The cheapest and fastest buses from Pittsburgh, PA to Chicago, IL
Cheapest price
$65
Average price
$84
Fastest journey
10 h 20 m
Average duration
12 h 14 m
Buses per day
8
Distance
660 km
The best way to find a cheap bus ticket from Pittsburgh, PA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Chicago, IL will cost around $84 if you buy it on the day, but the cheapest tickets can be found for only $65.
Of the 8 buses that leave Pittsburgh, PA for Chicago, IL on Fri, Nov 07, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 660 km distance in an average of 12 h 14 m but if you time it right, some buses will get you there in just 10 h 20 m .
On Fri, Nov 07 the slowest buses will take 13 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


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Compare train, bus, and flight for Pittsburgh, PA to Chicago, IL
Omio recommends booking the train as it is the most popular option from Pittsburgh, PA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €94. For those with little time consider booking a train which can get you there in 9h 47m. The ticket price range depends on the travel mode: a bus costs an average of €94, and a train costs an average of €138.
Distance: 410 miles (660 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€94 Average price Cheapest | €138 Average price |
12h 10m Average total duration 11h 40m Onboard + 30m Additional time* | 10h 17m Average total duration Fastest 9h 47m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Pittsburgh, PA to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:40AM | Arrival Time 10:00AM | Duration 10h20 | Departure days Wed, Fri | Cheapest price $62 |
Operator Greyhound | Departure Time 01:35AM | Arrival Time 02:35PM | Duration 14h00 | Departure days Wed, Fri | Cheapest price $72 |
Operator Greyhound | Departure Time 07:40AM | Arrival Time 08:05PM | Duration 13h25 | Departure days Wed, Fri | Cheapest price $62 |
Operator Greyhound | Departure Time 08:40AM | Arrival Time 08:05PM | Duration 12h25 | Departure days Wed, Fri | Cheapest price $72 |
Operator Greyhound | Departure Time 10:50AM | Arrival Time 11:35PM | Duration 13h45 | Departure days Wed, Fri | Cheapest price $72 |
Operator Greyhound | Departure Time 06:30PM | Arrival Time 07:50AM | Duration 14h20 | Departure days Wed, Fri | Cheapest price $72 |
Operator FlixBus | Departure Time 07:45PM | Arrival Time 06:10AM | Duration 11h25 | Departure days Wed, Fri | Cheapest price $65 |
Live departures
Pittsburgh, PA to Chicago, IL bus times
The table below shows live departures for Pittsburgh, PA to Chicago, IL buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:45 PM Pittsburgh, PA | 9h55 | 11:40 PM Chicago, IL | 0 transfersDirect | |
| Friday, November 7 | |||||
![]() | 1:35 AM Pittsburgh, PA | 12h15 | 1:50 PM Chicago, IL | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pittsburgh, PA to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
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Nov 13
Journey information
Overview: Bus from Pittsburgh, PA to Chicago, IL
Buses from Pittsburgh, PA to Chicago, IL run on average 8 times per day, taking around 11h 40m. Cheap bus tickets for this journey start at $115 (€94) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:40, the last at 23:15. The fastest bus covers the 410 miles (660 km) distance in 11h 25m.
Distance 410 miles (660 km) |
Average bus duration 11h 40m |
Cheapest ticket price $115 (€94) |
Buses per day 8 |
Direct buses 2 |
Fastest bus 11h 25m |
First bus 00:40 |
Last bus 23:15 |
Bus providers: Greyhound, FlixBus from Pittsburgh, PA to Chicago, ILYou can travel by bus between Pittsburgh, PA to Chicago, IL with Greyhound, FlixBus for as low as $115 (€94). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Pittsburgh, PA to Chicago, IL
Find answers to the most common questions about traveling from Pittsburgh, PA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Pittsburgh, PA to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Pittsburgh, PA to Chicago, IL
Most popular bus connections from Pittsburgh, PA
More options for your journey from Pittsburgh, PA to Chicago, IL
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