- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
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The cheapest and fastest buses from San Luis Obispo, CA to San Diego, CA
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- €49
- Average ticket price on Nov 03
- €52
- Fastest journey on Nov 03
- 10 h 15 m
- Average journey duration on Nov 03
- 10 h 57 m
- Buses on Nov 03
- 3
- Distance
- 431 km
Cheap tickets
The best way to find a cheap bus ticket from San Luis Obispo, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Luis Obispo, CA to San Diego, CA will cost around €52 if you buy it on the day, but the cheapest tickets can be found for only €49.
Fast buses
It's difficult to get from San Luis Obispo, CA to San Diego, CA without transferring at least once.
FlixBus · FlixBus12:00 PM 10h15 San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA €49 1 One-way 1 transfer- FlixBus+
12:00 PM 11h50 San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA 11:50 PM San Diego, Congress Street (Old Town Park), CA €50 1 One-way 1 transfer - FlixBus · FlixBus
12:00 PM 10h45 San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA 10:45 PM San Diego, San Ysidro Transit Center €57 1 One-way 1 transfer
- FlixBus · FlixBus
12:00 PM 10h15 San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA €49 1 One-way 1 transfer - FlixBus · FlixBus
12:00 PM 10h45 San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA 10:45 PM San Diego, San Ysidro Transit Center €57 1 One-way 1 transfer - FlixBus+
12:00 PM 11h50 San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA 11:50 PM San Diego, Congress Street (Old Town Park), CA €50 1 One-way 1 transfer
Journey information
Overview: Bus from San Luis Obispo, CA to San Diego, CA
USAUSA
Buses from San Luis Obispo, CA to San Diego, CA run on average 3 times per day, taking around 8h 3m. Cheap bus tickets for this journey start at €27 if you book in advance.
The earliest bus runs at 03:45, the last at 21:25. The fastest bus covers the 267 miles (431 km) distance in 7h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 267 miles (431 km) |
Average bus duration 8h 3m |
Cheapest ticket price €27 |
Buses per day 3 |
Fastest bus 7h 40m |
First bus 3:45 AM |
Last bus 9:25 PM |
Cheapest Month Jan |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sat |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your San Luis Obispo, CA to San Diego, CA trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from San Luis Obispo, CA to San Diego, CA.
Cheap bus tickets from San Luis Obispo, CA to San Diego, CA can start from as little as €27 when you book in advance. The average bus ticket price for San Luis Obispo, CA to San Diego, CA is €51 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from San Luis Obispo, CA to San Diego, CA leaves at 3:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Luis Obispo, CA to San Diego, CA leaves at 9:25 PM.
There are 3 buses a day from San Luis Obispo, CA to San Diego, CA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
San Luis Obispo, CA to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 10:45AM | Arrival Time 07:07PM | Duration 8h22 | Departure days Thu | Cheapest price €154 |
Operator Amtrak | Departure Time 11:30AM | Arrival Time 06:52PM | Duration 7h22 | Departure days Thu, Fri | Cheapest price €148 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 10:45PM | Duration 10h45 | Departure days Mon, Tue, Wed, Thu | Cheapest price €39 |
Live departures
San Luis Obispo, CA to San Diego, CA bus times
The table below shows live departures for San Luis Obispo, CA to San Diego, CA buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 12:00 PM San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA | 10h45 | 10:45 PM San Diego, San Ysidro Transit Center | 1 transfer | |
| FlixBus · FlixBus | 12:00 PM San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA | 10h15 | 10:15 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 1 transfer | |
| FlixBus+ | 12:00 PM San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA | 11h50 | 11:50 PM San Diego, Congress Street (Old Town Park), CA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book San Luis Obispo, CA to San Diego, CA buses with Omio?
FlixBus operates all buses services from San Luis Obispo, CA to San Diego, CA.
Omio is an official ticket reseller for all your travel options from San Luis Obispo, CA to San Diego, CA.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Luis Obispo, CA to San Diego, CA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Luis Obispo, CA to San Diego, CA.
Bus providers: FlixBus from San Luis Obispo, CA to San Diego, CAYou can travel by bus between San Luis Obispo, CA to San Diego, CA with FlixBus for as low as €27. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
7h 40m
Cheapest FlixBus Price
€27
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Companies, tickets, and onboard amenities between San Luis Obispo, CA and San Diego, CA
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from San Luis Obispo, CA to San Diego, CA, you can count on FlixBus for the best way to get you to San Diego, CA. You can also check all possible bus companies who offer a service between San Luis Obispo, CA and San Diego, CA and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from San Luis Obispo, CA to San Diego, CA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Luis Obispo, CA to San Diego, CA for bus company FlixBus.
Whether you can cancel your bus ticket from San Luis Obispo, CA to San Diego, CA depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from San Luis Obispo, CA to San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from San Luis Obispo, CA to San Diego, CA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Luis Obispo, CA to San Diego, CA:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Luis Obispo, CA to San Diego, CA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from San Luis Obispo, CA to San Diego, CA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from San Luis Obispo, CA to San Diego, CA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from San Luis Obispo, CA to San Diego, CA with the following bus company: FlixBus.
Complete guide to San Diego, CA
Things to do in San Diego, CA
Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.
- Must visit
Museum of Contemporary Art San Diego
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
- Must visit
USS Midway Museum
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
- Must visit
Balboa Park
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
- Must visit
Gaslamp Quarter
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
- Must visit
La Jolla Cove
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
Fish Taco
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
California Burrito
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
- Gluten-free
Sea Urchin (Uni)
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Sushi Ota
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Mitch's Seafood
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Juniper and Ivy
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
US Dollar ($)
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a mid-range meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
Plan your visit to San Diego, CA
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Diego, CA.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from San Luis Obispo, CA to San Diego, CA
Find answers to the most common questions about traveling from San Luis Obispo, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between San Luis Obispo, CA and San Diego, CA including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from San Luis Obispo, CA to San Diego, CA
Most San Luis Obispo, CA to San Diego, CA buses use the San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) to San Diego, West Harbor Drive (The Headquarters at Seaport District) station pair, with some services arriving at San Diego, Congress Street (Old Town Park). Use this guide to compare San Luis Obispo, CA and San Diego, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in San Luis Obispo
Arrival bus stations in San Diego
Which San Luis Obispo, CA station do buses to San Diego, CA leave from?
Buses from San Luis Obispo, CA to San Diego, CA leave from San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum). The station is 0 miles (1 km) from San Luis Obispo, CA city centre at 1940 Santa Barbara Ave, San Luis Obispo, CA 93401, USA.
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum)1940 Santa Barbara Ave, San Luis Obispo, CA 93401, USA
City-centre transport
Getting to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) from San Luis Obispo city centre
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) is 1 km from San Luis Obispo city centre. Public transport options include:
Bus3A · 7m · €2 · every ~2 min
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) bus station facilities and services
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum). ATMs are available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum).
Tickets and information
Ticket office support is available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum).
Parking, taxis and toilets
Available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum): Basic accessibility features available.
Which San Diego, CA station do buses from San Luis Obispo, CA arrive at?
Buses from San Luis Obispo, CA to San Diego, CA most often arrive at San Diego, West Harbor Drive (The Headquarters at Seaport District). Some services arrive at San Diego, Congress Street (Old Town Park), so check your ticket before travel to confirm your San Diego, CA arrival station.
San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USA
City-centre transport
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
TRUE
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USA
City-centre transport
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 20m · €1
83 · 26m · €5
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USA
City-centre transport
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 25m · €2
910 · 41m · €5
TramBlue · 41m · €14 · every ~14 min
Blue · 43m · €14 · every ~14 min
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
Bus stations for San Luis Obispo, CA to San Diego, CA
Check bus stations information for San Luis Obispo, CA and San Diego, CA, including where buses depart and arrive on this route.
When departing from San Luis Obispo, CA , you have various bus station options to start your journey from including San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) . When arriving in San Diego, CA , you can end your journey in bus stations like San Diego, West Harbor Drive (The Headquarters at Seaport District), San Diego, Congress Street (Old Town Park), San Diego, San Ysidro Transit Center .Passengers board the bus most frequently from San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at San Diego, West Harbor Drive (The Headquarters at Seaport District), located 1 away from the city centre.
Most popular bus connections from San Luis Obispo, CA
More options for your journey from San Luis Obispo, CA to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and San Luis Obispo, CA
Most popular bus connections to San Diego, CA
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