- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
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The cheapest and fastest buses from Greenville, SC to Durham, NC
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
$50
Average ticket price on Sep 20
$52
Fastest journey on Sep 20
4 h 35 m
Average journey duration on Sep 20
5 h 21 m
Buses on Sep 20
5
Distance
341 km
Cheap tickets
The best way to find a cheap bus ticket from Greenville, SC to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Durham, NC will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $50.
Fast buses
On Sun, Sep 20, we found 5 buses from Greenville, SC to Durham, NC, including 4 direct services.
On Sun, Sep 20 the direct buses cover the 341 km distance in an average of 5 h 21 m but if you time it right, some buses will get you there in just 4 h 35 m .
On Sun, Sep 20 the slowest buses will take 7 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus9:35 PM4h35Greenville, Woodruff Rd ("Raceway" gas station), SC2:10 AMDurham Station$501One-way0 transfers- FlixBus12:55 PM4h40Greenville, Woodruff Rd ("Raceway" gas station), SC5:35 PMDurham Station$501One-way0 transfers
- FlixBus4:15 PM4h55Greenville, Woodruff Rd ("Raceway" gas station), SC9:10 PMDurham Station$501One-way0 transfers
3:25 AM5h35Greenville, Woodruff Rd ("Raceway" gas station), SC9:00 AMDurham Station$511One-way0 transfers- · 7:10 AM7h00Greenville, Woodruff Rd ("Raceway" gas station), SC2:10 PMDurham Station$601One-way1 transfer
- FlixBus9:35 PM4h35Greenville, Woodruff Rd ("Raceway" gas station), SC2:10 AMDurham Station$501One-way0 transfers
- FlixBus12:55 PM4h40Greenville, Woodruff Rd ("Raceway" gas station), SC5:35 PMDurham Station$501One-way0 transfers
- FlixBus4:15 PM4h55Greenville, Woodruff Rd ("Raceway" gas station), SC9:10 PMDurham Station$501One-way0 transfers
- 3:25 AM5h35Greenville, Woodruff Rd ("Raceway" gas station), SC9:00 AMDurham Station$511One-way0 transfers
- · 7:10 AM7h00Greenville, Woodruff Rd ("Raceway" gas station), SC2:10 PMDurham Station$601One-way1 transfer
Greenville, SC to Durham, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 06:35AM | Duration 4h35 | Departure days Sat | Cheapest price $38 |
Operator Greyhound | Departure Time 03:25AM | Arrival Time 09:00AM | Duration 5h35 | Departure days Mon, Sun | Cheapest price $51 |
Operator Greyhound | Departure Time 07:10AM | Arrival Time 02:10PM | Duration 7h00 | Departure days Mon, Sun | Cheapest price $60 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 08:55PM | Duration 8h45 | Departure days Tue | Cheapest price $126 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 05:35PM | Duration 4h40 | Departure days Mon, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 09:10PM | Duration 4h55 | Departure days Mon, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 01:10AM | Duration 4h55 | Departure days Wed, Thu, Fri, Sat | Cheapest price $36 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 02:10AM | Duration 4h35 | Departure days Mon, Sun | Cheapest price $44 |
Live departures
Greenville, SC to Durham, NC bus times
The table below shows live departures for Greenville, SC to Durham, NC buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:15 PM Greenville, SC | 4h55 | 1:10 AM Durham, NC | 0 transfersDirect | |
| Sunday, September 20 | |||||
| 3:25 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 5h35 | 9:00 AM Durham Station | 0 transfersDirect | |
| · | 7:10 AM Greenville, Woodruff Rd ("Raceway" gas station), SC | 7h00 | 2:10 PM Durham Station | 1 transfer | |
| FlixBus | 12:55 PM Greenville, Woodruff Rd ("Raceway" gas station), SC | 4h40 | 5:35 PM Durham Station | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Durham, NC by bus
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Journey information
Overview: Bus from Greenville, SC to Durham, NC
USAUSA
Take a bus from Greenville, SC to Durham, NC and enjoy the approximately 211 miles (341 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 03:55, the last at 22:05.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 211 miles (341 km) |
First bus 3:55 AM |
Last bus 10:05 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Durham, NC
Things to do in Durham, NC
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
- Must visit
Museum of Life and Science
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
- Recommended
Duke Homestead State Historic Site
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
- Must visit
Sarah P. Duke Gardens
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
- Must visit
Downtown Durham
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
- Must visit
American Tobacco Trail
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
- Gluten-free
Eastern NC Pork Barbecue
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Pulled Pork Plate
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
- Vegetarian
Hush Puppies
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
M Pocha
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Guglhupf Bakery & Cafe
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
True Flavors Diner
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
US Dollar ($)
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-40 per person for a mid-range meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
FAQs: Bus from Greenville, SC to Durham, NC
Find answers to the most common questions about traveling from Greenville, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Greenville, SC to Durham, NC
Most Greenville, SC to Durham, NC buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Greenville, SC and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Greenville
Arrival bus stations in Durham
Which Greenville, SC station do buses to Durham, NC leave from?
Buses from Greenville, SC to Durham, NC leave from Greenville, Woodruff Rd ("Raceway" gas station). The station is 4 miles (8 km) from Greenville, SC city centre at Woodruff Rd, Greenville, SC, USA.
Greenville, Woodruff Rd ("Raceway" gas station)Woodruff Rd, Greenville, SC, USA
City-centre transport
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
TRUE
Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Durham, W Pettigrew St (Greyhound Bus Station)Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701
City-centre transport
Getting to Durham, W Pettigrew St (Greyhound Bus Station) from Durham city centre
Bus2, 9, 12, 12B · 5m · $1 · every ~12 min
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Durham, NC
Here are some other resources that might have the information you need
Most popular buses to and from Durham, NC and Greenville, SC
Most popular bus connections to Durham, NC
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