Travel Information
Compare bus and train for Karlsruhe to Florence
Omio recommends booking the train as it is the most popular option from Karlsruhe to Florence among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a train which can get you there in 7h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $43, and a train costs an average of $196.
Distance: 386 miles (622 km)
Compare train with
Most popular Train | Bus |
|---|---|
$318 Average price | $79 Average price Cheapest |
8h 24m Average total duration Fastest 7h 54m Onboard + 30m Additional time* | 13h 41m Average total duration 13h 11m Onboard + 30m Additional time* |
0.2 - 0.6kg CO2 emissions Lowest | 0.6 - 1.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Karlsruhe to Florence by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 04
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Why should you book Karlsruhe to Florence trains with Omio?
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of Deutsche Bahn to find the best option for your trip from Karlsruhe to Florence.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlsruhe to Florence.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Deutsche Bahn to find the best option for your trip from Karlsruhe to Florence.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlsruhe to Florence.
Journey information
Overview: Train from Karlsruhe to Florence
Trains from Karlsruhe to Florence run on average 1 times per day, taking around 7h 54m. Cheap train tickets for this journey start at $196 (€159) but you can travel from only $43 (€35) by bus.
The earliest train runs at 00:05, the last at 23:40. The fastest train covers the 386 miles (622 km) distance in 8h 24m.
Distance 386 miles (622 km) |
Average train duration 7h 54m |
Cheapest ticket price $196 (€159) |
Trains per day 1 |
Fastest train 8h 24m |
First train 00:05 |
Last train 23:40 |
Train companies: Trenitalia, Deutsche Bahn from Karlsruhe to Florence trainsTrenitalia, Deutsche Bahn trains will get you between Karlsruhe and Florence from $43 (€35). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Trains from Karlsruhe to Florence
Find answers to the most common questions about traveling from Karlsruhe to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Karlsruhe to Florence
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
Most popular train connections from Karlsruhe
More options for your journey from Karlsruhe to Florence
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