- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Sep 01
$57
Average ticket price on Sep 01
$146
Fastest journey on Sep 01
4 h 36 m
Average journey duration on Sep 01
4 h 36 m
Trains on Sep 01
17
Distance
354 km
The best way to find a cheap train ticket from Karlsruhe to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Brussels will cost around $146 if you buy it on the day, but the cheapest tickets can be found for only $57.
It's difficult to get from Karlsruhe to Brussels without transferring at least once.
ICE 104 · ICE 10
S6 · 33600 · ICE 316
S6 · 4550 · ICE 18
ICE 278 · IC 1143 · ICE 10
ICE 376 · IC 1149 · ICE 16
ICE 104 · ICE 10
ICE 204 · ICE 316
ICE 202 · ICE 16
ICE 200 · ICE 314
ICE 108 · ICE 14Omio recommends booking the train as it is the most popular option from Karlsruhe to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $49 For those with little time, consider booking a train, which has an average total journey time of 4h 5m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $49, while a train costs an average of $120.
Distance: 219 miles (354 km)
Most popular Train | Bus | Driving |
|---|---|---|
$120 Average price | $49 Average price Cheapest | $88 Average price (fuel + tolls) |
4h 5m Average total duration Fastest 3h 35m Onboard + 30m Additional time* | 7h 13m Average total duration 6h 43m Onboard + 30m Additional time* | 5h 30m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Brussels:
A bus is $71 less than a train for this route with tickets for a train from Karlsruhe to Brussels costing on average $120.
Other travel options to Brussels take longer:
Bus takes on average 6h 43m.
You'll arrive about 1h 55m sooner (3h 35m by train vs 5h 30m by car). Tickets start at around $120 compared to roughly $88 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Karlsruhe to Brussels trains for tomorrow, Tuesday, September 1. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
S6 · 4550 · ICE 18 | On time 3:25 AM Karlsruhe | 6h10 | 9:35 AM Brussels-Midi | 2 transfers | |
S6 · 33600 · ICE 316 | On time 3:25 AM Karlsruhe | 8h10 | 11:35 AM Brussels-Midi | 2 transfers | |
ICE 204 · ICE 316 | On time 6:59 AM Karlsruhe | 4h36 | 11:35 AM Brussels-Midi | 1 transfer | |
ICE 376 · IC 1149 · ICE 16 | On time 7:59 AM Karlsruhe | 5h36 | 1:35 PM Brussels-Midi | 2 transfers | |
ICE 202 · ICE 16 | On time 8:59 AM Karlsruhe | 4h36 | 1:35 PM Brussels-Midi | 1 transfer | |
ICE 374 · IC 1147 · ICE 314 | On time 9:59 AM Karlsruhe | 5h36 | 3:35 PM Brussels-Midi | 2 transfers | |
ICE 200 · ICE 314 | On time 10:59 AM Karlsruhe | 4h36 | 3:35 PM Brussels-Midi | 1 transfer | |
ICE 372 · IC 1145 · ICE 14 | On time 11:59 AM Karlsruhe | 5h36 | 5:35 PM Brussels-Midi | 2 transfers | |
ICE 108 · ICE 14 | On time 12:59 PM Karlsruhe | 4h36 | 5:35 PM Brussels-Midi | 1 transfer | |
ICE 370 · ICE 2012 · 28526 · ICE 12 | On time 1:59 PM Karlsruhe | 5h36 | 7:35 PM Brussels-Midi | 3 transfers | |
ICE 106 · ICE 12 | On time 2:59 PM Karlsruhe | 4h36 | 7:35 PM Brussels-Midi | 1 transfer | |
ICE 278 · IC 1143 · ICE 10 | On time 3:59 PM Karlsruhe | 5h36 | 9:35 PM Brussels-Midi | 2 transfers | |
ICE 104 · ICE 10 | On time 4:59 PM Karlsruhe Hbf | 4h36 | 9:35 PM Brussels-Midi | 1 transfer | |
ICE 276 · ICE 514 · 26830 · 18970 | 5:59 PM Karlsruhe Hbf | 6h28 | 12:27 AM Brussels-Midi | 4 transfers | |
ICE 102 · 26832 · 18978 · IC 2827 | 6:59 PM Karlsruhe Hbf | 10h48 | 5:47 AM Brussels-Midi | 3 transfers | |
ICE 274 · ICE 512 · 26834 · 18978 | 7:59 PM Karlsruhe Hbf | 9h48 | 5:47 AM Brussels-Midi | 4 transfers | |
ICE 2 · ICE 910 · 26836 · 18982 | 8:37 PM Karlsruhe Hbf | 11h28 | 8:05 AM Brussels-Midi | 6 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Karlsruhe to Brussels run on average 5 times per day, taking around 3h 35m. Cheap train tickets for this journey start at $68 but you can travel from only $28 by bus.
The earliest train runs at 00:20, the last at 22:01. The fastest train covers the 219 miles (354 km) distance in 4h 36m.
Distance 219 miles (354 km) |
Average train duration 3h 35m |
Cheapest ticket price $68 |
Trains per day 5 |
Fastest train 4h 36m |
First train 12:20 AM |
Last train 10:01 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 21 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Karlsruhe to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Karlsruhe to Brussels trains use the Karlsruhe Hbf to Bruxelles-Midi station pair, with some services arriving at Bruxelles-Central. Use this guide to compare Karlsruhe and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Karlsruhe Hbf is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe Hbf has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Vinarte, Am Tiergarten, Panorama, Alter Brauhof
Wi-Fi is available at Karlsruhe Hbf. ATMs are available at Karlsruhe Hbf.
Ticket office support is available at Karlsruhe Hbf. Information desks are available at Karlsruhe Hbf.
Luggage storage is available at Karlsruhe Hbf. Lost and found is available at the station.
Available at Karlsruhe Hbf: Parking, Taxis, WC.
Available at Karlsruhe Hbf: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe Hbf.
Nearby hotels include Hotel Barbarossa, Hotel Avisa, Am Tiergarten, Aparthotel Aijana.
Karlsruhe-Durlach is 5 km from Karlsruhe city centre. Public transport options include:
Karlsruhe-Durlach has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Hubraum, Vogel Hausbräu Durlach, Asia Gourmet, Borsalino
Wi-Fi is available at Karlsruhe-Durlach. ATMs are available at Karlsruhe-Durlach.
Ticket office support is available at Karlsruhe-Durlach. Information desks are available at Karlsruhe-Durlach.
Luggage storage is available at Karlsruhe-Durlach. Lost and found is available at the station.
Available at Karlsruhe-Durlach: Parking, Taxis, WC.
Available at Karlsruhe-Durlach: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe-Durlach.
Nearby hotels include Hotel Große Linde, Zum Erwin, Der Blaue Reiter.
Karlsruhe West is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe West has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Beim Schupi, Rosenstüble 2.0, Saloniki, Rote Taube
Wi-Fi is available at Karlsruhe West. ATMs are available at Karlsruhe West.
Ticket office support is available at Karlsruhe West. Information desks are available at Karlsruhe West.
Luggage storage is available at Karlsruhe West. Lost and found is available at the station.
Available at Karlsruhe West: Parking, Taxis, WC.
Available at Karlsruhe West: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Karlsruhe West.
Nearby hotels include Beim Schupi.
Bruxelles-Midi has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Pullman Hotel Bar, Quick Gare du Midi, Subway, EXKi Zuid, Starbucks, Häagen-Dazs, Sbarro, The Coffee Club, The Belgian Chocolate House, PAUL, & many more
Wi-Fi is available for a fee. ATMs are available at Bruxelles-Midi.
Ticket office support is available at Bruxelles-Midi. Information desks are located in the main concourse and next to the international platforms.
Luggage storage is baggage storage facility is located across from the Thalys business lounge.
Available at Bruxelles-Midi: Parking, Taxis, WC.
Available at Bruxelles-Midi: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Bruxelles-Midi: Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Nearby hotels include Les Lofts De Styliste, Park Inn by Radisson Brussels Midi, Pullman Brussels Centre Midi.
Bruxelles-Central has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Starbucks, Brasserie 28 Brewery, Panos, Delitraiteur Eat & Go
Free Wi-Fi available in Starbucks. ATMs are aTM machine is downstairs from the main entrance on the right side.
The ticket office is open Mon - Sun: 06:15 - 22:00. Information desks are travel Center / information desk is located on the left side from the main entrance.
Luggage storage is luggage lockers are located on Level 0 near Platforms 1 and 2.
Available at Bruxelles-Central: Parking, Taxis, WC.
Available at Bruxelles-Central: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Bruxelles-Central: Station has a wide range of facilities for passengers with limited mobility: elevators and escalators to platforms, wheelchair lifts and mobile ramps, barrier-free toilets and accessible parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Nearby hotels include Hilton Brussels Grand Palace, Hotel NH Brussels Carrefour de l'Europe, Hôtel The Moon.
Brussels-Nord is 1 km from Brussels city centre. Public transport options include:
Brussels-Nord has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Chabrol Brasserie, Winok Café, Félix Wine Bar
Free. ATMs are available in the train station.
Ticket office support is available at Brussels-Nord. Information desks are located in the main hall.
Luggage storage is available at Brussels-Nord. Lost and found is available at the station.
Available at Brussels-Nord: Parking, Taxis, WC.
Available at Brussels-Nord: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Brussels-Nord: Elevators, ramps.
Nearby hotels include Hotel Progress, Hilton Brussels City, Hotel Siru.
Here are some other resources that might have the information you need