The cheapest and fastest trains from Karlsruhe to Milan
Cheapest price
$171
Average price
$172
Fastest journey
6 h 39 m
Average duration
8 h 32 m
Trains per day
4
Distance
398 km
The best way to find a cheap train ticket from Karlsruhe to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Milan will cost around $172 if you buy it on the day, but the cheapest tickets can be found for only $171.
Of the 4 trains that leave Karlsruhe for Milan on Thu, Mar 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Mar 05 the direct trains cover the 398 km distance in an average of 8 h 32 m but if you time it right, some trains will get you there in just 6 h 39 m .
On Thu, Mar 05 the slowest trains will take 10 h 49 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
ICE 275+
IR 26 2319 | 2319 · IC 2 869 | 869+
EuroCity 21
ICE 275+
IR 26 2319 | 2319 · IC 2 869 | 869+
EuroCity 23
ICE 275+
IR 26 2319 | 2319 · IC 2 869 | 869+
EuroCity 151
ECE 151
ECE 151
ICE 275+
IR 26 2319 | 2319 · IC 2 869 | 869+
EuroCity 151
ICE 275+
IR 26 2319 | 2319 · IC 2 869 | 869+
EuroCity 21
ICE 275+
IR 26 2319 | 2319 · IC 2 869 | 869+
EuroCity 23Travel Information
Compare train and bus for Karlsruhe to Milan
Omio recommends booking the train as it is the most popular option from Karlsruhe to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 6h 26m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $76.
Distance: 247 miles (398 km)
Compare train with
Most popular Train | Bus |
|---|---|
$176 Average price | $54 Average price Cheapest |
6h 56m Average total duration Fastest 6h 26m Onboard + 30m Additional time* | 11h 13m Average total duration 10h 43m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Karlsruhe to Milan train times
The table below shows live departures for Karlsruhe to Milan trains for today, Wednesday, March 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ECE 151 | On time 8:11 AM Karlsruhe Hbf | 6h39 | 2:50 PM Milan Centrale | 0 transfersDirect | |
| Thursday, March 5 | |||||
ICE 275+ IR 26 2319 | 2319 · IC 2 869 | 869+ EuroCity 21 | 7:01 AM Karlsruhe Hbf | 8h49 | 3:50 PM Milan Centrale | 3 transfers | |
ICE 275+ IR 26 2319 | 2319 · IC 2 869 | 869+ EuroCity 23 | 7:01 AM Karlsruhe Hbf | 10h49 | 5:50 PM Milan Centrale | 3 transfers | |
ICE 275+ IR 26 2319 | 2319 · IC 2 869 | 869+ EuroCity 151 | 7:01 AM Karlsruhe Hbf | 7h49 | 2:50 PM Milan Centrale | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Milan by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Why should you book Karlsruhe to Milan trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Trenitalia to find the best option for your trip from Karlsruhe to Milan.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Milan.
Why book with Omio over Trainline or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Trenitalia to find the best option for your trip from Karlsruhe to Milan.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Milan.
How far in advance should I book train tickets from Karlsruhe to Milan?
Journey information
Overview: Train from Karlsruhe to Milan
Trains from Karlsruhe to Milan run on average 2 times per day, taking around 6h 26m. Cheap train tickets for this journey start at $76 (€62) but you can travel from only $24 (€19) by bus.
There are 1 trains per day. The earliest train runs at 00:15, the last at 21:50. The fastest train covers the 247 miles (398 km) distance in 6h 39m.
Distance 247 miles (398 km) |
Average train duration 6h 26m |
Cheapest ticket price $76 (€62) |
Trains per day 2 |
Direct trains 1 |
Fastest train 6h 39m |
First train 00:15 |
Last train 21:50 |
Train companies: Deutsche Bahn, Trenitalia from Karlsruhe to Milan trainsDeutsche Bahn, Trenitalia trains will get you between Karlsruhe and Milan from $24 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Trenitalia
FAQs: Trains from Karlsruhe to Milan
Find answers to the most common questions about traveling from Karlsruhe to Milan by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Karlsruhe to Milan
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- Adler
- Denkfabrik
- Cafeteria
- Asia Imbiss
- Auerhahn
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Karlsruhe
More options for your journey from Karlsruhe to Milan
Here are some other resources that might have the information you need

