Compare prices and tickets Durham, NC to Charleston, SC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 17
Dec 18
Dec 19
Dec 20
Dec 21
Dec 22
Dec 23
Why should you book Durham to Charleston trains with Omio?
Amtrak operates all train services from Durham to Charleston. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
Journey information
Overview: Train from Durham, NC to Charleston, SC
Take a train from Durham, NC to Charleston, SC and enjoy the approximately 229 miles (370 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 09:15, the last at 09:47.
Distance 229 miles (370 km) |
Average train duration 6h 21m |
Trains per day 2 |
First train 09:15 |
Last train 09:47 |
Train companies: Amtrak from Durham, NC to Charleston, SC trainsAmtrak trains will get you between Durham, NC and Charleston, SC from $89 (€71). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Durham, NC to Charleston, SC
Find answers to the most common questions about traveling from Durham, NC to Charleston, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Durham, NC to Charleston, SC
- 6:30 AM - 9:00 PM Monday - Sunday
- Free
- Parking is available nearby, with several public parking options in the vicinity.
- Parker and Otis
- Dame's Chicken & Waffles
- Outside the main entrance.
- Ramps.
- Free of charge
- Durham Marriott City Center
- 21c Museum Hotel Durham
- Aloft Durham Downtown
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticketing, and waiting area
- Hall 2: platform access
- Bus: GoDurham buses available
- Amtrak Thruway buses
More options for your journey from Durham, NC to Charleston, SC
Here are some other resources that might have the information you need
