- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
Cheapest price
$84
Average price
$92
Fastest journey
7 h 40 m
Average duration
8 h 18 m
Buses per day
2
Distance
482 km
The best way to find a cheap bus ticket from Frederick, MD to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Columbus, OH will cost around $92 if you buy it on the day, but the cheapest tickets can be found for only $84.
Of the 2 buses that leave Frederick, MD for Columbus, OH on Thu, Jul 30, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 30 the direct buses cover the 482 km distance in an average of 8 h 18 m but if you time it right, some buses will get you there in just 7 h 40 m .
On Thu, Jul 30 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Frederick, MD to Columbus, OH among Omio's users. If you are prioritising price take the bus with prices starting from $78. For those with little time consider booking a flight which can get you there in 4h 57m. The ticket price range depends on the travel mode: a bus costs an average of $78, and a flight costs an average of $253.
Distance: 299 miles (482 km)
Most popular Bus | Flight |
|---|---|
$102 Average price Cheapest | $310 Average price |
7h 40m Average total duration 7h 10m Onboard + 30m Additional time* | 7h 57m Average total duration Fastest 4h 57m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Columbus, OH:
A bus is $209 (€172) less than a flight for this route with tickets for a flight from Frederick, MD to Columbus, OH costing on average $310 (€256).
Other travel options to Columbus, OH take longer:
Bus takes on average 7h 10m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 09:45AM | Duration 9h10 | Departure days Wed | Cheapest price $79 |
Operator Greyhound | Departure Time 10:45AM | Arrival Time 06:25PM | Duration 7h40 | Departure days Thu, Fri, Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 03:20AM | Duration 13h00 | Departure days Sat | Cheapest price $79 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 04:20AM | Duration 12h55 | Departure days Sat | Cheapest price $79 |
Operator Greyhound | Departure Time 11:35PM | Arrival Time 08:30AM | Duration 8h55 | Departure days Mon, Tue, Wed, Thu | Cheapest price $79 |
The table below shows live departures for Frederick, MD to Columbus, OH buses for today, Wednesday, July 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:35 PM Frederick, MD | 8h55 | 8:30 AM Columbus, OH | 0 transfersDirect | |
| Thursday, July 30 | |||||
![]() | 10:45 AM Frederick, MD | 7h40 | 6:25 PM Columbus, OH | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Columbus, OH run on average 2 times per day, taking around 7h 10m. Cheap bus tickets for this journey start at $78 (€64) if you book in advance.
The earliest bus runs at 00:30, the last at 21:10. The fastest bus covers the 299 miles (482 km) distance in 7h 40m.
Distance 299 miles (482 km) |
Average bus duration 7h 10m |
Cheapest ticket price $78 (€64) |
Buses per day 2 |
Fastest bus 7h 40m |
First bus 12:30 AM |
Last bus 9:10 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Fri |
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Find answers to the most common questions about traveling from Frederick, MD to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Columbus, OH buses use the Frederick, East Street (Transit Center) to Columbus, E Town St (Bus Station) station pair. Use this guide to compare Frederick, MD and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need