San Luis Obispo, CA to Santa Clara, CA bus

Sun, May 31
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from San Luis Obispo, CA to Santa Clara, CA

Showing times and prices for May 31

Cheapest price

$71

Average price

$71

Fastest journey

4 h 27 m

Average duration

4 h 27 m

Buses per day

1

Distance

258 km

Cheap tickets

The best way to find a cheap bus ticket from San Luis Obispo, CA to Santa Clara, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Luis Obispo, CA to Santa Clara, CA will cost around $71 if you buy it on the day, but the cheapest tickets can be found for only $71.

Fast buses

Of the 1 buses that leave San Luis Obispo, CA for Santa Clara, CA on Sun, May 31, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sun, May 31 the direct buses cover the 258 km distance in an average of 4 h 27 m but if you time it right, some buses will get you there in just 4 h 27 m .

On Sun, May 31 the slowest buses will take 4 h 27 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Amtrak
    8:30 PM4h27
    San Luis Obispo, CA
    12:57 AMSanta Clara, CA
    $711One-way
    0 transfers

Travel Information

Compare bus and train for San Luis Obispo, CA to Santa Clara, CA

Omio recommends booking the train as it is the most popular option from San Luis Obispo, CA to Santa Clara, CA among Omio's users. If you are prioritising price take the bus with prices starting from $71. For those with little time consider booking a bus which can get you there in 4h 8m. The ticket price range depends on the travel mode: a bus costs an average of $71, and a train costs an average of $113.

Distance: 160 miles (258 km)

Compare bus with

Bus
Most popular
Train
Driving

$73

Average price

Cheapest

$142

Average price

$39

Average price

(fuel + tolls)

4h 38m

Average total duration

Fastest

4h 8m

Onboard

+

30m

Additional time*

10h 11m

Average total duration

9h 41m

Onboard

+

30m

Additional time*

2h 56m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from San Luis Obispo, CA to Santa Clara, CA is a bus with an average price of $73 (€58).

This is compared to other travel options from San Luis Obispo, CA to Santa Clara, CA:

A bus is $69 (€56) less than a train for this route with tickets for a train from San Luis Obispo, CA to Santa Clara, CA costing on average $142 (€114).

The fastest way to travel from San Luis Obispo, CA to Santa Clara, CA is by bus with an average journey time of 4h 8m.

Other travel options to Santa Clara, CA take longer:

Train takes on average 9h 41m.

It's helpful to compare your options as there are 2 ways to travel between San Luis Obispo, CA and Santa Clara, CA including taking a bus and train.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

San Luis Obispo, CA to Santa Clara, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Amtrak
Departure Time
07:40AM
Arrival Time
01:24PM
Duration
5h44
Departure days
Tue, Thu, Fri
Cheapest price
$71
Operator
Amtrak
Departure Time
08:30PM
Arrival Time
12:57AM
Duration
4h27
Departure days
Sun
Cheapest price
$71

Compare prices and tickets San Luis Obispo, CA to Santa Clara, CA by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
May 31
Mon
Jun 01
Tue
Jun 02
Wed
Jun 03
Thu
Jun 04
Fri
Jun 05
Sat
Jun 06

Journey information

Overview: Bus from San Luis Obispo, CA to Santa Clara, CA

USAUSA
USAUSA
Icon of bus

Buses from San Luis Obispo, CA to Santa Clara, CA run on average 8 times per day, taking around 4h 8m. Cheap bus tickets for this journey start at $71 (€57) if you book in advance.

The earliest bus runs at 00:30, the last at 14:55. The fastest bus covers the 160 miles (258 km) distance in 4h 27m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
160 miles (258 km)
Average bus duration
4h 8m
Cheapest ticket price
$71 (€57)
Buses per day
8
Fastest bus
4h 27m
First bus
12:30 AM
Last bus
2:55 PM
Cheapest Month
Jun
Cheapest Day
Sun
High Season
Jan - Mar
Low Season
Jul - Sep
Best time to book
70 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from San Luis Obispo, CA to Santa Clara, CA

Find answers to the most common questions about traveling from San Luis Obispo, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Luis Obispo, CA to Santa Clara, CA can start from as little as $71 (€57) when you book in advance. The average bus ticket price for San Luis Obispo, CA to Santa Clara, CA is $73 (€58) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Luis Obispo, CA to Santa Clara, CA is 4h 27m to travel the 160 miles (258 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Luis Obispo, CA to Santa Clara, CA leaves at 12:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Luis Obispo, CA to Santa Clara, CA leaves at 2:55 PM.
A trip to Santa Clara, CA from San Luis Obispo, CA is worth doing but not as a day trip with a journey time of 4h 27m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Luis Obispo, CA to Santa Clara, CA is June.
It's helpful to compare your options as there are 2 ways to travel between San Luis Obispo, CA and Santa Clara, CA including taking a bus and train.
No, there are no bathrooms on board the bus from San Luis Obispo, CA to Santa Clara, CA.
No, the bus from San Luis Obispo, CA to Santa Clara, CA has no accessibility options.
No, bikes are not allowed on board the bus from San Luis Obispo, CA to Santa Clara, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from San Luis Obispo, CA to Santa Clara, CA.
No, luggage for the bus from San Luis Obispo, CA to Santa Clara, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from San Luis Obispo, CA to Santa Clara, CA.
Unfortunately, pets are not allowed on the bus from San Luis Obispo, CA to Santa Clara, CA.
No, there are no USB plugs on board the bus from San Luis Obispo, CA to Santa Clara, CA.
No, there is no WiFi on board the bus from San Luis Obispo, CA to Santa Clara, CA.
Since neither San Luis Obispo, CA nor Santa Clara, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Santa Clara, CA, travelers should be cautious of pickpocketing in crowded areas and be aware of occasional vehicle break-ins, especially in parking lots near popular attractions. Common scams include overcharging by unauthorized taxi or ride-share drivers and fake ticket sellers near event venues. It's advisable to use official transportation services and remain vigilant in busy public spaces.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from San Luis Obispo, CA to Santa Clara, CA

San Luis Obispo
Santa Clara
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum)
information

More options for your journey from San Luis Obispo, CA to Santa Clara, CA

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Santa Clara, CASan Luis Obispo, CA to Santa Clara, CA bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone