- Must visit
Everson Museum of Art
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
The best way to find a cheap bus ticket from Denver, CO to Syracuse, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Denver, CO to Syracuse, NY will cost around $276 if you buy it on the day, but the cheapest tickets can be found for only $276.
On Tue, Nov 03, we found 1 buses from Denver, CO to Syracuse, NY, including 1 direct services.
On Tue, Nov 03 the direct buses cover the 2421 km distance in an average of 1 d 23 h 30 m but if you time it right, some buses will get you there in just 1 d 23 h 30 m .
On Tue, Nov 03 the slowest buses will take 1 d 23 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Denver, CO to Syracuse, NY run on average 1 times per day, taking around 35h 34m. Cheap bus tickets for this journey start at $166 if you book in advance.
The earliest bus runs at 01:15, the last at 21:00. The fastest bus covers the 1504 miles (2421 km) distance in 34h 30m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Denver, CO to Syracuse, NY.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 12:25AM | Duration 47h30 | Departure days Tue | Cheapest price $276 |
Operator Greyhound | Departure Time 01:55AM | Arrival Time 01:25AM | Duration 47h30 | Departure days Sat, Sun | Cheapest price $229 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 11:20AM | Duration 38h25 | Departure days Tue, Wed, Thu, Sun | Cheapest price $140 |
The table below shows live departures for Denver, CO to Syracuse, NY buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:55 AM Denver, CO | 47h30 | 12:25 AM Syracuse, NY | 0 transfersDirect | |
| Sunday, November 1 | |||||
· · | 6:55 PM Denver, Union Station | 38h25 | 11:20 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Denver, CO to Syracuse, NY with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Syracuse, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse, NY trip today.
Major regional museum covering art, science, and history. Best known for broad collections, family appeal, and exhibits on Central New York.
Historic house museum preserving nineteenth-century Syracuse domestic life. Worth visiting for period rooms and insight into early city society.
Interactive museum focused on science and technology, famous for hands-on exhibits and domed IMAX theater. Great for families and curious visitors.
Historic downtown square and year-round gathering place, known for festivals, fountains, and winter skating. A central stop for city atmosphere.
Scenic waterfront park with long trails, lake views, and birdlife. Popular for walking, cycling, and relaxing near Syracuse's restored shoreline.
Compact downtown district filled with galleries, murals, and restored warehouse buildings. Best explored on foot for arts culture and architecture.
Salt potatoes are small potatoes boiled in heavily salted water, creating a crusty skin and creamy center. They are a Central New York summer staple, often served with butter.
Chicken riggies is a spicy Utica pasta dish popular across Central New York, made with chicken, rigatoni, peppers, and a creamy tomato sauce.
Utica greens are escarole sautéed with hot peppers, garlic, breadcrumbs, and often prosciutto. This Italian American side is beloved throughout the Syracuse area.
Long running market cafe and bakery known for tomato pie, sandwiches, pastries, and a classic Syracuse neighborhood feel.
Established Italian restaurant known for homemade pasta, regional Italian American dishes, and a polished but welcoming atmosphere.
Upscale downtown dining with seasonal American cuisine, thoughtful plating, and a refined setting popular for special occasions.
Moderate for a U.S. city. Hotels are often cheaper than NYC, dining is mid-priced, and most visitors need a car or rideshares as transit is limited.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts for small tips.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Syracuse, NY.
Find answers to the most common questions about traveling from Denver, CO to Syracuse, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, NY, this guide helps you travel smarter and with confidence.

Most Denver, CO to Syracuse, NY buses use the Denver, Union Station to Syracuse, Walsh Cir (Syracuse Bus Station) station pair. Use this guide to compare Denver, CO and Syracuse, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.