The cheapest and fastest buses from Durham, NC to Harrisburg, PA
Cheapest price
$219
Average price
$219
Fastest journey
11 h 30 m
Average duration
11 h 30 m
Buses per day
1
Distance
507 km
The best way to find a cheap bus ticket from Durham, NC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Harrisburg, PA will cost around $219 if you buy it on the day, but the cheapest tickets can be found for only $219.
It's difficult to get from Durham, NC to Harrisburg, PA without transferring at least once.


Live departures
Durham, NC to Harrisburg, PA bus times
The table below shows live departures for Durham, NC to Harrisburg, PA buses for tomorrow, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 AM Durham, NC | 11h30 | 8:45 PM Harrisburg, PA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Durham, NC to Harrisburg, PA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Durham, NC to Harrisburg, PA
Distance 315 miles (507 km) |
Average bus duration 11h 30m |
Cheapest ticket price $220 (€180) |
Buses per day 4 |
Fastest bus 11h 30m |
First bus 01:25 |
Last bus 23:20 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Durham, NC to Harrisburg, PA start from as low as $220 (€180) if booked well in advance.
- Standard Fares: Typically, trains cost $220 (€180) depending on the train type and class.
Bus providers: Greyhound from Durham, NC to Harrisburg, PAYou can travel by bus between Durham, NC to Harrisburg, PA with Greyhound for as low as $220 (€180). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Durham, NC to Harrisburg, PA
Find answers to the most common questions about traveling from Durham, NC to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Pennsylvania State Capitol, an architectural marvel featuring a grand dome and exquisite interior murals
- National Civil War Museum, a comprehensive museum offering insights into the American Civil War with extensive exhibits
- The State Museum of Pennsylvania, showcasing the state's history, art, and natural sciences through diverse collections
- Fort Hunter Mansion and Park, a historic site with preserved buildings and beautiful grounds reflecting 18th and 19th-century life
- Wildwood Park, a nature preserve offering trails and a nature center for wildlife observation and environmental education.
- City Island, a recreational area featuring sports facilities, walking trails, and riverboat cruises
- Whitaker Center for Science and the Arts, a venue offering interactive science exhibits and live performances
- Broad Street Market, one of the oldest continuously operating farmers' markets in the country, offering diverse local foods and goods
- Susquehanna Art Museum, presenting contemporary art exhibitions and educational programs
- Riverfront Park, ideal for walking, biking, and enjoying views of the Susquehanna River.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Durham, NC to Harrisburg, PA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Durham, NC to Harrisburg, PA
Most popular bus connections from Durham, NC
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