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Travel Information
Compare bus, train, and flight for Greenville, SC to Durham, NC
Omio recommends booking the train as it is the most popular option from Greenville, SC to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from $47. For those with little time consider booking a flight which can get you there in 5h 19m. The ticket price range depends on the travel mode: a bus costs an average of $47, and a flight costs an average of $315.
Distance: 211 miles (341 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$66 Average price Cheapest | $80 Average price | $380 Average price | $50 Average price (fuel + tolls) |
5h 53m Average total duration 5h 23m Onboard + 30m Additional time* | 6h 30m Average total duration 6h 0m Onboard + 30m Additional time* | 8h 19m Average total duration Fastest 5h 19m Onboard + 3h 0m Additional time* | 3h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Durham, NC:
A bus is $13 (€11) less than a train for this route with tickets for a train from Greenville, SC to Durham, NC costing on average $80 (€64).
A bus is $314 (€251) less than a flight for this route with tickets for a flight from Greenville, SC to Durham, NC costing on average $380 (€304).
Other travel options to Durham, NC take longer:
Bus takes on average 5h 23m.
Train takes on average 6h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Live departures
Greenville, SC to Durham, NC bus times
The table below shows live departures for Greenville, SC to Durham, NC buses for today, Thursday, May 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 9:15 PM Greenville, SC | 4h55 | 2:10 AM Durham, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Durham, NC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Greenville, SC to Durham, NC
USAUSA
Buses from Greenville, SC to Durham, NC run on average 4 times per day, taking around 5h 23m. Cheap bus tickets for this journey start at $47 (€37) if you book in advance.
There are 3 buses per day. The earliest bus runs at 03:50, the last at 22:05. The fastest bus covers the 211 miles (341 km) distance in 4h 35m.
Distance 211 miles (341 km) |
Average bus duration 5h 23m |
Cheapest ticket price $47 (€37) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 4h 35m |
First bus 3:50 AM |
Last bus 10:05 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
FAQs: Bus from Greenville, SC to Durham, NC
Find answers to the most common questions about traveling from Greenville, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Greenville, SC to Durham, NC
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Durham, NC
Here are some other resources that might have the information you need
Most popular buses to and from Durham, NC and Greenville, SC
Most popular bus connections to Durham, NC
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