2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Pittsburgh, PA to Chicago, IL
Showing times and prices for Mar 24
Cheapest price
$71
Average price
$100
Fastest journey
10 h 20 m
Average duration
12 h 23 m
Buses per day
3
Distance
660 km
Cheap tickets
The best way to find a cheap bus ticket from Pittsburgh, PA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Chicago, IL will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $71.
Fast buses
Of the 3 buses that leave Pittsburgh, PA for Chicago, IL on Tue, Mar 24, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct buses cover the 660 km distance in an average of 12 h 23 m but if you time it right, some buses will get you there in just 10 h 20 m .
On Tue, Mar 24 the slowest buses will take 13 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
01:00AM13h25
Pittsburgh, PA02:25PMChicago, IL
$711One-way
0 transfers
12:40PM13h25
Pittsburgh, PA02:05AMChicago, IL
$1091One-way
0 transfers
05:40AM10h20
Pittsburgh, PA04:00PMChicago, IL
$1201One-way
0 transfers
05:40AM10h20
Pittsburgh, PA04:00PMChicago, IL
$1201One-way
0 transfers
12:40PM13h25
Pittsburgh, PA02:05AMChicago, IL
$1091One-way
0 transfers
01:00AM13h25
Pittsburgh, PA02:25PMChicago, IL
$711One-way
0 transfers
Travel Information
Compare train, bus, and flight for Pittsburgh, PA to Chicago, IL
Omio recommends booking the train as it is the most popular option from Pittsburgh, PA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a flight which can get you there in 2h 21m. The ticket price range depends on the travel mode: a bus costs an average of $58, and a flight costs an average of $52.
Distance: 410 miles (660 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$98 Average price Cheapest | $135 Average price | $300 Average price |
12h 2m Average total duration 11h 32m Onboard + 30m Additional time* | 10h 16m Average total duration 9h 46m Onboard + 30m Additional time* | 5h 21m Average total duration Fastest 2h 21m Onboard + 3h 0m Additional time* |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Pittsburgh, PA to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 10:00AM | Duration 10h05 | Departure days Tue, Wed, Thu, Sun | Cheapest price $72 |
Operator Greyhound | Departure Time 01:20AM | Arrival Time 02:35PM | Duration 14h15 | Departure days Tue, Wed, Thu, Sun | Cheapest price $94 |
Operator FlixBus | Departure Time 01:25AM | Arrival Time 05:35PM | Duration 17h10 | Departure days Tue, Wed, Thu, Sun | Cheapest price $95 |
Operator Greyhound | Departure Time 08:35AM | Arrival Time 08:05PM | Duration 12h30 | Departure days Tue, Wed, Thu, Sun | Cheapest price $68 |
Operator Greyhound | Departure Time 08:50AM | Arrival Time 08:05PM | Duration 12h15 | Departure days Tue, Wed, Thu, Sun | Cheapest price $91 |
Operator FlixBus | Departure Time 07:45PM | Arrival Time 06:10AM | Duration 11h25 | Departure days Tue, Wed, Thu, Sun | Cheapest price $76 |
Operator Greyhound | Departure Time 08:00PM | Arrival Time 08:25AM | Duration 13h25 | Departure days Tue, Wed, Thu, Sun | Cheapest price $96 |
Live departures
Pittsburgh, PA to Chicago, IL bus times
The table below shows live departures for Pittsburgh, PA to Chicago, IL buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
Last updated at 1:38 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 FlixBus | 11:45 PM Pittsburgh, Greyhound Bus Station, PA | 11h25 | 11:10 AM Chicago, Greyhound Bus Station | 0 transfersDirect | |
| Monday, March 23 | |||||
| undefined · undefined | 12:00 AM Pittsburgh, Greyhound Bus Station, PA | 13h25 | 1:25 PM Chicago, Greyhound Bus Station | 1 transfer | |
| undefined · undefined | 12:00 AM Pittsburgh, Greyhound Bus Station, PA | 13h00 | 1:00 PM Chicago, Union Station (Amtrak), IL | 1 transfer | |
| 1:00 AM Pittsburgh, PA | 13h25 | 2:25 PM Chicago, IL | 0 transfersDirect | |
| 5:40 AM Pittsburgh, PA | 10h20 | 4:00 PM Chicago, IL | 0 transfersDirect | |
| 12:40 PM Pittsburgh, PA | 13h25 | 2:05 AM Chicago, IL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pittsburgh, PA to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Mar 22
Mar 22
Mon
Mar 23
Mar 23
Tue
Mar 24
Mar 24
Wed
Mar 25
Mar 25
Thu
Mar 26
Mar 26
Fri
Mar 27
Mar 27
Sat
Mar 28
Mar 28
Sun
Mar 29
Mar 29
Mon
Mar 30
Mar 30
Tue
Mar 31
Mar 31
Wed
Apr 01
Apr 01
Thu
Apr 02
Apr 02
Fri
Apr 03
Apr 03
Sat
Apr 04
Apr 04
Sun
Apr 05
Apr 05
Mon
Apr 06
Apr 06
Tue
Apr 07
Apr 07
Wed
Apr 08
Apr 08
Thu
Apr 09
Apr 09
Fri
Apr 10
Apr 10
Sat
Apr 11
Apr 11
Why should you book Pittsburgh, PA to Chicago, IL buses with Omio?
Greyhound as well as FlixBus offer buses services from Pittsburgh, PA to Chicago, IL.
Omio is an official ticket reseller for all your travel options from Pittsburgh, PA to Chicago, IL.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Chicago, IL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pittsburgh, PA to Chicago, IL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Pittsburgh, PA to Chicago, IL.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pittsburgh, PA to Chicago, IL.
Journey information
Overview: Bus from Pittsburgh, PA to Chicago, IL
USAUSA
Buses from Pittsburgh, PA to Chicago, IL run on average 8 times per day, taking around 11h 32m. Cheap bus tickets for this journey start at $58 (€47) but you can travel from only $52 (€42) by flight.
There are 3 buses per day. The earliest bus runs at 00:40, the last at 23:50. The fastest bus covers the 410 miles (660 km) distance in 10h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $52 (€42)
Distance 410 miles (660 km) |
Average bus duration 11h 32m |
Cheapest ticket price $58 (€47) |
Buses per day 8 |
Direct buses 3 |
Fastest bus 10h 5m |
First bus 00:40 |
Last bus 23:50 |
Cheapest month Sep |
Cheapest day Mon |
High season Oct - Dec |
Low season Apr - Jun |
Busiest day Mon |
Least busy day Wed |
Best day to book ahead 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $52 (€42)
Bus providers: Greyhound, FlixBus from Pittsburgh, PA to Chicago, ILYou can travel by bus between Pittsburgh, PA to Chicago, IL with Greyhound, FlixBus for as low as $52 (€42). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
11h 25m
Cheapest Price
$64 (€52)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
10h 5m
Cheapest Price
$58 (€47)
Greyhound frequency
7 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from Pittsburgh, PA to Chicago, IL
Find answers to the most common questions about traveling from Pittsburgh, PA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pittsburgh, PA to Chicago, IL can start from as little as $58 (€47) when you book in advance. The average bus ticket price for Pittsburgh, PA to Chicago, IL is $98 (€80) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pittsburgh, PA to Chicago, IL is 10h 5m to travel the 410 miles (660 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pittsburgh, PA to Chicago, IL leaves at 12:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pittsburgh, PA to Chicago, IL leaves at 11:50 PM.
Yes, there are 3 direct buses a day from Pittsburgh, PA to Chicago, IL with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Pittsburgh, PA to Chicago, IL, you can count on Greyhound, FlixBus for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between Pittsburgh, PA and Chicago, IL and compare the amenities they offer before buying a bus ticket.
A trip to Chicago, IL from Pittsburgh, PA is worth doing but not as a day trip with a journey time of 10h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pittsburgh, PA to Chicago, IL is September.
It's helpful to compare your options as there are 3 ways to travel between Pittsburgh, PA and Chicago, IL including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Pittsburgh, PA to Chicago, IL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Pittsburgh, PA to Chicago, IL for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
Whether you can cancel your bus ticket from Pittsburgh, PA to Chicago, IL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pittsburgh, PA to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from Pittsburgh, PA to Chicago, IL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pittsburgh, PA to Chicago, IL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pittsburgh, PA to Chicago, IL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pittsburgh, PA to Chicago, IL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Pittsburgh, PA to Chicago, IL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Pittsburgh, PA to Chicago, IL with the following bus company: Greyhound, FlixBus.
popular bus stations
Popular bus stations from Pittsburgh, PA to Chicago, IL
Pittsburgh
Chicago
The major bus station for departures in Pittsburgh is Pittsburgh, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Pittsburgh, Greyhound Bus Station for your trip from Pittsburgh to Chicago.
Pittsburgh, Greyhound Bus Station
information
The major bus station for arrivals in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip to Chicago from Pittsburgh.
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
Most popular bus connections from Pittsburgh, PA
More options for your journey from Pittsburgh, PA to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Pittsburgh, PA
Most popular bus connections to Chicago, IL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
