- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
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The cheapest and fastest buses from Greenville, SC to Durham, NC
Showing times and prices for Aug 06
Cheapest price
$36
Average price
$36
Fastest journey
4 h 55 m
Average duration
4 h 55 m
Buses per day
1
Distance
341 km
Cheap tickets
The best way to find a cheap bus ticket from Greenville, SC to Durham, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to Durham, NC will cost around $36 if you buy it on the day, but the cheapest tickets can be found for only $36.
Fast buses
Of the 1 buses that leave Greenville, SC for Durham, NC on Thu, Aug 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 341 km distance in an average of 4 h 55 m but if you time it right, some buses will get you there in just 4 h 55 m .
On Thu, Aug 06 the slowest buses will take 4 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
8:15 PM4h55Greenville, SC1:10 AMDurham, NC$361One-way0 transfers
- 8:15 PM4h55Greenville, SC1:10 AMDurham, NC$361One-way0 transfers
Travel Information
Compare bus, train, and flight for Greenville, SC to Durham, NC
Omio recommends booking the train as it is the most popular option from Greenville, SC to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from $36. For those with little time consider booking a flight which can get you there in 3h 59m. The ticket price range depends on the travel mode: a bus costs an average of $36, and a flight costs an average of $237.
Distance: 211 miles (341 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$59 Average price Cheapest | $88 Average price | $349 Average price | $49 Average price (fuel + tolls) |
5h 49m Average total duration 5h 19m Onboard + 30m Additional time* | 6h 30m Average total duration 6h 0m Onboard + 30m Additional time* | 6h 59m Average total duration Fastest 3h 59m Onboard + 3h 0m Additional time* | 3h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to Durham, NC is a bus with an average price of $59.
This is compared to other travel options from Greenville, SC to Durham, NC:
A bus is $29 less than a train for this route with tickets for a train from Greenville, SC to Durham, NC costing on average $88.
A bus is $290 less than a flight for this route with tickets for a flight from Greenville, SC to Durham, NC costing on average $349.
The fastest way to travel from Greenville, SC to Durham, NC is by flight with an average journey time of 3h 59m.
Other travel options to Durham, NC take longer:
Bus takes on average 5h 19m.
Train takes on average 6h 0m.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Durham, NC including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Greenville, SC to Durham, NC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Greenville, SC to Durham, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 06:35AM | Duration 4h35 | Departure days Sat | Cheapest price $38 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 07:35AM | Duration 4h35 | Departure days Tue | Cheapest price $55 |
Operator Greyhound | Departure Time 12:10PM | Arrival Time 08:55PM | Duration 8h45 | Departure days Tue | Cheapest price $127 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 01:10AM | Duration 4h55 | Departure days Wed, Thu, Fri, Sat | Cheapest price $36 |
Live departures
Greenville, SC to Durham, NC bus times
The table below shows live departures for Greenville, SC to Durham, NC buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:15 PM Greenville, SC | 4h55 | 1:10 AM Durham, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to Durham, NC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Greenville, SC to Durham, NC
USAUSA
Buses from Greenville, SC to Durham, NC run on average 3 times per day, taking around 5h 19m. Cheap bus tickets for this journey start at $36 if you book in advance.
There are 3 buses per day. The earliest bus runs at 03:55, the last at 22:05. The fastest bus covers the 211 miles (341 km) distance in 4h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 211 miles (341 km) |
Average bus duration 5h 19m |
Cheapest ticket price $36 |
Buses per day 3 |
Direct buses 3 |
Fastest bus 4h 35m |
First bus 3:55 AM |
Last bus 10:05 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Complete guide to Durham, NC
Things to do in Durham, NC
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
- Must visit
Museum of Life and Science
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
- Recommended
Duke Homestead State Historic Site
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
- Must visit
Sarah P. Duke Gardens
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
- Must visit
Downtown Durham
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
- Must visit
American Tobacco Trail
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
- Gluten-free
Eastern NC Pork Barbecue
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Pulled Pork Plate
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
- Vegetarian
Hush Puppies
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
M Pocha
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Guglhupf Bakery & Cafe
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
True Flavors Diner
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
US Dollar ($)
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-40 per person for a mid-range meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
FAQs: Bus from Greenville, SC to Durham, NC
Find answers to the most common questions about traveling from Greenville, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Greenville, SC to Durham, NC can start from as little as $36 when you book in advance. The average bus ticket price for Greenville, SC to Durham, NC is $59 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Durham, NC is 4h 35m to travel the 211 miles (341 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Durham, NC leaves at 3:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Durham, NC leaves at 10:05 PM.
When departing from Greenville, SC , you have various bus station options to start your journey from including Greenville, Woodruff Rd ("Raceway" gas station), SC . When arriving in Durham, NC , you can end your journey in bus stations like Durham Station, Chapel Hill, Myrica St / Eubanks Rd, NC .Passengers board the bus most frequently from Greenville, Woodruff Rd ("Raceway" gas station), SC, which is located around 4 miles (8 km) away from the city centre, and they get off the bus at Durham Station, located 0 away from the city centre.
A trip to Durham, NC from Greenville, SC is worth doing but not as a day trip with a journey time of 4h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Durham, NC is May.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Durham, NC including taking a bus, train, and flight.
No, there are no bathrooms on board the bus from Greenville, SC to Durham, NC.
No, the bus from Greenville, SC to Durham, NC has no accessibility options.
No, bikes are not allowed on board the bus from Greenville, SC to Durham, NC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Greenville, SC to Durham, NC.
No, luggage for the bus from Greenville, SC to Durham, NC needs to be booked in addition.
No, there are no additional luggage options for the bus from Greenville, SC to Durham, NC.
Unfortunately, pets are not allowed on the bus from Greenville, SC to Durham, NC.
No, there are no USB plugs on board the bus from Greenville, SC to Durham, NC.
No, there is no WiFi on board the bus from Greenville, SC to Durham, NC.
Since neither Greenville, SC nor Durham, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Greenville, SC to Durham, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Durham, NC, travelers should stay alert to common urban safety concerns such as petty theft, especially in crowded areas and public transit. Scams may include overcharging by unofficial taxi services or ride-share drivers, so using reputable transportation apps is advised. It's also important to avoid isolated areas after dark and keep personal belongings secure to reduce risk.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Greenville, SC to Durham, NC
Most Greenville, SC to Durham, NC buses use the Greenville, Woodruff Rd ("Raceway" gas station) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Greenville, SC and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Greenville
Arrival bus stations in Durham
Which Greenville, SC station do buses to Durham, NC leave from?
Buses from Greenville, SC to Durham, NC leave from Greenville, Woodruff Rd ("Raceway" gas station). The station is 4 miles (8 km) from Greenville, SC city centre at Woodruff Rd, Greenville, SC, USA.
Greenville, Woodruff Rd ("Raceway" gas station)Woodruff Rd, Greenville, SC, USA
City-centre transport
Getting to Greenville, Woodruff Rd ("Raceway" gas station) from Greenville city centre
Greenville, Woodruff Rd ("Raceway" gas station) is 8 km from Greenville city centre. Public transport options include:
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Greenville, Woodruff Rd ("Raceway" gas station) bus station facilities and services
Greenville, Woodruff Rd ("Raceway" gas station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Limited dining options available in adjacent areas.
Wi-Fi and ATMs
Wi-Fi is available at Greenville, Woodruff Rd ("Raceway" gas station). ATMs are available at Greenville, Woodruff Rd ("Raceway" gas station).
Tickets and information
Ticket office support is available at Greenville, Woodruff Rd ("Raceway" gas station).
Parking, taxis and toilets
Available at Greenville, Woodruff Rd ("Raceway" gas station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, Woodruff Rd ("Raceway" gas station): Basic access available for persons with disabilities.
Durham, W Pettigrew St (Greyhound Bus Station)Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701
City-centre transport
Getting to Durham, W Pettigrew St (Greyhound Bus Station) from Durham city centre
Bus2, 9, 12, 12B · 5m · $1 · every ~12 min
Most popular bus connections from Greenville, SC
More options for your journey from Greenville, SC to Durham, NC
Here are some other resources that might have the information you need
Most popular buses to and from Durham, NC and Greenville, SC
Most popular bus connections to Durham, NC
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