- Must visit
Uffizi Galleries
Florence’s premier art museum, famed for Botticelli, Leonardo, Michelangelo, and Raphael. Timed-entry booking is strongly recommended due to very high demand.
Omio recommends booking the flight as it is the most popular option from Brussels to Florence among Omio's users. If you are prioritising price take the flight with prices starting from $24. For those with little time consider booking a flight which can get you there in 2h 19m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.4kg. The ticket price range depends on the travel mode: a flight costs an average of $24, and a train costs an average of $481.
Distance: 585 miles (943 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$481 Average price | $122 Average price Cheapest | $134 Average price | $350 Average price (fuel + tolls) |
25h 5m Average total duration 24h 35m Onboard + 30m Additional time* | 5h 19m Average total duration Fastest 2h 19m Onboard + 3h 0m Additional time* | 22h 46m Average total duration 22h 16m Onboard + 30m Additional time* | 14h 16m Average total duration (door-to-door) |
- CO2 emissions | 2.8 - 5.7kg CO2 emissions | 0.9 - 2.4kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Florence:
A flight is $12 (€10) less than a bus for this route with tickets for a bus from Brussels to Florence costing on average $134 (€108).
A flight is $359 (€290) less than a train for this route with tickets for a train from Brussels to Florence costing on average $481 (€388).
Other travel options to Florence take longer:
Bus takes on average 22h 16m.
Train takes on average 24h 35m.
Tickets start at around $481 (€388) compared to roughly $350 (€282) in fuel and tolls — a saving of about $-131.60 (€-106.13). The journey takes 24h 35m versus 14h 16m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Brussels to Florence run on average 1 times per day, taking around 24h 35m. Cheap train tickets for this journey start at $481 (€388) but you can travel from only $24 (€19) by flight.
The earliest train runs at 00:40, the last at 19:30. The fastest train covers the 585 miles (943 km) distance in 24h 35m.
Distance 585 miles (943 km) |
Average train duration 24h 35m |
Cheapest ticket price $481 (€388) |
Trains per day 1 |
Fastest train 24h 35m |
First train 12:40 AM |
Last train 7:30 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 77 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
Florence’s premier art museum, famed for Botticelli, Leonardo, Michelangelo, and Raphael. Timed-entry booking is strongly recommended due to very high demand.
Best known for Michelangelo’s David, plus important Florentine paintings and sculpture. Advance booking is strongly recommended.
A vast former Medici palace housing major museums and royal apartments. Worth visiting for both art collections and palace interiors.
The ceremonial heart of Florence, framed by the cathedral, baptistery, and bell tower. Essential for first-time visitors.
Florence’s great civic square, packed with sculpture, historic atmosphere, and immediate access to key landmarks.
The city’s most famous viewpoint, especially popular at sunset for panoramic photos over Florence’s skyline.
Florence’s iconic thick-cut T-bone steak from Chianina beef, grilled rare and simply seasoned. It is one of the city’s most famous traditional dishes.
A hearty Tuscan soup of bread, cannellini beans, and winter vegetables, especially black cabbage. It is a classic peasant dish strongly associated with Florence and Tuscany.
A comforting tomato and bread soup made with stale bread, garlic, olive oil, and basil. It is a beloved Florentine-Tuscan staple.
Florence’s landmark fine-dining destination, renowned for haute cuisine, exceptional wine service, and one of Italy’s most prestigious cellars.
Long-established traditional restaurant known for its butter chicken, artichoke omelette, and intimate old-Florence atmosphere.
Historic, no-frills Florentine trattoria near Mercato Centrale, famous for bistecca alla Fiorentina, ribollita, and other classic Tuscan dishes.
Moderate for Italy: museums and central hotels cost more, while casual dining and local transport stay reasonable.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave 5-10% for very good service. Small change is fine in cafes; round up taxi fares.
Official public transport app
Florence Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Brussels to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

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