The cheapest and fastest buses from Durham, NC to Pittsburgh, PA
Cheapest price
$206
Average price
$225
Fastest journey
13 h 25 m
Average duration
14 h 45 m
Buses per day
3
Distance
504 km
The best way to find a cheap bus ticket from Durham, NC to Pittsburgh, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Pittsburgh, PA will cost around $225 if you buy it on the day, but the cheapest tickets can be found for only $206.
It's difficult to get from Durham, NC to Pittsburgh, PA without transferring at least once.






Travel Information
Compare bus, train, and flight for Durham, NC to Pittsburgh, PA
Omio recommends booking the train as it is the most popular option from Durham, NC to Pittsburgh, PA among Omio's users. If you are prioritising price take the bus with prices starting from €167. For those with little time consider booking a bus which can get you there in 14h 58m. The ticket price range depends on the travel mode: a bus costs an average of €167, and a train costs an average of €213.
Distance: 313 miles (504 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€190 Average price Cheapest | €219 Average price |
15h 28m Average total duration Fastest 14h 58m Onboard + 30m Additional time* | 30h 6m Average total duration 29h 36m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Durham, NC to Pittsburgh, PA bus times
The table below shows live departures for Durham, NC to Pittsburgh, PA buses for today, Friday, January 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 AM Durham, NC | 15h20 | 12:35 AM Pittsburgh, PA | 1 transfer | |
![]() | 5:05 PM Durham, NC | 13h25 | 6:30 AM Pittsburgh, PA | 1 transfer | |
![]() | 9:15 PM Durham, NC | 15h30 | 12:45 PM Pittsburgh, PA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Durham, NC to Pittsburgh, PA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Durham, NC to Pittsburgh, PA
Buses from Durham, NC to Pittsburgh, PA run on average 4 times per day, taking around 14h 58m. Cheap bus tickets for this journey start at $207 (€167) if you book in advance.
The earliest bus runs at 00:55, the last at 23:10. The fastest bus covers the 313 miles (504 km) distance in 13h 25m.
Distance 313 miles (504 km) |
Average bus duration 14h 58m |
Cheapest ticket price $207 (€167) |
Buses per day 4 |
Fastest bus 13h 25m |
First bus 00:55 |
Last bus 23:10 |
Bus providers: Greyhound, FlixBus from Durham, NC to Pittsburgh, PAYou can travel by bus between Durham, NC to Pittsburgh, PA with Greyhound, FlixBus for as low as $207 (€167). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Durham, NC to Pittsburgh, PA
Find answers to the most common questions about traveling from Durham, NC to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- The Andy Warhol Museum, a comprehensive collection dedicated to the life and works of the iconic pop artist
- Phipps Conservatory and Botanical Gardens, a historic greenhouse with diverse plant exhibits and sustainable architecture
- Carnegie Museum of Natural History, featuring extensive dinosaur displays and global cultural artifacts
- Point State Park, a scenic urban park at the confluence of three rivers with historical significance
- Mount Washington, offering panoramic views of Pittsburgh's skyline from its renowned overlooks.
- Heinz History Center, an affiliate of the Smithsonian Institution showcasing Western Pennsylvania's history and heritage
- Take a ride on the Duquesne Incline for a historic cable car experience and stunning city views
- Explore the Strip District, known for its vibrant markets, eateries, and unique shops
- Visit the National Aviary, home to a diverse collection of birds from around the world
- Enjoy a Pittsburgh Pirates game at PNC Park, renowned for its beautiful views of the city skyline.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Durham, NC to Pittsburgh, PA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Durham, NC to Pittsburgh, PA
Most popular bus connections from Durham, NC
More options for your journey from Durham, NC to Pittsburgh, PA
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