San Luis Obispo, CA to Santa Clara, CA bus

Wed, Oct 14
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FlixBus
Alsa
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Rede Expressos
Avanza
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Avanza
2,000+ travel companies
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Journey information

Overview: Bus from San Luis Obispo, CA to Santa Clara, CA

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Take a bus from San Luis Obispo, CA to Santa Clara, CA and enjoy the approximately 160 miles (258 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:30, the last at 14:55.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
160 miles (258 km)
First bus
12:30 AM
Last bus
2:55 PM
Cheapest Month
Feb
Cheapest Day
Sun
High Season
Apr - Jun
Low Season
Jul - Sep
Best time to book
7 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

San Luis Obispo, CA to Santa Clara, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Amtrak
Departure Time
07:40AM
Arrival Time
01:24PM
Duration
5h44
Departure days
Tue, Thu, Fri
Cheapest price
$68
Operator
Amtrak
Departure Time
08:30PM
Arrival Time
12:57AM
Duration
4h27
Departure days
Sun
Cheapest price
$68

Complete guide to Santa Clara, CA

Things to do in Santa Clara, CA

Discover the best of Santa Clara, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santa Clara, CA trip today.

  • Recommended

Intel Museum

Interactive museum tracing Intel’s chipmaking history and computing advances through exhibits, artifacts, and hands-on displays.

  • Recommended

de Saisset Museum

Art museum on Santa Clara University’s campus showing rotating exhibitions of modern and historical works in an intimate setting.

  • Recommended

Harris-Lass Historic Museum

Local history museum in a restored farmhouse featuring Santa Clara artifacts, period furnishings, and changing community exhibits.

United States dollar ($)

Santa Clara is costly for visitors, with high hotel rates and dining prices driven by Silicon Valley demand. Transit is limited, so rideshares or car hire can add to daily costs.

Average meal costs

Budget
$12-18 for fast food or casual takeout.
Mid-range
$25-45 per person for a restaurant meal.
Fine dining
$70+ per person for upscale dining.
Coffee
$4-6 for a coffee or cappuccino.

Tipping culture

Tip 15-20% at restaurants, 10-15% for taxis or rideshares, and $1-2 for coffee drinks or café service if there is table service.

FAQs: Bus from San Luis Obispo, CA to Santa Clara, CA

Find answers to the most common questions about traveling from San Luis Obispo, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from San Luis Obispo, CA to Santa Clara, CA leaves at 12:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Luis Obispo, CA to Santa Clara, CA leaves at 2:55 PM.
Yes, you can take a between San Luis Obispo, CA and Santa Clara, CA.
No, the bus from San Luis Obispo, CA to Santa Clara, CA has no accessibility options.
No, there are no bathrooms on board the bus from San Luis Obispo, CA to Santa Clara, CA.
No, bikes are not allowed on board the bus from San Luis Obispo, CA to Santa Clara, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from San Luis Obispo, CA to Santa Clara, CA.
No, luggage for the bus from San Luis Obispo, CA to Santa Clara, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from San Luis Obispo, CA to Santa Clara, CA.
Unfortunately, pets are not allowed on the bus from San Luis Obispo, CA to Santa Clara, CA.
No, there are no USB plugs on board the bus from San Luis Obispo, CA to Santa Clara, CA.
No, there is no WiFi on board the bus from San Luis Obispo, CA to Santa Clara, CA.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Santa Clara, CA, travelers should be cautious of pickpocketing in crowded areas and be aware of occasional vehicle break-ins, especially in parking lots near popular attractions. Common scams include overcharging by unauthorized taxi or ride-share drivers and fake ticket sellers near event venues. It's advisable to use official transportation services and remain vigilant in busy public spaces.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

More options for your journey from San Luis Obispo, CA to Santa Clara, CA

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Most popular bus connections to Santa Clara, CA

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