4.9
4.6Live departures
Santa Ana, CA to San Luis Obispo, CA bus times
The table below shows live departures for Santa Ana, CA to San Luis Obispo, CA buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 9:20 PM Santa Ana, CA | 16h05 | 1:25 PM San Luis Obispo, CA | 1 transfer | |
This is the last bus of the day. | |||||
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Compare prices and tickets Santa Ana, CA to San Luis Obispo, CA by train
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Journey information
Overview: Bus from Santa Ana, CA to San Luis Obispo, CA
USAUSA
Take a bus from Santa Ana, CA to San Luis Obispo, CA and enjoy the approximately 191 miles (308 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 03:45, the last at 23:45.
Distance 191 miles (308 km) |
Buses per day 5 |
First bus 03:45 |
Last bus 23:45 |
Cheapest month Oct |
Cheapest day Fri |
High season Oct - Dec |
Low season Jan - Mar |
Busiest day Wed |
Least busy day Wed |
Best day to book ahead 21 days |
FAQs: Bus from Santa Ana, CA to San Luis Obispo, CA
Find answers to the most common questions about traveling from Santa Ana, CA to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.
- Bubblegum Alley, a narrow alleyway famous for its walls covered in layers of chewed gum left by visitors
- Mission San Luis Obispo de Tolosa, a historic Spanish mission founded in 1772 with a museum and beautiful gardens
- Bishop Peak, a popular hiking destination offering panoramic views of the city and surrounding landscapes
- San Luis Obispo Museum of Art, a contemporary art museum showcasing works by regional and national artists
- Avila Beach, a nearby coastal spot known for its sandy shores and scenic pier.
- Stroll through Downtown SLO, a vibrant area with shops, restaurants, and the famous Thursday Night Farmers' Market
- Attend a performance at the Fremont Theater, a historic venue known for its art deco architecture and live events
- Visit the San Luis Obispo Children's Museum, offering interactive exhibits and activities for kids
- Explore the local wineries and vineyards, enjoying tastings and tours in the Edna Valley wine region
- Discover the natural beauty of Montana de Oro State Park, with its rugged cliffs, secluded beaches, and scenic hiking trails.
popular bus stations
Popular bus stations from Santa Ana, CA to San Luis Obispo, CA
Most popular bus connections from Santa Ana, CA
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