Greenville, SC to Durham, NC bus

Fri, May 08
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FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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Travel Information

Compare bus, train, and flight for Greenville, SC to Durham, NC

Omio recommends booking the train as it is the most popular option from Greenville, SC to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from $47. For those with little time consider booking a flight which can get you there in 5h 19m. The ticket price range depends on the travel mode: a bus costs an average of $47, and a flight costs an average of $315.

Distance: 211 miles (341 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$66

Average price

Cheapest

$80

Average price

$380

Average price

$50

Average price

(fuel + tolls)

5h 53m

Average total duration

5h 23m

Onboard

+

30m

Additional time*

6h 30m

Average total duration

6h 0m

Onboard

+

30m

Additional time*

8h 19m

Average total duration

Fastest

5h 19m

Onboard

+

3h 0m

Additional time*

3h 30m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Greenville, SC to Durham, NC is a bus with an average price of $66 (€53).

This is compared to other travel options from Greenville, SC to Durham, NC:

A bus is $13 (€11) less than a train for this route with tickets for a train from Greenville, SC to Durham, NC costing on average $80 (€64).

A bus is $314 (€251) less than a flight for this route with tickets for a flight from Greenville, SC to Durham, NC costing on average $380 (€304).

The fastest way to travel from Greenville, SC to Durham, NC is by flight with an average journey time of 5h 19m.

Other travel options to Durham, NC take longer:

Bus takes on average 5h 23m.

Train takes on average 6h 0m.

It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Durham, NC including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Greenville, SC to Durham, NC among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Live departures

Greenville, SC to Durham, NC bus times

The table below shows live departures for Greenville, SC to Durham, NC buses for today, Thursday, May 7. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus9:15 PM Greenville, SC
4h55
2:10 AM Durham, NC0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Greenville, SC to Durham, NC by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
May 08
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Journey information

Overview: Bus from Greenville, SC to Durham, NC

USAUSA
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Icon of bus

Buses from Greenville, SC to Durham, NC run on average 4 times per day, taking around 5h 23m. Cheap bus tickets for this journey start at $47 (€37) if you book in advance.

There are 3 buses per day. The earliest bus runs at 03:50, the last at 22:05. The fastest bus covers the 211 miles (341 km) distance in 4h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
211 miles (341 km)
Average bus duration
5h 23m
Cheapest ticket price
$47 (€37)
Buses per day
4
Direct buses
3
Fastest bus
4h 35m
First bus
3:50 AM
Last bus
10:05 PM
Cheapest Month
May
Cheapest Day
Mon
High Season
Jan - Mar
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Greenville, SC to Durham, NC

Find answers to the most common questions about traveling from Greenville, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Greenville, SC to Durham, NC can start from as little as $47 (€37) when you book in advance. The average bus ticket price for Greenville, SC to Durham, NC is $66 (€53) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Greenville, SC to Durham, NC is 4h 35m to travel the 211 miles (341 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Greenville, SC to Durham, NC leaves at 3:50 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Greenville, SC to Durham, NC leaves at 10:05 PM.
A trip to Durham, NC from Greenville, SC is worth doing but not as a day trip with a journey time of 4h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Greenville, SC to Durham, NC is May.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and Durham, NC including taking a bus, train, and flight.
No, the bus from Greenville, SC to Durham, NC has no accessibility options.
No, there are no bathrooms on board the bus from Greenville, SC to Durham, NC.
No, bikes are not allowed on board the bus from Greenville, SC to Durham, NC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Greenville, SC to Durham, NC.
No, luggage for the bus from Greenville, SC to Durham, NC needs to be booked in addition.
No, there are no additional luggage options for the bus from Greenville, SC to Durham, NC.
Unfortunately, pets are not allowed on the bus from Greenville, SC to Durham, NC.
No, there are no USB plugs on board the bus from Greenville, SC to Durham, NC.
No, there is no WiFi on board the bus from Greenville, SC to Durham, NC.
Since neither Greenville, SC nor Durham, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Greenville, SC to Durham, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Durham, NC, travelers should stay alert to common urban safety concerns such as petty theft, especially in crowded areas and public transit. Scams may include overcharging by unofficial taxi services or ride-share drivers, so using reputable transportation apps is advised. It's also important to avoid isolated areas after dark and keep personal belongings secure to reduce risk.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Greenville, SC to Durham, NC

Greenville
Durham
The major bus station for departures in Greenville is Greenville, Woodruff Rd ("Raceway" gas station). Find all the information you need to know about services, amenities and connections at Greenville, Woodruff Rd ("Raceway" gas station) for your trip from Greenville to Durham.
Greenville, Woodruff Rd ("Raceway" gas station)
information

More options for your journey from Greenville, SC to Durham, NC

Here are some other resources that might have the information you need

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