- Must visit
Royal Museums of Fine Arts of Belgium
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Cheapest price
$99
Average price
$151
Fastest journey
4 h 27 m
Average duration
4 h 34 m
Trains per day
33
Distance
354 km
The best way to find a cheap train ticket from Karlsruhe to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Brussels will cost around $151 if you buy it on the day, but the cheapest tickets can be found for only $99.
It's difficult to get from Karlsruhe to Brussels without transferring at least once.
ICE 76 · ICE 1014 · ICE 1022 · ICE 1112
ICE 1649 · ICE 318
ICE 102 · ICE 318
IC 60402 · ICE 18
IC 60402 · ICE 316
ICE 202 · ICE 692 · ICE 16
ICE 376 · ICE 614 · ICE 1112
ICE 202 · ICE 16
ICE 204 · ICE 316
ICE 108 · ICE 14Omio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a train which can get you there in 3h 36m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $26, and a train costs an average of $54.
Distance: 219 miles (354 km)
Most popular Train | Bus | Driving |
|---|---|---|
$141 Average price | $53 Average price Cheapest | $87 Average price (fuel + tolls) |
4h 6m Average total duration Fastest 3h 36m Onboard + 30m Additional time* | 7h 55m Average total duration 7h 25m Onboard + 30m Additional time* | 5h 30m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Brussels:
A bus is $89 (€72) less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $141 (€114).
Other travel options to Brussels take longer:
Bus takes on average 7h 25m.
You'll arrive about 1h 54m sooner (3h 36m by train vs 5h 30m by car). Tickets start at around $141 (€114) compared to roughly $87 (€71) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Karlsruhe to Brussels trains for today, Tuesday, June 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ECE 8 · ICE 314 | On time 8:37 AM Karlsruhe Hbf | 6h49 | 3:26 PM Brussels-North | 1 transfer | |
ICE 202 · ICE 692 · ICE 314 | Delayed 7:00 AM 8:59 AMKarlsruhe Hbf | 6h27 | 3:26 PM Brussels-North | 2 transfers | |
TGV 9561+ ICE 314 | Delayed 8:39 AM 9:54 AMKarlsruhe Hbf | 5h32 | 3:26 PM Brussels-North | 1 transfer | |
ICE 374 · ICE 314 | On time 9:59 AM Karlsruhe Hbf | 5h36 | 3:35 PM Brussels-Midi | 1 transfer | |
4472 · ICE 926 · ICE 14 | On time 10:06 AM Karlsruhe Hbf | 7h29 | 5:35 PM Brussels-Midi | 2 transfers | |
ICE 200 · ICE 14 | On time 10:59 AM Karlsruhe Hbf | 6h36 | 5:35 PM Brussels-Midi | 1 transfer | |
ICE 372 · ICE 610 · ICE 14 | On time 11:59 AM Karlsruhe Hbf | 5h36 | 5:35 PM Brussels-Midi | 2 transfers | |
| Wednesday, June 3 | |||||
S6 · 4550 · ICE 18 | On time 3:25 AM Karlsruhe Hbf | 6h10 | 9:35 AM Brussels-Midi | 2 transfers | |
S6 · 4550 · ICE 18 | On time 3:25 AM Karlsruhe Hbf | 6h01 | 9:26 AM Brussels-North | 2 transfers | |
S6 · ICE 712 · ICE 316 | On time 3:25 AM Karlsruhe Hbf | 8h10 | 11:35 AM Brussels-Midi | 2 transfers | |
S6 · ICE 712 · ICE 1112 | On time 3:25 AM Karlsruhe Hbf | 9h10 | 12:35 PM Brussels-Midi | 2 transfers | |
S9 · ICE 776 · ICE 1022 · ICE 1112 | On time 4:57 AM Karlsruhe Hbf | 7h29 | 12:26 PM Brussels-North | 3 transfers | |
S9 · ICE 776 · ICE 316 | On time 4:57 AM Karlsruhe Hbf | 6h29 | 11:26 AM Brussels-North | 2 transfers | |
ICE 378 · ICE 616 · ICE 316 | On time 5:59 AM Karlsruhe Hbf | 5h36 | 11:35 AM Brussels-Midi | 2 transfers | |
ICE 378 · ICE 616 · ICE 1112 | On time 5:59 AM Karlsruhe Hbf | 6h36 | 12:35 PM Brussels-Midi | 2 transfers | |
ICE 378 · ICE 1022 · ICE 1112 | On time 5:59 AM Karlsruhe Hbf | 6h36 | 12:35 PM Brussels-Midi | 2 transfers | |
ICE 378 · ICE 316 | On time 5:59 AM Karlsruhe Hbf | 5h27 | 11:26 AM Brussels-North | 1 transfer | |
ICE 76 · ICE 1014 · ICE 1022 · ICE 1112 | On time 6:37 AM Karlsruhe Hbf | 5h58 | 12:35 PM Brussels-Midi | 3 transfers | |
ICE 76 · ICE 316 | On time 6:37 AM Karlsruhe Hbf | 4h49 | 11:26 AM Brussels-North | 1 transfer | |
ICE 204 · ICE 316 | On time 6:59 AM Karlsruhe Hbf | 4h36 | 11:35 AM Brussels-Midi | 1 transfer | |
ICE 1049 · ICE 16 | On time 7:53 AM Karlsruhe Hbf | 5h42 | 1:35 PM Brussels-Midi | 1 transfer | |
ICE 376 · ICE 614 · ICE 16 | On time 7:59 AM Karlsruhe Hbf | 5h36 | 1:35 PM Brussels-Midi | 2 transfers | |
ICE 376 · ICE 16 | On time 7:59 AM Karlsruhe Hbf | 5h27 | 1:26 PM Brussels-North | 1 transfer | |
ICE 376 · ICE 614 · ICE 1112 | On time 7:59 AM Karlsruhe Hbf | 4h36 | 12:35 PM Brussels-Midi | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Karlsruhe to Brussels run on average 5 times per day, taking around 3h 36m. Cheap train tickets for this journey start at $54 (€44) but you can travel from only $26 (€21) by bus.
The earliest train runs at 00:20, the last at 22:01. The fastest train covers the 219 miles (354 km) distance in 4h 36m.
Distance 219 miles (354 km) |
Average train duration 3h 36m |
Cheapest ticket price $54 (€44) |
Trains per day 5 |
Fastest train 4h 36m |
First train 12:20 AM |
Last train 10:01 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 49 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
A major complex of art museums covering Flemish masters, Old Masters, and modern art. One of Brussels' essential cultural visits for its scale and national importance.
Dedicated to René Magritte, this museum holds the world's largest collection of his works. It is a standout stop for surrealism lovers and one of Brussels' most famous museums.
A contemporary art museum known for street art, digital culture, and youth-oriented exhibitions. It became especially popular with younger visitors and on social media.
A landscaped cultural hill linking the upper and lower city, known for its formal gardens and classic skyline view. It is one of Brussels' best walking and photography spots.
A beautiful 19th-century covered arcade with elegant glass roofing and historic atmosphere. It is one of the city's most photogenic and fashionable passages.
A grand urban park laid out around monumental buildings and the Cinquantenaire Arch. Ideal for a walk, photos, and combining with nearby museums.
Brussels’ classic pairing of mussels steamed with white wine, celery, and herbs, served with crisp fries. It is one of the city’s most iconic and widely loved meals.
A traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. It is a staple of local brasserie cuisine.
A comforting Brussels side dish of mashed potatoes mixed with seasonal vegetables such as carrots, leeks, or spinach, often served with sausage or meat.
Well-regarded Belgian restaurant serving regional classics, strong beer pairings, and seasonal ingredients in a cozy, old-Brussels dining room.
One of Brussels’ landmark fine-dining restaurants, celebrated for refined Belgian-influenced cuisine, polished service, and an elegant Art Nouveau setting.
Popular traditional restaurant near Sainte-Catherine known for generous Belgian comfort food, beer-based stews, and an unfussy, bustling atmosphere.
Moderate by Western European standards. Beer, waffles, and transit are reasonable; hotels and central dining cost more.
Service is usually included. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Round up taxi fares.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Karlsruhe to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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