The cheapest and fastest trains from Florence, SC to Wilmington, DE
Cheapest price
$259
Average price
$259
Fastest journey
9 h 51 m
Average duration
10 h 12 m
Trains per day
2
Distance
722 km
The best way to find a cheap train ticket from Florence, SC to Wilmington, DE is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence, SC to Wilmington, DE will cost around $259 if you buy it on the day, but the cheapest tickets can be found for only $259.
Of the 2 trains that leave Florence, SC for Wilmington, DE on Sun, Mar 22, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct trains cover the 722 km distance in an average of 10 h 12 m but if you time it right, some trains will get you there in just 9 h 51 m .
On Sun, Mar 22 the slowest trains will take 10 h 32 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train and bus for Florence, SC to Wilmington, DE
Omio recommends booking the train as it is the most popular option from Florence, SC to Wilmington, DE among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a train which can get you there in 10h 15m. The ticket price range depends on the travel mode: a bus costs an average of $72, and a train costs an average of $121.
Distance: 448 miles (722 km)
Compare train with
Most popular Train | Bus |
|---|---|
$145 Average price | $129 Average price Cheapest |
10h 45m Average total duration Fastest 10h 15m Onboard + 30m Additional time* | 13h 55m Average total duration 13h 25m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Florence, SC to Wilmington, DE train times
The table below shows live departures for Florence, SC to Wilmington, DE trains for today, Saturday, March 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:54 PM Florence, SC | 10h32 | 2:26 AM Wilmington, DE | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence, SC to Wilmington, DE by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Journey information
Overview: Train from Florence, SC to Wilmington, DE
Trains from Florence, SC to Wilmington, DE run on average 2 times per day, taking around 10h 15m. Cheap train tickets for this journey start at $121 (€98) but you can travel from only $72 (€58) by bus.
There are 2 trains per day. The earliest train runs at 07:51, the last at 23:32. The fastest train covers the 448 miles (722 km) distance in 10h 32m.
Distance 448 miles (722 km) |
Average train duration 10h 15m |
Cheapest ticket price $121 (€98) |
Trains per day 2 |
Direct trains 2 |
Fastest train 10h 32m |
First train 07:51 |
Last train 23:32 |
Cheapest month Nov |
Cheapest day Mon |
High season Oct - Dec |
Low season Jul - Sep |
Busiest day Fri |
Least busy day Fri |
Best day to book ahead 1 day |
Train companies: Amtrak from Florence, SC to Wilmington, DE trainsAmtrak trains will get you between Florence, SC and Wilmington, DE from $72 (€58). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Florence, SC to Wilmington, DE
Find answers to the most common questions about traveling from Florence, SC to Wilmington, DE by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Wilmington, DE, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence, SC to Wilmington, DE
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Greyhound services available nearby
- 5:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 24/7. Access via Martin Luther King Jr. Blvd.
- Mikimotos Asian Grill & Sushi Bar
- La Fia Bistro
- Outside the main entrance.
- Ramps, restrooms.
- $0.50
- Hotel du Pont
- Sheraton Suites Wilmington Downtown
- Courtyard by Marriott Wilmington Downtown
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-6 for Amtrak and SEPTA services
- Bus: Several DART First State bus lines available
- Amtrak: Northeast Corridor services
- SEPTA: Wilmington/Newark Line
Most popular train connections from Florence, SC
More options for your journey from Florence, SC to Wilmington, DE
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