- Must visit
Art Institute Of Chicago
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
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The cheapest and fastest buses from Pittsburgh, PA to Chicago, IL
Showing times and prices for Jun 21
Cheapest price
$134
Average price
$150
Fastest journey
10 h 5 m
Average duration
11 h 50 m
Buses per day
9
Distance
660 km
Cheap tickets
The best way to find a cheap bus ticket from Pittsburgh, PA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Chicago, IL will cost around $150 if you buy it on the day, but the cheapest tickets can be found for only $134.
Fast buses
Of the 9 buses that leave Pittsburgh, PA for Chicago, IL on Sun, Jun 21, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 660 km distance in an average of 11 h 50 m but if you time it right, some buses will get you there in just 10 h 5 m .
On Sun, Jun 21 the slowest buses will take 12 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus7:45 PM11h25Pittsburgh, Greyhound Bus Station, PA6:10 AMChicago, Greyhound Bus Station$1341One-way0 transfers
· 1:25 AM13h20Pittsburgh, Greyhound Bus Station, PA1:45 PMChicago, Union Station (Amtrak), IL$1381One-way1 transfer- · 8:50 AM12h15Pittsburgh, Greyhound Bus Station, PA8:05 PMChicago, Greyhound Bus Station$1381One-way1 transfer
- 8:35 AM12h30Pittsburgh, Greyhound Bus Station, PA8:05 PMChicago, Greyhound Bus Station$1421One-way0 transfers
- 12:55 AM10h05Pittsburgh, Greyhound Bus Station, PA10:00 AMChicago, Greyhound Bus Station$1511One-way0 transfers
- 12:55 AM10h05Pittsburgh, Greyhound Bus Station, PA10:00 AMChicago, Greyhound Bus Station$1511One-way0 transfers
- FlixBus7:45 PM11h25Pittsburgh, Greyhound Bus Station, PA6:10 AMChicago, Greyhound Bus Station$1341One-way0 transfers
- · 8:50 AM12h15Pittsburgh, Greyhound Bus Station, PA8:05 PMChicago, Greyhound Bus Station$1381One-way1 transfer
- 8:35 AM12h30Pittsburgh, Greyhound Bus Station, PA8:05 PMChicago, Greyhound Bus Station$1421One-way0 transfers
- FlixBus7:00 AM12h55Pittsburgh, Greyhound Bus Station, PA6:55 PMChicago, Greyhound Bus Station$1801One-way0 transfers
Travel Information
Compare train, bus, and flight for Pittsburgh, PA to Chicago, IL
Omio recommends booking the train as it is the most popular option from Pittsburgh, PA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $44. For those with little time consider booking a flight which can get you there in 2h 22m. The ticket price range depends on the travel mode: a bus costs an average of $44, and a flight costs an average of $74.
Distance: 410 miles (660 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$91 Average price Cheapest | $171 Average price | $304 Average price | $135 Average price (fuel + tolls) |
12h 11m Average total duration 11h 41m Onboard + 30m Additional time* | 10h 16m Average total duration 9h 46m Onboard + 30m Additional time* | 5h 22m Average total duration Fastest 2h 22m Onboard + 3h 0m Additional time* | 6h 37m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Pittsburgh, PA to Chicago, IL is a bus with an average price of $91 (€75).
This is compared to other travel options from Pittsburgh, PA to Chicago, IL:
A bus is $80 (€66) less than a train for this route with tickets for a train from Pittsburgh, PA to Chicago, IL costing on average $171 (€140).
A bus is $213 (€174) less than a flight for this route with tickets for a flight from Pittsburgh, PA to Chicago, IL costing on average $304 (€249).
The fastest way to travel from Pittsburgh, PA to Chicago, IL is by flight with an average journey time of 2h 22m.
Other travel options to Chicago, IL take longer:
Train takes on average 9h 46m.
Bus takes on average 11h 41m.
It's helpful to compare your options as there are 3 ways to travel between Pittsburgh, PA and Chicago, IL including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Pittsburgh, PA to Chicago, IL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $91 (€75) compared to roughly $135 (€111) in fuel and tolls — a saving of about $44 (€36). The journey takes 11h 41m versus 6h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound, FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Pittsburgh, PA to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 10:00AM | Duration 10h05 | Departure days Everyday | Cheapest price $73 |
Operator Greyhound | Departure Time 01:25AM | Arrival Time 01:25PM | Duration 13h00 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 07:00AM | Arrival Time 06:55PM | Duration 12h55 | Departure days Mon, Sat, Sun | Cheapest price $116 |
Operator Greyhound | Departure Time 08:35AM | Arrival Time 08:05PM | Duration 12h30 | Departure days Everyday | Cheapest price $69 |
Operator Greyhound | Departure Time 08:50AM | Arrival Time 08:05PM | Duration 12h15 | Departure days Everyday | Cheapest price $90 |
Operator FlixBus | Departure Time 07:45PM | Arrival Time 06:10AM | Duration 11h25 | Departure days Everyday | Cheapest price $75 |
Operator Greyhound | Departure Time 08:00PM | Arrival Time 08:25AM | Duration 13h25 | Departure days Everyday | Cheapest price $84 |
Live departures
Pittsburgh, PA to Chicago, IL bus times
The table below shows live departures for Pittsburgh, PA to Chicago, IL buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus | 7:45 PM Pittsburgh, Greyhound Bus Station, PA | 11h25 | 6:10 AM Chicago, Greyhound Bus Station | 0 transfersDirect | |
| · | 8:00 PM Pittsburgh, Greyhound Bus Station, PA | 13h00 | 8:00 AM Chicago, Union Station (Amtrak), IL | 1 transfer | |
| · | 8:00 PM Pittsburgh, Greyhound Bus Station, PA | 13h25 | 8:25 AM Chicago, Greyhound Bus Station | 1 transfer | |
| Sunday, June 21 | |||||
| 12:55 AM Pittsburgh, Greyhound Bus Station, PA | 10h05 | 10:00 AM Chicago, Greyhound Bus Station | 0 transfersDirect | |
| · | 1:25 AM Pittsburgh, Greyhound Bus Station, PA | 13h20 | 1:45 PM Chicago, Union Station (Amtrak), IL | 1 transfer | |
| +FlixBus | 1:25 AM Pittsburgh, Greyhound Bus Station, PA | 13h00 | 1:25 PM Chicago, Greyhound Bus Station | 1 transfer | |
| FlixBus | 7:00 AM Pittsburgh, Greyhound Bus Station, PA | 12h55 | 6:55 PM Chicago, Greyhound Bus Station | 0 transfersDirect | |
| 8:35 AM Pittsburgh, Greyhound Bus Station, PA | 12h30 | 8:05 PM Chicago, Greyhound Bus Station | 0 transfersDirect | |
| · | 8:50 AM Pittsburgh, Greyhound Bus Station, PA | 12h15 | 8:05 PM Chicago, Greyhound Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pittsburgh, PA to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pittsburgh, PA to Chicago, IL buses with Omio?
Greyhound as well as FlixBus offer buses services from Pittsburgh, PA to Chicago, IL.
Omio is an official ticket reseller for all your travel options from Pittsburgh, PA to Chicago, IL.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pittsburgh, PA to Chicago, IL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Chicago, IL.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pittsburgh, PA to Chicago, IL.
Journey information
Overview: Bus from Pittsburgh, PA to Chicago, IL
USAUSA
Buses from Pittsburgh, PA to Chicago, IL run on average 8 times per day, taking around 11h 41m. Cheap bus tickets for this journey start at $44 (€36) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:40, the last at 23:50. The fastest bus covers the 410 miles (660 km) distance in 10h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 410 miles (660 km) |
Average bus duration 11h 41m |
Cheapest ticket price $44 (€36) |
Buses per day 8 |
Direct buses 3 |
Fastest bus 10h 5m |
First bus 12:40 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from Pittsburgh, PA to Chicago, ILYou can travel by bus between Pittsburgh, PA to Chicago, IL with Greyhound, FlixBus for as low as $44 (€36). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
11h 25m
Cheapest Price
$72 (€59)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
10h 5m
Cheapest Price
$44 (€36)
Greyhound frequency
7 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Chicago
Things to do in Chicago
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
- Must visit
Field Museum
Major natural history museum famous for Sue the T. rex, ancient cultures, and extensive science collections that appeal to both adults and children.
- Must visit
Museum Of Science And Industry
Large hands-on science museum in Hyde Park featuring a submarine, space exhibits, engineering displays, and immersive family-friendly experiences.
- Must visit
Millennium Park
The city’s signature public space, home to Cloud Gate, gardens, events, and major skyline views that define modern Chicago.
- Must visit
The Magnificent Mile
Famous stretch of Michigan Avenue lined with historic buildings, shops, hotels, and frequent first-time visitor photo stops.
- Must visit
Chicago Riverwalk
Highly popular waterfront promenade with architecture views, bridges, and one of the best urban walks in the city.
Deep-Dish Pizza
Chicago’s iconic thick-crust pizza baked in a deep pan, layered with cheese, toppings, and chunky tomato sauce. It is one of the city’s most famous comfort foods.
Chicago-Style Hot Dog
An all-beef hot dog on a poppy seed bun topped with mustard, onions, neon relish, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food.
Italian Beef Sandwich
Thinly sliced roast beef piled onto an Italian roll, often dipped in seasoned jus and topped with sweet peppers or giardiniera. It is a defining Chicago sandwich.
Gene & Georgetti
A historic old-school steakhouse serving steaks, chops, and classic Italian-American dishes in a traditional setting.
Alinea
Chicago’s internationally acclaimed fine-dining restaurant known for highly inventive tasting menus and exceptional service.
Lou Malnati's Pizzeria
A long-established Chicago favorite known for buttery deep-dish pizza and a casual, family-friendly atmosphere.
United States Dollar
Moderate for a major U.S. city: casual food is manageable, but hotels, attractions, and downtown dining can be pricey.
Average meal costs
- Budget
- USD 10-18 for fast food or casual takeout.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 75+ per person before drinks and tax.
- Coffee
- USD 4-7 for a regular café coffee.
Tipping culture
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and hotel staff a few dollars.
FAQs: Bus from Pittsburgh, PA to Chicago, IL
Find answers to the most common questions about traveling from Pittsburgh, PA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pittsburgh, PA to Chicago, IL can start from as little as $44 (€36) when you book in advance. The average bus ticket price for Pittsburgh, PA to Chicago, IL is $91 (€75) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pittsburgh, PA to Chicago, IL is 10h 5m to travel the 410 miles (660 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pittsburgh, PA to Chicago, IL leaves at 12:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pittsburgh, PA to Chicago, IL leaves at 11:50 PM.
Yes, there are 3 direct buses a day from Pittsburgh, PA to Chicago, IL with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Pittsburgh, PA to Chicago, IL, you can count on Greyhound, FlixBus for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between Pittsburgh, PA and Chicago, IL and compare the amenities they offer before buying a bus ticket.
A trip to Chicago, IL from Pittsburgh, PA is worth doing but not as a day trip with a journey time of 10h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pittsburgh, PA to Chicago, IL is September.
It's helpful to compare your options as there are 3 ways to travel between Pittsburgh, PA and Chicago, IL including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pittsburgh, PA to Chicago, IL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pittsburgh, PA to Chicago, IL for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
Whether you can cancel your bus ticket from Pittsburgh, PA to Chicago, IL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pittsburgh, PA to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from Pittsburgh, PA to Chicago, IL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pittsburgh, PA to Chicago, IL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pittsburgh, PA to Chicago, IL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pittsburgh, PA to Chicago, IL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Pittsburgh, PA to Chicago, IL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Pittsburgh, PA to Chicago, IL with the following bus company: Greyhound, FlixBus.
Since neither Pittsburgh, PA nor Chicago, IL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Pittsburgh, PA to Chicago, IL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pittsburgh, PA to Chicago, IL
Most Pittsburgh, PA to Chicago, IL buses use the Pittsburgh, Greyhound Bus Station to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Pittsburgh, PA and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Pittsburgh
Arrival bus stations in Chicago
Pittsburgh, Greyhound Bus Station
City-centre transport
Getting to Pittsburgh, Greyhound Bus Station from Pittsburgh city centre
Bus29, 31, 39, 40, 41, 44, G3, G31, P1 · 3m · every ~27 min
M · 7m
1F, 2F, 3F, 14F · 12m · $1
Chicago, Greyhound Bus Station
City-centre transport
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Bus7 · 8m · $4 · every ~6 min
Chicago, Union Station (Amtrak)
City-centre transport
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Bus28, 151 · 7m · $4 · every ~13 min
Most popular bus connections from Pittsburgh, PA
More options for your journey from Pittsburgh, PA to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Pittsburgh, PA
Most popular bus connections to Chicago, IL
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