Why should you book San Luis Obispo, CA to Santa Maria, CA buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from San Luis Obispo, CA to Santa Maria, CA
Take a bus from San Luis Obispo, CA to Santa Maria, CA and enjoy the approximately 26 miles (42 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
There are 2 buses per day. The earliest bus runs at 07:30, the last at 19:25.
Distance 26 miles (42 km) |
Average bus duration 48m |
Buses per day 2 |
Direct buses 2 |
First bus 7:30 AM |
Last bus 7:25 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Bus providers: FlixBus from San Luis Obispo, CA to Santa Maria, CAYou can travel by bus between San Luis Obispo, CA to Santa Maria, CA with FlixBus. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from San Luis Obispo, CA to Santa Maria, CA
Find answers to the most common questions about traveling from San Luis Obispo, CA to Santa Maria, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Maria, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from San Luis Obispo, CA to Santa Maria, CA
Most San Luis Obispo, CA to Santa Maria, CA buses use the San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) to Santa Maria, Nicholson Avenue / Cypress Street station pair. Use this guide to compare San Luis Obispo, CA and Santa Maria, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) from San Luis Obispo city centre
Getting to Santa Maria, Nicholson Avenue / Cypress Street from Santa Maria city centre
Most popular bus connections from San Luis Obispo, CA
More options for your journey from San Luis Obispo, CA to Santa Maria, CA
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