- Must visit
The State Museum Of Pennsylvania
The Commonwealth’s flagship history museum with exhibits on archaeology, industry, Civil War history, natural history, and fine art. A strong first stop for understanding Pennsylvania’s story.
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The cheapest and fastest buses from Durham, NC to Harrisburg, PA
Showing times and prices for Jun 21
Cheapest price
$78
Average price
$78
Fastest journey
10 h 5 m
Average duration
10 h 5 m
Buses per day
1
Distance
507 km
Cheap tickets
The best way to find a cheap bus ticket from Durham, NC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Harrisburg, PA will cost around $78 if you buy it on the day, but the cheapest tickets can be found for only $78.
Fast buses
It's difficult to get from Durham, NC to Harrisburg, PA without transferring at least once.
3:50 AM10h05Durham, NC1:55 PMHarrisburg, PA$781One-way1 transfer
- 3:50 AM10h05Durham, NC1:55 PMHarrisburg, PA$781One-way1 transfer
Travel Information
Compare bus, train, and flight for Durham, NC to Harrisburg, PA
Omio recommends booking the flight as it is the most popular option from Durham, NC to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $82. For those with little time consider booking a flight which can get you there in 11h 20m. The ticket price range depends on the travel mode: a bus costs an average of $82, and a flight costs an average of $390.
Distance: 315 miles (507 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$150 Average price Cheapest | $539 Average price | $219 Average price | $74 Average price (fuel + tolls) |
18h 5m Average total duration 17h 35m Onboard + 30m Additional time* | 14h 20m Average total duration Fastest 11h 20m Onboard + 3h 0m Additional time* | 14h 57m Average total duration 14h 27m Onboard + 30m Additional time* | 5h 45m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Durham, NC to Harrisburg, PA is a bus with an average price of $150 (€123).
This is compared to other travel options from Durham, NC to Harrisburg, PA:
A bus is $69 (€56) less than a train for this route with tickets for a train from Durham, NC to Harrisburg, PA costing on average $219 (€179).
A bus is $389 (€318) less than a flight for this route with tickets for a flight from Durham, NC to Harrisburg, PA costing on average $539 (€441).
The fastest way to travel from Durham, NC to Harrisburg, PA is by flight with an average journey time of 11h 20m.
Other travel options to Harrisburg, PA take longer:
Train takes on average 14h 27m.
Bus takes on average 17h 35m.
It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Harrisburg, PA including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from Durham, NC to Harrisburg, PA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Durham, NC to Harrisburg, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 05:55PM | Duration 16h40 | Departure days Wed | Cheapest price $166 |
Operator Flixbus USA | Departure Time 03:50AM | Arrival Time 01:55PM | Duration 10h05 | Departure days Mon, Sun | Cheapest price $78 |
Operator Greyhound | Departure Time 01:10PM | Arrival Time 06:25AM | Duration 17h15 | Departure days Wed | Cheapest price $173 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 07:25AM | Duration 17h15 | Departure days Fri | Cheapest price $193 |
Operator Greyhound | Departure Time 09:05PM | Arrival Time 04:20PM | Duration 19h15 | Departure days Thu, Sat | Cheapest price $82 |
Live departures
Durham, NC to Harrisburg, PA bus times
The table below shows live departures for Durham, NC to Harrisburg, PA buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 9:05 PM Durham, NC | 19h15 | 4:20 PM Harrisburg, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Durham, NC to Harrisburg, PA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Durham, NC to Harrisburg, PA buses with Omio?
FlixBus operates all buses services from Durham, NC to Harrisburg, PA.
Omio is an official ticket reseller for all your travel options from Durham, NC to Harrisburg, PA.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Durham, NC to Harrisburg, PA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Durham, NC to Harrisburg, PA.
Journey information
Overview: Bus from Durham, NC to Harrisburg, PA
USAUSA
Buses from Durham, NC to Harrisburg, PA run on average 3 times per day, taking around 17h 35m. Cheap bus tickets for this journey start at $82 (€67) if you book in advance.
The earliest bus runs at 03:05, the last at 23:20. The fastest bus covers the 315 miles (507 km) distance in 15h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 315 miles (507 km) |
Average bus duration 17h 35m |
Cheapest ticket price $82 (€67) |
Buses per day 3 |
Fastest bus 15h 50m |
First bus 3:05 AM |
Last bus 11:20 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Durham, NC to Harrisburg, PAYou can travel by bus between Durham, NC to Harrisburg, PA with FlixBus for as low as $82 (€67). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 40m
Cheapest Price
$166 (€136)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Harrisburg
Things to do in Harrisburg
Discover the best of Harrisburg — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg trip today.
- Must visit
National Civil War Museum
Major museum interpreting the American Civil War from multiple perspectives, with extensive artifacts, documents, and rotating exhibitions. One of Harrisburg’s best-known cultural attractions.
- Recommended
Susquehanna Art Museum
Contemporary art museum featuring regional, national, and international artists in a modern downtown space. A good choice for travelers interested in current exhibitions and local creative culture.
- Must visit
Riverfront Park
Linear park along the Susquehanna River with walking paths, public art, and excellent skyline views. It is one of Harrisburg’s most pleasant and photogenic places for a stroll.
- Must visit
City Island
Recreational island in the Susquehanna offering river views, trails, and open space between downtown and the west shore. Popular for relaxed walks and classic Harrisburg scenery.
- Must visit
Capitol Complex
The ceremonial and governmental heart of Harrisburg, with landscaped grounds, monuments, and some of the city’s best architecture. A practical and scenic area for sightseeing.
Pennsylvania Dutch Chicken Pot Pie
A regional staple made with broad noodles simmered in rich chicken broth, often with chicken and vegetables. It is a classic Central Pennsylvania comfort dish.
- Gluten-free
Lebanon Bologna
A smoky, tangy cured beef sausage from nearby Lebanon County, traditionally sliced for sandwiches or cheese boards. It is one of the area's best-known local meats.
- Vegetarian
Shoofly Pie
A Pennsylvania Dutch dessert pie with a molasses filling and crumb topping. It is strongly associated with the region's baking traditions.
Rubicon
A well-regarded fine dining spot offering contemporary American cuisine, craft cocktails, and a polished but comfortable atmosphere.
The Millworks
A popular restaurant, brewery, and arts space known for seasonal Pennsylvania ingredients, house beer, and a lively industrial-chic atmosphere.
Bricco
An established downtown Italian restaurant and wine bar known for brick-oven pizzas, handmade pasta, and an intimate urban setting.
United States Dollar
Generally moderate for U.S. travel. Meals and coffee are reasonable, while hotels can rise during events or peak government travel periods.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-35 per person at a casual restaurant.
- Fine dining
- USD 50-90 per person at upscale spots.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants for table service, 15-20% for taxis, USD 1-2 per drink at bars, and a few dollars for hotel staff. Tipping is not expected at most fast-food counters.
FAQs: Bus from Durham, NC to Harrisburg, PA
Find answers to the most common questions about traveling from Durham, NC to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Durham, NC to Harrisburg, PA can start from as little as $82 (€67) when you book in advance. The average bus ticket price for Durham, NC to Harrisburg, PA is $150 (€123) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Durham, NC to Harrisburg, PA is 15h 50m to travel the 315 miles (507 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Durham, NC to Harrisburg, PA leaves at 3:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Durham, NC to Harrisburg, PA leaves at 11:20 PM.
There are 3 buses a day from Durham, NC to Harrisburg, PA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Durham, NC to Harrisburg, PA, you can count on FlixBus for the best way to get you to Harrisburg, PA. You can also check all possible bus companies who offer a service between Durham, NC and Harrisburg, PA and compare the amenities they offer before buying a bus ticket.
A trip to Harrisburg, PA from Durham, NC is worth doing but not as a day trip with a journey time of 15h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Durham, NC to Harrisburg, PA is February.
It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Harrisburg, PA including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Durham, NC to Harrisburg, PA for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Durham, NC to Harrisburg, PA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Harrisburg, PA are:
- Pennsylvania State Capitol, an architectural marvel featuring a grand dome and exquisite interior murals
- National Civil War Museum, a comprehensive museum offering insights into the American Civil War with extensive exhibits
- The State Museum of Pennsylvania, showcasing the state's history, art, and natural sciences through diverse collections
- Fort Hunter Mansion and Park, a historic site with preserved buildings and beautiful grounds reflecting 18th and 19th-century life
- Wildwood Park, a nature preserve offering trails and a nature center for wildlife observation and environmental education.
The best things to do in Harrisburg, PA include:
- City Island, a recreational area featuring sports facilities, walking trails, and riverboat cruises
- Whitaker Center for Science and the Arts, a venue offering interactive science exhibits and live performances
- Broad Street Market, one of the oldest continuously operating farmers' markets in the country, offering diverse local foods and goods
- Susquehanna Art Museum, presenting contemporary art exhibitions and educational programs
- Riverfront Park, ideal for walking, biking, and enjoying views of the Susquehanna River.
Whether you can cancel your bus ticket from Durham, NC to Harrisburg, PA depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Durham, NC to Harrisburg, PA.
Yes, the following luggage options are included when booking a bus ticket from Durham, NC to Harrisburg, PA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Durham, NC to Harrisburg, PA:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Durham, NC to Harrisburg, PA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Durham, NC to Harrisburg, PA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Durham, NC to Harrisburg, PA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Durham, NC to Harrisburg, PA with the following bus company: FlixBus.
Since neither Durham, NC nor Harrisburg, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Durham, NC to Harrisburg, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Harrisburg, PA, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overpriced taxi services and fraudulent ticket sellers near popular attractions. Staying aware of surroundings and using authorized transportation options helps enhance safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Durham, NC to Harrisburg, PA
Durham
Harrisburg
The major bus station for departures in Durham is Durham, W Pettigrew St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Durham, W Pettigrew St (Greyhound Bus Station) for your trip from Durham to Harrisburg.
Durham, W Pettigrew St (Greyhound Bus Station)
information
The major bus station for arrivals in Harrisburg is Harrisburg, Market St (Bus Station). Find all the information you need to know about services, amenities and connections at Harrisburg, Market St (Bus Station) for your trip to Harrisburg from Durham.
Harrisburg, Market St (Bus Station)
information
Harrisburg, Chestnut Street / South 4th Street
information
Most popular bus connections from Durham, NC
More options for your journey from Durham, NC to Harrisburg, PA
Here are some other resources that might have the information you need
Most popular buses to and from Harrisburg, PA and Durham, NC
Most popular bus connections to Harrisburg, PA
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