- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
Cheapest price
$344
Average price
$344
Fastest journey
1 d 13 h
Average duration
1 d 13 h
Buses per day
1
Distance
1834 km
The best way to find a cheap bus ticket from San Antonio, TX to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Antonio, TX to Columbus, OH will cost around $344 if you buy it on the day, but the cheapest tickets can be found for only $344.
Of the 1 buses that leave San Antonio, TX for Columbus, OH on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 1834 km distance in an average of 1 d 13 h but if you time it right, some buses will get you there in just 1 d 13 h .
On Wed, Aug 05 the slowest buses will take 1 d 13 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Buses from San Antonio, TX to Columbus, OH run on average 5 times per day, taking around 35h 28m. Cheap bus tickets for this journey start at $159 if you book in advance.
The earliest bus runs at 01:30, the last at 23:50. The fastest bus covers the 1139 miles (1834 km) distance in 33h 30m.
Distance 1139 miles (1834 km) |
Average bus duration 35h 28m |
Cheapest ticket price $159 |
Buses per day 5 |
Fastest bus 33h 30m |
First bus 1:30 AM |
Last bus 11:50 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 11:45AM | Duration 35h30 | Departure days Tue | Cheapest price $379 |
Operator Greyhound USA | Departure Time 01:30AM | Arrival Time 07:45AM | Duration 30h15 | Departure days Tue, Fri, Sun | Cheapest price $154 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 11:45AM | Duration 33h30 | Departure days Fri | Cheapest price $296 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 12:45PM | Duration 33h30 | Departure days Fri | Cheapest price $231 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 08:40PM | Duration 37h50 | Departure days Tue | Cheapest price $286 |
Operator Greyhound | Departure Time 07:30AM | Arrival Time 07:50PM | Duration 35h20 | Departure days Fri | Cheapest price $163 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 07:50PM | Duration 35h05 | Departure days Fri | Cheapest price $163 |
Operator Greyhound | Departure Time 11:50AM | Arrival Time 12:50AM | Duration 37h00 | Departure days Wed | Cheapest price $344 |
Operator Greyhound | Departure Time 12:30PM | Arrival Time 01:05AM | Duration 36h35 | Departure days Thu | Cheapest price $299 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 03:40AM | Duration 38h05 | Departure days Tue, Fri | Cheapest price $152 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 01:05AM | Duration 36h20 | Departure days Sat | Cheapest price $163 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 04:35AM | Duration 35h00 | Departure days Thu | Cheapest price $197 |
Operator Greyhound | Departure Time 09:55PM | Arrival Time 05:10PM | Duration 42h15 | Departure days Tue, Fri | Cheapest price $151 |
The table below shows live departures for San Antonio, TX to Columbus, OH buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ + FlixBus · FlixBus | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 42h15 | 5:10 PM Columbus, E Town St (Bus Station), OH | 3 transfers | |
FlixBus+ · | 9:55 PM San Antonio, N St Mary's St (Greyhound), TX | 32h50 | 7:45 AM Columbus, E Mound St (Akili Christian High School), OH | 2 transfers | |
| Wednesday, August 5 | |||||
![]() | 11:50 AM San Antonio, TX | 37h00 | 12:50 AM Columbus, OH | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Find answers to the most common questions about traveling from San Antonio, TX to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most San Antonio, TX to Columbus, OH buses use the San Antonio, N St Mary's St (Greyhound) to Columbus, E Mound St (Akili Christian High School) station pair, with some services arriving at Columbus, E Town St (Bus Station). Use this guide to compare San Antonio, TX and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
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