- Must visit
Cummer Museum of Art & Gardens
Major art museum with American and European works, a notable sculpture garden, and one of Jacksonville's top cultural stops.
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The cheapest and fastest buses from St. Louis, MO to Jacksonville, FL
Showing times and prices for Aug 05
Cheapest price
$108
Average price
$109
Fastest journey
20 h 35 m
Average duration
21 h 18 m
Buses per day
3
Distance
1209 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Jacksonville, FL will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $108.
Fast buses
It's difficult to get from St. Louis, MO to Jacksonville, FL without transferring at least once.
FlixBus+
+FlixBus4:00 PM20h35St. Louis, S 15th St (Civic center)1:35 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1081One-way2 transfers- FlixBus · FlixBus11:45 PM22h20St. Louis, S 15th St (Civic center)11:05 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1091One-way1 transfer
- +FlixBus9:00 AM21h00St. Louis, S 15th St (Civic center)7:00 AMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1101One-way1 transfer
- FlixBus++FlixBus4:00 PM20h35St. Louis, S 15th St (Civic center)1:35 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1081One-way2 transfers
- +FlixBus9:00 AM21h00St. Louis, S 15th St (Civic center)7:00 AMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1101One-way1 transfer
- FlixBus · FlixBus11:45 PM22h20St. Louis, S 15th St (Civic center)11:05 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$1091One-way1 transfer
Journey information
Overview: Bus from St. Louis, MO to Jacksonville, FL
USAUSA
Buses from St. Louis, MO to Jacksonville, FL run on average 3 times per day, taking around 23h 37m. Cheap bus tickets for this journey start at $140 if you book in advance.
The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 751 miles (1209 km) distance in 20h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 751 miles (1209 km) |
Average bus duration 23h 37m |
Cheapest ticket price $140 |
Buses per day 3 |
Fastest bus 20h 35m |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Dec |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
St. Louis, MO to Jacksonville, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:00AM | Arrival Time 07:00AM | Duration 21h00 | Departure days Everyday | Cheapest price $101 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 01:35PM | Duration 20h35 | Departure days Everyday | Cheapest price $100 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 11:05PM | Duration 22h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $101 |
Live departures
St. Louis, MO to Jacksonville, FL bus times
The table below shows live departures for St. Louis, MO to Jacksonville, FL buses for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| +FlixBus | 9:00 AM St. Louis, S 15th St (Civic center) | 21h00 | 7:00 AM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
| FlixBus++FlixBus | 4:00 PM St. Louis, S 15th St (Civic center) | 20h35 | 1:35 PM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book St. Louis, MO to Jacksonville, FL buses with Omio?
FlixBus operates all buses services from St. Louis, MO to Jacksonville, FL.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Jacksonville, FL.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Jacksonville, FL.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Jacksonville, FL.
Bus providers: FlixBus from St. Louis, MO to Jacksonville, FLYou can travel by bus between St. Louis, MO to Jacksonville, FL with FlixBus for as low as $140. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
22h 35m
Cheapest Price
$270
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Jacksonville, FL
Things to do in Jacksonville, FL
Discover the best of Jacksonville, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville, FL trip today.
- Recommended
Museum of Science & History
Regional history museum covering Northeast Florida through engaging exhibits on city growth, culture, and key local events.
- Recommended
Museum of Contemporary Art Jacksonville
Contemporary art museum in the university district, presenting rotating exhibitions and thoughtful programs by living artists.
- Must visit
Northbank Riverwalk
Lively riverfront district with museums, restaurants nearby, public art, and one of Jacksonville's best skyline strolls.
- Must visit
Southbank Riverwalk
Scenic promenade across the river from downtown, ideal for walks, bridge views, and sunset photos along the Southbank.
- Recommended
Five Points
Creative historic neighborhood known for murals, local shops, nightlife, and a walkable mix of old Jacksonville character.
- Gluten-free
Mayport Shrimp
Mayport shrimp are local Atlantic shrimp, prized for their sweet flavor. They are a Jacksonville seafood staple, often served fried, grilled, or in baskets near the coast.
- Gluten-free
Low Country Boil
A Low Country boil with shrimp, sausage, corn, and potatoes reflects Northeast Florida’s coastal Southern cooking and is popular at casual local seafood spots.
- Gluten-free
Florida Oysters
Fresh local oysters from nearby Florida waters are served raw, baked, or chargrilled. They are a classic Jacksonville choice tied to the region’s seafood culture.
Safe Harbor Seafood Restaurant
Popular casual seafood restaurant in Mayport, best known for fresh local shrimp, fried seafood platters, and a laid-back dockside feel.
Ruth's Chris Steak House
Refined riverfront steakhouse known for prime steaks, seafood, and polished service in an upscale setting on the Southbank.
Blue Fish Restaurant and Oyster Bar
Established upscale seafood restaurant with an extensive wine list, elegant atmosphere, and strong reputation for fresh fish and fine dining.
US dollar ($)
Moderate for US beach cities. Hotels vary by season; meals and coffee are typical US prices, and most visitors need a car as transit is limited.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $3-6 for drip coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually get 10-15%. Cafes often use tip jars or screens; $1-2 is common.
FAQs: Bus from St. Louis, MO to Jacksonville, FL
Find answers to the most common questions about traveling from St. Louis, MO to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Jacksonville, FL can start from as little as $140 when you book in advance. The average bus ticket price for St. Louis, MO to Jacksonville, FL is $197 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Jacksonville, FL is 20h 35m to travel the 751 miles (1209 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Jacksonville, FL leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Jacksonville, FL leaves at 11:30 PM.
There are 3 buses a day from St. Louis, MO to Jacksonville, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Jacksonville, FL, you can count on FlixBus for the best way to get you to Jacksonville, FL. You can also check all possible bus companies who offer a service between St. Louis, MO and Jacksonville, FL and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport . When arriving in Jacksonville, FL , you can end your journey in bus stations like Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St, located 1 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Jacksonville, FL including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from St. Louis, MO to Jacksonville, FL for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Jacksonville, FL:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from St. Louis, MO to Jacksonville, FL depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Jacksonville, FL.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Jacksonville, FL:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Jacksonville, FL:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Jacksonville, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Jacksonville, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Jacksonville, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Jacksonville, FL with the following bus company: FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Jacksonville, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots. Common scams include overcharging by unlicensed taxi or ride-share drivers and fake ticket sellers near attractions. Staying aware of surroundings, using reputable transportation services, and avoiding isolated areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Jacksonville, FL
Most St. Louis, MO to Jacksonville, FL buses use the St. Louis, S 15th St (Civic center) to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St station pair. Use this guide to compare St. Louis, MO and Jacksonville, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Jacksonville
Which St. Louis, MO station do buses to Jacksonville, FL leave from?
Buses from St. Louis, MO to Jacksonville, FL leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USA
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $31 · every ~4 min
St. Louis, Lambert International Airport bus station facilities and services
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options available in terminals.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Tickets and information
Ticket office support is available at St. Louis, Lambert International Airport.
Parking, taxis and toilets
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Which Jacksonville, FL station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to Jacksonville, FL arrive at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St is 1 miles (2 km) from Jacksonville, FL city centre.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St1111 W Forsyth St, Jacksonville, FL 32204, USA
City-centre transport
Getting to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St from Jacksonville city centre
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St is 1 km from Jacksonville city centre. Public transport options include:
Bus1, 11, 18, 205, 3, Nassau, St. Johns, Clay · 12m · $4 · every ~18 min
1, 19, 3 · 17m · $4 · every ~17 min
SubwaySky · 10m · every ~4 min
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St bus station facilities and services
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. ATMs are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Tickets and information
Ticket office support is available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St.
Parking, taxis and toilets
Available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St: Wheelchair accessible entrances.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Jacksonville, FL
Here are some other resources that might have the information you need
Most popular buses to and from Jacksonville, FL and St. Louis, MO
Most popular bus connections to Jacksonville, FL
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