The cheapest and fastest trains from Durham, NC to Greenville, SC
Cheapest price
$83
Average price
$83
Fastest journey
10 h 23 m
Average duration
10 h 52 m
Trains per day
2
Distance
341 km
The best way to find a cheap train ticket from Durham, NC to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Greenville, SC will cost around $83 if you buy it on the day, but the cheapest tickets can be found for only $83.
Of the 2 trains that leave Durham, NC for Greenville, SC on Sun, Nov 23, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Nov 23 the direct trains cover the 341 km distance in an average of 10 h 52 m but if you time it right, some trains will get you there in just 10 h 23 m .
On Sun, Nov 23 the slowest trains will take 11 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Durham, NC to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Durham, NC to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €35. For those with little time consider booking a bus which can get you there in 4h 52m. The ticket price range depends on the travel mode: a bus costs an average of €35, and a flight costs an average of €132.
Distance: 211 miles (341 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€64 Average price | €40 Average price Cheapest | €281 Average price |
11h 28m Average total duration 10h 58m Onboard + 30m Additional time* | 5h 22m Average total duration Fastest 4h 52m Onboard + 30m Additional time* | 8h 43m Average total duration 5h 43m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Durham, NC to Greenville, SC train times
The table below shows live departures for Durham, NC to Greenville, SC trains for today, Saturday, November 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
79 Carolinian · 19 Crescent | 11:04 PM Durham Station, Durham, NC | 11h20 | 10:24 AM Greenville Station, Greenville, SC | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Durham, NC to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 23
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Nov 29
Journey information
Overview: Train from Durham, NC to Greenville, SC
Trains from Durham, NC to Greenville, SC run on average 1 times per day, taking around 10h 58m. Cheap train tickets for this journey start at $70 (€57) but you can travel from only $44 (€35) by bus.
The earliest train runs at 02:23, the last at 18:18. The fastest train covers the 211 miles (341 km) distance in 10h 23m.
Distance 211 miles (341 km) |
Average train duration 10h 58m |
Cheapest ticket price $70 (€57) |
Trains per day 1 |
Fastest train 10h 23m |
First train 02:23 |
Last train 18:18 |
FAQs: Trains from Durham, NC to Greenville, SC
Find answers to the most common questions about traveling from Durham, NC to Greenville, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Durham, NC to Greenville, SC
- 6:30 AM - 9:00 PM Monday - Sunday
- Free
- Parking is available nearby, with several public parking options in the vicinity.
- Parker and Otis
- Dame's Chicken & Waffles
- Outside the main entrance.
- Ramps.
- Free of charge
- Durham Marriott City Center
- 21c Museum Hotel Durham
- Aloft Durham Downtown
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticketing, and waiting area
- Hall 2: platform access
- Bus: GoDurham buses available
- Amtrak Thruway buses
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available adjacent to the station, open 24/7.
- Soby's
- Larkin's on the River
- Outside the main entrance.
- Ramps, assistance.
- $1.00
- The Westin Poinsett, Greenville
- Courtyard Greenville Downtown
- Hyatt Regency Greenville
- Located in the main hall
- Located in the main hall
- Free
- The station has a single platform for Amtrak services and a waiting area.
- Bus: Greenlink Transit Route 3
- Taxi services available
Most popular train connections from Durham, NC
More options for your journey from Durham, NC to Greenville, SC
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