- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
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Gainesville, FL to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:10AM | Arrival Time 09:20PM | Duration 21h10 | Departure days Sat | Cheapest price €88 |
Operator Greyhound | Departure Time 08:20AM | Arrival Time 09:20AM | Duration 26h00 | Departure days Sat | Cheapest price €89 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 03:55PM | Duration 27h25 | Departure days Sat | Cheapest price €100 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 09:20AM | Duration 17h05 | Departure days Sat | Cheapest price €92 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 03:55PM | Duration 22h50 | Departure days Sat | Cheapest price €100 |
Why should you book Gainesville, FL to St. Louis, MO buses with Omio?
Greyhound operates all buses services from Gainesville, FL to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Gainesville, FL to St. Louis, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Bus providers: Greyhound from Gainesville, FL to St. Louis, MOYou can travel by bus between Gainesville, FL to St. Louis, MO with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Gainesville, FL to St. Louis, MO
Find answers to the most common questions about traveling from Gainesville, FL to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
The earliest bus from Gainesville, FL to St. Louis, MO leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Gainesville, FL to St. Louis, MO leaves at 11:30 PM.
There are 9 buses a day from Gainesville, FL to St. Louis, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Gainesville, FL to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Gainesville, FL and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
Yes, you can take a between Gainesville, FL and St. Louis, MO.
Yes, the following accessibility options are available when taking the bus from Gainesville, FL to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Gainesville, FL to St. Louis, MO for bus company Greyhound.
Whether you can cancel your bus ticket from Gainesville, FL to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Gainesville, FL to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Gainesville, FL to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Gainesville, FL to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Gainesville, FL to St. Louis, MO.
You can reserve your seat on the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Gainesville, FL to St. Louis, MO with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Gainesville, FL to St. Louis, MO
Most Gainesville, FL to St. Louis, MO buses use the Gainesville, Rosa Parks Transfer station to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Gainesville, FL and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Gainesville
Arrival bus stations in St. Louis
Gainesville, Rosa Parks Transfer station
City-centre transport
Getting to Gainesville, Rosa Parks Transfer station from Gainesville city centre
Bus15, 6, 5, 46, 10, 1, 25 · 2m · every ~15 min
Gainesville, NW 23rd St (North Walmart Supercenter)
City-centre transport
Getting to Gainesville, NW 23rd St (North Walmart Supercenter) from Gainesville city centre
Bus6 · 23m · every ~1 min
6 · 25m · every ~1 min
6 · 26m · every ~1 min
8 · 31m · every ~2 min
St. Louis, S 15th St (Civic center)
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · €3 · every ~14 min
Bus19, 32, 40 · 8m · €1 · every ~9 min
St. Louis, Lambert International Airport
City-centre transport
Getting to St. Louis, Lambert International Airport from St. Louis city centre
TrainMlr · 31m · €3 · every ~7 min
Bus4 · 1h 3m · €25 · every ~4 min
Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Gainesville, FL
Most popular bus connections to St. Louis, MO
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