The cheapest and fastest buses from Durham, NC to Charleston, SC
Cheapest price
$0.00
Average price
$-0.01
Fastest journey
1 d 39 m
Average duration
1 d 39 m
Buses per day
1
Distance
370 km
The best way to find a cheap bus ticket from Durham, NC to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Durham, NC to Charleston, SC without transferring at least 3 times.


Travel Information
Compare bus, flight, and train for Durham, NC to Charleston, SC
Omio recommends booking the train as it is the most popular option from Durham, NC to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $81. For those with little time consider booking a flight which can get you there in 3h 20m. The ticket price range depends on the travel mode: a bus costs an average of $81, and a flight costs an average of $51.
Distance: 229 miles (370 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$81 Average price Cheapest | $97 Average price | $296 Average price |
17h 30m Average total duration 17h 0m Onboard + 30m Additional time* | 6h 51m Average total duration 6h 21m Onboard + 30m Additional time* | 6h 20m Average total duration Fastest 3h 20m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Durham, NC to Charleston, SC bus times
The table below shows live departures for Durham, NC to Charleston, SC buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:30 AM Durham, NC | 24h39 | 7:09 AM Charleston, SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Durham, NC to Charleston, SC by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
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Mar 24
Mar 25
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Mar 28
Why should you book Durham, NC to Charleston, SC buses with Omio?
Why book with Omio vs Go Triangle?
- Compare with other providers: On Omio, you can not only buy tickets for Go Triangle, but also compare tickets for the likes of Greyhound or FlixBus to find the best option for your trip from Durham, NC to Charleston, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Go Triangle with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Durham, NC to Charleston, SC.
Journey information
Overview: Bus from Durham, NC to Charleston, SC
Buses from Durham, NC to Charleston, SC run on average 2 times per day, taking around 17h 0m. Cheap bus tickets for this journey start at $81 (€65) but you can travel from only $51 (€41) by flight.
The earliest bus runs at 11:15, the last at 22:10. The fastest bus covers the 229 miles (370 km) distance in 17h 0m.
Distance 229 miles (370 km) |
Average bus duration 17h 0m |
Cheapest ticket price $81 (€65) |
Buses per day 2 |
Fastest bus 17h 0m |
First bus 11:15 |
Last bus 22:10 |
Cheapest month Jul |
Cheapest day Sun |
High season Apr - Jun |
Low season Jan - Mar |
Bus providers: Go Triangle, Greyhound, FlixBus from Durham, NC to Charleston, SCYou can travel by bus between Durham, NC to Charleston, SC with Go Triangle, Greyhound, FlixBus for as low as $51 (€41). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
Go Triangle
FAQs: Bus from Durham, NC to Charleston, SC
Find answers to the most common questions about traveling from Durham, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Durham, NC to Charleston, SC
Most popular bus connections from Durham, NC
More options for your journey from Durham, NC to Charleston, SC
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