The cheapest and fastest buses from Harrisburg, PA to San Francisco, CA
Cheapest price
$241
Average price
$242
Fastest journey
2 d 19 h 20 m
Average duration
2 d 19 h 45 m
Buses per day
2
Distance
3900 km
The best way to find a cheap bus ticket from Harrisburg, PA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to San Francisco, CA will cost around $242 if you buy it on the day, but the cheapest tickets can be found for only $241.
Of the 2 buses that leave Harrisburg, PA for San Francisco, CA on Fri, Mar 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Mar 06 the direct buses cover the 3900 km distance in an average of 2 d 19 h 45 m but if you time it right, some buses will get you there in just 2 d 19 h 20 m .
On Fri, Mar 06 the slowest buses will take 2 d 20 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Harrisburg, PA to San Francisco, CA
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $241. For those with little time consider booking a flight which can get you there in 10h 34m. The ticket price range depends on the travel mode: a bus costs an average of $241, and a train costs an average of $301.
Distance: 2423 miles (3900 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$261 Average price Cheapest | $1586 Average price | $405 Average price |
68h 3m Average total duration 67h 33m Onboard + 30m Additional time* | 68h 35m Average total duration 68h 5m Onboard + 30m Additional time* | 13h 34m Average total duration Fastest 10h 34m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Harrisburg, PA to San Francisco, CA bus times
The table below shows live departures for Harrisburg, PA to San Francisco, CA buses for tomorrow, Friday, March 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:05 AM Harrisburg, PA | 67h20 | 8:25 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Why should you book Harrisburg, PA to San Francisco, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Harrisburg, PA to San Francisco, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Harrisburg, PA to San Francisco, CA.
Journey information
Overview: Bus from Harrisburg, PA to San Francisco, CA
Buses from Harrisburg, PA to San Francisco, CA run on average 4 times per day, taking around 67h 33m. Cheap bus tickets for this journey start at $241 (€195) if you book in advance.
The earliest bus runs at 07:00, the last at 23:25. The fastest bus covers the 2423 miles (3900 km) distance in 67h 10m.
Distance 2423 miles (3900 km) |
Average bus duration 67h 33m |
Cheapest ticket price $241 (€195) |
Buses per day 4 |
Fastest bus 67h 10m |
First bus 07:00 |
Last bus 23:25 |
Cheapest month Dec |
Cheapest day Fri |
High season Oct - Dec |
Low season Apr - Jun |
Bus providers: Greyhound from Harrisburg, PA to San Francisco, CAYou can travel by bus between Harrisburg, PA to San Francisco, CA with Greyhound for as low as $241 (€195). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Harrisburg, PA to San Francisco, CA
Find answers to the most common questions about traveling from Harrisburg, PA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
- Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
- Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
- Golden Gate Park, a large urban park with gardens, museums, and recreational activities
- Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
- Ride a cable car through the steep streets of San Francisco for a classic city experience
- Explore the vibrant murals and street art in the Mission District
- Visit the Exploratorium, an interactive science museum perfect for all ages
- Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
- Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Harrisburg, PA to San Francisco, CA
Most popular bus connections from Harrisburg, PA
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