- Must visit
San Francisco Museum of Modern Art
Major modern and contemporary art museum with an internationally important collection and frequent blockbuster exhibitions.
Cheapest price
$106
Average price
$115
Fastest journey
4 h 45 m
Average duration
6 h 8 m
Buses per day
5
Distance
319 km
The best way to find a cheap bus ticket from San Luis Obispo, CA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Luis Obispo, CA to San Francisco, CA will cost around $115 if you buy it on the day, but the cheapest tickets can be found for only $106.
Of the 5 buses that leave San Luis Obispo, CA for San Francisco, CA on Sun, Jul 12, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jul 12 the direct buses cover the 319 km distance in an average of 6 h 8 m but if you time it right, some buses will get you there in just 4 h 45 m .
On Sun, Jul 12 the slowest buses will take 6 h 49 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
4761 AMTRAK · 746 Capitol Corridor
4765 AMTRAK · 748 Capitol Corridor
4761 AMTRAK · 744 Capitol Corridor
4765 AMTRAK · 14 Coast Starlight
FlixBus
4761 AMTRAK · 744 Capitol Corridor
4765 AMTRAK · 748 Capitol Corridor
4765 AMTRAK · 14 Coast Starlight
4761 AMTRAK · 746 Capitol CorridorOmio recommends booking the bus as it is the most popular option from San Luis Obispo, CA to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a flight which can get you there in 1h 41m. The ticket price range depends on the travel mode: a bus costs an average of $38, and a flight costs an average of $244.
Distance: 198 miles (319 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$67 Average price Cheapest | $74 Average price | $402 Average price | $47 Average price (fuel + tolls) |
5h 37m Average total duration 5h 7m Onboard + 30m Additional time* | 7h 19m Average total duration 6h 49m Onboard + 30m Additional time* | 4h 41m Average total duration Fastest 1h 41m Onboard + 3h 0m Additional time* | 3h 38m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Luis Obispo, CA to San Francisco, CA:
A bus is $7 (€6) less than a train for this route with tickets for a train from San Luis Obispo, CA to San Francisco, CA costing on average $74 (€61).
A bus is $336 (€276) less than a flight for this route with tickets for a flight from San Luis Obispo, CA to San Francisco, CA costing on average $402 (€331).
Other travel options to San Francisco, CA take longer:
Bus takes on average 5h 7m.
Train takes on average 6h 49m.
You'll arrive about -2h -29m sooner (5h 7m by bus vs 3h 38m by car) and save roughly $-19.32 (€-15.89) compared to fuel and tolls ($67 (€55) vs $47 (€39)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 10:05AM | Arrival Time 04:11PM | Duration 6h06 | Departure days Fri | Cheapest price $112 |
Operator Amtrak | Departure Time 12:20PM | Arrival Time 07:09PM | Duration 6h49 | Departure days Fri, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 05:50PM | Duration 4h45 | Departure days Mon, Tue, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 01:20PM | Arrival Time 05:55PM | Duration 4h35 | Departure days Wed | Cheapest price $46 |
Operator Amtrak | Departure Time 02:45PM | Arrival Time 09:19PM | Duration 6h34 | Departure days Fri, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 08:20PM | Duration 4h15 | Departure days Thu, Sat | Cheapest price $43 |
The table below shows live departures for San Luis Obispo, CA to San Francisco, CA buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 4:05 PM San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA | 4h15 | 8:20 PM San Francisco, Townsend Street / 5th Street, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from San Luis Obispo, CA to San Francisco, CA run on average 4 times per day, taking around 5h 7m. Cheap bus tickets for this journey start at $38 (€31) if you book in advance.
There are 1 buses per day. The earliest bus runs at 06:11, the last at 16:10. The fastest bus covers the 198 miles (319 km) distance in 4h 15m.
Distance 198 miles (319 km) |
Average bus duration 5h 7m |
Cheapest ticket price $38 (€31) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 4h 15m |
First bus 6:11 AM |
Last bus 4:10 PM |
Cheapest Month Apr |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 56 days |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Major modern and contemporary art museum with an internationally important collection and frequent blockbuster exhibitions.
Hands-on science and art museum on the Embarcadero, especially popular for interactive exhibits and bay views.
Leading fine arts museum in Golden Gate Park, known for American art, textiles, and its observation tower.
Busy waterfront district known for classic San Francisco atmosphere, bay views, piers, and easy access to major sights.
Famous crooked block with steep curves, manicured gardens, and one of the city's most photographed street scenes.
Huge urban park with gardens, lakes, museums, and broad walking and cycling routes across the western city.
A tomato-based seafood stew created by Italian American fishermen in San Francisco, typically filled with crab, clams, mussels, shrimp, and fish.
San Francisco’s famous tangy sourdough loaf, shaped by the city’s historic wild yeast culture and long baking tradition.
A large foil-wrapped burrito associated with the Mission District, usually packed with rice, beans, meat, salsa, and extras.
Classic San Francisco institution serving carved prime rib with old-fashioned hospitality and a lively, upscale supper-club feel.
Iconic Mission District taqueria celebrated for Mission-style burritos and tacos with a simple, always-busy casual atmosphere.
Historic seafood counter famous for ultra-fresh oysters, crab, and cioppino ingredients in a classic old-school San Francisco setting.
Prices are high for hotels, dining, parking, and taxes. Budget options exist, but overall costs rank among the highest in the US.
Tip 18-20% in restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15% or round up. Hotels: USD 2-5 for porters, USD 3-5 daily for housekeeping.
Find answers to the most common questions about traveling from San Luis Obispo, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

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