- Must visit
Florida Museum of Natural History
Natural history museum with Florida fossils, butterfly exhibits, and family-friendly science displays on the University of Florida campus.
Cheapest price on Oct 31
$290
Average ticket price on Oct 31
$297
Fastest journey on Oct 31
1 d 16 h 15 m
Average journey duration on Oct 31
1 d 16 h 35 m
Buses on Oct 31
2
Distance
1588 km
The best way to find a cheap bus ticket from Syracuse, NY to Gainesville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Gainesville, FL will cost around $297 if you buy it on the day, but the cheapest tickets can be found for only $290.
On Sat, Oct 31, we found 2 buses from Syracuse, NY to Gainesville, FL, including 2 direct services.
On Sat, Oct 31 the direct buses cover the 1588 km distance in an average of 1 d 16 h 35 m but if you time it right, some buses will get you there in just 1 d 16 h 15 m .
On Sat, Oct 31 the slowest buses will take 1 d 16 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Syracuse, NY to Gainesville, FL run on average 6 times per day, taking around 29h 51m. Cheap bus tickets for this journey start at $180 (€151) if you book in advance.
The earliest bus runs at 00:25, the last at 21:00. The fastest bus covers the 986 miles (1588 km) distance in 28h 35m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Syracuse, NY to Gainesville, FL.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:20AM | Arrival Time 05:15PM | Duration 40h55 | Departure days Sat | Cheapest price $290 |
Operator FlixBus | Departure Time 01:00AM | Arrival Time 05:15PM | Duration 40h15 | Departure days Sat | Cheapest price $304 |
The table below shows live departures for Syracuse, NY to Gainesville, FL buses for tomorrow, Friday, October 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:20 AM Syracuse, NY | 40h55 | 5:15 PM Gainesville, FL | 0 transfersDirect | |
![]() | 1:00 AM Syracuse, NY | 40h15 | 5:15 PM Gainesville, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Syracuse, NY to Gainesville, FL with FlixBus and Greyhound. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Gainesville, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Gainesville, FL trip today.
Natural history museum with Florida fossils, butterfly exhibits, and family-friendly science displays on the University of Florida campus.
University art museum featuring global collections, rotating exhibitions, and strong photography and modern art presentations.
Tree-lined downtown district with historic buildings, murals, music venues, and an easy walk to shops, theaters, and public art.
Tree-lined downtown district with historic buildings, murals, music venues, and an easy walk to shops, theaters, and public art.
Large wetlands park with boardwalks, wildlife viewing, and broad views over marshes that attract birds, alligators, and photographers.
Lively student-centered district near UF with shops, nightlife, murals, and walkable streets that capture the city's college-town energy.
North Florida barbecue often features slow-smoked pork or brisket with tangy sauces, reflecting Southern pit traditions common at local gatherings and roadside smokehouses.
Fresh Gulf shrimp are a Florida staple, commonly boiled, fried, or served in baskets. Gainesville restaurants highlight this regional seafood from nearby Gulf waters.
This Florida classic layers tart Key lime juice, sweetened condensed milk, and a crumb crust. It is a signature state dessert found widely in Gainesville.
Long-running barbecue spot serving smoked meats, classic sides, and a casual local atmosphere near downtown.
Stylish downtown venue focused on modern Southern food, oysters, and cocktails in an energetic setting.
Refined Southern restaurant known for seasonal plates, cocktails, and a polished but relaxed downtown setting.
Moderate for U.S. college towns: hotels can rise on game days, dining is reasonable, and most visitors need a car or rideshares.
Tip 18-20% at restaurants, 15-20% for taxis and rideshares, and $1-2 per drink or coffee is appreciated.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Gainesville, FL.
Find answers to the most common questions about traveling from Syracuse, NY to Gainesville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Gainesville, FL, this guide helps you travel smarter and with confidence.

Most Syracuse, NY to Gainesville, FL buses use the Syracuse, Walsh Cir (Syracuse Bus Station) to Gainesville, NW 23rd St (North Walmart Supercenter) station pair, with some services arriving at Gainesville, Rosa Parks Transfer station. Use this guide to compare Syracuse, NY and Gainesville, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Gainesville, Rosa Parks Transfer station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi is available at the station. ATMs are available at Gainesville, Rosa Parks Transfer station.
Ticket office support is available at Gainesville, Rosa Parks Transfer station.
Available at Gainesville, Rosa Parks Transfer station: Parking, Taxis, WC.
Accessibility facilities are available at Gainesville, Rosa Parks Transfer station: The station is wheelchair accessible.
Gainesville, NW 23rd St (North Walmart Supercenter) is 7 km from Gainesville city centre. Public transport options include:
Gainesville, NW 23rd St (North Walmart Supercenter) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Gainesville, NW 23rd St (North Walmart Supercenter). ATMs are available at Gainesville, NW 23rd St (North Walmart Supercenter).
Ticket office support is available at Gainesville, NW 23rd St (North Walmart Supercenter).
Available at Gainesville, NW 23rd St (North Walmart Supercenter): Parking, Taxis, WC.
Accessibility facilities are available at Gainesville, NW 23rd St (North Walmart Supercenter): Bus stop has basic accessibility features.
Check bus stations information for Syracuse, NY and Gainesville, FL, including where buses depart and arrive on this route.