Travel Information
Compare bus and flight for Charlotte, NC to San Diego, CA
Omio recommends booking the flight as it is the most popular option from Charlotte, NC to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €140. For those with little time consider booking a flight which can get you there in 5h 38m. The ticket price range depends on the travel mode: a bus costs an average of €140, and a flight costs an average of €175.
Distance: 2076 miles (3342 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
€232 Average price Cheapest | €245 Average price |
50h 25m Average total duration 49h 55m Onboard + 30m Additional time* | 8h 38m Average total duration Fastest 5h 38m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Compare prices and tickets Charlotte, NC to San Diego, CA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Charlotte, NC to San Diego, CA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Charlotte, NC to San Diego, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Charlotte, NC to San Diego, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Charlotte, NC to San Diego, CA.
Journey information
Overview: Bus from Charlotte, NC to San Diego, CA
Buses from Charlotte, NC to San Diego, CA run on average 24 times per day, taking around 49h 55m. Cheap bus tickets for this journey start at $177 (€140) if you book in advance.
The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 2076 miles (3342 km) distance in 60h 15m.
Distance 2076 miles (3342 km) |
Average bus duration 49h 55m |
Cheapest ticket price $177 (€140) |
Buses per day 24 |
Fastest bus 60h 15m |
First bus 00:55 |
Last bus 23:55 |
Bus providers: Greyhound from Charlotte, NC to San Diego, CAYou can travel by bus between Charlotte, NC to San Diego, CA with Greyhound for as low as $177 (€140). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Charlotte, NC to San Diego, CA
Find answers to the most common questions about traveling from Charlotte, NC to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Charlotte, NC to San Diego, CA
More options for your journey from Charlotte, NC to San Diego, CA
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