St. Louis, MO to Gainesville, FL bus with Greyhound

Tue, Sep 15
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2,000+ travel companies
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Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from St. Louis, MO to Gainesville, FL

Showing times, prices and bookable tickets for Sep 15

Cheapest price on Sep 15

$168

Average ticket price on Sep 15

$168

Fastest journey on Sep 15

18 h 30 m

Average journey duration on Sep 15

18 h 30 m

Buses on Sep 15

1

Distance

1232 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to Gainesville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to Gainesville, FL will cost around $168 if you buy it on the day, but the cheapest tickets can be found for only $168.

Fast buses

It's difficult to get from St. Louis, MO to Gainesville, FL without transferring at least once.

  • Flixbus USA
    11:30 PM18h30
    St. Louis, MO
    6:00 PMGainesville, FL
    $1681One-way
    1 transfer

Travel Information

Compare bus and train for St. Louis, MO to Gainesville, FL

Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Gainesville, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $126 For those with little time, consider booking a bus, which has an average total journey time of 18h 59m. Average ticket prices depend on the travel mode: a bus costs an average of $126, while a bus costs an average of $126.

Distance: 765 miles (1232 km)

Compare bus with

Most popular
Bus
Train
Driving

$126

Average price

Cheapest

$182

Average price

(fuel + tolls)

18h 59m

Average total duration

Fastest

18h 29m

Onboard

+

30m

Additional time*

13h 4m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from St. Louis, MO to Gainesville, FL is a bus with an average price of $126.
The fastest way to travel from St. Louis, MO to Gainesville, FL is by bus with an average journey time of 18h 29m.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and Gainesville, FL including taking a bus and train.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Gainesville, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $126 compared to roughly $182 in fuel and tolls — a saving of about $57. The journey takes 18h 29m versus 13h 4m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

St. Louis, MO to Gainesville, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:00AM
Arrival Time
03:40AM
Duration
25h40
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$86
Operator
Greyhound
Departure Time
09:00AM
Arrival Time
05:15AM
Duration
19h15
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$86
Operator
Greyhound
Departure Time
01:45PM
Arrival Time
02:25PM
Duration
23h40
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$86
Operator
Greyhound
Departure Time
04:00PM
Arrival Time
01:15PM
Duration
20h15
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$86
Operator
Flixbus USA
Departure Time
11:30PM
Arrival Time
06:00PM
Duration
18h30
Departure days
Tue, Wed, Thu
Cheapest price
$168
Operator
Greyhound
Departure Time
11:45PM
Arrival Time
12:30AM
Duration
23h45
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$86
Operator
FlixBus
Departure Time
11:45PM
Arrival Time
06:00PM
Duration
17h15
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$85

Live departures

St. Louis, MO to Gainesville, FL bus times

The table below shows live departures for St. Louis, MO to Gainesville, FL buses for today, Monday, September 14. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound+FlixBusFlixBus9:00 AM St. Louis, S 15th St (Civic center)
18h20
4:20 AM Gainesville, Rosa Parks Transfer station1 transfer
Greyhound · · +FlixBusFlixBus1:45 PM St. Louis, S 15th St (Civic center)
23h40
2:25 PM Gainesville, Rosa Parks Transfer station3 transfers
FlixBusFlixBus+Greyhound · 4:00 PM St. Louis, S 15th St (Civic center)
20h15
1:15 PM Gainesville, NW 23rd St (North Walmart Supercenter), FL2 transfers
FlixBusFlixBus · FlixBus11:45 PM St. Louis, S 15th St (Civic center)
17h15
6:00 PM Gainesville, Rosa Parks Transfer station1 transfer
FlixBusFlixBus+Greyhound · 11:45 PM St. Louis, S 15th St (Civic center)
23h45
12:30 AM Gainesville, NW 23rd St (North Walmart Supercenter), FL2 transfers

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to Gainesville, FL by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Sep 15
Wed
Sep 16
Thu
Sep 17
Fri
Sep 18
Sat
Sep 19
Sun
Sep 20
Mon
Sep 21

Why should you book St. Louis, MO to Gainesville, FL buses with Omio?

Greyhound as well as FlixBus offer buses services from St. Louis, MO to Gainesville, FL.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Gainesville, FL.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Gainesville, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and train to ensure you get the best deal for traveling from St. Louis, MO to Gainesville, FL.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Gainesville, FL.
  • Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from St. Louis, MO to Gainesville, FL.

Journey information

Overview: Bus from St. Louis, MO to Gainesville, FL

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to Gainesville, FL run on average 6 times per day, taking around 18h 29m. Cheap bus tickets for this journey start at $95 if you book in advance.

The earliest bus runs at 01:10, the last at 22:40. The fastest bus covers the 765 miles (1232 km) distance in 16h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
765 miles (1232 km)
Average bus duration
18h 29m
Cheapest ticket price
$95
Buses per day
6
Fastest bus
16h 25m
First bus
1:10 AM
Last bus
10:40 PM
Cheapest Month
Mar
Cheapest Day
Sun
High Season
Jul - Sep
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from St. Louis, MO to Gainesville, FLYou can travel by bus between St. Louis, MO to Gainesville, FL with Greyhound, FlixBus for as low as $95. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 25m
Cheapest FlixBus Price
$96
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
17h 10m
Cheapest Greyhound Price
$95
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from St. Louis, MO to Gainesville, FL

Find answers to the most common questions about traveling from St. Louis, MO to Gainesville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Gainesville, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to Gainesville, FL can start from as little as $95 when you book in advance. The average bus ticket price for St. Louis, MO to Gainesville, FL is $126 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Gainesville, FL is 16h 25m to travel the 765 miles (1232 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Gainesville, FL leaves at 1:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Gainesville, FL leaves at 10:40 PM.
There are 6 buses a day from St. Louis, MO to Gainesville, FL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Gainesville, FL, you can count on Greyhound, FlixBus for the best way to get you to Gainesville, FL. You can also check all possible bus companies who offer a service between St. Louis, MO and Gainesville, FL and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport . When arriving in Gainesville, FL , you can end your journey in bus stations like Gainesville, Rosa Parks Transfer station, Gainesville, NW 23rd St (North Walmart Supercenter), FL .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Gainesville, Rosa Parks Transfer station, located 0 away from the city centre.
A trip to Gainesville, FL from St. Louis, MO is worth doing but not as a day trip with a journey time of 16h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Gainesville, FL is March.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and Gainesville, FL including taking a bus and train.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Gainesville, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Gainesville, FL for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Gainesville, FL are:
  • Florida Museum of Natural History, featuring extensive exhibits on Florida's flora, fauna, and cultural heritage
  • Kanapaha Botanical Gardens, a 62-acre garden showcasing diverse plant collections and scenic landscapes
  • Devil's Millhopper Geological State Park, a unique geological formation with a large sinkhole and nature trails
  • Paynes Prairie Preserve State Park, offering wildlife viewing, hiking, and panoramic views of the prairie ecosystem
  • Samuel P. Harn Museum of Art, housing a diverse collection of artworks from around the world.
The best things to do in Gainesville, FL include:
  • Explore the vibrant local art scene at the Gainesville Artwalk, featuring galleries and live performances
  • Visit the Santa Fe College Teaching Zoo, home to a variety of animal species and educational programs
  • Enjoy a day of outdoor activities at Lake Wauburg, offering boating, picnicking, and climbing walls
  • Discover the historic Haile Homestead, known for its "Talking Walls" filled with writings from the 19th century
  • Attend a performance at the Hippodrome Theatre, showcasing plays, films, and special events.
Whether you can cancel your bus ticket from St. Louis, MO to Gainesville, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Gainesville, FL.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Gainesville, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Gainesville, FL:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Gainesville, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Gainesville, FL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Gainesville, FL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Gainesville, FL with the following bus company: Greyhound, FlixBus.
Since neither St. Louis, MO nor Gainesville, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Gainesville, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Gainesville, FL, travelers should be cautious of petty theft, especially in crowded areas like downtown and near the University of Florida campus. Common scams include overcharging by unofficial taxi or ride-share drivers and ticket scams for local events. It's important to use authorized transportation services and stay in well-lit, populated areas at night to enhance personal safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from St. Louis, MO to Gainesville, FL

Most St. Louis, MO to Gainesville, FL buses use the St. Louis, S 15th St (Civic center) to Gainesville, Rosa Parks Transfer station station pair, with some services arriving at Gainesville, NW 23rd St (North Walmart Supercenter). Use this guide to compare St. Louis, MO and Gainesville, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in St. Louis
Arrival bus stations in Gainesville

Which St. Louis, MO station do buses to Gainesville, FL leave from?

Buses from St. Louis, MO to Gainesville, FL leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre

TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min

St. Louis, S 15th St (Civic center) bus station facilities and services

St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).

Tickets and information

Ticket office support is available at St. Louis, S 15th St (Civic center).

Parking, taxis and toilets

Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.

St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to St. Louis, Lambert International Airport from St. Louis city centre

St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:

TrainMlr · 31m · $4 · every ~7 min
Bus4 · 1h 3m · $31 · every ~4 min

St. Louis, Lambert International Airport bus station facilities and services

St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Multiple dining options available in terminals.

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.

Tickets and information

Ticket office support is available at St. Louis, Lambert International Airport.

Parking, taxis and toilets

Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.

More options for your journey from St. Louis, MO to Gainesville, FL

Here are some other resources that might have the information you need

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