- Must visit
Uffizi Gallery
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.






Cheapest price
$139
Average price
$174
Fastest journey
16h 5m
Average duration
19h 45m
Buses per day
6
Distance
302 km
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Florence among Omio's users. If you are prioritising price take the bus with prices starting from $61. For those with little time consider booking a flight which can get you there in 2h 40m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.8kg. The ticket price range depends on the travel mode: a bus costs an average of $61, and a flight costs an average of $144.
Distance: 454 miles (732 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$352 Average price | $90 Average price Cheapest | $281 Average price (fuel + tolls) |
5h 40m Average total duration Fastest 2h 40m Onboard + 3h 0m Additional time* | 21h 20m Average total duration 20h 50m Onboard + 30m Additional time* | 10h 36m Average total duration (door-to-door) |
2.2 - 4.4kg CO2 emissions | 0.7 - 1.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Florence:
A bus is $262 (€216) less than a flight for this route with tickets for a flight from Frankfurt am Main to Florence costing on average $352 (€290).
Other travel options to Florence take longer:
Train takes on average 12h 8m.
Bus takes on average 20h 50m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Frankfurt am Main to Florence and enjoy the approximately 454 miles (732 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 00:05, the last at 23:40.
Distance 454 miles (732 km) |
Average train duration 12h 8m |
Trains per day 3 |
First train 12:05 AM |
Last train 11:40 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 6 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.
Houses Michelangelo’s David alongside major Renaissance sculptures. A must for first-time visitors interested in Florence’s artistic legacy.
Monastic museum with Fra Angelico frescoes and tranquil cells. Ideal for experiencing spiritual art in one of Florence’s most atmospheric spaces.
Florence’s monumental main square, framed by civic buildings and sculpture. A must for first impressions, history, and lively urban atmosphere.
The cathedral square is Florence’s ceremonial heart, surrounded by the Duomo, Baptistery, and bell tower. Essential for architecture lovers.
Riverside viewpoint with one of Florence’s classic panoramas. Best at sunset for sweeping views over the Arno, domes, and historic center.
Thick Florentine T-bone steak from Chianina beef, grilled rare over coals. It is the city's signature celebratory dish and a classic of Tuscan cuisine.
A rustic Tuscan bread soup with black cabbage, cannellini beans, vegetables, and olive oil. A beloved frugal dish rooted in Florentine home cooking.
A thick soup of bread, tomatoes, basil, garlic, and olive oil, served warm or at room temperature. It celebrates simple Tuscan ingredients and stale bread.
Three-Michelin-star fine dining by Enoteca Pinchiorri, known for refined Italian cuisine and an exceptional wine cellar. Elegant and formal.
Legendary casual stop for Lampredotto sandwiches and other tripe specialties. Simple, authentic street food experience in central Florence.
Historic steakhouse famed for Bistecca Alla Fiorentina and classic Tuscan dishes. Traditional, bustling atmosphere near Santa Croce.
Moderate for Italy: hotels in the center are pricier, but dining and transit are reasonable versus Rome or Venice.
Service is often included. Round up or leave €1-2 at cafés, 5-10% for great restaurant service, and round up taxi fares.
Official public transport app
Firenze Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Frankfurt am Main to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Florence trains use the Frankfurt (Main) Süd to station pair. Use this guide to compare Frankfurt am Main and Florence train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Frankfurt (Main) Süd is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) Süd has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Merals Imbiss, Bootshaus am Eisernen Steg, Freigut, Holbein's
Wi-Fi is available at Frankfurt (Main) Süd. ATMs are available at Frankfurt (Main) Süd.
Ticket office support is available at Frankfurt (Main) Süd. Information desks are available at Frankfurt (Main) Süd.
Luggage storage is available at Frankfurt (Main) Süd. Lost and found is available at the station.
Available at Frankfurt (Main) Süd: Parking, Taxis, WC.
Available at Frankfurt (Main) Süd: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) Süd.
Nearby hotels include Hotel am Berg, Leonardo Royal Hotel Frankfurt, Hotel Ritter, Lindner Main Plaza.
Frankfurt (Main) West is 3 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) West has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Immer Satt, Café Crumble, Café Albatros, Cafe Extrablatt
Wi-Fi is available at Frankfurt (Main) West. ATMs are available at Frankfurt (Main) West.
Ticket office support is available at Frankfurt (Main) West. Information desks are available at Frankfurt (Main) West.
Luggage storage is available at Frankfurt (Main) West. Lost and found is available at the station.
Available at Frankfurt (Main) West: Parking, Taxis, WC.
Available at Frankfurt (Main) West: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) West.
Nearby hotels include Frankfurt Marriott Hotel, Imperial, Sophien Hotel, Hotel Isha.
Here are some other resources that might have the information you need