- Must visit
San Francisco Museum of Modern Art
Major modern and contemporary art museum with an internationally important collection and frequent blockbuster exhibitions.
Cheapest price
$445
Average price
$445
Fastest journey
2 d 13 h 15 m
Average duration
2 d 13 h 15 m
Buses per day
1
Distance
3637 km
The best way to find a cheap bus ticket from Pittsburgh, PA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to San Francisco, CA will cost around $445 if you buy it on the day, but the cheapest tickets can be found for only $445.
Of the 1 buses that leave Pittsburgh, PA for San Francisco, CA on Sat, Jul 11, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jul 11 the direct buses cover the 3637 km distance in an average of 2 d 13 h 15 m but if you time it right, some buses will get you there in just 2 d 13 h 15 m .
On Sat, Jul 11 the slowest buses will take 2 d 13 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Pittsburgh, PA to San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from $198. For those with little time consider booking a flight which can get you there in 6h 20m. The ticket price range depends on the travel mode: a flight costs an average of $198, and a train costs an average of $441.
Distance: 2259 miles (3637 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$390 Average price | $1265 Average price | $320 Average price Cheapest | $518 Average price (fuel + tolls) |
66h 15m Average total duration 65h 45m Onboard + 30m Additional time* | 63h 13m Average total duration 62h 43m Onboard + 30m Additional time* | 9h 20m Average total duration Fastest 6h 20m Onboard + 3h 0m Additional time* | 37h 40m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pittsburgh, PA to San Francisco, CA:
A flight is $70 (€58) less than a bus for this route with tickets for a bus from Pittsburgh, PA to San Francisco, CA costing on average $390 (€320).
A flight is $945 (€777) less than a train for this route with tickets for a train from Pittsburgh, PA to San Francisco, CA costing on average $1265 (€1040).
Other travel options to San Francisco, CA take longer:
Train takes on average 62h 43m.
Bus takes on average 65h 45m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 02:15PM | Duration 61h15 | Departure days Sat | Cheapest price $445 |
Operator Greyhound USA | Departure Time 01:35AM | Arrival Time 12:25PM | Duration 58h50 | Departure days Wed, Thu, Sat | Cheapest price $666 |
Operator Greyhound | Departure Time 06:35AM | Arrival Time 02:05AM | Duration 67h30 | Departure days Sun | Cheapest price $456 |
Operator Greyhound USA | Departure Time 08:00PM | Arrival Time 07:15AM | Duration 59h15 | Departure days Tue, Wed | Cheapest price $783 |
Operator Greyhound | Departure Time 08:15PM | Arrival Time 05:50PM | Duration 72h35 | Departure days Thu | Cheapest price $720 |
The table below shows live departures for Pittsburgh, PA to San Francisco, CA buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 1:35 AM Pittsburgh, Greyhound Bus Station, PA | 62h00 | 12:35 PM San Francisco, Transit Center Bay 29 | 3 transfers | |
· · · | 8:15 PM Pittsburgh, Greyhound Bus Station, PA | 61h55 | 7:10 AM San Francisco, Transit Center Bay 29 | 3 transfers | |
· · · | 8:15 PM Pittsburgh, Greyhound Bus Station, PA | 72h35 | 5:50 PM San Francisco, Townsend Street / 5th Street, CA | 4 transfers | |
| Friday, July 10 | |||||
![]() | 1:00 AM Pittsburgh, PA | 61h15 | 2:15 PM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pittsburgh, PA to San Francisco, CA run on average 6 times per day, taking around 65h 45m. Cheap bus tickets for this journey start at $173 (€142) if you book in advance.
The earliest bus runs at 01:35, the last at 23:25. The fastest bus covers the 2259 miles (3637 km) distance in 61h 15m.
Distance 2259 miles (3637 km) |
Average bus duration 65h 45m |
Cheapest ticket price $173 (€142) |
Buses per day 6 |
Fastest bus 61h 15m |
First bus 1:35 AM |
Last bus 11:25 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Major modern and contemporary art museum with an internationally important collection and frequent blockbuster exhibitions.
Hands-on science and art museum on the Embarcadero, especially popular for interactive exhibits and bay views.
Leading fine arts museum in Golden Gate Park, known for American art, textiles, and its observation tower.
Busy waterfront district known for classic San Francisco atmosphere, bay views, piers, and easy access to major sights.
Famous crooked block with steep curves, manicured gardens, and one of the city's most photographed street scenes.
Huge urban park with gardens, lakes, museums, and broad walking and cycling routes across the western city.
A tomato-based seafood stew created by Italian American fishermen in San Francisco, typically filled with crab, clams, mussels, shrimp, and fish.
San Francisco’s famous tangy sourdough loaf, shaped by the city’s historic wild yeast culture and long baking tradition.
A large foil-wrapped burrito associated with the Mission District, usually packed with rice, beans, meat, salsa, and extras.
Classic San Francisco institution serving carved prime rib with old-fashioned hospitality and a lively, upscale supper-club feel.
Iconic Mission District taqueria celebrated for Mission-style burritos and tacos with a simple, always-busy casual atmosphere.
Historic seafood counter famous for ultra-fresh oysters, crab, and cioppino ingredients in a classic old-school San Francisco setting.
Prices are high for hotels, dining, parking, and taxes. Budget options exist, but overall costs rank among the highest in the US.
Tip 18-20% in restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15% or round up. Hotels: USD 2-5 for porters, USD 3-5 daily for housekeeping.
Find answers to the most common questions about traveling from Pittsburgh, PA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Pittsburgh, PA to San Francisco, CA buses use the Pittsburgh, Greyhound Bus Station to San Francisco, Townsend Street / 5th Street station pair, with some services arriving at San Francisco, Transit Center Bay 29. Use this guide to compare Pittsburgh, PA and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need