- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
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The cheapest and fastest buses from Columbus, OH to St. Louis, MO
Showing times and prices for Jun 21
Cheapest price
$71
Average price
$84
Fastest journey
9 h 5 m
Average duration
12 h 15 m
Buses per day
5
Distance
637 km
Cheap tickets
The best way to find a cheap bus ticket from Columbus, OH to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbus, OH to St. Louis, MO will cost around $84 if you buy it on the day, but the cheapest tickets can be found for only $71.
Fast buses
Of the 5 buses that leave Columbus, OH for St. Louis, MO on Sun, Jun 21, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 637 km distance in an average of 12 h 15 m but if you time it right, some buses will get you there in just 9 h 5 m .
On Sun, Jun 21 the slowest buses will take 17 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:40 AM11h30Columbus, E Mound St (Akili Christian High School), OH3:10 PMSt. Louis, S 15th St (Civic center)$711One-way0 transfers- 11:50 PM9h05Columbus, E Mound St (Akili Christian High School), OH7:55 AMSt. Louis, S 15th St (Civic center)$731One-way0 transfers
- 2:00 PM10h15Columbus, E Mound St (Akili Christian High School), OH11:15 PMSt. Louis, S 15th St (Civic center)$771One-way0 transfers
FlixBus+11:00 AM13h15Columbus, E Town St (Bus Station), OH11:15 PMSt. Louis, S 15th St (Civic center)$1001One-way1 transfer- FlixBus · FlixBus11:30 PM17h10Columbus, E Town St (Bus Station), OH3:40 PMSt. Louis, S 15th St (Civic center)$1011One-way1 transfer
- 11:50 PM9h05Columbus, E Mound St (Akili Christian High School), OH7:55 AMSt. Louis, S 15th St (Civic center)$731One-way0 transfers
- 2:00 PM10h15Columbus, E Mound St (Akili Christian High School), OH11:15 PMSt. Louis, S 15th St (Civic center)$771One-way0 transfers
- 4:40 AM11h30Columbus, E Mound St (Akili Christian High School), OH3:10 PMSt. Louis, S 15th St (Civic center)$711One-way0 transfers
- FlixBus+11:00 AM13h15Columbus, E Town St (Bus Station), OH11:15 PMSt. Louis, S 15th St (Civic center)$1001One-way1 transfer
- FlixBus · FlixBus11:30 PM17h10Columbus, E Town St (Bus Station), OH3:40 PMSt. Louis, S 15th St (Civic center)$1011One-way1 transfer
Travel Information
Compare bus and flight for Columbus, OH to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Columbus, OH to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a flight which can get you there in 6h 13m. The ticket price range depends on the travel mode: a bus costs an average of $53, and a flight costs an average of $127.
Distance: 395 miles (637 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$65 Average price Cheapest | $238 Average price | $84 Average price (fuel + tolls) |
9h 39m Average total duration 9h 9m Onboard + 30m Additional time* | 9h 13m Average total duration Fastest 6h 13m Onboard + 3h 0m Additional time* | 6h 16m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Columbus, OH to St. Louis, MO is a bus with an average price of $65 (€53).
This is compared to other travel options from Columbus, OH to St. Louis, MO:
A bus is $173 (€142) less than a flight for this route with tickets for a flight from Columbus, OH to St. Louis, MO costing on average $238 (€195).
The fastest way to travel from Columbus, OH to St. Louis, MO is by flight with an average journey time of 6h 13m.
Other travel options to St. Louis, MO take longer:
Bus takes on average 9h 9m.
It's helpful to compare your options as there are 2 ways to travel between Columbus, OH and St. Louis, MO including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Columbus, OH to St. Louis, MO among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $65 (€53) compared to roughly $84 (€69) in fuel and tolls — a saving of about $19 (€16). The journey takes 9h 9m versus 6h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Columbus, OH to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:40AM | Arrival Time 03:10PM | Duration 11h30 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $50 |
Operator Greyhound | Departure Time 08:35AM | Arrival Time 08:10PM | Duration 11h35 | Departure days Mon, Wed | Cheapest price $54 |
Operator Greyhound | Departure Time 08:40AM | Arrival Time 08:10PM | Duration 11h30 | Departure days Wed | Cheapest price $56 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 11:15PM | Duration 14h30 | Departure days Thu, Fri | Cheapest price $76 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 11:15PM | Duration 13h15 | Departure days Tue, Sat, Sun | Cheapest price $81 |
Operator Greyhound | Departure Time 02:00PM | Arrival Time 11:15PM | Duration 10h15 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $51 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 04:25AM | Duration 9h55 | Departure days Mon | Cheapest price $89 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 03:40PM | Duration 17h10 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $78 |
Operator Greyhound | Departure Time 11:50PM | Arrival Time 07:55AM | Duration 9h05 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $53 |
Live departures
Columbus, OH to St. Louis, MO bus times
The table below shows live departures for Columbus, OH to St. Louis, MO buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 2:00 PM Columbus, E Mound St (Akili Christian High School), OH | 10h15 | 11:15 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| FlixBus · FlixBus | 11:30 PM Columbus, E Town St (Bus Station), OH | 17h10 | 3:40 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| 11:50 PM Columbus, E Mound St (Akili Christian High School), OH | 9h05 | 7:55 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| Sunday, June 21 | |||||
| 4:40 AM Columbus, E Mound St (Akili Christian High School), OH | 11h30 | 3:10 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| FlixBus+ | 11:00 AM Columbus, E Town St (Bus Station), OH | 13h15 | 11:15 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Columbus, OH to St. Louis, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 21
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Why should you book Columbus, OH to St. Louis, MO buses with Omio?
Greyhound operates all buses services from Columbus, OH to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Columbus, OH to St. Louis, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Columbus, OH to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Columbus, OH to St. Louis, MO.
Journey information
Overview: Bus from Columbus, OH to St. Louis, MO
USAUSA
Buses from Columbus, OH to St. Louis, MO run on average 5 times per day, taking around 9h 9m. Cheap bus tickets for this journey start at $53 (€43) if you book in advance.
There are 3 buses per day. The earliest bus runs at 02:00, the last at 23:50. The fastest bus covers the 395 miles (637 km) distance in 9h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 395 miles (637 km) |
Average bus duration 9h 9m |
Cheapest ticket price $53 (€43) |
Buses per day 5 |
Direct buses 3 |
Fastest bus 9h 5m |
First bus 2:00 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Best time to book 7 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Columbus, OH to St. Louis, MOYou can travel by bus between Columbus, OH to St. Louis, MO with Greyhound for as low as $53 (€43). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 5m
Cheapest Price
$53 (€43)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis
Things to do in St. Louis
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
- Must visit
City Museum
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
- Recommended
Missouri History Museum
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
- Must visit
Forest Park
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
- Must visit
Gateway Arch National Park Grounds
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
- Recommended
The Delmar Loop
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
- Vegetarian
St. Louis-Style Pizza
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Toasted Ravioli
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
- Vegetarian
Gooey Butter Cake
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
Charlie Gitto's On The Hill
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
Ted Drewes Frozen Custard
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
Sidney Street Cafe
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
United States Dollar
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Average meal costs
- Budget
- USD 10-18 for fast food or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 70+ per person before drinks and tip.
- Coffee
- USD 3-6 for regular coffee or a latte.
Tipping culture
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from Columbus, OH to St. Louis, MO
Find answers to the most common questions about traveling from Columbus, OH to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Columbus, OH to St. Louis, MO can start from as little as $53 (€43) when you book in advance. The average bus ticket price for Columbus, OH to St. Louis, MO is $65 (€53) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Columbus, OH to St. Louis, MO is 9h 5m to travel the 395 miles (637 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Columbus, OH to St. Louis, MO leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Columbus, OH to St. Louis, MO leaves at 11:50 PM.
Yes, there are 3 direct buses a day from Columbus, OH to St. Louis, MO with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Columbus, OH to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Columbus, OH and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
A trip to St. Louis, MO from Columbus, OH is worth doing but not as a day trip with a journey time of 9h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Columbus, OH to St. Louis, MO is September.
It's helpful to compare your options as there are 2 ways to travel between Columbus, OH and St. Louis, MO including taking a bus and flight.
Yes, there are bathrooms on board the bus from Columbus, OH to St. Louis, MO for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Columbus, OH to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Columbus, OH to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Columbus, OH to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Columbus, OH to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Columbus, OH to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Columbus, OH to St. Louis, MO.
You can reserve your seat on the bus from Columbus, OH to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Columbus, OH to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Columbus, OH to St. Louis, MO with the following bus company: Greyhound.
Since neither Columbus, OH nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Columbus, OH to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Columbus, OH to St. Louis, MO
Columbus
St. Louis
The major bus station for departures in Columbus is Columbus, E Town St (Bus Station). Find all the information you need to know about services, amenities and connections at Columbus, E Town St (Bus Station) for your trip from Columbus to St. Louis.
Columbus, E Town St (Bus Station)
information
The major bus station for arrivals in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip to St. Louis from Columbus.
St. Louis, S 15th St (Civic center)
information
Most popular bus connections from Columbus, OH
More options for your journey from Columbus, OH to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Columbus, OH
Most popular bus connections to St. Louis, MO
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