco, CA
Showing times and prices for Jul 22
Cheapest price
$771
Average price
$801
Fastest journey
2 d 16 h 25 m
Average duration
2 d 16 h 33 m
Buses per day
2
Distance
3900 km
Cheap tickets
The best way to find a cheap bus ticket from Harrisburg, PA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to San Francisco, CA will cost around $801 if you buy it on the day, but the cheapest tickets can be found for only $771.
Fast buses
It's difficult to get from Harrisburg, PA to San Francisco, CA without transferring at least 2 times.
7:45 PM64h40Harrisburg, PA12:25 PMSan Francisco, CA$7711One-way3 transfers- 2:50 PM64h25Harrisburg, PA7:15 AMSan Francisco, CA$8321One-way2 transfers
- 2:50 PM64h25Harrisburg, PA7:15 AMSan Francisco, CA$8321One-way2 transfers
- 7:45 PM64h40Harrisburg, PA12:25 PMSan Francisco, CA$7711One-way3 transfers
Travel Information
Compare bus, train, and flight for Harrisburg, PA to San Francisco, CA
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $239. For those with little time consider booking a flight which can get you there in 9h 45m. The ticket price range depends on the travel mode: a bus costs an average of $239, and a train costs an average of $2826.
Distance: 2423 miles (3900 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$282 Average price Cheapest | $2867 Average price | $493 Average price | $558 Average price (fuel + tolls) |
67h 50m Average total duration 67h 20m Onboard + 30m Additional time* | 68h 35m Average total duration 68h 5m Onboard + 30m Additional time* | 12h 45m Average total duration Fastest 9h 45m Onboard + 3h 0m Additional time* | 40h 47m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Harrisburg, PA to San Francisco, CA is a bus with an average price of $282 (€232).
This is compared to other travel options from Harrisburg, PA to San Francisco, CA:
A bus is $212 (€174) less than a flight for this route with tickets for a flight from Harrisburg, PA to San Francisco, CA costing on average $493 (€406).
A bus is $2585 (€2126) less than a train for this route with tickets for a train from Harrisburg, PA to San Francisco, CA costing on average $2867 (€2357).
The fastest way to travel from Harrisburg, PA to San Francisco, CA is by flight with an average journey time of 9h 45m.
Other travel options to San Francisco, CA take longer:
Bus takes on average 67h 20m.
Train takes on average 68h 5m.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and San Francisco, CA including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to San Francisco, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Harrisburg, PA to San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:05AM | Arrival Time 07:25PM | Duration 67h20 | Departure days Wed, Fri | Cheapest price $241 |
Operator Greyhound | Departure Time 01:05AM | Arrival Time 08:25PM | Duration 67h20 | Departure days Sat | Cheapest price $239 |
Operator Greyhound USA | Departure Time 02:50PM | Arrival Time 07:15AM | Duration 64h25 | Departure days Wed | Cheapest price $832 |
Operator Greyhound USA | Departure Time 07:45PM | Arrival Time 12:25PM | Duration 64h40 | Departure days Wed | Cheapest price $771 |
Live departures
Harrisburg, PA to San Francisco, CA bus times
The table below shows live departures for Harrisburg, PA to San Francisco, CA buses for tomorrow, Wednesday, July 22. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 2:50 PM Harrisburg, PA | 64h25 | 7:15 AM San Francisco, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Wed
Jul 22
Jul 22
Thu
Jul 23
Jul 23
Fri
Jul 24
Jul 24
Sat
Jul 25
Jul 25
Sun
Jul 26
Jul 26
Mon
Jul 27
Jul 27
Tue
Jul 28
Jul 28
Why should you book Harrisburg, PA to San Francisco, CA buses with Omio?
Greyhound operates all buses services from Harrisburg, PA to San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Harrisburg, PA to San Francisco, CA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Harrisburg, PA to San Francisco, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Harrisburg, PA to San Francisco, CA.
Journey information
Overview: Bus from Harrisburg, PA to San Francisco, CA
USAUSA
Buses from Harrisburg, PA to San Francisco, CA run on average 4 times per day, taking around 67h 20m. Cheap bus tickets for this journey start at $239 (€197) if you book in advance.
The earliest bus runs at 07:00, the last at 23:25. The fastest bus covers the 2423 miles (3900 km) distance in 67h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 2423 miles (3900 km) |
Average bus duration 67h 20m |
Cheapest ticket price $239 (€197) |
Buses per day 4 |
Fastest bus 67h 20m |
First bus 7:00 AM |
Last bus 11:25 PM |
Cheapest Month Dec |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Harrisburg, PA to San Francisco, CAYou can travel by bus between Harrisburg, PA to San Francisco, CA with Greyhound for as low as $239 (€197). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
67h 20m
Cheapest Price
$239 (€197)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to San Francisco
Things to do in San Francisco
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
- Must visit
de Young Museum
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
- Must visit
San Francisco Museum of Modern Art
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
- Must visit
Golden Gate Park
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
- Must visit
Lombard Street
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
- Must visit
The Embarcadero
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
- Vegetarian
- Vegan
San Francisco Sourdough
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
- Gluten-free
Dungeness Crab
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
Cioppino
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Benu
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Sotto Mare
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
La Taqueria
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
US Dollar ($)
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Average meal costs
- Budget
- $12-20 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $90+ per person for upscale dining.
- Coffee
- $4-7 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
FAQs: Bus from Harrisburg, PA to San Francisco, CA
Find answers to the most common questions about traveling from Harrisburg, PA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Harrisburg, PA to San Francisco, CA can start from as little as $239 (€197) when you book in advance. The average bus ticket price for Harrisburg, PA to San Francisco, CA is $282 (€232) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to San Francisco, CA is 67h 20m to travel the 2423 miles (3900 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to San Francisco, CA leaves at 7:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to San Francisco, CA leaves at 11:25 PM.
There are 4 buses a day from Harrisburg, PA to San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Harrisburg, PA to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus companies who offer a service between Harrisburg, PA and San Francisco, CA and compare the amenities they offer before buying a bus ticket.
A trip to San Francisco, CA from Harrisburg, PA is worth doing but not as a day trip with a journey time of 67h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Harrisburg, PA to San Francisco, CA is December.
It's helpful to compare your options as there are 3 ways to travel between Harrisburg, PA and San Francisco, CA including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Harrisburg, PA to San Francisco, CA for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to San Francisco, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in San Francisco, CA are:
- Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
- Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
- Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
- Golden Gate Park, a large urban park with gardens, museums, and recreational activities
- Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
- Ride a cable car through the steep streets of San Francisco for a classic city experience
- Explore the vibrant murals and street art in the Mission District
- Visit the Exploratorium, an interactive science museum perfect for all ages
- Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
- Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
Whether you can cancel your bus ticket from Harrisburg, PA to San Francisco, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Harrisburg, PA to San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to San Francisco, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to San Francisco, CA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to San Francisco, CA.
You can reserve your seat on the bus from Harrisburg, PA to San Francisco, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Harrisburg, PA to San Francisco, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Harrisburg, PA to San Francisco, CA with the following bus company: Greyhound.
Since neither Harrisburg, PA nor San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Harrisburg, PA to San Francisco, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Harrisburg, PA to San Francisco, CA
Most Harrisburg, PA to San Francisco, CA buses use the Harrisburg, Market St (Bus Station) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Harrisburg, PA and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Harrisburg
Arrival bus stations in San Francisco
Harrisburg, Market St (Bus Station)
City-centre transport
Getting to Harrisburg, Market St (Bus Station) from Harrisburg city centre
Bus6/13, W · 29m · $4 · every ~4 min
Harrisburg, Chestnut Street / South 4th Street
City-centre transport
Getting to Harrisburg, Chestnut Street / South 4th Street from Harrisburg city centre
Bus2, 7, 81X, A, B, C, D, M, E · 8m · $2 · every ~6 min
2, M, 7, D, A, B, 81X, C, 322, E · 9m · $2 · every ~6 min
Hbg Com Kng B · 15m · $2
San Francisco, Transit Center Bay 29
City-centre transport
Getting to San Francisco, Transit Center Bay 29 from San Francisco city centre
Bus397 · 8m · $2
14, 14R · 13m · $2 · every ~30 min
101, 120 · 14m · $6 · every ~9 min
7 · 21m · $2 · every ~10 min
SubwayYellow-N, Green-N, Red-N, Blue-N · 10m · $2 · every ~27 min
San Francisco, Townsend Street / 5th StreetSan Francisco Bus Station,401 Townsend St,94107
City-centre transport
Getting to San Francisco, Townsend Street / 5th Street from San Francisco city centre
BusEast, West · 20m · every ~4 min
Nbus, Nowl · 24m · $2 · every ~2 min
TramN · 23m · $2 · every ~11 min
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to San Francisco, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Francisco, CA and Harrisburg, PA
Most popular bus connections to San Francisco, CA
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
