- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
Buses from San Diego, CA to Columbus, OH run on average 8 times per day, taking around 52h 48m. Cheap bus tickets for this journey start at $223 (€187) if you book in advance.
The earliest bus runs at 02:45, the last at 23:50. The fastest bus covers the 1952 miles (3143 km) distance in 50h 25m.
Distance 1952 miles (3143 km) |
Average bus duration 52h 48m |
Cheapest ticket price $223 (€187) |
Buses per day 8 |
Fastest bus 50h 25m |
First bus 2:45 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Oct - Dec |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:15AM | Arrival Time 07:50PM | Duration 55h35 | Departure days Thu | Cheapest price $256 |
Operator Greyhound | Departure Time 09:25AM | Arrival Time 12:45AM | Duration 60h20 | Departure days Thu | Cheapest price $414 |
Operator Greyhound | Departure Time 09:50AM | Arrival Time 07:50PM | Duration 55h00 | Departure days Thu | Cheapest price $395 |
Operator Greyhound | Departure Time 11:45AM | Arrival Time 03:40AM | Duration 60h55 | Departure days Thu | Cheapest price $414 |
Operator Greyhound | Departure Time 12:40PM | Arrival Time 12:45AM | Duration 57h05 | Departure days Thu | Cheapest price $277 |
Operator Greyhound | Departure Time 01:10PM | Arrival Time 03:40AM | Duration 59h30 | Departure days Thu | Cheapest price $414 |
Operator Greyhound | Departure Time 05:15PM | Arrival Time 02:05AM | Duration 56h50 | Departure days Mon | Cheapest price $225 |
Operator Greyhound | Departure Time 07:10PM | Arrival Time 07:45AM | Duration 57h35 | Departure days Thu | Cheapest price $340 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 05:10PM | Duration 66h25 | Departure days Thu | Cheapest price $405 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 04:35AM | Duration 56h25 | Departure days Sun | Cheapest price $191 |
Operator Greyhound | Departure Time 10:15PM | Arrival Time 03:40AM | Duration 74h25 | Departure days Thu | Cheapest price $445 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 03:40AM | Duration 74h05 | Departure days Thu | Cheapest price $445 |
The table below shows live departures for San Diego, CA to Columbus, OH buses for today, Thursday, October 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · + FlixBus | 9:15 AM San Diego, San Ysidro Transit Center | 55h35 | 7:50 PM Columbus, E Town St (Bus Station), OH | 3 transfers | |
· · | 9:15 AM San Diego, San Ysidro Transit Center | 56h25 | 8:40 PM Columbus, E Mound St (Akili Christian High School), OH | 2 transfers | |
FlixBus · FlixBus+ · | 9:25 AM San Diego, Congress Street (Old Town Park), CA | 60h20 | 12:45 AM Columbus, E Mound St (Akili Christian High School), OH | 5 transfers | |
FlixBus · FlixBus+ · | 9:25 AM San Diego, Congress Street (Old Town Park), CA | 63h15 | 3:40 AM Columbus, E Town St (Bus Station), OH | 5 transfers | |
· · | 9:50 AM San Diego, Congress Street (Old Town Park), CA | 55h50 | 8:40 PM Columbus, E Mound St (Akili Christian High School), OH | 2 transfers | |
· · + FlixBus | 9:50 AM San Diego, Congress Street (Old Town Park), CA | 55h00 | 7:50 PM Columbus, E Town St (Bus Station), OH | 3 transfers | |
· · + FlixBus | 11:45 AM San Diego, Congress Street (Old Town Park), CA | 60h55 | 3:40 AM Columbus, E Town St (Bus Station), OH | 3 transfers | |
FlixBus+ · · | 12:40 PM San Diego, San Ysidro Transit Center | 57h05 | 12:45 AM Columbus, E Mound St (Akili Christian High School), OH | 4 transfers | |
FlixBus+ · · | 12:40 PM San Diego, San Ysidro Transit Center | 60h00 | 3:40 AM Columbus, E Town St (Bus Station), OH | 4 transfers | |
FlixBus+ · · | 1:10 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 59h30 | 3:40 AM Columbus, E Town St (Bus Station), OH | 4 transfers | |
FlixBus+ · · | 1:10 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 56h35 | 12:45 AM Columbus, E Mound St (Akili Christian High School), OH | 4 transfers | |
· · · | 7:10 PM San Diego, San Ysidro Transit Center | 57h35 | 7:45 AM Columbus, E Mound St (Akili Christian High School), OH | 3 transfers | |
· · · | 7:45 PM San Diego, Congress Street (Old Town Park), CA | 57h00 | 7:45 AM Columbus, E Mound St (Akili Christian High School), OH | 3 transfers | |
· · · | 7:45 PM San Diego, Congress Street (Old Town Park), CA | 66h25 | 5:10 PM Columbus, E Town St (Bus Station), OH | 4 transfers | |
FlixBus+ · · | 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 74h25 | 3:40 AM Columbus, E Town St (Bus Station), OH | 4 transfers | |
FlixBus+ · · | 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 71h30 | 12:45 AM Columbus, E Mound St (Akili Christian High School), OH | 4 transfers | |
FlixBus+ · · | 10:35 PM San Diego, Congress Street (Old Town Park), CA | 74h05 | 3:40 AM Columbus, E Town St (Bus Station), OH | 4 transfers | |
FlixBus+ · · | 10:35 PM San Diego, Congress Street (Old Town Park), CA | 71h10 | 12:45 AM Columbus, E Mound St (Akili Christian High School), OH | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Find answers to the most common questions about traveling from San Diego, CA to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most San Diego, CA to Columbus, OH buses use the San Diego, Congress Street (Old Town Park) to Columbus, E Mound St (Akili Christian High School) station pair, with some services arriving at Columbus, E Town St (Bus Station). Use this guide to compare San Diego, CA and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several dining options nearby.
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food eateries located nearby.
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Ticket office support is available at San Diego, San Ysidro Transit Center.
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several dining options are in the area.
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
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