- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
Cheapest price on Sep 14
$168
Average ticket price on Sep 14
$168
Fastest journey on Sep 14
9 h 10 m
Average journey duration on Sep 14
9 h 10 m
Buses on Sep 14
1
Distance
482 km
The best way to find a cheap bus ticket from Frederick, MD to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Columbus, OH will cost around $168 if you buy it on the day, but the cheapest tickets can be found for only $168.
On Mon, Sep 14, we found 1 buses from Frederick, MD to Columbus, OH, including 1 direct services.
On Mon, Sep 14 the direct buses cover the 482 km distance in an average of 9 h 10 m but if you time it right, some buses will get you there in just 9 h 10 m .
On Mon, Sep 14 the slowest buses will take 9 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Frederick, MD to Columbus, OH among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $122 For those with little time, consider booking a flight, which has an average total journey time of 5h 50m. Average ticket prices depend on the travel mode: a bus costs an average of $122, while a flight costs an average of $634.
Distance: 299 miles (482 km)
Most popular Bus | Flight |
|---|---|
$122 Average price Cheapest | $634 Average price |
9h 41m Average total duration 9h 11m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 3h 50m Onboard + 2h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Columbus, OH:
A bus is $512 less than a flight for this route with tickets for a flight from Frederick, MD to Columbus, OH costing on average $634.
Other travel options to Columbus, OH take longer:
Bus takes on average 9h 11m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 09:45AM | Duration 9h10 | Departure days Wed | Cheapest price $80 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 11:20PM | Duration 12h55 | Departure days Thu | Cheapest price $70 |
Operator Greyhound | Departure Time 10:45AM | Arrival Time 06:25PM | Duration 7h40 | Departure days Fri, Sun | Cheapest price $83 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 03:20AM | Duration 13h00 | Departure days Sat | Cheapest price $81 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 04:20AM | Duration 12h55 | Departure days Sat | Cheapest price $81 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 04:35AM | Duration 9h00 | Departure days Thu | Cheapest price $68 |
Operator Greyhound | Departure Time 11:35PM | Arrival Time 08:30AM | Duration 8h55 | Departure days Mon, Tue, Wed | Cheapest price $80 |
Operator Greyhound | Departure Time 11:40PM | Arrival Time 01:55PM | Duration 14h15 | Departure days Thu | Cheapest price $87 |
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Columbus, OH run on average 3 times per day, taking around 9h 11m. Cheap bus tickets for this journey start at $110 if you book in advance.
The earliest bus runs at 00:30, the last at 21:10. The fastest bus covers the 299 miles (482 km) distance in 7h 25m.
Distance 299 miles (482 km) |
Average bus duration 9h 11m |
Cheapest ticket price $110 |
Buses per day 3 |
Fastest bus 7h 25m |
First bus 12:30 AM |
Last bus 9:10 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Fri |
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Find answers to the most common questions about traveling from Frederick, MD to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Columbus, OH buses use the Frederick, East Street (Transit Center) to Columbus, E Mound St (Akili Christian High School) station pair, with some services arriving at Columbus, E Town St (Bus Station). Use this guide to compare Frederick, MD and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Ticket office support is available at Frederick, East Street (Transit Center).
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
Here are some other resources that might have the information you need