San Luis Obispo, CA to Santa Ana, CA bus with FlixBus

Fri, Feb 06
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The cheapest and fastest buses from San Luis Obispo, CA to Santa Ana, CA

Showing times and prices for Feb 06

Cheapest price

$129

Average price

$129

Fastest journey

15 h 25 m

Average duration

15 h 25 m

Buses per day

1

Distance

308 km

Cheap tickets

The best way to find a cheap bus ticket from San Luis Obispo, CA to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Luis Obispo, CA to Santa Ana, CA will cost around $129 if you buy it on the day, but the cheapest tickets can be found for only $129.

Fast buses

It's difficult to get from San Luis Obispo, CA to Santa Ana, CA without transferring at least once.

Flixbus USA
04:10PM15h25
San Luis Obispo, CA
07:35AMSanta Ana, CA
$1291One-way
1 transfer

Travel Information

Compare train and bus for San Luis Obispo, CA to Santa Ana, CA

Omio recommends booking the train as it is the most popular option from San Luis Obispo, CA to Santa Ana, CA among Omio's users. If you are prioritising price take the train with prices starting from €42. For those with little time consider booking a train which can get you there in 6h 50m. The ticket price range depends on the travel mode: a train costs an average of €42, and a bus costs an average of €20.

Distance: 191 miles (308 km)

Compare bus with

Bus
Most popular
Train

€43

Average price

€42

Average price

Cheapest

9h 31m

Average total duration

9h 1m

Onboard

+

30m

Additional time*

7h 20m

Average total duration

Fastest

6h 50m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Live departures

San Luis Obispo, CA to Santa Ana, CA bus times

The table below shows live departures for San Luis Obispo, CA to Santa Ana, CA buses for today, Thursday, February 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:26 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus8:20 PM San Luis Obispo, CA
8h40
5:00 AM Santa Ana, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Luis Obispo, CA to Santa Ana, CA by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Feb 06
Sat
Feb 07
Sun
Feb 08
Mon
Feb 09
Tue
Feb 10
Wed
Feb 11
Thu
Feb 12

Why should you book San Luis Obispo, CA to Santa Ana, CA buses with Omio?

FlixBus operates all buses services from San Luis Obispo, CA to Santa Ana, CA.
Omio is an official ticket reseller for all your travel options from San Luis Obispo, CA to Santa Ana, CA.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of to find the best option for your trip from San Luis Obispo, CA to Santa Ana, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from San Luis Obispo, CA to Santa Ana, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from San Luis Obispo, CA to Santa Ana, CA.

Journey information

Overview: Bus from San Luis Obispo, CA to Santa Ana, CA

USAUSA
USAUSA
Icon of bus

Buses from San Luis Obispo, CA to Santa Ana, CA run on average 5 times per day, taking around 9h 1m. Cheap bus tickets for this journey start at $25 (€20) if you book in advance.

The earliest bus runs at 03:45, the last at 23:30. The fastest bus covers the 191 miles (308 km) distance in 8h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
191 miles (308 km)
Average bus duration
9h 1m
Cheapest ticket price
$25 (€20)
Buses per day
5
Fastest bus
8h 40m
First bus
03:45
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from San Luis Obispo, CA to Santa Ana, CAYou can travel by bus between San Luis Obispo, CA to Santa Ana, CA with FlixBus for as low as $25 (€20). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
8h 40m
Cheapest Price
$43 (€34)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from San Luis Obispo, CA to Santa Ana, CA

Find answers to the most common questions about traveling from San Luis Obispo, CA to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Luis Obispo, CA to Santa Ana, CA can start from as little as $25 (€20) when you book in advance. The average bus ticket price for San Luis Obispo, CA to Santa Ana, CA is $54 (€43) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Luis Obispo, CA to Santa Ana, CA is 8h 40m to travel the 191 miles (308 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Luis Obispo, CA to Santa Ana, CA leaves at 3:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Luis Obispo, CA to Santa Ana, CA leaves at 11:30 PM.
There are 5 buses a day from San Luis Obispo, CA to Santa Ana, CA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Luis Obispo, CA to Santa Ana, CA, you can count on FlixBus for the best way to get you to Santa Ana, CA. You can also check all possible bus companies who offer a service between San Luis Obispo, CA and Santa Ana, CA and compare the amenities they offer before buying a bus ticket.
A trip to Santa Ana, CA from San Luis Obispo, CA is worth doing but not as a day trip with a journey time of 8h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Luis Obispo, CA to Santa Ana, CA is September.
It's helpful to compare your options as there are 2 ways to travel between San Luis Obispo, CA and Santa Ana, CA including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from San Luis Obispo, CA to Santa Ana, CA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Luis Obispo, CA to Santa Ana, CA for bus company FlixBus.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from San Luis Obispo, CA to Santa Ana, CA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Luis Obispo, CA to Santa Ana, CA.
Yes, the following luggage options are included when booking a bus ticket from San Luis Obispo, CA to Santa Ana, CA:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Luis Obispo, CA to Santa Ana, CA:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Luis Obispo, CA to Santa Ana, CA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from San Luis Obispo, CA to Santa Ana, CA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from San Luis Obispo, CA to Santa Ana, CA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from San Luis Obispo, CA to Santa Ana, CA with the following bus company: FlixBus.

popular bus stations

Popular bus stations from San Luis Obispo, CA to Santa Ana, CA

San Luis Obispo
Santa Ana
The major bus station for departures in San Luis Obispo is San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum). Find all the information you need to know about services, amenities and connections at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) for your trip from San Luis Obispo to Santa Ana.
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum)
information

Most popular buses to and from Santa Ana, CA and San Luis Obispo, CA

HomeBusesBuses in USABus tickets to Santa Ana, CASan Luis Obispo, CA to Santa Ana, CA bus

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