Santa Ana, CA to San Luis Obispo, CA bus

Fri, Dec 19
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FlixBus
Alsa
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Rede Expressos
Itabus
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
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Travel Information

Compare train and bus for Santa Ana, CA to San Luis Obispo, CA

Omio recommends booking the train as it is the most popular option from Santa Ana, CA to San Luis Obispo, CA among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a train which can get you there in 6h 29m. The ticket price range depends on the travel mode: a bus costs an average of €26, and a train costs an average of €42.

Distance: 191 miles (308 km)

Compare bus with

Bus
Most popular
Train

€37

Average price

Cheapest

€42

Average price

7h 18m

Average total duration

6h 48m

Onboard

+

30m

Additional time*

6h 59m

Average total duration

Fastest

6h 29m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Santa Ana, CA to San Luis Obispo, CA by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Santa Ana, CA to San Luis Obispo, CA

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Buses from Santa Ana, CA to San Luis Obispo, CA run on average 6 times per day, taking around 6h 48m. Cheap bus tickets for this journey start at $32 (€26) if you book in advance.

The earliest bus runs at 03:45, the last at 23:45. The fastest bus covers the 191 miles (308 km) distance in 6h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
191 miles (308 km)
Average bus duration
6h 48m
Cheapest ticket price
$32 (€26)
Buses per day
6
Fastest bus
6h 35m
First bus
03:45
Last bus
23:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Santa Ana, CA to San Luis Obispo, CA

Find answers to the most common questions about traveling from Santa Ana, CA to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Santa Ana, CA to San Luis Obispo, CA can start from as little as $39 (€31) when you book in advance. The average bus ticket price for Santa Ana, CA to San Luis Obispo, CA is $68 (€55); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Santa Ana, CA to San Luis Obispo, CA bus travel time is 6 h 50 min   for the 190 mile (307 km) long route, but the duration can vary if you travel on weekends and holidays.
The first bus from Santa Ana, CA to San Luis Obispo, CA leaves at 3: 45AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Santa Ana, CA to San Luis Obispo, CA leaves at 11: 30PM.
The cheapest month to travel from Santa Ana, CA to San Luis Obispo, CA by bus is September.
You have options as you can travel to San Luis Obispo, CA from Santa Ana, CA 2 different ways: train or bus.
No, the bus from Santa Ana, CA to San Luis Obispo, CA has no accessibility options.
No, there are no bathrooms on board the bus from Santa Ana, CA to San Luis Obispo, CA.
Some of the most interesting sights to explore in San Luis Obispo, CA are:
  • Bubblegum Alley, a narrow alleyway famous for its walls covered in layers of chewed gum left by visitors
  • Mission San Luis Obispo de Tolosa, a historic Spanish mission founded in 1772 with a museum and beautiful gardens
  • Bishop Peak, a popular hiking destination offering panoramic views of the city and surrounding landscapes
  • San Luis Obispo Museum of Art, a contemporary art museum showcasing works by regional and national artists
  • Avila Beach, a nearby coastal spot known for its sandy shores and scenic pier.
The best things to do in San Luis Obispo, CA include:
  • Stroll through Downtown SLO, a vibrant area with shops, restaurants, and the famous Thursday Night Farmers' Market
  • Attend a performance at the Fremont Theater, a historic venue known for its art deco architecture and live events
  • Visit the San Luis Obispo Children's Museum, offering interactive exhibits and activities for kids
  • Explore the local wineries and vineyards, enjoying tastings and tours in the Edna Valley wine region
  • Discover the natural beauty of Montana de Oro State Park, with its rugged cliffs, secluded beaches, and scenic hiking trails.
No, bikes are not allowed on board the bus from Santa Ana, CA to San Luis Obispo, CA.

To find the cheapest bus tickets for your trip from Santa Ana, CA to San Luis Obispo, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Santa Ana, CA to San Luis Obispo, CA.
    No, luggage for the bus from Santa Ana, CA to San Luis Obispo, CA needs to be booked in addition.
    No, there are no additional luggage options for the bus from Santa Ana, CA to San Luis Obispo, CA.
    Unfortunately, pets are not allowed on the bus from Santa Ana, CA to San Luis Obispo, CA.
    No, there are no USB plugs on board the bus from Santa Ana, CA to San Luis Obispo, CA.
    No, there is no WiFi on board the bus from Santa Ana, CA to San Luis Obispo, CA.

    popular bus stations

    Popular bus stations from Santa Ana, CA to San Luis Obispo, CA

    Santa Ana
    San Luis Obispo
    The major bus station for departures in Santa Ana is Santa Ana, E Santa Ana Blvd (Train Station). Find all the information you need to know about services, amenities and connections at Santa Ana, E Santa Ana Blvd (Train Station) for your trip from Santa Ana to San Luis Obispo.
    Santa Ana, E Santa Ana Blvd (Train Station)
    information

    Most popular buses to and from San Luis Obispo, CA and Santa Ana, CA

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