Durham, NC to Harrisburg, PA bus with FlixBus

Wed, Aug 05
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Rede Expressos
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from Durham, NC to Harrisburg, PA

Showing times and prices for Aug 05

Cheapest price

€141

Average price

€141

Fastest journey

17 h 15 m

Average duration

17 h 15 m

Buses per day

1

Distance

507 km

Cheap tickets

The best way to find a cheap bus ticket from Durham, NC to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Durham, NC to Harrisburg, PA will cost around €141 if you buy it on the day, but the cheapest tickets can be found for only €141.

Fast buses

Of the 1 buses that leave Durham, NC for Harrisburg, PA on Wed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Aug 05 the direct buses cover the 507 km distance in an average of 17 h 15 m but if you time it right, some buses will get you there in just 17 h 15 m .

On Wed, Aug 05 the slowest buses will take 17 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    1:10 PM17h15
    Durham, NC
    6:25 AMHarrisburg, PA
    1411One-way
    0 transfers

Journey information

Overview: Bus from Durham, NC to Harrisburg, PA

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Buses from Durham, NC to Harrisburg, PA run on average 3 times per day, taking around 17h 35m. Cheap bus tickets for this journey start at €67 if you book in advance.

The earliest bus runs at 03:05, the last at 23:20. The fastest bus covers the 315 miles (507 km) distance in 15h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
315 miles (507 km)
Average bus duration
17h 35m
Cheapest ticket price
€67
Buses per day
3
Fastest bus
15h 50m
First bus
3:05 AM
Last bus
11:20 PM
Cheapest Month
Feb
Cheapest Day
Thu
High Season
Jan - Mar
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Durham, NC to Harrisburg, PA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
01:15AM
Arrival Time
05:55PM
Duration
16h40
Departure days
Wed
Cheapest price
136
Operator
Flixbus USA
Departure Time
03:50AM
Arrival Time
01:55PM
Duration
10h05
Departure days
Mon, Sun
Cheapest price
64
Operator
Greyhound
Departure Time
01:10PM
Arrival Time
06:25AM
Duration
17h15
Departure days
Wed
Cheapest price
141
Operator
Greyhound
Departure Time
02:10PM
Arrival Time
07:25AM
Duration
17h15
Departure days
Fri
Cheapest price
158
Operator
Greyhound
Departure Time
09:05PM
Arrival Time
04:20PM
Duration
19h15
Departure days
Thu, Sat
Cheapest price
67

Why should you book Durham, NC to Harrisburg, PA buses with Omio?

FlixBus operates all buses services from Durham, NC to Harrisburg, PA.
Omio is an official ticket reseller for all your travel options from Durham, NC to Harrisburg, PA.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Durham, NC to Harrisburg, PA.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Durham, NC to Harrisburg, PA.

Bus providers: FlixBus from Durham, NC to Harrisburg, PAYou can travel by bus between Durham, NC to Harrisburg, PA with FlixBus for as low as €67. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 40m
Cheapest Price
€136
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Harrisburg, PA

Things to do in Harrisburg, PA

Discover the best of Harrisburg, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Harrisburg, PA trip today.

  • Must visit

The State Museum of Pennsylvania

Major regional museum with American art, natural history, and science exhibits. It is Harrisburg's best-known museum and a strong all-ages visit.

  • Must visit

National Civil War Museum

National Civil War museum with broad exhibits on soldiers, civilians, and the war's legacy. It is one of the city's most important history stops.

  • Recommended

Fort Hunter Mansion and Park Museum

Museum at Fort Hunter highlighting local river history, mansion life, and the Susquehanna landscape. A quieter favorite with a scenic setting.

US dollar ($)

Moderate for US state capitals; hotels and dining are usually below major East Coast cities, while transit needs and limited cheap tourist areas can raise daily costs.

Average meal costs

Budget
$10-15 for fast food or a simple lunch.
Mid-range
$18-35 per person for a casual restaurant meal.
Fine dining
$50+ per person for upscale dining.
Coffee
$3-5 for coffee or a cappuccino.

Tipping culture

Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if service is provided.

FAQs: Bus from Durham, NC to Harrisburg, PA

Find answers to the most common questions about traveling from Durham, NC to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Durham, NC to Harrisburg, PA can start from as little as €67 when you book in advance. The average bus ticket price for Durham, NC to Harrisburg, PA is €123 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Durham, NC to Harrisburg, PA is 15h 50m to travel the 315 miles (507 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Durham, NC to Harrisburg, PA leaves at 3:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Durham, NC to Harrisburg, PA leaves at 11:20 PM.
There are 3 buses a day from Durham, NC to Harrisburg, PA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Durham, NC to Harrisburg, PA, you can count on FlixBus for the best way to get you to Harrisburg, PA. You can also check all possible bus companies who offer a service between Durham, NC and Harrisburg, PA and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Harrisburg, PA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Durham, NC to Harrisburg, PA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Durham, NC to Harrisburg, PA for bus company FlixBus.
Whether you can cancel your bus ticket from Durham, NC to Harrisburg, PA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Durham, NC to Harrisburg, PA.
Yes, the following luggage options are included when booking a bus ticket from Durham, NC to Harrisburg, PA:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Durham, NC to Harrisburg, PA:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Durham, NC to Harrisburg, PA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Durham, NC to Harrisburg, PA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Durham, NC to Harrisburg, PA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Durham, NC to Harrisburg, PA with the following bus company: FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Harrisburg, PA, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overpriced taxi services and fraudulent ticket sellers near popular attractions. Staying aware of surroundings and using authorized transportation options helps enhance safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Durham, NC to Harrisburg, PA

Most Durham, NC to Harrisburg, PA buses use the Durham, W Pettigrew St (Greyhound Bus Station) to Harrisburg, Market St (Bus Station) station pair, with some services arriving at Harrisburg, Chestnut Street / South 4th Street. Use this guide to compare Durham, NC and Harrisburg, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Durham
Arrival bus stations in Harrisburg
Durham, W Pettigrew St (Greyhound Bus Station)Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701
City-centre transport

Getting to Durham, W Pettigrew St (Greyhound Bus Station) from Durham city centre

Bus2, 9, 12, 12B · 5m · €1 · every ~12 min

More options for your journey from Durham, NC to Harrisburg, PA

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