- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
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Travel Information
Compare bus and flight for Gainesville, FL to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Gainesville, FL to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €124 For those with little time, consider booking a bus, which has an average total journey time of 19h 48m. Average ticket prices depend on the travel mode: a bus costs an average of €124, while a bus costs an average of €124.
Distance: 765 miles (1232 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
€124 Average price Cheapest | €148 Average price (fuel + tolls) | |
19h 48m Average total duration Fastest 19h 18m Onboard + 30m Additional time* | 13h 1m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Gainesville, FL to St. Louis, MO is a bus with an average price of €124.
The fastest way to travel from Gainesville, FL to St. Louis, MO is by bus with an average journey time of 19h 18m.
It's helpful to compare your options as there are 2 ways to travel between Gainesville, FL and St. Louis, MO including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Gainesville, FL to St. Louis, MO among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around €124 compared to roughly €148 in fuel and tolls — a saving of about €24. The journey takes 19h 18m versus 13h 1m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Gainesville, FL to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:10AM | Arrival Time 09:30PM | Duration 21h20 | Departure days Mon, Thu, Fri | Cheapest price €71 |
Operator Greyhound | Departure Time 08:00AM | Arrival Time 03:10PM | Duration 32h10 | Departure days Mon | Cheapest price €77 |
Operator Greyhound | Departure Time 08:20AM | Arrival Time 09:20AM | Duration 26h00 | Departure days Mon, Thu, Fri | Cheapest price €72 |
Operator FlixBus | Departure Time 11:30AM | Arrival Time 09:20AM | Duration 22h50 | Departure days Thu | Cheapest price €70 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 03:55PM | Duration 27h25 | Departure days Mon, Thu, Fri | Cheapest price €70 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 02:15PM | Duration 22h00 | Departure days Mon | Cheapest price €75 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 09:20AM | Duration 17h05 | Departure days Fri | Cheapest price €79 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 03:55PM | Duration 22h50 | Departure days Mon, Thu, Fri | Cheapest price €70 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 09:20AM | Duration 37h00 | Departure days Thu | Cheapest price €75 |
Live departures
Gainesville, FL to St. Louis, MO bus times
The table below shows live departures for Gainesville, FL to St. Louis, MO buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 FlixBus+ | 1:10 AM Gainesville, Rosa Parks Transfer station | 21h20 | 9:30 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| · +FlixBus | 8:20 AM Gainesville, NW 23rd St (North Walmart Supercenter), FL | 26h00 | 9:20 AM St. Louis, S 15th St (Civic center) | 2 transfers | |
| +FlixBus+ · | 1:30 PM Gainesville, NW 23rd St (North Walmart Supercenter), FL | 27h25 | 3:55 PM St. Louis, S 15th St (Civic center) | 3 transfers | |
| FlixBus · FlixBus | 5:15 PM Gainesville, Rosa Parks Transfer station | 17h05 | 9:20 AM St. Louis, S 15th St (Civic center) | 1 transfer | |
| FlixBus · FlixBus+ · | 6:05 PM Gainesville, Rosa Parks Transfer station | 22h50 | 3:55 PM St. Louis, S 15th St (Civic center) | 3 transfers |
Find all the dates and times for this journey
Why should you book Gainesville, FL to St. Louis, MO buses with Omio?
Greyhound operates all buses services from Gainesville, FL to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Gainesville, FL to St. Louis, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Gainesville, FL to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Gainesville, FL to St. Louis, MO.
Journey information
Overview: Bus from Gainesville, FL to St. Louis, MO
USAUSA
Buses from Gainesville, FL to St. Louis, MO run on average 5 times per day, taking around 19h 18m. Cheap bus tickets for this journey start at €81 if you book in advance.
The earliest bus runs at 01:00, the last at 23:30. The fastest bus covers the 765 miles (1232 km) distance in 16h 31m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 765 miles (1232 km) |
Average bus duration 19h 18m |
Cheapest ticket price €81 |
Buses per day 5 |
Fastest bus 16h 31m |
First bus 1:00 AM |
Last bus 11:30 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Apr - Jun |
Best time to book 56 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound from Gainesville, FL to St. Louis, MOYou can travel by bus between Gainesville, FL to St. Louis, MO with FlixBus, Greyhound for as low as €81. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 31m
Cheapest FlixBus Price
€82
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
17h 35m
Cheapest Greyhound Price
€81
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Gainesville, FL to St. Louis, MO
Find answers to the most common questions about traveling from Gainesville, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Gainesville, FL to St. Louis, MO can start from as little as €81 when you book in advance. The average bus ticket price for Gainesville, FL to St. Louis, MO is €124 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Gainesville, FL to St. Louis, MO is 16h 31m to travel the 765 miles (1232 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Gainesville, FL to St. Louis, MO leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Gainesville, FL to St. Louis, MO leaves at 11:30 PM.
There are 5 buses a day from Gainesville, FL to St. Louis, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Gainesville, FL to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Gainesville, FL and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
When departing from Gainesville, FL , you have various bus station options to start your journey from including Gainesville, Rosa Parks Transfer station, Gainesville, NW 23rd St (North Walmart Supercenter), FL . When arriving in St. Louis, MO , you can end your journey in bus stations like St. Louis, S 15th St (Civic center), St. Louis, Lambert International Airport .Passengers board the bus most frequently from Gainesville, Rosa Parks Transfer station, which is located around away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
A trip to St. Louis, MO from Gainesville, FL is worth doing but not as a day trip with a journey time of 16h 31m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Gainesville, FL to St. Louis, MO is June.
It's helpful to compare your options as there are 2 ways to travel between Gainesville, FL and St. Louis, MO including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Gainesville, FL to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Gainesville, FL to St. Louis, MO for bus company Greyhound.
Whether you can cancel your bus ticket from Gainesville, FL to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Gainesville, FL to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Gainesville, FL to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Gainesville, FL to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Gainesville, FL to St. Louis, MO.
You can reserve your seat on the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound.
Since neither Gainesville, FL nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Gainesville, FL to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Gainesville, FL to St. Louis, MO
Most Gainesville, FL to St. Louis, MO buses use the Gainesville, Rosa Parks Transfer station to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Gainesville, FL and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Gainesville
Arrival bus stations in St. Louis
Which Gainesville, FL station do buses to St. Louis, MO leave from?
Buses from Gainesville, FL to St. Louis, MO leave from Gainesville, Rosa Parks Transfer station. The station is 0 miles (1 km) from Gainesville, FL city centre at Rosa Parks Transfer station, 700 SE 3rd St, Gainesville, FL 32601, USA.
Gainesville, Rosa Parks Transfer stationRosa Parks Transfer station, 700 SE 3rd St, Gainesville, FL 32601, USA
City-centre transport
Getting to Gainesville, Rosa Parks Transfer station from Gainesville city centre
Bus15, 6, 5, 46, 10, 1, 25 · 2m · every ~15 min
Gainesville, Rosa Parks Transfer station bus station facilities and services
Gainesville, Rosa Parks Transfer station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi is available at the station. ATMs are available at Gainesville, Rosa Parks Transfer station.
Tickets and information
Ticket office support is available at Gainesville, Rosa Parks Transfer station.
Parking, taxis and toilets
Available at Gainesville, Rosa Parks Transfer station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Gainesville, Rosa Parks Transfer station: The station is wheelchair accessible.
Gainesville, NW 23rd St (North Walmart Supercenter)5700 NW 23rd St, Gainesville, FL 32653, USA
City-centre transport
Getting to Gainesville, NW 23rd St (North Walmart Supercenter) from Gainesville city centre
Gainesville, NW 23rd St (North Walmart Supercenter) is 7 km from Gainesville city centre. Public transport options include:
Bus6 · 23m · every ~1 min
6 · 25m · every ~1 min
6 · 26m · every ~1 min
8 · 31m · every ~2 min
Gainesville, NW 23rd St (North Walmart Supercenter) bus station facilities and services
Gainesville, NW 23rd St (North Walmart Supercenter) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Gainesville, NW 23rd St (North Walmart Supercenter). ATMs are available at Gainesville, NW 23rd St (North Walmart Supercenter).
Tickets and information
Ticket office support is available at Gainesville, NW 23rd St (North Walmart Supercenter).
Parking, taxis and toilets
Available at Gainesville, NW 23rd St (North Walmart Supercenter): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Gainesville, NW 23rd St (North Walmart Supercenter): Bus stop has basic accessibility features.
Which St. Louis, MO station do buses from Gainesville, FL arrive at?
Buses from Gainesville, FL to St. Louis, MO most often arrive at St. Louis, S 15th St (Civic center). Some services arrive at St. Louis, Lambert International Airport, so check your ticket before travel to confirm your St. Louis, MO arrival station.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · €3 · every ~14 min
Bus19, 32, 40 · 8m · €1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis, Lambert International AirportSt. Louis Lambert International Airport (STL), 10701 Lambert International Blvd, St. Louis, MO 63145, USA
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
St. Louis, Lambert International Airport is 19 km from St. Louis city centre. Public transport options include:
TrainMlr · 31m · €3 · every ~7 min
Bus4 · 1h 3m · €25 · every ~4 min
St. Louis, Lambert International Airport bus station facilities and services
St. Louis, Lambert International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options available in terminals.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are aTMs available in terminal areas.
Tickets and information
Ticket office support is available at St. Louis, Lambert International Airport.
Parking, taxis and toilets
Available at St. Louis, Lambert International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, Lambert International Airport: Wheelchair accessible facilities available.
Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Gainesville, FL
Most popular bus connections to St. Louis, MO
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