The cheapest and fastest buses from Houston, TX to Santa Ana, CA
Cheapest price
$131
Average price
$133
Fastest journey
1 d 11 h 30 m
Average duration
1 d 14 h 27 m
Buses per day
6
Distance
2169 km
The best way to find a cheap bus ticket from Houston, TX to Santa Ana, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Houston, TX to Santa Ana, CA will cost around $133 if you buy it on the day, but the cheapest tickets can be found for only $131.
It's difficult to get from Houston, TX to Santa Ana, CA without transferring at least 2 times.
FlixBus+
· 5:35 PM40h25Houston, Southwest Fwy (Shell), TX8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)$1311One-way2 transfers
· · +
6:35 AM51h25Houston, Southwest Fwy (Chevron), TX8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)$1311One-way3 transfers
FlixBus+
· 6:00 PM40h00Houston, Gray St Parking (Bus Station), TX8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)$1331One-way2 transfers
· · 6:55 PM39h05Houston, Harrisburg Blvd (Greyhound Bus Station), TX8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)$1331One-way2 transfers
· · 2:00 AM35h30Houston, Harrisburg Blvd (Greyhound Bus Station), TX11:30 AMSanta Ana, E Santa Ana Blvd (Train Station)$1361One-way2 transfers
· · 2:00 AM35h30Houston, Harrisburg Blvd (Greyhound Bus Station), TX11:30 AMSanta Ana, E Santa Ana Blvd (Train Station)$1361One-way2 transfers
· · 8:15 AM37h15Houston, Harrisburg Blvd (Greyhound Bus Station), TX7:30 PMSanta Ana, E Santa Ana Blvd (Train Station)$1361One-way2 transfers
· · 6:55 PM39h05Houston, Harrisburg Blvd (Greyhound Bus Station), TX8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)$1331One-way2 transfers
FlixBus+
· 6:00 PM40h00Houston, Gray St Parking (Bus Station), TX8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)$1331One-way2 transfers
FlixBus+
· 5:35 PM40h25Houston, Southwest Fwy (Shell), TX8:00 AMSanta Ana, E Santa Ana Blvd (Train Station)$1311One-way2 transfers
Travel Information
Compare train, bus, and flight for Houston, TX to Santa Ana, CA
Omio recommends booking the flight as it is the most popular option from Houston, TX to Santa Ana, CA among Omio's users. If you are prioritising price take the bus with prices starting from $131. For those with little time consider booking a flight which can get you there in 8h 49m. The ticket price range depends on the travel mode: a bus costs an average of $131, and a flight costs an average of $145.
Distance: 1347 miles (2169 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$204 Average price Cheapest | $358 Average price | $280 Average price |
38h 34m Average total duration 38h 4m Onboard + 30m Additional time* | 11h 49m Average total duration Fastest 8h 49m Onboard + 3h 0m Additional time* | 39h 35m Average total duration 39h 5m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Houston, TX to Santa Ana, CA:
A bus is $76 (€61) less than a train for this route with tickets for a train from Houston, TX to Santa Ana, CA costing on average $280 (€226).
A bus is $154 (€125) less than a flight for this route with tickets for a flight from Houston, TX to Santa Ana, CA costing on average $358 (€289).
Other travel options to Santa Ana, CA take longer:
Bus takes on average 38h 4m.
Train takes on average 39h 5m.
Houston, TX to Santa Ana, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 04:00PM | Duration 39h05 | Departure days Tue | Cheapest price $323 |
Operator Greyhound | Departure Time 02:00AM | Arrival Time 11:30AM | Duration 35h30 | Departure days Tue, Wed | Cheapest price $136 |
Operator Greyhound | Departure Time 06:35AM | Arrival Time 08:00AM | Duration 51h25 | Departure days Tue, Wed | Cheapest price $131 |
Operator Greyhound | Departure Time 08:15AM | Arrival Time 07:30PM | Duration 37h15 | Departure days Tue, Wed | Cheapest price $136 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 08:00AM | Duration 46h50 | Departure days Wed | Cheapest price $166 |
Operator Greyhound | Departure Time 11:25AM | Arrival Time 08:00AM | Duration 46h35 | Departure days Wed | Cheapest price $169 |
Operator Greyhound | Departure Time 01:15PM | Arrival Time 02:30AM | Duration 37h15 | Departure days Fri | Cheapest price $191 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 08:00AM | Duration 40h25 | Departure days Tue | Cheapest price $131 |
Operator Greyhound | Departure Time 06:00PM | Arrival Time 08:00AM | Duration 40h00 | Departure days Tue | Cheapest price $133 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 08:00AM | Duration 39h05 | Departure days Tue, Wed | Cheapest price $133 |
Live departures
Houston, TX to Santa Ana, CA bus times
The table below shows live departures for Houston, TX to Santa Ana, CA buses for today, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:55 AM Houston, TX | 39h05 | 4:00 PM Santa Ana, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Houston, TX to Santa Ana, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 19
May 20
May 21
May 22
May 23
May 24
May 25
Journey information
Overview: Bus from Houston, TX to Santa Ana, CA
Buses from Houston, TX to Santa Ana, CA run on average 6 times per day, taking around 38h 4m. Cheap bus tickets for this journey start at $131 (€105) if you book in advance.
The earliest bus runs at 02:00, the last at 21:40. The fastest bus covers the 1347 miles (2169 km) distance in 35h 30m.
Distance 1347 miles (2169 km) |
Average bus duration 38h 4m |
Cheapest ticket price $131 (€105) |
Buses per day 6 |
Fastest bus 35h 30m |
First bus 2:00 AM |
Last bus 9:40 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
FAQs: Bus from Houston, TX to Santa Ana, CA
Find answers to the most common questions about traveling from Houston, TX to Santa Ana, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Houston, TX to Santa Ana, CA
More options for your journey from Houston, TX to Santa Ana, CA
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