- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
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The cheapest and fastest buses from Columbus, OH to St. Louis, MO
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
$63
Average ticket price on Sep 19
$93
Fastest journey on Sep 19
9 h 5 m
Average journey duration on Sep 19
12 h 15 m
Buses on Sep 19
5
Distance
637 km
Cheap tickets
The best way to find a cheap bus ticket from Columbus, OH to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbus, OH to St. Louis, MO will cost around $93 if you buy it on the day, but the cheapest tickets can be found for only $63.
Fast buses
On Sat, Sep 19, we found 5 buses from Columbus, OH to St. Louis, MO, including 3 direct services.
On Sat, Sep 19 the direct buses cover the 637 km distance in an average of 12 h 15 m but if you time it right, some buses will get you there in just 9 h 5 m .
On Sat, Sep 19 the slowest buses will take 17 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:40 AM11h30Columbus, E Mound St (Akili Christian High School), OH3:10 PMSt. Louis, S 15th St (Civic center)$631One-way0 transfers- 2:00 PM10h15Columbus, E Mound St (Akili Christian High School), OH11:15 PMSt. Louis, S 15th St (Civic center)$631One-way0 transfers
- 11:50 PM9h05Columbus, E Mound St (Akili Christian High School), OH7:55 AMSt. Louis, S 15th St (Civic center)$1121One-way0 transfers
FlixBus+11:00 AM13h15Columbus, E Town St (Bus Station), OH11:15 PMSt. Louis, S 15th St (Civic center)$1141One-way1 transfer- FlixBus · FlixBus11:30 PM17h10Columbus, E Town St (Bus Station), OH3:40 PMSt. Louis, S 15th St (Civic center)$1141One-way1 transfer
- 11:50 PM9h05Columbus, E Mound St (Akili Christian High School), OH7:55 AMSt. Louis, S 15th St (Civic center)$1121One-way0 transfers
- 2:00 PM10h15Columbus, E Mound St (Akili Christian High School), OH11:15 PMSt. Louis, S 15th St (Civic center)$631One-way0 transfers
- 4:40 AM11h30Columbus, E Mound St (Akili Christian High School), OH3:10 PMSt. Louis, S 15th St (Civic center)$631One-way0 transfers
- FlixBus+11:00 AM13h15Columbus, E Town St (Bus Station), OH11:15 PMSt. Louis, S 15th St (Civic center)$1141One-way1 transfer
- FlixBus · FlixBus11:30 PM17h10Columbus, E Town St (Bus Station), OH3:40 PMSt. Louis, S 15th St (Civic center)$1141One-way1 transfer
Travel Information
Compare bus and flight for Columbus, OH to St. Louis, MO
Omio recommends booking the flight as it is the most popular option from Columbus, OH to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $74 For those with little time, consider booking a flight, which has an average total journey time of 6h 14m. Average ticket prices depend on the travel mode: a bus costs an average of $74, while a flight costs an average of $687.
Distance: 395 miles (637 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$74 Average price Cheapest | $687 Average price | $85 Average price (fuel + tolls) |
10h 55m Average total duration 10h 25m Onboard + 30m Additional time* | 6h 14m Average total duration Fastest 4h 14m Onboard + 2h 0m Additional time* | 6h 16m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Columbus, OH to St. Louis, MO is a bus with an average price of $74.
This is compared to other travel options from Columbus, OH to St. Louis, MO:
A bus is $612 less than a flight for this route with tickets for a flight from Columbus, OH to St. Louis, MO costing on average $687.
The fastest way to travel from Columbus, OH to St. Louis, MO is by flight with an average journey time of 4h 14m.
Other travel options to St. Louis, MO take longer:
Bus takes on average 10h 25m.
It's helpful to compare your options as there are 2 ways to travel between Columbus, OH and St. Louis, MO including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Columbus, OH to St. Louis, MO among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $74 compared to roughly $85 in fuel and tolls — a saving of about $10. The journey takes 10h 25m versus 6h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Columbus, OH to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:40AM | Arrival Time 03:10PM | Duration 11h30 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $43 |
Operator Greyhound | Departure Time 09:45AM | Arrival Time 11:15PM | Duration 14h30 | Departure days Thu | Cheapest price $64 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 11:15PM | Duration 13h15 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $61 |
Operator Greyhound | Departure Time 02:00PM | Arrival Time 11:15PM | Duration 10h15 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 03:40PM | Duration 17h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $62 |
Operator Greyhound | Departure Time 11:50PM | Arrival Time 07:55AM | Duration 9h05 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $43 |
Live departures
Columbus, OH to St. Louis, MO bus times
The table below shows live departures for Columbus, OH to St. Louis, MO buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 11:30 PM Columbus, E Town St (Bus Station), OH | 17h10 | 3:40 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| Saturday, September 19 | |||||
| 4:40 AM Columbus, E Mound St (Akili Christian High School), OH | 11h30 | 3:10 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| FlixBus+ | 11:00 AM Columbus, E Town St (Bus Station), OH | 13h15 | 11:15 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
| 2:00 PM Columbus, E Mound St (Akili Christian High School), OH | 10h15 | 11:15 PM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Columbus, OH to St. Louis, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Columbus, OH to St. Louis, MO buses with Omio?
Greyhound as well as FlixBus offer buses services from Columbus, OH to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Columbus, OH to St. Louis, MO.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Columbus, OH to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Columbus, OH to St. Louis, MO.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Columbus, OH to St. Louis, MO.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Columbus, OH to St. Louis, MO.
Journey information
Overview: Bus from Columbus, OH to St. Louis, MO
USAUSA
Buses from Columbus, OH to St. Louis, MO run on average 5 times per day, taking around 10h 25m. Cheap bus tickets for this journey start at $50 if you book in advance.
There are 3 buses per day. The earliest bus runs at 02:00, the last at 23:50. The fastest bus covers the 395 miles (637 km) distance in 8h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 395 miles (637 km) |
Average bus duration 10h 25m |
Cheapest ticket price $50 |
Buses per day 5 |
Direct buses 3 |
Fastest bus 8h 45m |
First bus 2:00 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from Columbus, OH to St. Louis, MOYou can travel by bus between Columbus, OH to St. Louis, MO with Greyhound, FlixBus for as low as $50. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
13h 35m
Cheapest FlixBus Price
$60
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 45m
Cheapest Greyhound Price
$50
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Columbus, OH to St. Louis, MO
Find answers to the most common questions about traveling from Columbus, OH to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Columbus, OH to St. Louis, MO can start from as little as $50 when you book in advance. The average bus ticket price for Columbus, OH to St. Louis, MO is $74 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Columbus, OH to St. Louis, MO is 8h 45m to travel the 395 miles (637 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Columbus, OH to St. Louis, MO leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Columbus, OH to St. Louis, MO leaves at 11:50 PM.
Yes, there are 3 direct buses a day from Columbus, OH to St. Louis, MO with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Columbus, OH to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Columbus, OH and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
When departing from Columbus, OH , you have various bus station options to start your journey from including Columbus, E Mound St (Akili Christian High School), OH, Columbus, E Town St (Bus Station), OH . When arriving in St. Louis, MO , you can end your journey in bus stations like St. Louis, S 15th St (Civic center) .Passengers board the bus most frequently from Columbus, E Mound St (Akili Christian High School), OH, which is located around away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
A trip to St. Louis, MO from Columbus, OH is worth doing but not as a day trip with a journey time of 8h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Columbus, OH to St. Louis, MO is September.
It's helpful to compare your options as there are 2 ways to travel between Columbus, OH and St. Louis, MO including taking a bus and flight.
Yes, there are bathrooms on board the bus from Columbus, OH to St. Louis, MO for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Columbus, OH to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Columbus, OH to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Columbus, OH to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Columbus, OH to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Columbus, OH to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Columbus, OH to St. Louis, MO.
You can reserve your seat on the bus from Columbus, OH to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Columbus, OH to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Columbus, OH to St. Louis, MO with the following bus company: Greyhound.
Since neither Columbus, OH nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Columbus, OH to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Columbus, OH to St. Louis, MO
Most Columbus, OH to St. Louis, MO buses use the Columbus, E Mound St (Akili Christian High School) to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Columbus, OH and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Columbus
Arrival bus stations in St. Louis
Which Columbus, OH station do buses to St. Louis, MO leave from?
Buses from Columbus, OH to St. Louis, MO leave from Columbus, E Mound St (Akili Christian High School). The station is 0 miles (1 km) from Columbus, OH city centre at 600 Oakland Park Ave, Columbus, OH 43214, USA.
Columbus, E Mound St (Akili Christian High School)600 Oakland Park Ave, Columbus, OH 43214, USA
City-centre transport
Getting to Columbus, E Mound St (Akili Christian High School) from Columbus city centre
TRUE
Columbus, E Mound St (Akili Christian High School) bus station facilities and services
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Tickets and information
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Parking, taxis and toilets
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Columbus, E Town St (Bus Station)E Town St, Columbus, OH 43215, USA
City-centre transport
Getting to Columbus, E Town St (Bus Station) from Columbus city centre
TRUE
Columbus, E Town St (Bus Station) bus station facilities and services
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Tickets and information
Ticket office support is available at Columbus, E Town St (Bus Station).
Parking, taxis and toilets
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
Which St. Louis, MO station do buses from Columbus, OH arrive at?
Buses from Columbus, OH to St. Louis, MO arrive at St. Louis, S 15th St (Civic center). St. Louis, S 15th St (Civic center) is 0 miles (1 km) from St. Louis, MO city centre.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Most popular bus connections from Columbus, OH
More options for your journey from Columbus, OH to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Columbus, OH
Most popular bus connections to St. Louis, MO
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