- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
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Why should you book Gainesville, FL to St. Louis, MO buses with Omio?
Greyhound operates all buses services from Gainesville, FL to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Gainesville, FL to St. Louis, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Gainesville, FL to St. Louis, MO
USAUSA
Take a bus from Gainesville, FL to St. Louis, MO and enjoy the approximately 765 miles (1232 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 01:00, the last at 23:30.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 765 miles (1232 km) |
Average bus duration 16h 5m |
Buses per day 9 |
First bus 1:00 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jul - Sep |
Best time to book 56 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Gainesville, FL to St. Louis, MOYou can travel by bus between Gainesville, FL to St. Louis, MO with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis
Things to do in St. Louis
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
- Must visit
City Museum
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
- Recommended
Missouri History Museum
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
- Must visit
Forest Park
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
- Must visit
Gateway Arch National Park Grounds
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
- Recommended
The Delmar Loop
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
- Vegetarian
St. Louis-Style Pizza
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Toasted Ravioli
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
- Vegetarian
Gooey Butter Cake
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
Charlie Gitto's On The Hill
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
Ted Drewes Frozen Custard
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
Sidney Street Cafe
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
United States Dollar
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Average meal costs
- Budget
- USD 10-18 for fast food or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 70+ per person before drinks and tip.
- Coffee
- USD 3-6 for regular coffee or a latte.
Tipping culture
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from Gainesville, FL to St. Louis, MO
Find answers to the most common questions about traveling from Gainesville, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
The earliest bus from Gainesville, FL to St. Louis, MO leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Gainesville, FL to St. Louis, MO leaves at 11:30 PM.
There are 9 buses a day from Gainesville, FL to St. Louis, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Gainesville, FL to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Gainesville, FL and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
The cheapest month for a bus from Gainesville, FL to St. Louis, MO is July.
Yes, you can take a between Gainesville, FL and St. Louis, MO.
Yes, the following accessibility options are available when taking the bus from Gainesville, FL to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Gainesville, FL to St. Louis, MO for bus company Greyhound.
Whether you can cancel your bus ticket from Gainesville, FL to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Gainesville, FL to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Gainesville, FL to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Gainesville, FL to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Gainesville, FL to St. Louis, MO.
You can reserve your seat on the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound.
Since neither Gainesville, FL nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Gainesville, FL to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Gainesville, FL to St. Louis, MO
Gainesville
St. Louis
The major bus station for departures in Gainesville is Gainesville, Rosa Parks Transfer station. Find all the information you need to know about services, amenities and connections at Gainesville, Rosa Parks Transfer station for your trip from Gainesville to St. Louis.
Gainesville, Rosa Parks Transfer station
information
Gainesville, NW 23rd St (North Walmart Supercenter)
information
The major bus station for arrivals in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip to St. Louis from Gainesville.
St. Louis, S 15th St (Civic center)
information
Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Gainesville, FL
Most popular bus connections to St. Louis, MO
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