Travel Information
Compare bus for Karlsruhe to Florence
Omio recommends booking the bus as it is the most popular option from Karlsruhe to Florence among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €85 For those with little time, consider booking a bus, which has an average total journey time of 13h 54m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.6 - 1.6kg. Average ticket prices depend on the travel mode: a bus costs an average of €85, while a bus costs an average of €85.
Distance: 386 miles (622 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
€85 Average price Cheapest | €211 Average price (fuel + tolls) |
13h 54m Average total duration Fastest 13h 24m Onboard + 30m Additional time* | 9h 16m Average total duration (door-to-door) |
0.6 - 1.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Karlsruhe to Florence
Compare the available ways to get from Karlsruhe to Florence, with the key details around price, speed, convenience, and direct service.
Tickets start at around €85 compared to roughly €211 in fuel and tolls — a saving of about €126. The journey takes 13h 24m versus 9h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Karlsruhe to Florence
How to get from Karlsruhe to Florence by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Florence is by taking a bus because it’s the best combination of price and speed.

7:10 PM 14h15 Karlsruhe 9:25 AM Florence €51 1 One-way 0 transfers
Cheapest

7:10 PM 14h15 Karlsruhe 9:25 AM Florence €51 1 One-way 0 transfers
Fastest

7:10 PM 14h15 Karlsruhe 9:25 AM Florence €51 1 One-way 0 transfers
Other options

1:20 AM 17h40 Karlsruhe 7:00 PM Florence €65 1 One-way 0 transfers
6:10 PM 14h15 Karlsruhe 8:25 AM Florence €68 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Karlsruhe to Florence
Travel to Florence easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Florence.

- Around 13 buses per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Florence as scheduled services by bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Florence Santa Maria Novella.
- Buses mostly depart from Karlsruhe Hbf and arrive in Scandicci, Villa Costanza (Florence).
- Travel with FlixBus, Marino Autolinee, BlaBlaCar Bus to go to Florence by bus.
- 1 direct buses per day with FlixBus.
Travelling from Karlsruhe to Florence: related information
Here are some other resources that might have the information you need
