The cheapest and fastest buses from San Luis Obispo, CA to San Diego, CA
Cheapest price
$75
Average price
$76
Fastest journey
8 h 40 m
Average duration
9 h 48 m
Buses per day
2
Distance
431 km
The best way to find a cheap bus ticket from San Luis Obispo, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Luis Obispo, CA to San Diego, CA will cost around $76 if you buy it on the day, but the cheapest tickets can be found for only $75.
Of the 2 buses that leave San Luis Obispo, CA for San Diego, CA on Mon, Dec 22, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 22 the direct buses cover the 431 km distance in an average of 9 h 48 m but if you time it right, some buses will get you there in just 8 h 40 m .
On Mon, Dec 22 the slowest buses will take 10 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for San Luis Obispo, CA to San Diego, CA
Omio recommends booking the train as it is the most popular option from San Luis Obispo, CA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €24. For those with little time consider booking a flight which can get you there in 1h 15m. The ticket price range depends on the travel mode: a bus costs an average of €24, and a flight costs an average of €85.
Distance: 267 miles (431 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€50 Average price Cheapest | €57 Average price | €242 Average price |
8h 25m Average total duration 7h 55m Onboard + 30m Additional time* | 9h 20m Average total duration 8h 50m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 1h 15m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
San Luis Obispo, CA to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:55PM | Arrival Time 10:15PM | Duration 9h20 | Departure days Tue | Cheapest price $107 |
Live departures
San Luis Obispo, CA to San Diego, CA bus times
The table below shows live departures for San Luis Obispo, CA to San Diego, CA buses for today, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:00 PM San Luis Obispo, CA | 9h50 | 6:50 AM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Luis Obispo, CA to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 22
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Dec 28
Journey information
Overview: Bus from San Luis Obispo, CA to San Diego, CA
Buses from San Luis Obispo, CA to San Diego, CA run on average 11 times per day, taking around 7h 55m. Cheap bus tickets for this journey start at $31 (€24) if you book in advance.
The earliest bus runs at 03:45, the last at 21:25. The fastest bus covers the 267 miles (431 km) distance in 8h 10m.
Distance 267 miles (431 km) |
Average bus duration 7h 55m |
Cheapest ticket price $31 (€24) |
Buses per day 11 |
Fastest bus 8h 10m |
First bus 03:45 |
Last bus 21:25 |
FAQs: Bus from San Luis Obispo, CA to San Diego, CA
Find answers to the most common questions about traveling from San Luis Obispo, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- Enjoy a harbor cruise for stunning views of the skyline and naval ships
- Hike the scenic trails at Torrey Pines State Natural Reserve
- Visit the Birch Aquarium to learn about marine life and ocean conservation
- Experience the thrill of a whale watching tour off the coast.
To find the cheapest bus tickets for your trip from San Luis Obispo, CA to San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
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Popular bus stations from San Luis Obispo, CA to San Diego, CA
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