- Must visit
Columbus Museum of Art
Major art museum known for American and European collections, strong modern and contemporary holdings, and rotating exhibitions in a central downtown setting.
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The cheapest and fastest buses from St. Louis, MO to Columbus, OH
Showing times and prices for Jun 20
Cheapest price
$109
Average price
$119
Fastest journey
10 h 40 m
Average duration
11 h 30 m
Buses per day
4
Distance
637 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Columbus, OH will cost around $119 if you buy it on the day, but the cheapest tickets can be found for only $109.
Fast buses
Of the 4 buses that leave St. Louis, MO for Columbus, OH on Sat, Jun 20, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 637 km distance in an average of 11 h 30 m but if you time it right, some buses will get you there in just 10 h 40 m .
On Sat, Jun 20 the slowest buses will take 12 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
8:45 AM11h05St. Louis, MO7:50 PMColumbus, OH$1091One-way1 transfer- 2:00 AM11h55St. Louis, MO1:55 PMColumbus, OH$1221One-way0 transfers
- 8:45 AM12h20St. Louis, MO9:05 PMColumbus, OH$1221One-way0 transfers
- 1:55 PM10h40St. Louis, MO12:35 AMColumbus, OH$1221One-way0 transfers
- 1:55 PM10h40St. Louis, MO12:35 AMColumbus, OH$1221One-way0 transfers
- 8:45 AM11h05St. Louis, MO7:50 PMColumbus, OH$1091One-way1 transfer
- 2:00 AM11h55St. Louis, MO1:55 PMColumbus, OH$1221One-way0 transfers
- 8:45 AM12h20St. Louis, MO9:05 PMColumbus, OH$1221One-way0 transfers
Travel Information
Compare bus and flight for St. Louis, MO to Columbus, OH
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Columbus, OH among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a flight which can get you there in 2h 53m. The ticket price range depends on the travel mode: a bus costs an average of $52, and a flight costs an average of $164.
Distance: 395 miles (637 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$73 Average price Cheapest | $262 Average price | $84 Average price (fuel + tolls) |
11h 3m Average total duration 10h 33m Onboard + 30m Additional time* | 5h 53m Average total duration Fastest 2h 53m Onboard + 3h 0m Additional time* | 6h 17m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Columbus, OH is a bus with an average price of $73 (€60).
This is compared to other travel options from St. Louis, MO to Columbus, OH:
A bus is $189 (€155) less than a flight for this route with tickets for a flight from St. Louis, MO to Columbus, OH costing on average $262 (€215).
The fastest way to travel from St. Louis, MO to Columbus, OH is by flight with an average journey time of 2h 53m.
Other travel options to Columbus, OH take longer:
Bus takes on average 10h 33m.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and Columbus, OH including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Columbus, OH among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $73 (€60) compared to roughly $84 (€69) in fuel and tolls — a saving of about $11 (€9). The journey takes 10h 33m versus 6h 17m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
St. Louis, MO to Columbus, OH Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 02:00AM | Arrival Time 01:55PM | Duration 11h55 | Departure days Everyday | Cheapest price $52 |
Operator Greyhound USA | Departure Time 08:45AM | Arrival Time 07:50PM | Duration 11h05 | Departure days Everyday | Cheapest price $52 |
Operator FlixBus | Departure Time 10:00AM | Arrival Time 03:40AM | Duration 16h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $90 |
Operator Greyhound USA | Departure Time 01:55PM | Arrival Time 12:35AM | Duration 10h40 | Departure days Everyday | Cheapest price $54 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 05:10PM | Duration 16h40 | Departure days Thu, Fri, Sun | Cheapest price $92 |
Live departures
St. Louis, MO to Columbus, OH bus times
The table below shows live departures for St. Louis, MO to Columbus, OH buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:55 PM St. Louis, S 15th St (Civic center) | 9h40 | 12:35 AM Columbus, E Mound St (Akili Christian High School), OH | 0 transfersDirect | |
| Saturday, June 20 | |||||
| 2:00 AM St. Louis, MO | 11h55 | 1:55 PM Columbus, OH | 0 transfersDirect | |
| Friday, June 19 | |||||
 FlixBus · FlixBus | 11:30 PM St. Louis, S 15th St (Civic center) | 16h40 | 5:10 PM Columbus, E Town St (Bus Station), OH | 1 transfer | |
| Saturday, June 20 | |||||
| 8:45 AM St. Louis, MO | 11h05 | 7:50 PM Columbus, OH | 1 transfer | |
| 8:45 AM St. Louis, MO | 12h20 | 9:05 PM Columbus, OH | 0 transfersDirect | |
| 1:55 PM St. Louis, MO | 10h40 | 12:35 AM Columbus, OH | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Columbus, OH by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Columbus, OH buses with Omio?
Greyhound operates all buses services from St. Louis, MO to Columbus, OH.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Columbus, OH.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Columbus, OH.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from St. Louis, MO to Columbus, OH.
Journey information
Overview: Bus from St. Louis, MO to Columbus, OH
USAUSA
Buses from St. Louis, MO to Columbus, OH run on average 4 times per day, taking around 10h 33m. Cheap bus tickets for this journey start at $52 (€43) if you book in advance.
There are 3 buses per day. The earliest bus runs at 02:00, the last at 23:50. The fastest bus covers the 395 miles (637 km) distance in 9h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 395 miles (637 km) |
Average bus duration 10h 33m |
Cheapest ticket price $52 (€43) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 9h 40m |
First bus 2:00 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 42 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from St. Louis, MO to Columbus, OHYou can travel by bus between St. Louis, MO to Columbus, OH with Greyhound for as low as $52 (€43). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 40m
Cheapest Price
$52 (€43)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Columbus
Things to do in Columbus
Discover the best of Columbus — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus trip today.
- Must visit
COSI
Large science museum with hands-on exhibits, a planetarium, and family-friendly interactive galleries on the Scioto riverfront.
- Recommended
Wexner Center for the Arts
Contemporary art center at The Ohio State University featuring exhibitions, film, and experimental visual culture in a notable modern building.
- Must visit
Short North Arts District
Columbus's best-known walkable district for galleries, murals, boutiques, and nightlife, with strong street life and high visitor appeal.
- Must visit
Scioto Mile
Riverfront park system with promenades, bridges, lawns, and skyline views, ideal for walking, biking, and sunset photos.
- Must visit
German Village
Historic brick neighborhood known for preserved streetscapes, charming houses, and one of the city's most distinctive walking environments.
Columbus-Style Pizza
Thin-crust pizza cut into squares, a long-standing local favorite in Columbus pizzerias. It is known for a crisp crust and edge-to-edge toppings.
- Vegetarian
- Gluten-free
Buckeye Candy
A classic Ohio sweet made from peanut butter fudge partially dipped in chocolate to resemble the buckeye nut. It is one of the region’s most recognizable treats.
Johnny Marzetti
A baked pasta casserole with ground beef, tomato sauce, cheese, and noodles. It is strongly associated with Columbus and central Ohio home cooking.
Lindey’s
Established upscale American restaurant in German Village, known for polished service, a classic menu, and a refined patio setting.
Katzinger’s Delicatessen
Beloved German Village deli serving stacked sandwiches, Jewish deli classics, and casual counter-service comfort food.
Mitchell’s Ocean Club
Polished fine-dining steak and seafood restaurant at Easton, known for a sophisticated atmosphere and special-occasion dining.
United States Dollar
Moderate by U.S. standards. Meals and transport are reasonable, while downtown hotels and fine dining cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a casual lunch.
- Mid-range
- USD 20-35 per person at a mid-range restaurant.
- Fine dining
- USD 60-100+ per person at upscale restaurants.
- Coffee
- USD 4-6 for a coffee drink.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 1-5, and round up for coffee jars if desired.
FAQs: Bus from St. Louis, MO to Columbus, OH
Find answers to the most common questions about traveling from St. Louis, MO to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Columbus, OH can start from as little as $52 (€43) when you book in advance. The average bus ticket price for St. Louis, MO to Columbus, OH is $73 (€60) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Columbus, OH is 9h 40m to travel the 395 miles (637 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Columbus, OH leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Columbus, OH leaves at 11:50 PM.
Yes, there are 3 direct buses a day from St. Louis, MO to Columbus, OH with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from St. Louis, MO to Columbus, OH, you can count on Greyhound for the best way to get you to Columbus, OH. You can also check all possible bus companies who offer a service between St. Louis, MO and Columbus, OH and compare the amenities they offer before buying a bus ticket.
A trip to Columbus, OH from St. Louis, MO is worth doing but not as a day trip with a journey time of 9h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Columbus, OH is February.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and Columbus, OH including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Columbus, OH:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Columbus, OH for bus company Greyhound.
Some of the most interesting sights to explore in Columbus, OH are:
- Columbus Zoo and Aquarium, a renowned zoo featuring diverse animal exhibits and conservation programs
- Franklin Park Conservatory and Botanical Gardens, a horticultural landmark with seasonal exhibitions and a stunning glasshouse
- Ohio Statehouse, a Greek Revival-style capitol building offering guided tours and historical insights
- Scioto Mile, a scenic urban oasis with parks, fountains, and trails along the Scioto River
- Wexner Center for the Arts, a contemporary art gallery showcasing innovative exhibitions and performances.
The best things to do in Columbus, OH include:
- COSI (Center of Science and Industry), an interactive science museum offering hands-on exhibits and educational programs
- Short North Arts District, a vibrant neighborhood known for its art galleries, boutiques, and dining options
- German Village, a historic area with charming brick streets, unique shops, and traditional German cuisine
- North Market, a bustling public market featuring diverse food vendors and local products
- Columbus Museum of Art, offering engaging exhibitions and a dynamic collection of American and European art.
Whether you can cancel your bus ticket from St. Louis, MO to Columbus, OH depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Columbus, OH.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Columbus, OH:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Columbus, OH:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Columbus, OH.
You can reserve your seat on the bus from St. Louis, MO to Columbus, OH with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Columbus, OH with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Columbus, OH with the following bus company: Greyhound.
Since neither St. Louis, MO nor Columbus, OH are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Columbus, OH among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Columbus, OH, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular nightlife districts. Common scams include overcharging by unofficial taxi services and fake ticket sellers for events. It's advisable to use authorized transportation options and stay in well-lit, populated areas to enhance safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Columbus, OH
St. Louis
Columbus
The major bus station for departures in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip from St. Louis to Columbus.
St. Louis, S 15th St (Civic center)
information
The major bus station for arrivals in Columbus is Columbus, E Town St (Bus Station). Find all the information you need to know about services, amenities and connections at Columbus, E Town St (Bus Station) for your trip to Columbus from St. Louis.
Columbus, E Town St (Bus Station)
information
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Columbus, OH
Here are some other resources that might have the information you need
Most popular buses to and from Columbus, OH and St. Louis, MO
Most popular bus connections to Columbus, OH
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