- Must visit
Uffizi Galleries
Florence’s premier art museum, famed for Botticelli, Leonardo, Michelangelo, and Raphael. One of Italy’s essential museum visits and often requires advance booking in busy seasons.
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Florence among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 2h 40m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.8kg. The ticket price range depends on the travel mode: a bus costs an average of $62, and a flight costs an average of $148.
Distance: 454 miles (732 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$360 Average price | $92 Average price Cheapest | $288 Average price (fuel + tolls) |
5h 40m Average total duration Fastest 2h 40m Onboard + 3h 0m Additional time* | 21h 20m Average total duration 20h 50m Onboard + 30m Additional time* | 10h 36m Average total duration (door-to-door) |
2.2 - 4.4kg CO2 emissions | 0.7 - 1.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Florence:
A bus is $269 (€216) less than a flight for this route with tickets for a flight from Frankfurt am Main to Florence costing on average $360 (€290).
Other travel options to Florence take longer:
Train takes on average 12h 8m.
Bus takes on average 20h 50m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Frankfurt am Main to Florence and enjoy the approximately 454 miles (732 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 00:05, the last at 23:40.
Distance 454 miles (732 km) |
Average train duration 12h 8m |
Trains per day 3 |
First train 12:05 AM |
Last train 11:40 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 6 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
Florence’s premier art museum, famed for Botticelli, Leonardo, Michelangelo, and Raphael. One of Italy’s essential museum visits and often requires advance booking in busy seasons.
Best known for Michelangelo’s David, this compact but world-famous museum also holds important Florentine paintings and sculpture. Timed entry is commonly advisable.
Outstanding museum for original sculptures and treasures from Florence Cathedral, including works by Donatello, Ghiberti, and Michelangelo. A superb companion to the Duomo complex.
The monumental heart of Florence, surrounded by the cathedral, baptistery, and bell tower. Essential for first-time visitors and iconic city views.
Historic civic square lined with statues and anchored by Palazzo Vecchio. A lively open-air showcase of Florence’s political and artistic heritage.
The city’s most famous viewpoint, especially popular at sunset for sweeping panoramas over Florence. A social-media favorite and classic photo stop.
A Thick-Cut T-Bone Steak From Chianina Beef, Charcoal-Grilled Rare. It Is Florence’s Signature Dish And A Classic Of Tuscan Cooking.
A Hearty Tuscan Soup Of Bread, Cannellini Beans, Kale, And Vegetables, Traditionally Reboiled The Next Day For Deeper Flavor.
A Rustic Tomato And Bread Soup With Garlic, Olive Oil, And Basil. It Is A Beloved Florentine Comfort Dish.
A Refined Michelin-Starred Restaurant Offering Creative Tuscan Cuisine In An Elegant Contemporary Setting.
An Old-Style Florentine Institution Known For Its Butter Chicken, Artichoke Omelette, And Traditional Tuscan Atmosphere.
Historic, Bustling Trattoria Near Mercato Centrale, Famous For Florentine Classics Such As Bistecca Alla Fiorentina And Ribollita.
Moderate for Italy: museums and central hotels cost more, while casual dining and local transport stay reasonable.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave 5-10% for very good service. Small change is fine in cafes; round up taxi fares.
Official public transport app
Florence Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Frankfurt am Main to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

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