- Must visit
Nasher Museum of Art
Major art museum at Duke with global collections, rotating exhibitions, and strong programs in modern and classical art.
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Travel Information
Compare bus, train, and flight for Charleston, SC to Durham, NC
Omio recommends booking the bus as it is the most popular option from Charleston, SC to Durham, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €76 For those with little time, consider booking a flight, which has an average total journey time of 4h 50m. Average ticket prices depend on the travel mode: a bus costs an average of €76, while a flight costs an average of €472.
Distance: 229 miles (370 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
€76 Average price Cheapest | €472 Average price | €92 Average price | €44 Average price (fuel + tolls) |
8h 49m Average total duration 8h 19m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 2h 50m Onboard + 2h 0m Additional time* | 6h 39m Average total duration 6h 9m Onboard + 30m Additional time* | 4h 31m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Charleston, SC to Durham, NC is a bus with an average price of €76.
This is compared to other travel options from Charleston, SC to Durham, NC:
A bus is €16 less than a train for this route with tickets for a train from Charleston, SC to Durham, NC costing on average €92.
A bus is €397 less than a flight for this route with tickets for a flight from Charleston, SC to Durham, NC costing on average €472.
The fastest way to travel from Charleston, SC to Durham, NC is by flight with an average journey time of 2h 50m.
Other travel options to Durham, NC take longer:
Train takes on average 6h 9m.
Bus takes on average 8h 19m.
It's helpful to compare your options as there are 3 ways to travel between Charleston, SC and Durham, NC including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Charleston, SC to Durham, NC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around €76 compared to roughly €44 in fuel and tolls — a saving of about €-31.71. The journey takes 8h 19m versus 4h 31m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Charleston, SC to Durham, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator CARTA | Departure Time 10:05AM | Arrival Time 10:00PM | Duration 11h55 | Departure days Thu, Fri | Cheapest price €0.00 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 02:00AM | Duration 10h45 | Departure days Tue, Wed, Sat | Cheapest price €53 |
Operator Greyhound | Departure Time 04:15PM | Arrival Time 03:00AM | Duration 10h45 | Departure days Mon | Cheapest price €71 |
Live departures
Charleston, SC to Durham, NC bus times
The table below shows live departures for Charleston, SC to Durham, NC buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 3:15 PM Charleston, SC | 10h45 | 2:00 AM Durham, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Charleston, SC to Durham, NC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Charleston, SC to Durham, NC buses with Omio?
Greyhound operates all buses services from Charleston, SC to Durham, NC.
Omio is an official ticket reseller for all your travel options from Charleston, SC to Durham, NC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Charleston, SC to Durham, NC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Charleston, SC to Durham, NC.
Journey information
Overview: Bus from Charleston, SC to Durham, NC
USAUSA
Buses from Charleston, SC to Durham, NC run on average 2 times per day, taking around 8h 19m. Cheap bus tickets for this journey start at €39 if you book in advance.
The earliest bus runs at 11:15, the last at 22:10. The fastest bus covers the 229 miles (370 km) distance in 7h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 229 miles (370 km) |
Average bus duration 8h 19m |
Cheapest ticket price €39 |
Buses per day 2 |
Fastest bus 7h 0m |
First bus 11:15 AM |
Last bus 10:10 PM |
Cheapest Month Nov |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Charleston, SC to Durham, NCYou can travel by bus between Charleston, SC to Durham, NC with Greyhound for as low as €39. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
7h 0m
Cheapest Greyhound Price
€39
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Durham, NC
Things to do in Durham, NC
Discover the best of Durham, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Durham, NC trip today.
- Must visit
Museum of Life and Science
Hands-on science museum with aerospace, physics, wildlife, and family exhibits in downtown Durham.
- Recommended
Duke Homestead State Historic Site
Historic site and museum exploring Washington Duke, tobacco farming, and Durham's industrial origins.
- Must visit
Sarah P. Duke Gardens
Beloved public garden with terraces, woodland paths, and seasonal blooms, ideal for a scenic walk near Duke.
- Must visit
Downtown Durham
Lively downtown district for walking among warehouses, public art, music venues, and restored tobacco-era spaces.
- Must visit
American Tobacco Trail
Scenic riverside greenway for walking and cycling, connecting downtown with quiet stretches of restored nature.
- Gluten-free
Eastern NC Pork Barbecue
Eastern North Carolina chopped pork barbecue with a tangy vinegar-pepper sauce. A defining regional staple widely loved across Durham and the Triangle.
Pulled Pork Plate
Slow-cooked pork shoulder or whole hog, often served on a plate with slaw and hush puppies. It reflects the area’s deep barbecue tradition.
- Vegetarian
Hush Puppies
Fried cornmeal batter balls served with barbecue or seafood. They are a classic Southern side found on many Durham menus.
M Pocha
Refined restaurant showcasing seasonal North Carolina ingredients with polished service. Known for elevated Southern cooking and a stylish setting.
Guglhupf Bakery & Cafe
Beloved local bakery and café serving excellent pastries, breads, and coffee. A dependable stop for breakfast, lunch, or a quick snack.
True Flavors Diner
Popular casual spot for inventive biscuit sandwiches, shrimp and grits, and Southern brunch favorites in a lively downtown atmosphere.
US Dollar ($)
Moderate for a US college city; hotels and dining are mid-priced, transit is limited, but many casual meals and coffee shops are affordable.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-40 per person for a mid-range meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.
FAQs: Bus from Charleston, SC to Durham, NC
Find answers to the most common questions about traveling from Charleston, SC to Durham, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Charleston, SC to Durham, NC can start from as little as €39 when you book in advance. The average bus ticket price for Charleston, SC to Durham, NC is €76 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Charleston, SC to Durham, NC is 7h 0m to travel the 229 miles (370 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Charleston, SC to Durham, NC leaves at 11:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Charleston, SC to Durham, NC leaves at 10:10 PM.
There are 2 buses a day from Charleston, SC to Durham, NC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Charleston, SC to Durham, NC, you can count on Greyhound for the best way to get you to Durham, NC. You can also check all possible bus companies who offer a service between Charleston, SC and Durham, NC and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Charleston, Gaynor Avenue (Greyhound Bus Station), SC, which is located around 7 miles (12 km) away from the city centre, and they get off the bus at Durham Station, located 0 away from the city centre.
A trip to Durham, NC from Charleston, SC is worth doing but not as a day trip with a journey time of 7h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Charleston, SC to Durham, NC is November.
It's helpful to compare your options as there are 3 ways to travel between Charleston, SC and Durham, NC including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Charleston, SC to Durham, NC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Charleston, SC to Durham, NC for bus company Greyhound.
Whether you can cancel your bus ticket from Charleston, SC to Durham, NC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Charleston, SC to Durham, NC.
Yes, the following luggage options are included when booking a bus ticket from Charleston, SC to Durham, NC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Charleston, SC to Durham, NC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Charleston, SC to Durham, NC.
You can reserve your seat on the bus from Charleston, SC to Durham, NC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Charleston, SC to Durham, NC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Charleston, SC to Durham, NC with the following bus company: Greyhound.
Since neither Charleston, SC nor Durham, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Charleston, SC to Durham, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Durham, NC, travelers should stay alert to common urban safety concerns such as petty theft, especially in crowded areas and public transit. Scams may include overcharging by unofficial taxi services or ride-share drivers, so using reputable transportation apps is advised. It's also important to avoid isolated areas after dark and keep personal belongings secure to reduce risk.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Charleston, SC to Durham, NC
Most Charleston, SC to Durham, NC buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Durham, W Pettigrew St (Greyhound Bus Station) station pair. Use this guide to compare Charleston, SC and Durham, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Charleston
Arrival bus stations in Durham
Which Charleston, SC station do buses to Durham, NC leave from?
Buses from Charleston, SC to Durham, NC leave from Charleston, Gaynor Avenue (Greyhound Bus Station). The station is 8 miles (13 km) from Charleston, SC city centre at 4565 Gaynor Ave, Charleston, SC 29405, USA.
Charleston, Gaynor Avenue (Greyhound Bus Station)4565 Gaynor Ave, Charleston, SC 29405, USA
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Durham, W Pettigrew St (Greyhound Bus Station)Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701
City-centre transport
Getting to Durham, W Pettigrew St (Greyhound Bus Station) from Durham city centre
Bus2, 9, 12, 12B · 5m · €1 · every ~12 min
Most popular bus connections from Charleston, SC
More options for your journey from Charleston, SC to Durham, NC
Here are some other resources that might have the information you need
Most popular buses to and from Durham, NC and Charleston, SC
Most popular bus connections to Durham, NC
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