The cheapest and fastest buses from Durham, NC to Charleston, SC
Cheapest price
$87
Average price
$114
Fastest journey
8 h 41 m
Average duration
19 h 34 m
Buses per day
2
Distance
370 km
The best way to find a cheap bus ticket from Durham, NC to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Charleston, SC will cost around $114 if you buy it on the day, but the cheapest tickets can be found for only $87.
It's difficult to get from Durham, NC to Charleston, SC without transferring at least 3 times.




Live departures
Durham, NC to Charleston, SC bus times
The table below shows live departures for Durham, NC to Charleston, SC buses for tomorrow, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:00 AM Durham, NC | 8h41 | 3:41 PM Charleston, SC | 4 transfers | |
![]() | 9:15 AM Durham, NC | 30h26 | 3:41 PM Charleston, SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Durham, NC to Charleston, SC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Nov 12
Journey information
Overview: Bus from Durham, NC to Charleston, SC
Buses from Durham, NC to Charleston, SC run on average 1 times per day, taking around 20h 31m. Cheap bus tickets for this journey start at $87 (€71) if you book in advance.
The earliest bus runs at 13:55, the last at 22:10. The fastest bus covers the 229 miles (370 km) distance in 8h 41m.
Distance 229 miles (370 km) |
Average bus duration 20h 31m |
Cheapest ticket price $87 (€71) |
Buses per day 1 |
Fastest bus 8h 41m |
First bus 13:55 |
Last bus 22:10 |
Bus providers: Go Triangle, Greyhound, FlixBus from Durham, NC to Charleston, SCYou can travel by bus between Durham, NC to Charleston, SC with Go Triangle, Greyhound, FlixBus for as low as $87 (€71). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
Go Triangle
FAQs: Bus from Durham, NC to Charleston, SC
Find answers to the most common questions about traveling from Durham, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Durham, NC to Charleston, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Durham, NC to Charleston, SC
Most popular bus connections from Durham, NC
More options for your journey from Durham, NC to Charleston, SC
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