San Luis Obispo, CA to Santa Clara, CA bus with Amtrak

Sat, Nov 22
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1,000+ travel companies
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Travel Information

Compare bus, train, and flight for San Luis Obispo, CA to Santa Clara, CA

Omio recommends booking the bus as it is the most popular option from San Luis Obispo, CA to Santa Clara, CA among Omio's users. If you are prioritising price take the bus with prices starting from €58. For those with little time consider booking a bus which can get you there in 4h 8m. The ticket price range depends on the travel mode: a bus costs an average of €58, and a train costs an average of €90.

Distance: 160 miles (258 km)

Compare bus with

Most popular
Bus
Train

€58

Average price

Cheapest

€90

Average price

4h 38m

Average total duration

Fastest

4h 8m

Onboard

+

30m

Additional time*

12h 49m

Average total duration

12h 19m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Live departures

San Luis Obispo, CA to Santa Clara, CA bus times

The table below shows live departures for San Luis Obispo, CA to Santa Clara, CA buses for today, Monday, November 24. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:18 AM
ProviderDepartsDurationArrivesTransfers
Tickets
amtrak5:15 PM San Luis Obispo, CA
4h45
10:00 PM Santa Clara, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Luis Obispo, CA to Santa Clara, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from San Luis Obispo, CA to Santa Clara, CA

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Buses from San Luis Obispo, CA to Santa Clara, CA run on average 7 times per day, taking around 4h 8m. Cheap bus tickets for this journey start at $71 (€58) if you book in advance.

The earliest bus runs at 00:30, the last at 14:48. The fastest bus covers the 160 miles (258 km) distance in 4h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
160 miles (258 km)
Average bus duration
4h 8m
Cheapest ticket price
$71 (€58)
Buses per day
7
Fastest bus
4h 45m
First bus
00:30
Last bus
14:48
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Amtrak from San Luis Obispo, CA to Santa Clara, CAYou can travel by bus between San Luis Obispo, CA to Santa Clara, CA with Amtrak for as low as $71 (€58). When you search for schedules and tickets, Omio will show you the best journey

Amtrak

About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
4h 45m
Cheapest Price
$71 (€58)
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the bus
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone

FAQs: Bus from San Luis Obispo, CA to Santa Clara, CA

Find answers to the most common questions about traveling from San Luis Obispo, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Luis Obispo, CA to Santa Clara, CA can start from as little as $78 (€64) when you book in advance. The average bus ticket price for San Luis Obispo, CA to Santa Clara, CA is $81 (€66); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Luis Obispo, CA to Santa Clara, CA is 4 h 45 min   to travel the 159 mile (257 km) long journey, with around there are 6 buses per day. Journey times can vary on weekends and holidays.
The first bus from San Luis Obispo, CA to Santa Clara, CA leaves at 12: 30AM. Plan your trip with the Journey Planner   from Omio.
The last bus from San Luis Obispo, CA to Santa Clara, CA leaves at 3: 20PM.
There are 6 buses a day from San Luis Obispo, CA to Santa Clara, CA which require at least one change with Amtrak. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Luis Obispo, CA to Santa Clara, CA, you can count on Amtrak for the best way to get you to Santa Clara, CA. You can also check all possible bus providers who offer a service from San Luis Obispo, CA to Santa Clara, CA and compare the amenities they offer before buying a bus ticket.
A trip to Santa Clara, CA from San Luis Obispo, CA is worth doing but not as a day trip with a journey time of 4 h 45 min each way. Check with Omio app   the best way to travel.
The cheapest month to travel from San Luis Obispo, CA to Santa Clara, CA by bus is September.
It's helpful to compare your options as there are 2 ways to travel between San Luis Obispo, CA and Santa Clara, CA including taking a bus or train.
No, the bus from San Luis Obispo, CA to Santa Clara, CA has no accessibility options.
No, there are no bathrooms on board the bus from San Luis Obispo, CA to Santa Clara, CA.
No, bikes are not allowed on board the bus from San Luis Obispo, CA to Santa Clara, CA.

To find the cheapest bus tickets for your trip from San Luis Obispo, CA to Santa Clara, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from San Luis Obispo, CA to Santa Clara, CA.
    No, luggage for the bus from San Luis Obispo, CA to Santa Clara, CA needs to be booked in addition.
    No, there are no additional luggage options for the bus from San Luis Obispo, CA to Santa Clara, CA.
    Unfortunately, pets are not allowed on the bus from San Luis Obispo, CA to Santa Clara, CA.
    No, there are no USB plugs on board the bus from San Luis Obispo, CA to Santa Clara, CA.
    No, there is no WiFi on board the bus from San Luis Obispo, CA to Santa Clara, CA.

    popular bus stations

    Popular bus stations from San Luis Obispo, CA to Santa Clara, CA

    San Luis Obispo
    Santa Clara
    San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum)
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