4.9
4.6The cheapest and fastest buses from Greenville, SC to Durham, NC
Cheapest price
$55
Average price
$55
Fastest journey
4 h 35 m
Average duration
4 h 35 m
Buses per day
1
Distance
341 km
The best way to find a cheap bus ticket from Greenville, SC to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Durham, NC will cost around $55 if you buy it on the day, but the cheapest tickets can be found for only $55.
Of the 1 buses that leave Greenville, SC for Durham, NC on Tue, Jun 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jun 23 the direct buses cover the 341 km distance in an average of 4 h 35 m but if you time it right, some buses will get you there in just 4 h 35 m .
On Tue, Jun 23 the slowest buses will take 4 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:00 AM4h35Greenville, SC7:35 AMDurham, NC$551One-way0 transfers
- 3:00 AM4h35Greenville, SC7:35 AMDurham, NC$551One-way0 transfers
Travel Information
Compare bus, train, and flight for Greenville, SC to Durham, NC
Omio recommends booking the train as it is the most popular option from Greenville, SC to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from $36. For those with little time consider booking a flight which can get you there in 3h 59m. The ticket price range depends on the travel mode: a bus costs an average of $36, and a flight costs an average of $235.
Distance: 211 miles (341 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$58 Average price Cheapest | $87 Average price | $347 Average price | $49 Average price (fuel + tolls) |
5h 49m Average total duration 5h 19m Onboard + 30m Additional time* | 6h 30m Average total duration 6h 0m Onboard + 30m Additional time* | 6h 59m Average total duration Fastest 3h 59m Onboard + 3h 0m Additional time* | 3h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Durham, NC:
A bus is $29 (€24) less than a train for this route with tickets for a train from Greenville, SC to Durham, NC costing on average $87 (€71).
A bus is $289 (€236) less than a flight for this route with tickets for a flight from Greenville, SC to Durham, NC costing on average $347 (€284).
Other travel options to Durham, NC take longer:
Bus takes on average 5h 19m.
Train takes on average 6h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Greenville, SC to Durham, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 06:35AM | Duration 4h35 | Departure days Sat | Cheapest price $38 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 07:35AM | Duration 4h35 | Departure days Tue | Cheapest price $55 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 09:00AM | Duration 5h35 | Departure days Sun | Cheapest price $71 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 02:10PM | Duration 7h00 | Departure days Sun | Cheapest price $75 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 08:55PM | Duration 8h45 | Departure days Tue | Cheapest price $126 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 05:00PM | Duration 4h45 | Departure days Sun | Cheapest price $57 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 09:10PM | Duration 4h55 | Departure days Sun | Cheapest price $57 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 01:10AM | Duration 4h55 | Departure days Wed, Thu, Fri, Sat | Cheapest price $36 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 02:10AM | Duration 4h35 | Departure days Sun | Cheapest price $68 |
Live departures
Greenville, SC to Durham, NC bus times
The table below shows live departures for Greenville, SC to Durham, NC buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 · | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 7h00 | 2:10 PM Durham Station | 1 transfer | |
| FlixBus | 12:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 4h45 | 5:00 PM Durham Station | 0 transfersDirect | |
| FlixBus | 4:15 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 4h55 | 9:10 PM Durham Station | 0 transfersDirect | |
| FlixBus | 9:35 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 4h35 | 2:10 AM Durham Station | 0 transfersDirect | |
| Monday, June 22 | |||||
| 3:00 AM Greenville, SC | 4h35 | 7:35 AM Durham, NC | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Durham, NC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 22
Jun 23
Jun 24
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Jun 28
Journey information
Overview: Bus from Greenville, SC to Durham, NC
USAUSA
Buses from Greenville, SC to Durham, NC run on average 3 times per day, taking around 5h 19m. Cheap bus tickets for this journey start at $36 (€29) if you book in advance.
There are 3 buses per day. The earliest bus runs at 03:55, the last at 22:05. The fastest bus covers the 211 miles (341 km) distance in 4h 35m.
Distance 211 miles (341 km) |
Average bus duration 5h 19m |
Cheapest ticket price $36 (€29) |
Buses per day 3 |
Direct buses 3 |
Fastest bus 4h 35m |
First bus 3:55 AM |
Last bus 10:05 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
FAQs: Bus from Greenville, SC to Durham, NC
Find answers to the most common questions about traveling from Greenville, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Greenville, SC to Durham, NC
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Durham, NC
Here are some other resources that might have the information you need
Most popular buses to and from Durham, NC and Greenville, SC
Most popular bus connections to Durham, NC
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