Des Moines, IA to Buffalo, NY bus with Greyhound

Sun, Mar 22
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2,000+ travel companies
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The cheapest and fastest buses from Des Moines, IA to Buffalo, NY

Showing times and prices for Mar 22

Cheapest price

$181

Average price

$181

Fastest journey

1 d 5 h 45 m

Average duration

1 d 5 h 45 m

Buses per day

1

Distance

1219 km

Cheap tickets

The best way to find a cheap bus ticket from Des Moines, IA to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Des Moines, IA to Buffalo, NY will cost around $181 if you buy it on the day, but the cheapest tickets can be found for only $181.

Fast buses

Of the 1 buses that leave Des Moines, IA for Buffalo, NY on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sun, Mar 22 the direct buses cover the 1219 km distance in an average of 1 d 5 h 45 m but if you time it right, some buses will get you there in just 1 d 5 h 45 m .

On Sun, Mar 22 the slowest buses will take 1 d 5 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
03:30PM29h45
Des Moines, IA
09:15PMBuffalo, NY
$1811One-way
0 transfers

Travel Information

Compare bus and flight for Des Moines, IA to Buffalo, NY

Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $139. For those with little time consider booking a flight which can get you there in 4h 18m. The ticket price range depends on the travel mode: a bus costs an average of $139, and a flight costs an average of $361.

Distance: 757 miles (1219 km)

Compare bus with

Most popular
Bus
Flight

$150

Average price

Cheapest

$366

Average price

32h 40m

Average total duration

32h 10m

Onboard

+

30m

Additional time*

7h 18m

Average total duration

Fastest

4h 18m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Live departures

Des Moines, IA to Buffalo, NY bus times

The table below shows live departures for Des Moines, IA to Buffalo, NY buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at 6:12 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus3:30 PM Des Moines, IA
29h45
9:15 PM Buffalo, NY0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Des Moines, IA to Buffalo, NY by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Mar 22
Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28

Why should you book Des Moines, IA to Buffalo, NY buses with Omio?

Greyhound operates all buses services from Des Moines, IA to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from Des Moines, IA to Buffalo, NY.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Buffalo, NY.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Buffalo, NY.

Journey information

Overview: Bus from Des Moines, IA to Buffalo, NY

USAUSA
USAUSA
Icon of bus

Buses from Des Moines, IA to Buffalo, NY run on average 1 times per day, taking around 32h 10m. Cheap bus tickets for this journey start at $139 (€113) if you book in advance.

The earliest bus runs at 04:45, the last at 23:55. The fastest bus covers the 757 miles (1219 km) distance in 29h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
757 miles (1219 km)
Average bus duration
32h 10m
Cheapest ticket price
$139 (€113)
Buses per day
1
Fastest bus
29h 50m
First bus
04:45
Last bus
23:55
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Des Moines, IA to Buffalo, NYYou can travel by bus between Des Moines, IA to Buffalo, NY with Greyhound for as low as $139 (€113). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
29h 50m
Cheapest Price
$139 (€113)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Des Moines, IA to Buffalo, NY

Find answers to the most common questions about traveling from Des Moines, IA to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Buffalo, NY can start from as little as $139 (€113) when you book in advance. The average bus ticket price for Des Moines, IA to Buffalo, NY is $150 (€122) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Buffalo, NY is 29h 50m to travel the 757 miles (1219 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Buffalo, NY leaves at 4:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Buffalo, NY leaves at 11:55 PM.
There are 1 buses a day from Des Moines, IA to Buffalo, NY which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Des Moines, IA to Buffalo, NY, you can count on Greyhound for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between Des Moines, IA and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
A trip to Buffalo, NY from Des Moines, IA is worth doing but not as a day trip with a journey time of 29h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Buffalo, NY is February.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Buffalo, NY including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Des Moines, IA to Buffalo, NY:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Des Moines, IA to Buffalo, NY for bus company Greyhound.
Whether you can cancel your bus ticket from Des Moines, IA to Buffalo, NY depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Des Moines, IA to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from Des Moines, IA to Buffalo, NY:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Des Moines, IA to Buffalo, NY:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Buffalo, NY.
You can reserve your seat on the bus from Des Moines, IA to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Des Moines, IA to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Des Moines, IA to Buffalo, NY with the following bus company: Greyhound.

popular bus stations

Popular bus stations from Des Moines, IA to Buffalo, NY

Des Moines
Buffalo
Buffalo, NFTA Metro Center
information
Cheektowaga, BNIA Drway & BNIA Terminal
information

More options for your journey from Des Moines, IA to Buffalo, NY

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